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News, Publications, and Related Stories
Science Blog -- Aug. 24, 2010 The study’s co-principal author, John Copland, Ph.D., a cancer biologist and endocrinologist Robert Smallridge, M.D., the other co-principal author are sharing the new ATC cells with researchers internationally who need them. View Related
Medical Edge Newspaper My 32-year-old son visited his doctor because he was having some rectal bleeding. His doctor performed a flexible sigmoidoscopy and discovered a polyp, which she was not able to remove, but recommended he have a colonoscopy soon. She asked about siblings and family history and said his 37-year-old sister should be checked. How common is it for someone to have polyps at this age? View Related
Mayo Clinic Women's Health Source -- May 11, 2010 Mayo Clinic Women's HealthSource is published monthly to help women enjoy healthier, more productive lives. View Related 
UPI.com -- April 21, 2010 Vitamin K -- found in green leafy vegetables -- may protect against non-Hodgkin lymphoma, U.S. researchers said. View Related 
Mayo Clinic Health Letter -- April 5, 2010 Mayo Clinic Health Letter is an eight-page monthly newsletter of reliable, accurate and practical information on today's health and medical news. View Related
Los Angeles Times -- March 22, 2010 Dr. Donald Hensrud, an associate professor of preventive medicine and nutrition. View Related 
Arizona State University -- Feb. 3, 2010 Dr. Roxanne Lorans, a radiologist with the Mayo Clinic in Arizona, will discuss the intricacies of breast cancer screening and debate the implications of recent revised guidelines. View Related 
MedCity News -- Jan. 14, 2010 Dr. Sandhya Pruthi says mammograms are still the best screening tool to reduce breast cancer deaths. View Related
Mayo Clinic Health Letter -- Jan. 4, 2010 Mayo Clinic Health Letter is an eight-page monthly newsletter of reliable, accurate and practical information on today's health and medical news. View Related 
Wall Street Journal -- Nov. 19, 2009 Sandhya Pruthi, M.D., director of Mayo Clinic Breast Clinic, Rochester, Minn., answers questions related to these new guidelines. View Related 
Mayo task force says women 40 and older should be screened as per usual Mayo Clinic will continue to recommend screening mammograms for women age 40 and older. "Everyday we discover invasive breast cancer in a woman age 40–50," says Sandhya Pruthi, M.D., director of the Breast Clinic at Mayo Clinic in Rochester, and leader of the task force. View Related
UPI -- Nov. 16, 2009 Refers to the Special Report on Cancer Prevention in the November issue of Mayo Clinic Women's HealthSource View Related
Co-Leaders of Two Cancer Center Programs Were Among Those Honored Cancer Center recipients are Charles Loprinzi, M.D., co-leader of the Cancer Prevention and Control Program and Rafael Fonseca, M.D., co-leader of the Hematologic Malignancies Program. View Related
Mayo Clinic Women's HealthSource -- November 2009 Mayo Clinic Women's HealthSource is published monthly to help women enjoy healthier, more productive lives. Revenue from subscriptions is used to support medical research at Mayo Clinic. View Related
Mayo Clinic Women's HealthSource -- November 2009 Mayo Clinic Women's HealthSource is published monthly to help women enjoy healthier, more productive lives. Revenue from subscriptions is used to support medical research at Mayo Clinic. View Related
A diagnosis of Barrett's esophagus can be concerning because it increases the risk of developing esophageal cancer. View Related 
Discovery's Edge - Mayo Clinic's Research Publication Zebrafish make an ideal model organism for genetic and developmental studies. A molecular biologist at Mayo is not only using the fish to investigate new treatments for cancer and nicotine addiction, but also as the foundation of a paradigm to get students excited about science. View Related 
Researchers say this method is more accurate in predicting risk for an individual than the Gail model. View Abstract 
Offering cancer patients in Florida and the Southeast access to investigational therapies through rigorously monitored clinical trials "The cancer field is rapidly moving to use of these new agents as a way to improve upon the success we have seen with more traditional therapies, such as chemotherapy and radiation," says says Michael Menefee, M.D., who heads the Phase I Clinical Trial Program in Oncology at Mayo Clinic, Jacksonville. View Related 
Medical Edge Newspaper I recently read about a stool test that can detect colon cancer without a colonoscopy. Is it just as effective as a colonoscopy, and if so, when will this be an option for everyone? View Related 
Mayo Clinic Cancer Center receives an additional five years of National Cancer Institute (NCI) funding and re-designation as a comprehensive cancer center.
Multi-center study co-authored by Mayo Clinic reveals promising treatment Dysplastic, or pre-cancerous lesions, can lead to esophageal cancer. Radiofrequency ablation is a procedure that uses high-intensity radio waves to zap the lesions. View Related 
Most people associate colorectal cancer screening with invasive colonoscopy, but previous Mayo Clinic research has shown that stool DNA testing can identify both early-stage colorectal cancer and precancerous polyps. View Related 
Medical Edge Newspaper I have the BRCA1 mutation ("breast cancer gene"), which I know increases my risk of getting breast cancer as well as ovarian cancer. A gynecologist recommends I have my ovaries removed as soon as I'm done having children, but another doctor suggests waiting until I'm closer to 40 (I'm 32 now). Are there pros and cons of each option, or is one doctor right? View Related
Ablation technique shown effective for patients with high and low-grade dysplasia 
Medical Edge Newspaper In my 20s and early 30s I was a pack-a-day smoker who tried frequently to quit the habit. For the past 13 years I have smoked only periodically — about six days a year (when getting together with college friends). On those days I smoke about two packs a day. What is the risk to my health posed by those six days of heavy smoking? Can you tell me if the cancer and COPD risks are similar to those of a daily smoker? View Related 
Medical Edge Newspaper I recently heard in the news about a new breast cancer detection method that, according to the report, is really promising. Is this going to replace the mammogram? View Related
Presented at the annual San Antonio Breast Cancer symposium. "Breast cancer is the leading cause of cancer death in women age 25 to 49, and these young patients also have worse overall survival and increased risk of cancer coming back compared to older women, so it is important that we try to understand how the cancer develops and the measures that help prevent it," says the study's lead investigator, Karthik Ghosh, M.D. View Related 
Medical Edge Newspaper I hear a lot lately about smoking bans in cities or counties across the country. Is there any proof that these bans make a difference in the health of these communities? View Related
Mayo Clinic Health Letter -- December 2008 Mayo Clinic Health Letter is an eight-page monthly newsletter of reliable, accurate and practical information on today's health and medical news. View Related 
Mayo Clinic Women's HealthSource -- December 2008 Mayo Clinic Women's HealthSource is published monthly to help women enjoy healthier, more productive lives. Revenue from subscriptions is used to support medical research at Mayo Clinic. View Related 
Event: Rochester, Minn. Sporting state-of-the-art interactive media, the Center for Tobacco-Free Living presents a smart, modern way to help patients, family and health care professionals clear the air. View Related
Publication: The Journal of Cell Biology -- Nov. 17, 2008 
William C. Rupp, M.D., has been appointed CEO for the Florida campus effective Nov. 21, Mayo Clinic announced today. Rupp currently leads quality projects for Luther Midelfort, part of Mayo Health System, as well as Mayo Clinic. 
The Gail model calculates probabilities that a woman will develop invasive breast cancer during the next five years, and by age 90. "We found that, for the group of women with atypia, the model predicted significantly fewer invasive breast cancers than were actually observed," says Shane Pankratz, Ph.D., Mayo Clinic statistician and a lead investigator in the study. "We also observed that the model was not able to reliably identify the women who were actually at higher risk of developing breast cancer." View Abstract 
Study at Mayo Clinic confirms that CT Colonography could serve as screening option "We hope that this additional, less-invasive option for cancer screening will lead more people to get screened and will ultimately result in fewer deaths from colorectal cancer," says C. Daniel Johnson, M.D., principal investigator of the American College of Radiology Imaging Network (ACRIN) National CT Colonography Trial and chair of the Department of Radiology at Mayo Clinic in Arizona. View Related 
Mayo Clinic Women's HealthSource -- August 2008 Mayo Clinic Women's HealthSource is published monthly to help women enjoy healthier, more productive lives. Revenue from subscriptions is used to support medical research at Mayo Clinic. View Related 
Potentially, this vaccine could be used as a complementary tool with tamoxifen, a widely used estrogen therapy used as a temporary post-treatment approach to prevent the return of tumors. Breast cancer is second only to lung cancer as a killer of women. In 1998-2002, according to the American Cancer Society, 95 percent of new cases and 97 percent of deaths occurred in women 40 and older in the United States. However, early diagnosis and treatment have led to increasing survival rates in the last 25 years. There are more than two million breast cancer survivors in the United States today. Breast cancer is second only to lung cancer as a killer of women. In 1998-2002, according to the American Cancer Society, 95 percent of new cases and 97 percent of deaths occurred in women 40 and older in the United States. However, early diagnosis and treatment have led to increasing survival rates in the last 25 years. There are more than two million breast cancer survivors in the United States today. View Related 
Mayo Clinic Women's HealthSource -- July 2008 Mayo Clinic Women's HealthSource is published monthly to help women enjoy healthier, more productive lives. Revenue from subscriptions is used to support medical research at Mayo Clinic. View Related
Mayo Clinic Health Letter - June 2008 Mayo Clinic Health Letter is an eight-page monthly newsletter of reliable, accurate and practical information on today's health and medical news. View Related 
Medical Edge Newspaper I am 52. I had a total hysterectomy and cervix removal at age 38. Do I still need to get a pelvic exam and Pap smear? I get a 50/50 answer from peers and medical personnel. Which is it and why? View Related 
Medical Edge Newspaper What do I need to know about sunscreen? And is it okay to use on my kids? View Related 
Mayo Clinic Women's HealthSource -- April 2008 Mayo Clinic Women's HealthSource is published monthly to help women enjoy healthier, more productive lives. Revenue from subscriptions is used to support medical research at Mayo Clinic. View Related
Mayo Clinic Health Letter -- April 2008 Mayo Clinic Health Letter is an eight-page monthly newsletter of reliable, accurate and practical information on today's health and medical news. View Related
Mayo Clinic Women's HealthSource -- April 2008 Mayo Clinic Women's HealthSource is published monthly to help women enjoy healthier, more productive lives. Revenue from subscriptions is used to support medical research at Mayo Clinic. View Related
What if you could prevent Barrett's esophagus or stop its progression to esophageal cancer? And, while you were working on that, what if you could develop therapies that replace the standard treatment with a much less debilitating treatment than removal of the esophagus? View Related 
CT colonography, also known as virtual colonoscopy, underwent rigorous studies at Mayo Clinic for more than 10 years, while the stool DNA test was conceived and developed by Mayo Clinic researchers. View Related
Agreement strengthens relationship and spawns new scientific collaborations "TGen takes seriously our commitment to work toward helping patients with cancer and other disorders. This announcement is another mechanism allowing TGen and Mayo faculty to work bi-directionally in a more seamless fashion," said Jeffrey Trent, Ph.D., TGen's president and scientific director. View Related 
Using two different endoscopes together is better than using one to stage lung cancer, and is also much more precise and less invasive than the surgical method now most commonly used. "Both scopes together found more malignant lymph nodes than did the use of a single endoscope," says the study's lead investigator, Michael Wallace, M.D., M.P.H., Professor of Medicine at Mayo Clinic, Jacksonville, Fla. "Doing both procedures at once takes little time, requires only a mild sedative, and patients go home the same day." View Abstract
Sound waves may help early detection of heart failure caused by Trastuzumab "Breast cancer is the second most common form of cancer in women, and the leading cause of death," says Bijoy K. Khandheria, M.D., chair, Mayo Clinic Cardiovascular Services, researcher and co-investigator of the study. "Anticancer drugs like Trastuzumab have substantial benefits, but in some patients the anticancer drug cross-reacts with the heart muscle. Therefore, methods to detect and halt heart muscle damage is therefore urgently required." View Abstract
Discovery's Edge "When we examined human breast tissue we were blown away by how dramatic and obvious the centrosome abnormalities were in the tumors," says Jeffrey Salisbury, Ph.D. "And that was literally on day one." View Related 
Study's authors recruit patients for a clinical trail, another step in this ongoing research "We are now quite convinced that in most patients with pancreatic cancer the diabetes is caused by the cancer and not the other way around," says Suresh Chari, M.D., a Mayo Clinic gastroenterologist and the study's lead author. "Our next step is to identify a biomarker for pancreatic cancer-induced diabetes in order to screen patients with new-onset diabetes for early pancreatic cancer and provide surgical treatment as quickly as possible." View Abstract
Mayo Clinic Women's HealthSource -- January 2008 Mayo Clinic Women's HealthSource is published monthly to help women enjoy healthier, more productive lives. Revenue from subscriptions is used to support medical research at Mayo Clinic. View Related 
Medical Edge Television Every day up to two-thousand women have hysterectomies. Many of these women also choose to have their ovaries taken out at the same time to remove their risk of ovarian cancer. But for younger women who are not at high risk for ovarian cancer, doctors at Mayo Clinic are saying, "not so fast." Two studies show that keeping your ovaries until after menopause may protect you from memory problems and Parkinson's disease. 
Up to 30 percent of patients with colon and rectal cancer may develop a bowel obstruction View Related 
Medical Edge Radio For information on tobacco research and cessation treatment at Mayo Clinic, visit the Nicotine Dependence Center Web site at http://ndc.mayo.edu. Read Script 
Radiology researchers at Mayo Clinic have invented a diagnostic imaging tool with remarkable capabilities. It's called Magnetic Resonance Elastography or MRE. MRE can measure elasticity - detecting abnormal hardening of liver tissue - sparing some patients the need for a biopsy and allowing physicians to begin intervention aimed at treating their disease before it progresses to cause irreversible damage. View Related 
Mayo Clinic Cancer Center had researchers from many disciplines presenting more than 60 oral abstracts and dozens of posters, also educational sessions and other special events throughout the 2007 ASCO program, June 1-5. View Related 
The National Institutes of Health chose Mayo Clinic as one of the first 12 institutions to receive Clinical and Translational Science Awards (CTSA) in October 2006. "There are two objects in medical education: to heal the sick and advance the science." - Dr. Charles H. Mayo 
Yuan-Ping Pang, Ph.D. established the Computer-Aided Molecular Design Laboratory (CAMDL) to learn more about how biological systems function and to establish models that could lead to new treatments for infectious diseases and cancer. View Related 
Osteoporosis was not even considered a disease before Mayo Clinic's 1980s groundbreaking epidemiology studies. Funded by a $1.2 million per year NIH Program Project grant, the osteoporosis research team is also taking their research to the genetic and molecular levels to study the physiology of bone metabolism in an aging population. Their studies investigate the TGF-beta-Inducible Early Gene (TIEG) gene's role in bone and skeletal disorders such as osteoporosis and breast cancer metastasis to the bone. View Related 
Publication: Mayo Clinic Proceedings -- April 2007 Critical to the clinical management of a patient with malignant melanoma is an understanding of its natural history. As with most malignant disorders, prognosis is highly dependent on the clinical stage (extent of tumor burden) at the time of diagnosis. The patient’s clinical stage at diagnosis dictates selection of therapy. We review the state of the art in melanoma staging, prognosis, and therapy. View Related 
Publication: Journal of Clinical Oncology -- Apr. 1, 2007 Results of a Prospective Phase III North Central Cancer Treatment Group Clinical Trial View Related 
Publication: Journal of Supportive Oncology -- March 2007 North Central Cancer Treatment Group in conjunction with Mayo Clinic Cancer Center View Related 
Publication: Mayo Clinic Proceedings -- March 2007 Mammography added little information to the initial patient evaluation. Breast cancer may be suspected by the presence of a dominant mass. Gynecomastia can be predicted on the basis of the patient's symptoms or preexisting condition. Patients with suspicious findings on examination warrant appropriate clinical management regardless of mammographic findings. Mammography in men may be of benefit only for image guidance of percutaneous biopsy of a suspicious mass. View Related 
Publication: Mayo Clinic Proceedings -- March 2007 In the first part of this 2-part review, we discuss epidemiology, risk factors, screening, prevention, and diagnosis of malignant melanoma. Part 2 (which will appear in the April 2007 issue) will review melanoma staging, prognosis, and treatment. View Related 
Death Rates for Smokers Remain the Same Despite Early Diagnosis An international study looking at computed tomography (CT) to screen current or former smokers for lung cancer found that the screening did not reduce death. Researchers from Mayo Clinic Cancer Center, along with the Instituto Tumori, Milan, Italy; and Memorial Sloan-Kettering and Moffitt Cancer Centers collaborated to report the findings, which are published in the Mar. 7, 2007, issue of the Journal of the American Medical Association (JAMA). View Related 
Publication: Journal of Clinical Oncology -- Jan. 20, 2007 North Central Cancer Treatment Group View Related 
Publication: Mayo Clinic Proceedings -- Dec. 2006 Optimism was associated with a higher QOL in survivors of thyroid cancer compared with survivors of head and neck cancer. After adjusting for age, sex, and disease stage, optimism was not associated with QOL for survivors of head and neck cancer. Optimism was more associated with the mental rather than physical QOL subscales. 
You're at the doctor's office and he or she tells you there's a tiny spot in your lung. It could be cancer. To find out, your options have been to wait and see if it grows or go to surgery for a biopsy. Now there's another option. Medical Edge Television
Custom-fitting a Drug for a Child with Leukemia Some 20 years ago, Mayo Clinic researcher Richard Weinshilboum, M.D., and colleagues made a groundbreaking discovery: They determined why a dose of a drug that could produce astonishing cures in a lethal childhood cancer sometimes also could produce side effects that killed children. The reason behind this strikingly individual response to a drug was found in the genes. With this profound insight into the role that a patient's genetic make-up plays in how the patient responds to a drug, the new field of pharmacogenomic medicine was born. It continues to grow today—Mayo Clinic research leading the way discovering new treatment applications that range from depression, to breast cancer, to chemical dependency. View Related 
Publication: Cancer -- Oct. 15, 2006 The key to long-range improvement in cancer morbidity and mortality in American Indian/Alaska Native communities lies in building infrastructure to support strong partnerships that enable culturally appropriate, community-based participatory research. View Related
The Clinical Research Training Program provides a formal education in all aspects of clinical research, including grant-writing, legal and ethical issues, statistics, epidemiology and study design and protocols. "I realized how exciting research can be, and how exciting it is to advance the science." Jon Ebbert, M.D. View Related 
Publication: Journal of Clinical Oncology -- Aug. 1, 2006 A companion study to the National Cancer Institute of Canada Clinical Trials Group study MA.17 View Related 
Medical Edge Television Doctors at Mayo Clinic did a study to find out if giving women information before they have a mammogram makes a difference in their experience. 
Medical Edge Television One in eight. Those are the odds that your mom, sister, wife or friend has of getting breast cancer in her lifetime. The risk goes way up if you have one of two known breast cancer genes. 
Medical Edge Television Occasional heartburn is usually nothing to worry about. But if heartburn hits two or more times a week, you may be at risk of developing a condition called Barrett's esophagus that increases your risk of cancer. 
Publication: Journal of Clinical Oncology -- June 20, 2006 North Central Cancer Treatment Group clinical trial View Related
In helping young investigators, Mayo Clinic again is connecting all the dots -- leading back to the same point, the same mission, ongoing and yet unchanged for over a century: the needs of the patient come first. New, young investigators are critical to biomedical research. Their fresh ideas, innovativeness, and enthusiasm are necessary for scientific progress. Yet the steps from a junior research position toward a self-sufficient laboratory can be difficult. Mayo Clinic is dedicated to fostering future, investigators. Here we look at two of them and what Mayo is doing to help. View Related
Publication: Mayo Clinic Proceedings -- June 2006 The results suggest that providing women scheduled for screening mammograms with physician-approved educational material before their appointment significantly increases knowledge about screening mammography, risks and benefits, and possible follow-up. View Related 
In scientific literature, epidemiologic studies have linked reduced rates of certain cancers to cultures in Asia where green tea is a popular drink. Legend has it that the Chinese Emperor Shen Nung discovered tea around 2737 B.C.E. He was known as the Divine Healer, and that title is almost all one needs to know about why legends, right or wrong, persist. Green tea has come down through the ages, trailing behind it mythic tales of health benefits from "cheering the heart" to reducing inflammation, from improving bladder function to treating tumors. View Related 
Renal cell carcinoma is one of most dangerous forms of kidney cancer. An interdisciplinary team of Mayo Clinic investigators and Mayo's Comprehensive Cancer Center are pursuing improved treatments by pooling data and expertise with support from Florida. "With this approach, we can halt the disease and begin to cure kidney cancer." John Copland, M.D. View Related
Medical Edge Television Ten years ago, 48,000 women -- mothers, wives, sisters -- died every year from breast cancer. Today, that number has dropped to 40,000. But it's still too high. That's why many women who are at high risk of getting breast cancer choose genetic testing. 
Publication: Journal of Clinical Oncology -- Dec. 20, 2005 Results of a pooled analysis from the North Central Cancer Treatment Group View Related
Publication: Journal of Clinical Oncology -- Dec. 1, 2005 Individual patient data from 20,898 patients on 18 randomized trials: North Central Cancer Treatment Group View Related
Publication: Journal of Clinical Oncology -- June 15, 2004 North Central Cancer Treatment Group with National Cancer Institute of Canada View Related 
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