Timothy R. DeGrado, Ph.D.
The research interests of Timothy R. DeGrado, Ph.D., are in uses of molecular imaging for research and clinical diagnostics.
Dr. DeGrado has specific interests in molecular imaging development for positron emission tomography (PET), single-photon emission computerized tomography (SPECT), optical imaging and magnetic resonance imaging, including radioisotope production, radiochemistry and radiopharmacology. Research has focused on receptor ligands and metabolizable small molecule radiotracers for cancer, neuronal and cardiovascular imaging.
Significance to patient care
Molecular imaging provides a noninvasive method to monitor the biochemistry in human diseases at the cellular level. Patient care is improved by having a clearer understanding of the biochemical status of the disease within each patient such that the best treatment options can be decided for an individual patient rather than making treatment decision based on group averages.
Novel molecular imaging targets will help focus the interest to a specific aspect of the disease that is predictive of patient outcome and sensitive to therapy response to provide early information on treatment effect.
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