Roshini S. Abraham, Ph.D.

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Photo of Roshini Abraham S., Ph.D.
07:14:45:468
Roshini S. Abraham, Ph.D.
Location: Minnesota
  • Primary Appointment
  • Laboratory Medicine and Pathology
  • Joint Appointment
  • Allergy and Immunology
  • Academic Rank
  • Associate Professor of Laboratory Med/Pathology
  • Associate Professor of Medicine
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Summary

The research interests of Roshini S. Abraham, Ph.D., include both clinical and translational aspects of cellular and molecular immunology in several areas of clinical laboratory diagnostics and mechanisms of disease pathogenesis.

Dr. Abraham's clinical research efforts are done in close collaboration with a number of interdisciplinary clinical groups and scientists at Mayo Clinic in allergy, immunology, hematology, rheumatology, pulmonary and critical care medicine, oncology, and the Transplant Center.

Focus areas

The three main focus areas of Dr. Abraham's research are:

  • Primary immunodeficiency, which are inherited (congenital) defects of the immune system
  • Assessment of immune competence, function and reconstitution in a variety of clinical contexts, particularly solid organ transplantation, hematopoietic stem cell transplantation, immunotherapy and cancer vaccines
  • Elucidating the requirements for immune reconstitution after hematopoietic stem cell or bone marrow transplant

Significance to patient care

Dr. Abraham's group is interested in developing state-of-the-art clinically robust laboratory methods to assess immune competence and reconstitution that can be used both in the diagnostic clinical setting and for standardized evaluation of immune function in clinical trials.

Additionally, her group is conducting studies exploring the role of inflammatory cytokines in the pathogenesis and temporal regulation of acute lung injury post-hematopoietic stem cell transplant (both allogeneic and autologous).

Recent publications

See a listing of my publications

Education

Clinical Post Doctoral Fellowship –
Division of Clinical Biochemistry & Immunology, Department of Laboratory Medicine and Pathology

Post Doctoral Fellowship –
Department of Immunology

Ph.D. – Immunology
National Institute of Immunology

MSc – Microbiology
Bangalore University

BSc – Chemistry and Biology
Jabalpur University




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