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Overview

The Division of Pediatric Hematology Oncology has research programs at all three levels: clinical, translational and basic science. Special areas of basic science research include research on leukemia cell signaling, mechanisms of brain tumor development, mechanisms of cell death pathways. Special clinical areas of research interest include but are not limited to sarcoma clinical trials, novel conditioning regimens for stem cell transplantation, and novel ways of decreasing inhibitor levels in patients with hemophilia. We are members of the Children's Oncology Group, the only cooperative group in the US for childhood cancer. Ninety per cent of our eligible patients are entered onto available clinical trials. We also have access to a variety of new drugs to treat recurrent tumors.

Our goal is ultimately to be able to bring even more of "the bench to the bedside" as we strive to improve the cure rate of childhood cancer.

Photo of Carola Arndt A., M.D.
  • Division Chair
"Pediatric oncology has made great strides in the past 50 years, with 75% of pediatric cancer patients being cured. I believe the key to curing the more refractory malignancies lies in unlocking the pathways to development of tumors so that they can be targeted for disruption and arrest of tumor growth."