Zvonimir S. Katusic, M.D., Ph.D.
The human brain possesses unique blood vessels designed to maintain a constant supply of blood to highly perfused neuronal tissue. Impairment of brain blood flow causes strokes and plays a major role in the development of Alzheimer's disease.
Dr. Katusic's group has a long history of studying human cerebral blood vessels. Their studies are performed on experimental models of stroke and Alzheimer's disease.
Projects are focused on morphological, functional and biochemical characteristics of cerebral vasculature. In addition, experiments on isolated blood vessels enable Dr. Katusic's team to directly test vascular effects of novel drugs.
Dr. Katusic's research has been funded by the National Institutes of Health, American Heart Association, and a number of other funding agencies and organizations.
Significance to patient care
The recognition of endothelium in brain blood vessels as a major therapeutic target significantly advanced efforts to develop pharmacological therapies, as well as gene- and cell-based therapies.
Dr. Katusic's research will help to alleviate suffering and improve quality of life for patients with stroke and Alzheimer's disease.
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