Selected Publications
See a complete list of Dr. Miller's publications on PubMed
- Dong M, Lam PCH, Pinon DI, Hosohata K, Sexton PM, Abagyan R, Miller LJ. Molecular basis of secretin docking to its intact receptor using photolabile probes distributed throughout the pharmacophore. J Biol Chem. 2011 286:23888-23899. PMID: 21566140
- Miller LJ, Chen Q, Lam PCH, Pinon DI, Sexton PM, Abagyan R, Dong M. Refinement of glucagon-like peptide 1 docking to its intact receptor using mid-region photolabile probes and molecular modeling. J Biol Chem. 2011 286:15895-15907. PMID: 21454562
- Dong M, Le A, Te JA, Pinon DI, Bordner AJ, Miller LJ. Importance of each residue within secretin on receptor binding and biological activity. Biochemistry. 2011 50:2983-2993. PMID: 21388146
- Chen Q, Pinon DI, Miller LJ, Dong M. Spatial approximations between residues 6 and 12 in the amino-terminal region of glucagon-like peptide 1 and its receptor. A region critical for biological activity. J Biol Chem. 2010 285:24508-24518. PMID: 20529866
- Harikumar KG, Akgun E, Portoghese PS, Miller LJ. Modulation of cell surface expression of nonactivated cholecystokinin receptors using bivalent ligand-induced internalization. J Med Chem. 2010 53:2836-2842. PMID: 20235611
- Dong M, Lam PCH, Pinon DI, Orry A, Sexton PM, Abagyan R, Miller LJ. Secretin occupies a single protomer of the homodimeric secretin receptor complex: Insights from photoaffinity labeling studies using dual sites of covalent attachment. J Biol Chem. 2010 285:9919-9931. PMID: 20100828
- Harikumar KG, Simms J, Christopoulos G, Sexton PM, Miller LJ. Molecular basis of association of receptor activity-modifying protein 3 with the family B G protein-coupled secretin receptor. Biochemistry. 2009 48:11773-11785. PMID: 19886671
- Chen Q, Pinon DI, Miller LJ, Dong M. Molecular basis of glucagon-like peptide 1 docking to its intact receptor studied with carboxyl-terminal photolabile probes. J Biol Chem. 2009 284:34135-34144. PMID: 19815559
- Dong M, Cox RF, Miller LJ. Juxtamembranous region of the amino terminus of the family B G protein-coupled calcitonin receptor plays a critical role in small-molecule agonist action. J Biol Chem. 2009 284:21839-21847. PMID: 19447889
- Gao F, Harikumar KG, Dong M, Lam PCH, Sexton PM, Christopoulos A, Bordner A, Abagyan R, Miller LJ. Functional importance of a structurally distinct homodimeric complex of the family B G protein-coupled secretin receptor. Mol Pharmacol. 2009 76:264-274. PMID: 19429716
- Dong M, Lam PCH, Pinon DI, Abagyan R, Miller LJ. Elucidation of the molecular basis of cholecystokinin docking to its receptor with site-specific photoaffinity labeling through peptide residues 28 and 31 and molecular modeling. Biochemistry. 2009 48:5303-5312. PMID: 19441839
- Akgun E, Korner M, Gao F, Harikumar KG, Waser B, Reubi JC, Portoghese PS, Miller LJ. Synthesis and in vitro characterization of radioiodinatable benzodiazepines selective for type 1 and type 2 cholecystokinin receptors. J Med Chem. 2009 52:2138-2147. PMID: 19271701
- Harikumar KG, Gao F, Pinon DI, Miller LJ. Use of multidimensional fluorescence resonance energy transfer to establish the orientation of cholecystokinin docked at the type A cholecystokinin receptor. Biochemistry. 2008 47:9574-9581. PMID: 18700727
- Dong M, Lam PCH, Pinon DI, Sexton PM, Abagyan R, Miller LJ. Spatial approximation between secretin residue five and the third extracellular loop of its receptor provides new insight into the molecular basis of natural agonist binding. Mol Pharmacol. 2008 74:413-422. PMID: 18467541
- Dong M, Gao F, Pinon DI, Miller LJ. Insights into the structural basis of endogenous agonist activation of family B G protein-coupled receptors. Mol Endocrinol. 2008 22:1489-1499. PMID: 18372345
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