John C. Burnett Jr., M.D.
John C. Burnett Jr., M.D., studies the endocrine role of the heart in cardiorenal homeostasis with a focus on the natriuretic peptides in heart failure, hypertension and myocardial infarction. The long-term goal is the engineering and clinical development of novel designer natriuretic peptides for the treatment of human cardiorenal disease, including the development of innovative natriuretic peptide-based diagnostics.
With continuous funding from the National Institutes of Health, Dr. Burnett and his team have developed three novel designer peptides currently in clinical trials targeting heart failure and resistant hypertension. From this work, seven patents have been awarded and three new biotechnology companies founded.
Significance to patient care
Dr. Burnett's research is of high clinical impact. Specifically, his research addresses the huge unmet need for new drugs and biomarkers for cardiorenal disease. Progress in these areas may truly lead to reducing the burden of human disease.
NIH Research Fellow, Nephrology Research Laboratory
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