The mission of the Clinical Enteric Neuroscience Translational and Epidemiological Research (C.E.N.T.E.R.) Program is to become the premier epidemiology, clinical, and translational research center for clinical enteric neurosciences in the world. Additionally, the mission is to mentor and educate clinician investigators in the field of clinical enteric neurosciences.
The Activities of CENTER span from population-based research that utilizes the extensive resources of the Rochester Epidemiology Project, to clinical physiology, pharmacodynamics, diagnostics and trials in motility and functional gastrointestinal disorders.
The group is part of Mayo's Enteric Neuroscience Program, and a major initiative involves collaboration with basic scientists to establish translational research, including phenotype-genotype association studies, and pharmacogenomics.Read more
1. Understand the molecular and physiological mechanisms involved in gastrointestinal motor function in health and disease.
2. Understand the mechanisms that underlie gastrointestinal motor and sensory nerve function by integrating basic science and clinical research programs.
3. Develop and validate diagnostic tools to evaluate motor and sensory disorders of the gut.
4. Develop and test new treatment options for patients with gastrointestinal motility disorders including irritable bowel syndrome, non-ulcer dyspepsia, pseudo-obstruction, gastroparesis, constipation, and pelvic floor dysfunction.
5. Educate gastroenterology trainees, surgical trainees and postdoctoral fellows in the field of enteric sciences.
6. Educate patients, practicing physicians, and investigators on gastrointestinal motility disorders.
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