Brief Description: The compositeLD package computes composite measures of Linkage Disequilibrium, their variances and covariances, and statistical tests, for all pairs of alleles from two loci when linkage phase is unkown. ================================================================= Installation procedures for compositeLD Intallation procedures in this file are for setting up a 'local library' for a user. If a large group of users plan to use the same library, then install on a system-wide 'library' location designated by a system administrator. -------------------------------------------------------------- S-PLUS Installation The compositeLD S-PLUS functions are written for S-PLUS version 7.0.6 To install the software for local use in S-PLUS, move compositeLD_x.y.z_S.tar.gz to your installation directory and follow the series of commands: 1) gunzip compositeLD_x.y.z_S.tar.gz 2) tar -xvf compositeLD_x.y.z_S.tar 3) cd compositeLD 4) cd src 5) Splus CHAPTER -m 6) Splus make -f makefile.compLD Note that the installation for S-PLUS 8 will be more like the R installation below. ====================================================================== R Installation The compositeLD package is not available for distribution through any R websites. To install, downloading the README.compositeLD file with compositeLD_x.y.z.tar.gz and execute the following command with the local "INSTALL LIBRARY DIR PATH" correctly specified. R CMD INSTALL -l /INSTALL LIBRARY DIR PATH/ compositeLD_x.y.z.tar.gz Additional details on R may be found on the R project website (http://www.r-project.org). ====================================================================== User Documenation: There is a demo file located in the /compositeLD/demo/ directory that shows a simple example for using compositeLD. We warn that compositeLD has computing limits (run-time and memory limits) for when the number of alleles is high, which is roughly 10 alleles for each locus.