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John C. Burnett, M.D.
 John C. Burnett, M.D.
Location:
Minnesota
SummaryCardiovascular endocrinology of heart failure and atherosclerosis The Cardiorenal Research Laboratory has pursued the broad area of cardiovascular endocrinology, with a focus on humoral mechanisms which link the heart, vascular wall and kidney in heart failure and atherosclerosis. Humoral systems of interest include the natriuretic peptides (AND, BNP, CNP, and DNP), endothelin, angiotensin II, aldosterone and adrenomedullin. Studies have also focused on defining such humoral systems as noninvasive markers for these disease processes as well as prognostic factors in predicting outcome. Work in the laboratory employs methodologies of integrative physiology, cell and molecular biology, biochemistry and human investigation. Research also focuses on strategies for CHF which include dual NEPI/ACS as well as therapies administering the natriuretic peptides, specifically BNP and ADM. A new area of investigation is the design and synthesis of unique chimeric (synthetic) peptides which possess novel mechanisms of action and have the potential for therapeutic action in heart failure and atherosclerosis. Recent publicationsEducation
Fellowship
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Clinical Cardiology
Research Fellowship
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NIH Research Fellow, Nephrology Research Laboratory
Residency
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Internal Medicine
Internship
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Internal Medicine
M.D.
Research Fellowship
B.S.
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Physiology
Other
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