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Patient Stories

  • RNA sequencing identifies DNA changes that caused genetic abnormalities.
  • Pharmacogenomic testing provided insight into why certain medications didn't work for Nicole.
  • In Karen’s life-threatening situation, pharmacogenomic testing provided answers that applied to her care and helped family members find answers to their own health-related questions.
  • Applied pharmacogenomics resolves patient's lifelong anxiety and depression.
  • Microbiome transplant clears antibiotic-resistant intestinal infection.
  • Genome sequencing reveals rare gene mutation.
  • Sequencing uncovers genetic makeup of aggressive tumor.
  • Whole-genome sequencing provides diagnosis for rare neurological disorder.
  • Obscure symptoms mapped to rare pediatric disorder.
  • Individualized Medicine and The Diagnostic Journey

Personalized Medicine Concepts

  • The Biomarker Discovery Program captures genetic information from cells and analyzes it, searching for genetic patterns to help physicians make more precise diagnoses and prescribe more effective, individualized treatments.
  • The Microbiome Program explores the genetic code of the body's microorganisms, using the latest techniques to profile an individual's microbiome to detect, prevent and diagnose infections and other diseases.
  • The Pharmacogenomics Program investigates how variations in genes affect response to medications, thereby using a patient's genetic profile to predict a drug's efficacy, guide dosage and improve patient safety.
  • Genomic sequencing is a process for analyzing a sample of DNA taken from your blood. In the lab, technicians extract DNA and prepare it for sequencing.
  • The Clinomics Program quickly moves discoveries from the research lab to the clinical setting, with practical, cost-efficient genomic tests for diagnosing and treating patients.
  • The Epigenomics Program investigates the role of the epigenome, examines which factors act on individual genes, and how certain changes in the epigenome affect our health.

Personalized Medicine 101

  • Personalizing care, preventing disease
  • Living better, living longer

Center for Individualized Medicine Programs

  • George Vasmatzis, Ph.D., co-director, Biomarker Discovery Program
  • Matthew J. Ferber, Ph.D., and Eric D. Wieben, Ph.D., co-directors, Clinomics Program
  • Tamas Ordog, M.D., director, Epigenomics Program
  • Heidi Nelson, M.D., director, Microbiome Program
  • Richard Weinshilboum, M.D., director, Pharmacogenomics Program
  • Richard Sharp, Ph.D., director, Bioethics Program
  • Jean-Pierre A. Kocher, Ph.D., director, Bioinformatics Program
  • James R. Cerhan, M.D., Ph.D., co-director, Biorepositories Program
  • James D. Buntrock, director, Information Technology Program
  • Eric D. Wieben, Ph.D., director, Medical Genome Facility