All current and past graduate / postdoc students

• Fernado Reyers, Houston, TX (September 1987 - May 1988). Molecular cloning of phenylalanine hydroxylase gene to knock out the gene in mouse embryonic stem cells.
• Fernado Reyers, Summer undergraduate student, Houston, TX (June 1989 - September 1989). Molecular cloning of alpha 1-antitrypsin gene to knock out the gene in mouse embryonic stem cells.
• David Teeple, SURF student, University of Arizona, Tucson, AZ (May - August 1997). Expression of mutated cystic fibrosis transmembrane conductance regulator protein in baby hamster kidney cells.
• Jey-Hsin Chen, Rotation student of M.D. and Ph.D. program, Mayo Clinic College of Medicine, Rochester MN. (October - November 1997).Molecular cloning of cystic fibrosis transmembrane conductance regulator gene. He is a resident in Boston.
• Vivek Mittal, SURF student, Boston University, Boston, MA (May - August 1998). Expression of mutated multidrug resistance-associated protein in baby hamster kidney cells. He is a graduate student in the University of Washington.
• Paul M. Magtibay, M.D. resident rotation, Mayo Clinic Scottsdale, Scottsdale, AZ (March-July 1998). Cell culture (of multidrug-resistant cells). He is a surgeon.
• Dominic Jezierski, SURF student, University of Arizona, Tucson, AZ (May - August 1999). Purification of multidrug resistance-associated protein.
• Kevin Wu, SURF student, University of Southern California CA (July - August, 2002). Insertion of an epitope (HA epitope) into an extra-cellular loop of cystic fibrosis transmembrane conductance regulator. He is a medical school student.
• Aaron Goldberg, UBRP student, University of Arizona, Tucson, AZ (May - August 2003). Insertion of the mutated multidrug resistance associated protein into baccular virus expression system. He is an undergraduate student.
• Jenny Ahn, SURF student, Massachusetts Institute of Technology, Cambridge MA (June - August, 2003). Make mutations in the nucleotide binding domains of multidrug resistance associated protein. She is an undergraduate student.
• Doriane Trompier, Graduate student of the Institut de Biologie et Chimie des Proteines, Lyon, France. (February to April, 2001). The project was flavonoids binding to the multidrug resistance protein MRP1 and reversion of multidrug resistance caused by over-expression of MRP1. The research article “Multiple flavonoid-binding sites within multidrug resistance protein MRP1” is published in CMLS Cellular and Molecular Life Sciences 60, p2164-2177.
• Doriane Trompier, Graduate student of the Institut de Biologie et Chimie des Proteines, Lyon, France. (February - April, 2002). The project was molecular mechanism of the hypersensitivity to the multidrug resistance modulator verapamil in the MRP1-overexpressing cells. The research article “Verapamil and its derivative trigger apoptosis through glutathione extrusion by multidrug resistance protein MRP1” has been submitted to Cancer Research. Doriane Trompier is a postdoctoral fellow in Dr. Chimini’s laboratory in France.
• Zhenhua Huang, Graduate student of the Institute of Biophysics, Chinese Academy of Sciences, Beijing, China. (October, 2000 to present). The project is floppase activity of the purified multidrug resistance protein MRP1. The research article “Flourescent modified phosphatidylcholine floppase activity of reconstituted multidrug resistance-associated protein MRP1” has been accepted by Biochemica et Biophysica Acta. Zhenhua Huang has received his Ph.D. degree.
• Runying Yang, Postdoctoral fellow (October, 2001 to present). Mechanism of ATP-dependent anti-cancer drug transport by multidrug resistance associated protein. The article “ATP binding to the first nucleotide binding domain of MRP1 plays a regulatory role at low nucleotide concentration whereas ATP hydrolysis at the second plays a dominant role in ATP dependent LTC4 transport” has been published in J. Biological Chemistry.
• Qing Zhao, Postdoctoral fellow (June, 2003 - October, 2006). The mechanism of ATP induced conformational change of multidrug resistance associated protein. She is a research associate now.