Researcher Profile: McGregor, Christopher G, MB, FRCS

Christopher G. A. McGregor, M.D.

Location: Minnesota

Primary Appointment
Cardiovascular Surgery
Joint Appointment
Transplantation Surgery
Academic Rank
Professor of Surgery

Clinical Profile

Summary

Dr. Christopher McGregor graduated from the University of Glasgow Medical School in 1972. He is currently Professor of Surgery, Mayo Clinic College of Medicine and Consultant in Thoracic and Cardiovascular Surgery, Mayo Clinic and Saint Marys Hospital. Dr. McGregor is also the Director of the Mayo Clinic William J. von Liebig Transplant Center and a Mayo Graduate Faculty Member in Virology and Gene Therapy. He is a pioneer in the field of transplantation, having performed the first successful (one-year survival) lung transplant in Europe, the first successful (one-year survival) infant heart transplant in the UK, and the first combined heart-lung-liver transplant (one-year survival) in the US. Dr. McGregor is also on the Editorial Board of The Journal of Heart and Lung Transplantation, Journal of Translational Medicine and Current Cardiology Reviews.

Xenotransplantation. The principal focus in the preclinical xenotransplantation laboratory, which I direct, is optimization of immunosuppression following xenotransplantation with specific studies on the pathophysiology, diagnosis and treatment of humoral rejection. This program has the world's leading outcomes in cardiac xenotransplantation at the present time.

Mechanisms and prevention of chronic rejection of the heart following transplantation. The principal causes of death after the first three months following heart transplantation is accelerated transplant atherosclerosis. Studies of adenoviral-mediated cardiac gene therapy in modifying this process is ongoing. This work is supported by the National Institutes of Health.

Recent publications

See my publications on PubMed

Education

Fellowship – Cardiac Surgery
Stanford University

Fellowship – Cardiac and Cardiopulmonary Transplantation
Stanford University

Senior Registrar – Papworth Hospital, Cambridge, England
Department of Cardiothoracic Surgery, Papworth Hospital

Lecturer – Royal Infirmary, Edinburgh, Scotland
Department of Cardiac Surgery, Royal Infirmary

Registrar – Royal Hospital for Sick Children and Royal Infirmary, Glasgow, Scotland
Department of Cardiothoracic Surgery, Royal Infirmary

Residency – Surgery
Greater Glasgow Health Board

Residency – Pathology: Clinical and Research; Victoria Infirmary, Glasgow, Scotland
Royal Victoria Infirmary

Internship – Medicine & Surgery, Glasgow, Scotland
Royal Victoria Infirmary

Areas of Research
Xenotransplantation and Gene Therapy research

Academic Affiliations
Virology and Gene Therapy Program

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