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RESEARCH GRANTS

ACTIVE

Principal Investigator

Xenogeneic Bioartifical Liver. (DK 56733)

08/2006 - 06/2009

Principal Investigator

Human Hepatocyte Culture on Synthetic Nanofiber ECM.

01/2007 - 12/2008

Principal Investigator

An Improved Bioartificial Liver for Extended Therapy.

07/2007 - 06/2009

COMPLETED

National Research Service Award: Immunology Training Grant. Funded by University of Minnesota Medical School. (CA09024-15)

01/1989 - 01/1991

Principal Investigator

Noninvasive measurement of brain glutamine by MR spectroscopy during acute hepatic failure. Funded by Mayo Foundation Scholarship.

01/1996 - 01/1997

Principal Investigator

Glycine Cytoprotection of Hepatocytes in a Bioartificial LIver. Funded by Mayo Foundation Internal Funding.

01/1997 - 01/1998

Principal Investigator

A Phase II/III, Multi-Center, Randomized, Controlled, Parallel Group Study of the HepatAssist Liver Assist System (LAS) Compared to Standard ICV Care in Patients with Acute Hepatic Failure and Hepatic Encephalopathy. Funded by CIRCE Biomedical. (Circe 1)

04/1997 - 07/2000

Principal Investigator

Cell Processing Budget for Circe BAL Study. Funded by Replaced with Protocol Funding (Research Committee funding).

10/1997 - 09/2000

Principal Investigator

Apoptosis and Necrosis of Hepatocytes in a Bioartificial Liver. Funded by Mayo Foundation.

01/1998 - 01/2000

Principal Investigator

An industry-sponsored, Phase II/III clinical study of the HepatAssist ®Liver Assist System for the treatment of acute liver failure. Funded by Circe Biomedical/Mayo Foundation.

01/1998 - 01/2001

Principal Investigator

Immune Response to a Xenogeneic Bioartificial Liver. Funded by ASTS Roche Presidential Travel Award.

01/2000

Principal Investigator

Roche Laboratories Presidential Travel Award. Funded by American Society of Transplant Surgeons.

07/2000 - 06/2001

Co-Investigator

Investigation of Tissue Level Expression and Secretion of Matrix Metalloproteinase 2 and 9 (Gelatinases) in a Porcine Polytetrafluoroethylene Graft Model of Venous Stenoses. Funded by Cardiovascular and Interventional Radiology Research and Educational Foundation. (CIRREF #1)

10/2000 - 03/2003

Principal Investigator

Immunogenicity of a Xenogeneic Bioartifical Liver. Funded by National Institute of Diabetes and Digestive and Kidney Diseases. (DK 56733)

04/1999 - 03/2004

PATENTS

Title

Patent number

Date issued

Spheroid Reservoir Bioartificial Liver

US 7160719

Bioreactor Device with Application as a Bioartificial Liver

US 5605835

02/25/1997


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