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Gianrico Farrugia, M.D.
 Gianrico Farrugia, M.D.
Location:
Minnesota
SummaryGastrointestinal motility requires coordination between nerves, a specialized cell type called the interstitial Cell of Cajal, and smooth muscle cells. The research programs in the laboratory are aimed at understanding the regulation of gastrointestinal motility in health and disease. Our current projects include the study of: a) physiological and pathophysiological relevance of Ca2+ and Na+ mechanosensitive ion channels; b) ion channel regulation in gastrointestinal smooth muscle; c) the role of interstitial cells of Cajal in the regulation of gastrointestinal motility in health and in disease states; and, d) the role of carbon monoxide as a messenger molecule. The laboratory interacts closely with colleagues in the Department of Physiology and Biophysics, the Department of Pathology, the Department of Surgery and the department of Medicine especially cardiology. Techniques using in the laboratory include patch clamp techniques, muscle strip techniques, optical laser tweezers, laser capture micro-dissection, confocal microscopy, immunohistochemistry, single cell PCR and standard molecular biology techniques. Recent publicationsSee a listing of my publications Education
Fellowship
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Clinical Investigator Fellowship, Gastroenterology
Fellowship
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Research Fellowship, Physiology and Biophysics with Dr. J.H. Szurszewski and Dr. J.L. Rae (Gastrointestinal and Ophthalmologic Physiology)
Residency
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Internal Medicine
Internship
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Internal Medicine
Internship
M.D.
B.S.
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Biology, Physics and Chemistry
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