Cell PerfusionThis text is replaced by the Flash movie. The relationship between a mechanosensitive calcium channel (BLUE), BK (large conductance, calcium activated potassium channel, GREEN), and the cell contractile state. As perfusion mechanically stimulates the MS Ca2+ channel, calcium begins to enter the cell. Calcium concentration increases (indicated by red color), the cell contracts and BK channels activate. This allows K+ to leave the cell, hyperpolarizing the cell, and leads to cell relaxation. |
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