Mayo Clinic Bioservices

Mayo Clinic and the Center for Individualized Medicine have made a significant commitment to building a world-class, scalable biorepository infrastructure. All of the services and resources from the Biorepositories Program are now available to external investigators through Mayo Clinic Bioservices.

Our mission is to provide world-class biorepositories and state-of-the-art biospecimen processing and storage with a focus on quality and service.

Laboratory services

Our laboratory services combine specimen accessioning, processing, nucleic acid extraction, specimen tracking, storage and shipping in a highly integrated core laboratory vital to basic, translational and epidemiologic research. Our laboratory services also include a variety of histology and tissue-based services.

Available laboratory services:

  • Consultation
  • Accessioning
  • DNA and RNA purifications
  • Immunostaining
  • Digital image capture and analysis
  • Blood and bodily fluid processing
  • Tissue handling
  • Tissue microarray construction
  • Frozen and paraffin sectioning
  • Custom development and optimization of new antibodies

Storage services

Mayo Clinic Bioservices' central storage facility offers many advantages, including efficiency, automation, uniformity, and highly standardized procedures and processes. A variety of sample storage solutions include liquid nitrogen, conventional freezers and robotically controlled freezers. Sample shipping is supported by a national network of courier services.

Kits for sample collection and processing can be prepared to include specific collection containers and processing vials, study-specific paperwork and instructions, and return shipping materials. These kits may be shipped directly to the end user or provided to the study team.

Biobanks

The Mayo Clinic Biobank offers biological samples of DNA, serum, plasma (including platelet-poor plasma) and an aliquot of frozen white blood cells. Data available from the electronic medical record includes medications, diagnoses, laboratory tests and administrative data, as well as patient-provided information about current health, family health history and other disease risk factors. The Biobank's goal is to enroll 50,000 participants by 2015 to support a wide array of health-related research studies.

The Mayo Clinic Cancer/Normal Serum Bank includes approximately 130,000 frozen vials of serum from approximately 17,000 unique Mayo patients (approximately 24,000 blood draws), representing 85 different malignant and benign conditions between 1975 and 1990. These serum specimens are available to researchers.

Bioethics and genetic counseling

Mayo Clinic's Bioethics Program coordinates community engagement activities related to biobanking and ensures community representation in biobank governance. The staff has extensive experience integrating genomic technologies into research and medicine, with a keen focus on patient interests.

Genetic counselors are actively involved in the day-to-day management of Mayo Clinic biobanks, including review of researcher access to samples and the development and implementation of return-of-results policies and procedures. They create and review study materials as well as information for participants and researchers.

Available consultative services:

  • Patient recruitment and informed consent development
  • Biobanking regulatory requirements
  • Biobank governance and oversight
  • Patient outreach and communications
  • Return of results policies and procedures

Contact

For more information, contact:

Mayo Clinic Bioservices
200 First St. SW
Rochester, MN 55905
Phone: 855-298-0598 (toll-free)