Multiple sclerosis (MS) affects nearly 400,000 patients in the United States. It is the most common disabling disease of young adults. The disease results in significant disability in over 50% of patients. Current treatments are suboptimal. Therefore, the major focus of the theme is to advance our clinical and scientific knowledge of MS and related diseases in order to design novel therapeutics to help every patient.
The vision of the Multiple Sclerosis Laboratory is to develop new avenues of treatment for patients with disorders of the CNS with inflammatory and demyelinating pathology. We strongly believe that it is through basic science research and careful clinical investigation that these disorders will be ultimately cured, and hopefully, prevented. We are committed to the mission of advancing our knowledge both through the scientific process by publishing our work into top tier peer-reviewed journals, as well as by passing our knowledge on to our graduate students, medical students, residents, and fellows.
The Multiple Sclerosis Laboratory acknowledges the generosity of our current benefactors.
Eugene and Marcia Applebaum:
The Applebaums are long time patients and benefactors of Mayo Clinic. Mr. Applebaum is the president of Arbor Investments Group. A pharmacist, he founded Arbor Drugs in 1974, and it grew to be the eighth largest drugstore chain in the nation. In 1998 it was acquired by Rhode Island-based CVS, a "Fortune 100" organization and the nation's largest drugstore chain.
The research funds provided by Mr. and Mrs. Eugene Applebaum over the last four years have been used to develop human antibodies that can induce the repair of myelin on axons within demyelinated lesions. Two human monoclonal antibodies have been identified and are in the final stages of preparation as therapeutic reagents for clinical trials.
In most cities around the world, the directions and destination would be familiar-a journey on mass transit to a spacious, inviting hotel. But if you're at Mayo Clinic in Rochester, Minn., those words have quite a different meaning. The Hilton Building at Mayo represents a dynamic partnership. It links two "household names," which share a commitment to service and international goodwill in their respective fields.
Born in an adobe dwelling in San Antonio, Conrad Hilton was one of seven children. Working in the family's general store, he acquired skills that made him an international business leader and statesman. The Hilton Building at Mayo Rochester is a prime example of his generous philanthropy. Like the Mayo brothers, Mr. Hilton was committed to educating future leaders in his chosen profession. He established the Conrad N. Hilton College of Hotel and Restaurant Management in 1969 at the University of Houston. When forming his estate plan, Mr. Hilton showed the same personal concern and business savvy that made his hotels successful. After providing for loved ones, he passed his fortune-and the authority to use it- to the Conrad N. Hilton Foundation.
The Hilton Foundation has made a generous award to the Multiple Sclerosis Laboratory in its project entitled A Recombinant Human Monoclonal Antibody for Promotion of Myelin Repair in Multiple Sclerosis, which mark the first attempt to use a recombinant human antibody to promote remyelination and hopefully will relieve human suffering by repairing CNS damage in patients with MS.
Ms. Peterson is the niece of John K. Hansen, founder of the Winnebago Company, a name synonymous with recreational travel. Ms. Peterson's father had a diverse career that included key positions at Winnebago. Ms. Peterson majored in philosophy at St. Olaf College in Northfield, Minn. Her father's career provided an extended residence in South America, and she previously owned a leather business in St. Thomas and another store in North Carolina. She now resides in Rochester.
Ms. Peterson's late parents, G. Wallace and Dorothea Peterson, provided two scholarships at Mayo Medical School. Ms. Peterson has met many of the scholars and supports her parents' commitment to medical education and, in addition, provides leadership support for Mayo’s research in multiple sclerosis.
© 2013 Mayo Foundation for Medical Education and Research. All rights reserved.