Brief Description: Tests for the fit of genotype frequencies to Hardy-Weinberg Equilibrium proportions. Different statistical tests are provided, as well as an option to evaluate statistical significance by simulations. ================================================================= Installation procedures for hwe Intallation procedures in this file are for setting up a 'local library' for a user. If a large group of users plan to use the same library, then install on a system-wide 'library' location designated by a system administrator. -------------------------------------------------------------- S-PLUS Installation The hwe S-PLUS functions are written for S-PLUS version 7.0.6 To install the software for local use in S-PLUS, move hwe_x.y.z_S.tar.gz to your installation directory and follow the series of commands: 1) gunzip hwe_x.y.z_S.tar.gz 2) tar -xvf hwe_x.y.z_S.tar 3) cd hwe/src 4) Splus CHAPTER -m 5) Splus make -f makefile.hwe Note that the package is not available as an R-like package for S-PLUS 8.0.1 or later. Follow the above instructions for installation to S-PLUS 8, but we recommend version 8.0.4 or later. ====================================================================== R Installation The hwe package is not available for distribution through any R websites. To install, download the README.hwe file with hwe_x.y.z.tar.gz and execute the following command with the local "INSTALL LIBRARY DIR PATH" correctly specified. R CMD INSTALL -l /INSTALL LIBRARY DIR PATH/ hwe_x.y.z.tar.gz Additional details on R may be found on the R project website (http://www.r-project.org). ====================================================================== User Documenation: Please find specific instructions in the help files for the hwe functions, for example by typing help(hwe) at the R or S-PLUS prompt.