Genetics of Ovarian Cancer - Jeremy Chien

Overview

The long-term goals of Dr. Chien's research program are to advance the understanding of ovarian carcinogenesis through integrated cancer genomics, genetics and proteomics and to translate these advances into clinical applications for early detection, diagnosis, prognosis and treatment of ovarian cancer.

Dr. Chien’s lab takes a systematic, integrative approach using multiple methodologies. Next-generation sequencing, functional genomics, cancer genetics and affinity-based proteomics are being pursued to characterize alterations in cancer genomes and biological pathways associated with critical steps in ovarian carcinogenesis — namely, malignant transformation, metastasis and resistance to chemotherapy.

Dr. Chien is an assistant professor of laboratory medicine and pathology in the Division of Experimental Pathology. He is an active member of the Mayo Clinic Cancer Center and Women’s Cancer Program, and receives funding from the National Institutes of Health, the Department of Defense, the Minnesota Ovarian Cancer Alliance, Mayo Clinic and the Andersen Foundation.