Postdoctoral Position - Division of Anesthesiology Research
Summary
Investigator: Y.S. Prakash,
MD, PhD Professor of Anesthesiology and Physiology
The Pulmonary Cell Biology laboratory has an opening for a full time Post Doctoral Research Fellow in lung cellular physiology.
The laboratory is generally focused on the mechanisms underlying normal function of the airway and pulmonary vasculature, and the pathophysiological mechanisms of disease (e.g. asthma, bronchopulmonary dysplasia, pulmonary hypertension). The research is conducted by a multidisciplinary group of scientists and physicians with strong emphasis on cellular imaging (fluorescence microscopy, real-time imaging of calcium and other signaling molecules, confocal microscopy), organ-bath and other techniques for studying tissue function, cell culture, transgenic animal models, biochemistry (Western blots, immunoprecipitation, ELISA) and molecular biology (laser capture microdissection, qRT-PCR). Experiments mainly deal with tissues such as airway smooth muscle, bronchial epithelium and pulmonary artery derived from humans as well as animal models. Disease models are developed in vivo or simulated in vitro using immunological and other interventions.
We are seeking candidates who are interested in conducting and leading experimental studies in cell and tissue systems and/or small animal models. The successful candidate will be heavily involved in one or two major projects tailored to his/her background and scientific interests. For example, projects could involve a) functional cell imaging (e.g. fluorescence measurement of calcium, sodium, nitric oxide, mitochondrial movement) and image and data analysis in the setting of disease; b) dissection of cellular signaling pathways induced by airway inflammation; c) cell-cell interactions in modulation of bronchoconstriction and bronchodilation.
The successful candidate should be independent and creative, able to work as part of a multi-disciplinary group with physicians, scientists and engineers at all stages (investigators, graduate students, fellows, technicians), and should have strong written and communication skills. Experience with cellular imaging, a strong interest in lung biology, and demonstrated ability to publish manuscripts in peer-reviewed journals will be preferred.
This position is funded by an existing NIH grant for a minimum period of 2 years.
Qualifications:
* MD or PhD with strong background in physiology, biomedical engineering or related field. Background in biochemistry/molecular biology with proven efforts to develop skills in imaging will also be considered very positively.
* Scientific interest in and experience with lung cells and their physiology or pathophysiology
* Experience in cellular imaging, image processing and similar areas is preferred, but not mandatory. Lack of experience in imaging compensated by extensive biochemistry/molecular biology and a keen interest in learning imaging is encouraged.
* Candidate must be adept at the use of computers, scientific and professional development software.(Microsoft products, Endnote etc).
How to apply
Applications, including curriculum vitae and bibliography, summary of past accomplishments, and the names and email addresses of three references, should be sent to:
Y S Prakash MD, PhD
Email:prakash.ys@mayo.edu
Phone Number: 507 538 9869
Ad ID Number
360
Mayo Clinic is a not-for-profit organization that integrates research with clinical practices and education in multi-campus environment. Mayo offers an attractive benefit package. Salary will be determined by the successful candidate's experience.
Mayo Clinic is an affirmative action and equal opportunity employer and educator.
