Loss of brain function is arguably the most dreaded consequence of getting old. We propose to test the hypothesis that restoration of youthful levels of mechano growth factor (MGF) will arrest the decline in adult neurogenesis that is linked to loss of brain function in old individuals. We will take advantage of an inducible gene expression system that utilizes control elements from the lac operon of E. coli to induce or repress transgene expression in the mouse. We will ask two questions: 1)...

learn more

A postdoctoral position is available immediately in the Division of Hematology Research, Mayo Clinic Rochester. The fellow will join a highly interactive and collaborative research team that focuses on translational research in B cell malignancies. Current studies are specifically focused on (i) the role of TNF family members on the survival and progression of B cell lymphomas, (ii) the study of signaling pathways involved in B cell transformation, and (iii) characterization of genetic alterati...

learn more

The Pulmonary Cell Biology laboratory has an opening for a full time Post Doctoral Research Fellow in lung cellular physiology. The laboratory is generally focused on the mechanisms underlying normal function of the airway and pulmonary vasculature, and the pathophysiological mechanisms of disease (e.g. asthma, bronchopulmonary dysplasia, pulmonary hypertension). The research is conducted by a multidisciplinary group of scientists and physicians with strong emphasis on cellular imaging (fluo...

learn more

The Cardiovascular Molecular Imaging laboratory has an opening for a full time Post Doctoral Research Fellow. The main objective of the study is to elucidate the mechanism that regulates stem cell engraftment and survival in the myocardium, using state-of-the-art molecular imaging. We are seeking candidates who are interested in conducting and leading experimental studies that will cross the bridge from cell to rodent animal models. The successful candidate should be independent and creative, ...

learn more

The Vaccine Research Group at Mayo Clinic Rochester seeks a postdoctoral fellow to join a highly successful research team to study the genetics of immune responses to vaccines and research related to Biodefense vaccines. Projects include studies on smallpox, measles, rubella, influenza and other viral vaccines. Requirements for the position include 1) a Ph.D. and/or M.D. degree with significant past laboratory research experience, 2) a keen interest in vaccine and Biodefense research. Individ...

learn more

A postdoctoral position is available to study the neurobiology of alcohol use disorders and addictive behaviors. The successful applicant will investigate adenosine and glutamate signaling in neuron-glial interactions and/or neruobehavioral pharmacology of alcoholism using rodent models. Qualifications for the position include a Ph.D. degree with 0-3 years postdoctoral experience in molecular biology, neurobiology, rodent behaviors, or molecular pharmacology. Candidates who are highly self-mo...

learn more

A one-year training/fellowship (the Kurtz Fellowship), which is renewable for year two, is available for 2010 for a highly-motivated trainee or fellow wishing to study the biology and/or treatment of multiple myeloma. The candidate will join a comprehensive, world-leading multiple myeloma program at Mayo Clinic which offers a broad range of opportunities for clinical and laboratory-based research. The candidate should hold an M.D. degree and should have a strong commitment to pursuing a career...

learn more

The Division of Biomedical Statistics and Informatics (BSI) in the Department of Health Sciences Research, Mayo Clinic (http://www.mayo.edu) in Rochester, Minnesota (www.macc-rochester.com) is seeking a bioinformatics Research Associate (RA) with a Ph.D. in bioinformatics or biology/biochemistry with significant bioinformatics experience. The RA in this position will collaborate with Mayo researchers in studies conducted using genomics/proteomics/metabolomics as well as high throughput sequencin...

learn more

A Postdoctoral Research Fellow is sought by the Mayo Pharmacogenomics Research laboratory. This laboratory is associated with the Mayo-NIH Pharmacogenomics Research Network (PGRN), a nationwide network of research centers devoted to pharmacogenetic and pharmacogenomic research. Studies conducted include the use of high throughput resequencing of genes that might influence drug response, functional genomics, in depth mechanistic studies of the functional effects of DNA sequence variation and tran...

learn more

A newly funded R01 grant, located at Mayo Clinic Arizona ("Molecular Pathogenesis of Multiple Myeloma") requires a motivated postdoctoral scientist to study the functional consequences of the activation of critical pathways we have identified frequently mutated (e.g., NFKB, histone methylation) in human and murine myeloma. Relevant studies from the Bergsagel lab include Keats et al, Cancer Cell 2007 12(2) 131-44 and Chesi et al, Cancer Cell 2008 13(2) 167-80....

learn more

Mayo Clinic (http://www.mayo.edu) in Rochester, Minnesota (www.macc-rochester.com) is seeking a postdoctoral candidate with a Ph.D. in statistics or biostatistics and training in statistical genetics. Mayo Clinic is a world-class health care organization, with cutting-edge genetic research programs. The Division of Biomedical Statistics and Informatics (BSI) includes more than 280 experts in biostatistics, bioinformatics, and clinical informatics. Our scientists work collaboratively with basic a...

learn more

The Laboratory for Renovascular Research has an opening for a full time Post Doctoral Research Fellow in physiological imaging. The research is conducted in multidisciplinary group of scientists with strong emphasis on MR and CT imaging of physiological processes and tissue characteristics, and involves development and application of functional MRI techniques in the kidney and heart. We are seeking candidates who are interested in conducting and leading experimental studies in large animal...

learn more

Mayo Clinic in Rochester, Minnesota is seeking postdoc candidates in methodology development and annotation of DNA sequence data from high throughput, next-generation sequencing machines (e.g. Roche/454, Illumina/Solexa, ABI SOLiD). The Division of Biomedical Statistics and Informatics (BSI) includes more than 280 experts in biostatistics, bioinformatics, and clinical informatics. Our scientists work collaboratively with basic and clinical researchers, providing analytical and interpretative...

learn more

Newly funded R01 grant ("Antibody Neutralization of Therapeutic Viruses") requires a motivated postdoctoral scientist interested in joining the group of Stephen Russell to develop viable strategies to increase the efficiency of measles delivery to disseminated myeloma sites in measles-immune subjects. Experience in virology and/or immunology highly advantageous. Requirement: PhD. Salary will be determined by the successful candidate's experience. ...

learn more

Postdoctoral positions are available to study mechanisms of epigenetic inheritance and their impact on genome stability in yeast and/or mammalian cells. Relevant studies from my lab include Han et al, Science 2007; 351: 653-655 and Li et al Cell 2008; 134: 244-55. Please visit (http://ndc.mayo.edu/mayo/research/zhang_lab/) for more details about our current projects. Candidates who have solid background in molecular biology and biochemistry and are highly self-motivated in research are encourage...

learn more

NIH-funded post-doctoral position in vascular biology is available to study the coronary microcirculation and its impact on atherosclerosis progression. The overall objective of our research is the non-invasive detection of vulnerable plaque. Several diabetic and surgical animal models some of which have been developed in our laboratory and cardiac human tissue provide a unique opportunity to study and image atherosclerosis. The position will use new x-ray/CT imaging methodologies and conduct...

learn more

A postdoctoral research position is available immediately in the area of computational structural biology at the Mayo Clinic in Arizona. Current research interests include algorithm development for biomolecular simulations, docking, force field development, machine learning in structural bioinformatics, and applications of these techniques to drug discovery. More information is available at http://www.bordnerlab.org
The ideal candidate will have received a Ph.D. in Physics, Chemistry, o...

learn more

A position is available immediately on the NIH Training Program in Nephrology. MD and PhD candiates are encouraged to apply for a 1-2 year training program. Trainees can select among research areas in the division, including active programs in nephrolithiasis, bone and mineral metabolism, polycystic kidney disease, mechanisms of renal injury, hypertension, and others. ...

learn more