Researcher Profile: Pirko, Istvan , MD

Istvan Pirko, M.D.

Location: Minnesota

Primary Appointment
Neurology

Clinical Profile

Summary

My research concentrates on animal models of clinically relevant MRI findings in multiple sclerosis (MS) and MS-related diseases.

Through our collaboration with the Nuclear Magnetic Resonance Core Facility at Mayo, we have access to a 7 Tesla and a 16.3 Tesla small-animal MRI system. We investigate the immunopathogenesis of (1) T1 black hole formation; (2) deep gray matter T2 hypointensity; (3) brain and spinal cord atrophy; and (4) fulminant/hemorrhagic demyelination in our novel mouse models.

In addition, we also plan to study the MRI and MRS signatures of remyelination, in collaboration with Moses Rodriguez, M.D. All the above models are unique to our laboratory and our collaborators. A key collaborator on these projects is Aaron J. Johnson, M.D. at the Waddell Center for Multiple Sclerosis, University of Cincinnati.

Several recent and upcoming publications summarize the key aspects of our research, as listed in my PubMed link.

Recent publications

See my publications

Education

Post-Grad – Semmelweiss University Medical School; Department of Biomedical Engineering
Technical University of Budapest, Hungary

Internship – Internal Medicine Preliminary Year
Medical College of Ohio, Toledo

Residency – Neurology residency
Medical College of Ohio, Toledo

Chief Resident – Neurology
Medical College of Ohio, Toledo

Fellowship – Neuroimmunology/MS fellowship
Mayo School of Graduate Medical Education, Rochester, MN

Fellowship – Experimental neuroimaging fellowship
Department of Neurology and Center for Imaging Research, University of Cincinnati

M.D. – Six-year medical program
University Medical School of Debrecen

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