Personalized Medicine

Better diagnoses, earlier interventions, more-efficient drug therapies, customized treatment plans. These are the promises of personalized medicine.

Individualized or personalized medicine provides a genomic blueprint to determine each person's unique disease susceptibility, define preventive measures and enable targeted therapies to promote wellness.

Mayo Clinic has provided personalized medicine to every one of its patients for nearly 150 years. But in recent years, advances in genomic and clinical science have created innovative opportunities to further tailor health care to each patient.

The Center for Individualized Medicine at Mayo Clinic is taking the practice of personalized medicine and applying it to the entire spectrum of health care using sophisticated methods of genomic sequencing and molecular analysis.

Patient Stories

  • Applied pharmacogenomics resolves patient's lifelong anxiety and depression.
  • Microbiome transplant clears antibiotic-resistant intestinal infection.
  • Genome sequencing reveals rare gene mutation.
  • Sequencing uncovers genetic makeup of aggressive tumor.

Personalized Medicine Concepts

  • The Biomarker Discovery Program captures genetic information from cells and analyzes it, searching for genetic patterns to help physicians make more precise diagnoses and prescribe more effective, individualized treatments.
  • The Microbiome Program explores the genetic code of the body's microorganisms, using the latest techniques to profile an individual's microbiome to detect, prevent and diagnose infections and other diseases.
  • The Pharmacogenomics Program investigates how variations in genes affect response to medications, thereby using a patient's genetic profile to predict a drug's efficacy, guide dosage and improve patient safety.
  • Genomic sequencing is a process for analyzing a sample of DNA taken from your blood. In the lab, technicians extract DNA and prepare it for sequencing.
  • The Clinomics Program quickly moves discoveries from the research lab to the clinical setting, with practical, cost-efficient genomic tests for diagnosing and treating patients.
  • The Epigenomics Program investigates the role of the epigenome, examines which factors act on individual genes, and how certain changes in the epigenome affect our health.

Personalized Medicine 101

  • Personalizing care, preventing disease
  • Living better, living longer

Center for Individualized Medicine Programs

  • George Vasmatzis, Ph.D., co-director, Biomarker Discovery Program
  • Matthew J. Ferber, Ph.D., and Eric D. Wieben, Ph.D., co-directors, Clinomics Program
  • Tamas Ordog, M.D., director, Epigenomics Program
  • Heidi Nelson, M.D., director, Microbiome Program
  • Richard Weinshilboum, M.D., director, Pharmacogenomics Program
  • Richard Sharp, Ph.D., director, Bioethics Program
  • Jean-Pierre A. Kocher, Ph.D., director, Bioinformatics Program
  • James R. Cerhan, M.D., Ph.D., co-director, Biorepositories Program
  • James D. Buntrock, director, Information Technology Program
  • Eric D. Wieben, Ph.D., director, Medical Genome Facility