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Completed Studies

IRB # Completed Study Title PI Study Coordinator
226-06 The Incidence and Risk Factors for Laryngospasm Among Children During General Anesthesia Randall Flick, M.D. Shonie Buenvenida
07-002858 DEX-06-09: A Phase III, Randomized, Double-Blind, Placebo-Controlled, Two-arm Parallel, Multicenter Study Evaluating the Efficacy and Safety of Dexmedetomidine in the Prevention of Postoperative Delirium in Subjects Undergoing Surgery for Fractured Hip with General Anesthesia Christopher J. Jankowski, M.D. Shonie Buenvenida
1880-04 Elder Surgery - Functional Recovery Following Beta-Blockade Christopher J. Jankowski, M.D. Shonie Buenvenida
1866-05 Outcomes of Intraoperative Cardiac Arrests in Children (1988-2005) Randall Flick, M.D. Shonie Buenvenida
07-001195 Randomized Evaluation of a Low-frequency Investigational Device Employing Neuro-modulation Therapy in Patients with Fibromyalgia (RELIEF) David P. Martin, M.D., Ph.D. Anita Baumgartner
2482-05 Comparison of SAPS and APACHE IV and Evaluation of the Influence of "Do Not Resuscitate" Orders at a Teritary Referral Center Mark T. Keegan, M.D. Anita Baumgartner
988-04 Pilot Study - Effect of a pulmonary rehabilitation program on patient outcomes following pneumonectomy or lobectomy in patients with pre-existing lung disease Francis C. Nichols, M.D. Melissa Passe
2247-05 Restrictive Versus Liberal Fresh Frozen Plasma Transfusion Prior to Low-Risk Invasive Procedures in Hospitalized Patients Ognjen Gajic, M.D. Dave Folkert,
Greg Wilson
416-03 Ventilator Management in Patients Receiving Mechanical Ventilation During Anesthesia Ognjen Gajic, M.D. Greg Wilson
06-002743 Normoglycemia in Intensive Care Evaluation Survival Using Glucose Algorithm Regulation. Nicholas E. Vlahakis, M.D. Laurie Meade
1896-05 "A Prospective Study of Low Dose Ketamine as an Adjunct to Fentanyl in Pediatric Patients Following Outpatient Tonsillectomy and Adenoidectomy" Gregory J. Schears, M.D. Laurie Meade
06-002738 Pilot Study of Transforaminal Epidural Injection of Clonidine for the Treatment of Acute Lumbosacral Radiculopathy Marc A. Huntoon, M.D., Abram H. Burgher, M.D. Greg Wilson,
Dave Folkert,
Melissa Passe
719-03 Alveolar Recruitment Maneuver and Arterial Oxygenation in Morbidly Obese Patients Undergoing Open or Laparoscopic Abdominal Surgery Juraj Sprung, M.D., Ph.D. Lavonne Liedl
07-000144 Comparison of Medical Student Preparedness Between A European Country and the United States Juraj Sprung, M.D., Ph.D. Shonie Buenvenida
06-003985 Organon Protocol 021048: An open-label, randomized, phase IIIB, multicenter trial to evaluate the pharmacodynamic parameters of intubation bolus, and bolus and infusion maintenance doses of Zemuron in pediatric and adolescent subjects Randall Flick, M.D. Shonie Buenvenida
06-004329 Hospira Clinical Study Protocol 2005-006 - A Phase III, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study Evaluating the Sfety and Efficacy of Dexmedetomidine Used for Sedation During Elective Awake Fiberoptic Intubation Juraj Sprung, M.D., Ph.D. Shonie Buenvenida
06-006390 Protocol Name: A Phase III, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety and Efficacy of Dexmedetomidine for Sedation During Monitored Anesthesia Care Juraj Sprung, M.D., Ph.D. Shonie Buenvenida
2708-04 "Observation of Complications in Standard IV Securement" Gregory J. Schears, M.D. Laurie Meade
06-004186 Changes in Red Blood Cell Transfusion Practice During the Past Two Decades. James Y. Findlay, M.B.Ch.B. Laurie Meade
1513-04 "A Prospective Randomized Trial Comparing Statlock vs. Tape Securement of Peripheral Intravenous Catheters" Gregory J. Schears, M.D. Laurie Meade
07-001140 Minnesota SAFE TRIPS Saline and Fluid Evaluation Translation of Research Into Practice Study Nicholas E. Vlahakis, M.D. Laurie Meade
2130-04 Strategies to Reduce Transmission of Antimicrobial Resistant Bacteria in Intensive Care Units (STAR*ICU) Trial W C. Huskins, M.D. Anita Baumgartner,
Shonie Buenvenida
2425-03 A Prospective, Randomized, Single-Center Study of the Vaxcel Peripherally Inserted Catheter(PICC) with the PASV Valve Compared to a Clamped Valve Gregory J. Schears, M.D. Laurie Meade
683-99 Efficacy of rHuEPO in the Critically Ill Patient: A Randomized, Double-Blind Placebo-Controlled Trial Michael J. Murray, M.D., Ph.D., Marie L. De Ruyter, M.D.  
1949-99 Efficacy and Neurologic Complications of Neuraxial Anesthesia and Analgesia in Patients with Spinal Cord and Lumbosacral Root Pathology James R. Hebl, M.D.  
1489-00 A Prospective, Multicenter Study of the Anemia of Critical Illness and Transfusion in the Critically Ill Patient Timothy R. Aksamit, M.D.  
503-99 Multicenter, Prospective, Randomized, Controlled Pivotal Trial for Efficacy of Partial Liquid Ventilation (PLV) with Low and High Doses of Perflubron in Adult Patients with Acute Lung Injury Michael J. Murray, M.D., Ph.D.  
203-01 Intrathecal Anesthesia and Recovery from Nephrectomy: A Prospective, Randomized Controlled Trial Daniel R. Brown, M.D., Ph.D.  
765-00 Multicenter, Double-Blind, Placebo-Controlled, Randomized, Phase 3 Study of Tifacogin (Recombinant Tissue Factor Pathway Inhibitor [rTFPI/CI-59735]) in Severe Sepsis Michael J. Murray, M.D., Ph.D.  
1637-98 Multicenter, Single Blind, Placebo-Controlled, Randomized, Dose Escalation Study of Recombinant Tissue Factor Pathway Inhibitor (rTFPI/SC-59735) in Severe Sepsis Michael J. Murray, M.D., Ph.D.  
1042-99 A Phase IIIb, Multicenter, Open-Label, Randomized Study Comparing the Safety and Efficacy of Dexmedetomidine to Propofol-Based Standard of Care for ICU Sedation Following CABG Surgery Michael J. Murray, M.D., Ph.D.  
379-97 The Safety and Efficacy of Electrotransport (E-Trans) Fentanyl Compared to IV PCA Morphine for the Treatment of Postoperative Pain Michael J. Murray, M.D., Ph.D.  
942-98 A Phase 2b Study to Evaluate the Safety and Efficacy of Recombinant Platelet Activating Factor Acetylhydrolase (rPAF-AH) for the Prevention of ARDS in Patients with Severe Sepsis or Severe Traumatic Injuries Michael J. Murray, M.D., Ph.D.  
1533-98 A Novel Assay for the Measurement of Endotoxin in Human Plasma as an Early, Sensitive, and Specific Predictor of Organ Dysfunction Associated Michael J. Murray, M.D., Ph.D.  
1016-98 Nitric Oxide: Its Effects on Hypoxemia Associated with Congenital Heart Repair Michael J. Murray, M.D., Ph.D.  
1142-00 Prospective, Randomized, Multi-Center Trial of Pulmonary Artery Catheter (PAC) vs. Central Venous Catheter (CVC) for Management of Acute Lung Injury (ALI) and Acute Respiratory Distress Syndrome (ARDS) and Prospective, Randomized... Michael J. Murray, M.D., Ph.D.  
1067-98 Multiple Dose Safety, Tolerability, Pharmacokinetics, and pharmacodynamics of PMX 622 in Patients with Severe SIRS and Evidence of Infection Michael J. Murray, M.D., Ph.D., Michael P. Bannon, M.D.  
1083-01 Perioperative Outcome of Cardiac Arrests during Anesthesia for Noncardiac Surgery: A 10-Year Mayo Clinic Experience (1990-2000) Juraj Sprung, M.D., Ph.D.  
735-00 Perioperative Smoking Behavior and Stress David O. Warner, M.D.  
544-00 Long-Term Infusion of Zemuron in Adult ICU Subjects Michael J. Murray, M.D., Ph.D.  
903-00 Intrathecal Anesthesia and Recovery from Radical Prostatectomy: A Prospective, Randomized Controlled Trial Daniel R. Brown, M.D., Ph.D.  
1969-99 Perioperative B-Blocker Therapy and Anesthetic Management and the Incidence of New -Onset Atrial Tachyarrhythmias in Thoracotomy Patients for Lung Resection -- A Pilot Study Daniel R. Brown, M.D., Ph.D.  
705-02 Clinical Study of NOX-100 for the Treatment of Distributive Shock Due to Sepsis Bekele Afessa, M.D.  
1348-00 Perioperative Analgesia After Total Knee Arthroplasty-A Comparison of Intravenous Patient-Controlled Analgesia, Single Dose and Continuous Psoas Blockade, and Continuous Epidural Analgesia Terese T. Horlocker, M.D.  
749-00 Bioavailability of Levofloxacin in Critically Ill Patients and the Effects of Enteral Nutrition Oyen,L  
1231-02 Smoking and the Regulation of Skin Blood Flow David O. Warner, M.D.  
1147-03 Effect of Angiotensin Converting Enzyme Inhibition on Blood Pressure During General Anesthesia.

Juraj Sprung, M.D., Ph.D., Muthuswamy Kumar, M.D.

 
127-01 Effect Of Anesthetic Technique On Long-Term Postoperative Analgesia After Vaginal Hysterectomy Juraj Sprung, M.D., Ph.D. Lavonne Liedl
941-02 Effect of Cerebrospinal Fluid Pressure in Sensorineural Hearing Juraj Sprung, M.D., Ph.D. Lavonne Liedl
878-03 Xigris Evaluation in the United States Bekele Afessa, M.D. Lavonne Liedl
1465-00 Smoking Cessation in Surgical Patients David O. Warner, M.D. Anita Baumgartner
1047-01 A Pilot Study to Evaluate the Effects of Epidural Corticosteroid Injections on Pain Relief and Quality of Life in Patients with Acute Herpes Zoster Wong,G Anita Baumgartner
257-03 Serum Vasopressin Concentrations During the Perioperative Period Daniel R. Brown, M.D., Ph.D. Steve Holets
726-03 Comparison of Calibrated Loop and Serial Dilution Techniques for Quantitative Culture of Bronchoalveolar Lavage Fluid Bekele Afessa, M.D. Steve Holets
652-02 A Prospective Randomized Double-Blinded Controlled Evaluation of Acupuncture for Patients with Fibromyalgia David P. Martin, M.D., Ph.D. Greg Wilson
169-03 Multi-Center Clinical Trial of the Bard, Silver Coated Endotracheal Tube to Reduce Ventialtor Associated Pnuemonia - Protocol 5003A, Dated 10/08/02 Bekele Afessa, M.D. Greg Wilson
22-05 Comparison of Two approved insulin infusion protocols for glycemic control in critically ill patients Roy, Tuhin Bryan Wattier
1928-05 Microbiological Assessment of the Bard Silver Coated Endotracheal Tube after Extubation
Robin Patel, M.D. Greg Wilson
563-05 Multi-center trial of the Bard Silver Coated Endotracheal Tube to Reduce Ventilator Associated Pneumonia - Health Economics Study Bekele Afessa, M.D. Greg Wilson
1543-01 Changes in Red Blood Cell Transfusion Practice During the Past Two Decades: A Retrospective Analysis of Adult Patients Undergoing Major Spine Surgery Using the Mayo Database C. T. Wass, M.D. Shonie Buenvenida
315-02 Preoperative Cognitive Dysfunction and Postoperative Delirium in Elderly Orthopedic Surgical Patients Christopher J. Jankowski, M.D. Shonie Buenvenida
1919-05 A Multi-Center, Open-label, Phase IIIa Trial to Evaluate the Efficacy and Safety of Org 25969 When Used at the End of Surgical Procedure to Reverse the Neuromuscular Block Induced by Rocuronium Following Routine Anesthesia Juraj Sprung, M.D., Ph.D. Shonie Buenvenida

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