Publications - Robert E . Wharen Jr., M.D.

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1. Nottmeier EW, Wharen RE, Patel NP. Iatrogenic intradural spinal arachnoid cyst as a complication of lumbar spine surgery. J Neurosurg Spine 2009 Sep; 11(3):344-6.
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2. Cheshire WP Jr, Wharen RE Jr. Trigeminal neuralgia in a patient with spontaneous intracranial hypotension. Headache 2009 May; 49(5):770-3.
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3. Cheshire W, Wharen RE. Trigeminal neuralgia in a patient with spontaneous intracranial hypotension. Headache Clinical Note 2009:1-4.
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4. York JE, Wharen RE, Bloomfield EL. Esophageal tear in a patient undergoing stereotactic brain biopsy under general anesthesia. J Anesth 2009; 23(3):432-5. Epub 2009 Aug 14.
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5. Obwegeser AA, Uitti RJ, Lucas JA, Witte RJ, Turk MF, Galiano K, Wharen RE. Correlation of outcome to neurosurgical lesions: confirmation of a new method using data after microelectrode-guided pallidotomy. Br J Neurosurg 2008 Oct; 22(5):654-62.
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6. Obwegeser AA, Uitti RJ, Lucas JA, Witte RJ, Turk MF, Galiano K, Wharen RE. Correlation of outcome to neurosurgical lesions: confirmation of a new method using data after microelectrode-guided pallidotomy. Br J Neurosurg 2008:1-9 Epub 2008 Jul.
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7. Sun FT, Morrell MJ, Wharen RE Jr. Responsive cortical stimulation for the treatment of epilepsy. Neurotherapeutics 2008 Jan; 5(1):68-74.
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8. Slowinski JL, Putzke JD, Uitti RJ, Lucas JA, Turk MF, Kall BA, Wharen RE. Unilateral deep brain stimulation of the subthalamic nucleus for Parkinson disease. J Neurosurg 2007 Apr; 106(4):626-32.
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9. Cheshire WP, Odell JA, Woodward TA, Wharen RE Jr. Cervical sympathetic neuralgia arising from a schwannoma. Headache 2007 Mar; 47(3):444-6.
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10. Cheshire WP, Odell JA, Woodward TA, Wharen RE. Cervical sympathetic neurlagia arising from a schwannoma. Headache: The Journal of Head and Face Pain 2007; 43(3):444-6.
11. Slowinski J, Stomal M, Reimer R, Deen HG, Pettit PD, Wharen RE. Video-laparoscopic assistance in cerebrospinal fluid shunting procedures. Neurol Neurochir Pol 2006 Sep-Oct; 40(5):455-6.
12. Yamamoto S, Steers JL, Wharen RE Jr, Eckman CB, Nguyen JH. Cerebrospinal fluid drainage and cranial decompression prolong survival in rats with fulminant hepatic failure. Transpl Int 2006 Aug; 19(8):675-82.
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13. Senol V, Soyuer F, Arman F, Ozturk A, et al. Non-AED/Non-Surgical Treatments (Hormonal, Ketogenic Diet, VNS, etc.)Adult. Epilepsia 2005 October; 46(8):222-226(5).
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14. Wharen RE Jr, Putzke JD, Uitti RJ. Deep brain stimulation lead fixation: a comparative study of the Navigus and Medtronic burr hole fixation device. Clin Neurol Neurosurg 2005 Aug; 107(5):393-5. Epub 2004 Dec 15.
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15. Putzke JD, Uitti RJ, Obwegeser AA, Wszolek ZK, Wharen RE. Bilateral thalamic deep brain stimulation: midline tremor control. J Neurol Neurosurg Psychiatry 2005 May; 76(5):684-90.
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16. Putzke JD, Wharen RE, Obwegeser AA, Wszolek ZK, Lucas JA, Turk MF, Uitti RJ. Thalamic deep brain stimulation for essential tremor: Recommendations for long-term outcome analysis. Can J Neurol Sci 2004 Aug; 31(3):333-42.
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17. McIver JI, Uitti RJ, Wharen RE. Treatment of essential tremor. Contemporary Neurosurgery 2004; 26(7).
18. Putzke JD, Wharen RE, Wszolek ZK, Turk MF, Strongosky AJ, Uitti RJ. Thalamic deep brain stimulation for tremor-predominant Parkinson's disease. Parkinsonism & Related Disorders 2003 Dec; 10(2):81-8.
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19. Deen HG, Birch BD, Wharen RE, Reimer R. Lateral mass screw-rod fixation of the cervical spine: a prospective clinical series with 1-year follow-up. Spine Journal 2003 Nov-Dec; 3(6):489-95.
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20. Deen HG, Pettit PD, Sevin BU, Wharen RE, Reimer R. Lumbar peritoneal shunting with video-laparoscopic assistance: A useful technique for the management of refractory postoperative lumbar CSF leaks. Surg Neurol 2003 Jun; 59(6):473-7.
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21. Slowinski J, Wharen RE, Uitti RJ, Wszolek ZK, Krygowska-Wajs A, Mrowka R. [Current therapies for parkinson's disease. Part II: surgical treatment] [Article in Polish] Neurol Neurochir Pol 2003 May-Jun; 37(3):677-86.
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22. Thomas CY, Chouinard M, Cox M, Parsons S, Stallings-Mann M, Garcia R, Jove R, Wharen R. Spontaneous activation and signaling by overexpressed epidermal growth factor receptors in glioblastoma cells. Int J Cancer 2003 Mar 10; 104(1):19-27.
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23. Smith AM, Adler CH, Crews D, Wharen RE, Laskowski ER, Barnes K, Bell CV, Pelz D, Brennan RD, Smith J, Sorenson MC, Kaufman KR. The 'Yips' in golf - A continuum between a focal dystonia and choking. Sports Med 2003; 33(1):13-31.
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24. Meschia JF, Brott TG, Kotsenas AL, Dickson DW, Wharen RE. Failure to wean from a ventilator caused by ANNA-1 seropositive paraneoplastic syndrome. Eur Neurol 2003; 50(2):112-4.
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25. Uitti RJ, Tsuboi Y, Pooley RA, Putzke JD, Turk MF, Wszolek ZK, Witte RJ, Wharen RE. Magnetic resonance imaging and deep brain stimulation. Neurosurgery 2002 Dec; 51(6):1423-8.
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26. Bratton RL, Brazis PW, Hellinger WC, Wharen RE, Broderick DF. Aspergillosis related to long-term nasal, corticosteroid use. Mayo Clin Proc 2002 Dec; 77(12):1353-7.
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27. Thomas C, Ely G, James CD, Jenkins R, Kastan M, Jedlicka A, Burger P, Wharen R. Glioblastoma-related gene mutations and over-expression of functional epidermal growth factor receptors in SKMG-3 glioma cells. Acta Neuropathol (Berl) 2001 Jun; 101(6):605-15.
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28. Obwegeser AA, Uitti RJ, Witte RJ, Lucas JA, Turk MF, Wharen RE Jr. Quantitative and qualitative outcome measures after thalamic deep brain stimulation to treat disabling tremors. Neurosurgery 2001 Feb; 48(2):274-81; discussion 281-4.
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29. Obwegeser AA, Uitti RJ, Turk MF, Wszolek UM, Flipse TR, Smallridge RC, Witte RJ, Wharen RE Jr. Simultaneous thalamic deep brain stimulation and implantable cardioverter-defibrillator. Mayo Clin Proc 2001 Jan; 76(1):87-9.
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30. Uitti RJ, Lucas JA, Obwegeser AA, Turk MF, Wharen RE. Pallidotomy and psychological outcomes. Journal of Neurosurgery 2001; 94:867-8.
31. Obwegeser AA, Uitti RJ, Lucas JA, Witte RJ, Turk MF, Wharen RE Jr. Predictors of neuropsychological outcome in patients following microelectrode-guided pallidotomy for Parkinson's disease. J Neurosurg 2000 Sep; 93(3):410-20.
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32. Lyons MK, Atkinson JL, Wharen RE, Deen HG, Zimmerman RS, Lemens SM. Surgical evaluation and management of lumbar synovial cysts: the Mayo Clinic experience. J Neurosurg 2000 Jul; 93(1 Suppl):53-7.
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33. Uitti RJ, Wharen RE, Duffy JR, Lucas JA, Schneider SL, Rippeth JD, Wszolek ZK, Obwegeser AA, Turk MF, Atkinson EJ. Unilateral pallidotomy for Parkinson's disease: speech, motor, and neuropsychological outcome measurements. Parkinsonism & Related Disorders 2000 Jul; 6(3):133-143.
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34. Obwegeser AA, Uitti RJ, Turk MF, Strongosky AJ, Wharen RE. Thalamic stimulation for the treatment of midline tremors in essential tremor patients. Neurology 2000 Jun 27; 54(12):2342-4.
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35. Brazis PW, Wharen RE, Czervionke LF, Witte RJ, Jones AD. Hemangioma of the mandibular branch of the trigeminal nerve in the Meckel cave presenting with facial pain and sixth nerve palsy. J Neuroophthalmol 2000 Mar; 20(1):14-6.
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36. Lucas JA, Rippeth JD, Uitti RJ, Shuster EA, Wharen RE. Neuropsychological functioning in a patient with essential tremor with and without bilateral VIM stimulation. Brain & Cognition 2000 Mar; 42(2):253-67.
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37. McLaughlin MP, Wharen RE, Thomas CY, Reimer R. The multidisciplinary management of brain metastases. Cancer Research, Therapy & Control 1999; 9(3-4):273-79.
38. Reimer R, Wharen RE Jr, Pettit PD. Ventriculoperitoneal shunt placement with video-laparoscopic guidance. J Am Coll Surg 1998 Dec; 187(6):637-9.
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39. Uitti RJ, Wharen RE Jr, Turk MF. Efficacy of levodopa therapy on motor function after posteroventral pallidotomy for Parkinson's disease. Neurology 1998 Dec; 51(6):1755-7.
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40. Uitti RJ, Wharen RE Jr, Turk MF, Lucas JA, Finton MJ, Graff-Radford NR, Boylan KB, Goerss SJ, Kall BA, Adler CH, Caviness JN, Atkinson EJ. Unilateral pallidotomy for Parkinson's disease: comparison of outcome in younger versus elderly patients. Neurology 1997 Oct; 49(4):1072-7.
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41. Clendenen SR, Harper JV, Wharen RE Jr, Guarderas JC. Anaphylactic reaction after cisatracurium. Anesthesiology 1997 Sep; 87(3):690-2.
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42. Lucas JA, Finton MJ, Uitti RJ, Wharen RE. Neurocognitive functioning prolonged survival in Parkinson's disease. Parkinsonism & Related Disorders 1997; 3:159-65.
43. Deen HG, Ebersold MJ, Harner SG, Beatty CW, Marion MS, Wharen RE, Green JD, Quast L. Conservative management of acoustic neuroma: an outcome study. Neurosurgery 1996 Aug; 39(2):260-4; discussion 264-6.
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44. Green JD, Wharen RE, Reimer R. Tumors of the Cerebellopontine Angle. Jacksonville Medicine 1996; 47:70-2.
45. Wharen RW, Reimer R. Degenerative lumbar stenosis treated by decompression without fusion. Techniques in Neurosurgery 1996; 2:212-22.
46. Green JD, Wharen RE, Reimer R. Lateral Approaches to the Skull Base. Jacksonville Medicine 1996; 47:67-9.
47. Brazis PW, Menke DM, McLeish WM, Broderick DF, Cheshire WP, Wharen RE Jr, Tiemann M. Angiocentric T-cell lymphoma presenting with multiple cranial nerve palsies and retrobulbar optic neuropathy. J Neuroophthalmol 1995 Sep; 15(3):152-7.
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48. Schild SE, Wharen RE Jr, Menke DM, Folger WN, Colon-Otero G. Primary lymphoma of the spinal cord. Mayo Clin Proc 1995 Mar; 70(3):256-60.
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49. Deen HG Jr, Zimmerman RS, Lyons MK, Wharen RE Jr, Reimer R. Analysis of early failures after lumbar decompressive laminectomy for spinal stenosis. Mayo Clin Proc 1995 Jan; 70(1):33-6.
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50. Wharen RE, Reimer R. Degenerative lumbar stenosis treated by decompression laminectomy: is a concomitant fusion ever necessary. Perspective in Neurosurgery 1994; 5(2):41-59.
51. Schievink WI, Wharen RE Jr, Reimer R, Pettit PD, Seiler JC, Shine TS. Laparoscopic placement of ventriculoperitoneal shunts: preliminary report. Mayo Clin Proc 1993 Nov; 68(11):1064-6.
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52. Miles JM, Cattalini M, Sharbrough FW, Wold LE, Wharen RE Jr, Gerich JE, Haymond MW. Metabolic and neurologic effects of an intravenous medium-chain triglyceride emulsion. JPEN: Journal of Parenteral & Enteral Nutrition 1991 Jan-Feb; 15(1):37-41.
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53. Wharen RE Jr, So S, Anderson RE, Laws ER Jr. Hematoporphyrin derivative photocytotoxicity of human glioblastoma in cell culture. Neurosurgery 1986 Oct; 19(4):495-501.
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54. Wharen RE Jr, Anderson RE, Sundt TM Jr. The ND: YAG laser in neurosurgery. Part 2. Clinical studies: and adjunctive measure for hemostasis in resection of arteriovenous malformations. J Neurosurg 1984 Mar; 60:540-547.
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55. Wharen RE Jr, Anderson RE, Scheithauer B, Sundt TM Jr. The Nd:YAG laser in neurosurgery. Part 1. Laboratory investigations: dose-related biological response of neural tissue. J Neurosurg 1984 Mar; 60(3):531-9.
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56. Anderson RE, Wharen RE Jr, Jones CA, Laws ER Jr. Parameters of hematoporphyrin derivative tumor cell killing efficiency: decomposition of hematoporphyrin derivative at high power densities. Progress in Clinical & Biological Research 1984; 170:483-500.
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57. Agrez MV, Wharen RE Jr, Anderson RE, Laws ER Jr, Ilstrup DM, Cortese DA, Shorter RG, Lieber MM. Hematoporphyrin derivative: quantitative uptake in dimethylhydrazine-induced murine colorectal carcinoma. J Surg Oncol 1983 Nov; 24(3):173-6.
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58. Wharen RE Jr, Anderson RE, Laws ER Jr. Quantitation of hematoporphyrin derivative in human gliomas, experimental central nervous system tumors, and normal tissues. Neurosurgery 1983 Apr; 12(4):446-50.
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59. Wharen RE Jr, Scheithauer BW, Laws ER Jr. Thrombosed arteriovenous malformations of the brain. An important entity in the differential diagnosis of intractable focal seizure disorders. J Neurosurg 1982 Oct; 57(4):520-6.
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60. Coudran TA, Dunn PE, Seballos HL, Wharen RE, Sandburg LL, Law JH. Preparation of homogenous Juvenile Hormone specific esterase from the haemolymph of the tobacco hornworm, Manduca Sexta. Insect Biochem 1981; 11:453-61.