Role of Prostacyclin in Forearm Vasodilation in Patients with Essential Hypertension
IRB #: 854-05
Endothelial dysfunction has been demonstrated in patients with essential hypertension. Prostacyclin (PGI2) and nitric oxide are both endothelial derived substances important in regulation of normal vascular function. Using venous occlusion plethysmography, the purpose of this study is to evaluate the contribution of endothelial derived nitric oxide to prostacyclin mediated dilation in patients with endothelial dysfunction.
© 2013 Mayo Foundation for Medical Education and Research. All rights reserved.