Researcher Profile: Babovic-Vuksanovic, Dusica , M.D.

Dusica Babovic-Vuksanovic, M.D.

Location: Minnesota

Primary Appointment
Medical Genetics
Joint Appointment
Pediatric and Adolescent Medicine
Administrative Appointment
Chair, Medical Genetics
Academic Rank
Associate Professor of Pediatrics
Associate Professor of Medical Genetics

Clinical Profile

Summary

Clinical Studies and Translational Research in the Area of Neurofibromatosis

Examples of Research Projects

Completed Protocols:

PI: A pilot, phase II, open-label clinical trial of pirfenidone (an antifibrotic agent) in adult patients with Neurofibromatosis type I and plexiform and paraspinal neurofibromas (PI). The study was coordinated through Mayo Cancer Center.

Co-PI: "Phase I Clinical trial of Pirfenidone in Childen and Adolescents with plexifom neurofibromas." Study was a part of multi-center clinical trial, coordinated by NCI.

Current Protocols:

Co-PI: "Phase II Clinical Trial of Pirfenidone in Children, Adolescents, and Young Adults with Neurofibtromatosis Type I and Progressive Plexiform Neurofibromas," coordinated by NCI, in collaboration with Childrens National Medical Center (PI Dr. Roger Packer).

Protocols in Development:

PI: "A Phase-2 Study of AZD2171 in Adult Patients with Neurofibromatosis Type I and Extensive Plexiform and Paraspinal Neurofibromas," coordinated by Cancer Therapy Evaluation Program (CTEP) and sponsored by AstraZeneca Pharmaceuticals; multicenter protocol with Mayo Clinic lead.

My research also involves several collaborative basic research studies in the field of neurofibromatosis, in conjuntion with Mayo Neuro-Oncology program, Mayo Radiology Department, and Mayo Neurosurgery Department.

My research interests include overgrowth syndromes, as well as various genetic syndromes and metabolic disorders.

Recent publications

See my publications

Education

Clinician Investigator Fellow
Mayo Clinic Rochester

Fellowship
Department of Medical Genetics, Mayo Clinic, Rochester, MN

Residency
Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN

Visiting Clinician
Department of Endocrinology, Royal Hospital for Sick Children

MMedSc – Basic Research. Thesis: "Diagnostic and prognostic value of limited joint mobility and skin changes in juvenile diabetics"
University of Sarajevo, Yugoslavia

Residency
Children's Hospital, University of Sarajevo, Yugoslavia

Research Fellowship
Institute of Hygiene and Protection of Human Environment, University of Sarajevo, Yugoslavia

M.D.
University of Sarajevo, Yugoslavia

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