Publications - Michael D . Jensen, M.D.

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1. Mundi MS, Karpyak MV, Koutsari C, Votruba SB, O'Brien PC, Jensen MD. Body Fat Distribution, Adipocyte Size, and Metabolic Characteristics of Nondiabetic Adults. J Clin Endocrinol Metab 2009 Nov 04. [Epub ahead of print]
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2. Koutsari C, Ali AH, Nair KS, Rizza RA, O'Brien P, Khosla S, Jensen MD. Fatty acid metabolism in the elderly: effects of dehydroepiandrosterone and testosterone replacement in hormonally deficient men and women. J Clin Endocrinol Metab 2009 Sep; 94(9):3414-23. Epub 2009 Jun 30.
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3. Jensen MD, Bajnarek J, Lee SY, Nielsen S, Koutsari C. Relationship between postabsorptive respiratory exchange ratio and plasma free fatty acid concentrations. J Lipid Res 2009 Sep; 50(9):1863-9.
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4. Hou XG, Moser S, Sarr MG, Thompson GB, Que FG, Jensen MD. Visceral and subcutaneous adipose tissue diacylglycerol acyltransferase activity in humans. Obesity (Silver Spring) 2009 Jun; 17(6):1129-34. Epub 2009 Feb 05.
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5. Henderson GC, Dhatariya K, Ford GC, Klaus KA, Basu R, Rizza RA, Jensen MD, Khosla S, O'Brien P, Nair KS. Higher muscle protein synthesis in women than men across the lifespan, and failure of androgen administration to amend age-related decrements. FASEB J 2009 Feb; 23(2):631-41. Epub 2008 Sep 30.
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6. Jensen MD. Role of body fat distribution and the metabolic complications of obesity. J Clin Endocrinol Metab 2008 Nov; 93(11 Suppl 1):S57-63.
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7. Koutsari C, Snozek CL, Jensen MD. Plasma NEFA storage in adipose tissue in the postprandial state: sex-related and regional differences. Diabetologia 2008 Nov; 51(11):2041-8. Epub 2008 Aug 19.
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8. Santosa S, Hensrud DD, Votruba SB, Jensen MD. The influence of sex and obesity phenotype on meal fatty acid metabolism before and after weight loss. Am J Clin Nutr 2008 Oct; 88(4):1134-41.
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9. Santosa S, Jensen MD. Why are we shaped differently, and why does it matter? Am J Physiol Endocrinol Metab 2008 Sep; 295(3):E531-5. Epub 2008 May 20.
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10. Allison DB, Downey M, Atkinson RL, Billington CJ, Bray GA, Eckel RH, Finkelstein EA, Jensen MD, Tremblay A. Obesity as a disease: a white paper on evidence and arguments commissioned by the Council of the Obesity Society. Obesity (Silver Spring) 2008 Jun; 16(6):1161-77. Epub 2008 May 08.
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11. Koutsari C, Dumesic DA, Patterson BW, Votruba SB, Jensen MD. Plasma free fatty acid storage in subcutaneous and visceral adipose tissue in postabsorptive women. Diabetes 2008 May; 57(5):1186-94. Epub 2008 Feb 19.
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12. Tchoukalova YD, Koutsari C, Karpyak MV, Votruba SB, Wendland E, Jensen MD. Subcutaneous adipocyte size and body fat distribution. Am J Clin Nutr 2008 Jan; 87(1):56-63.
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13. Guo Z, Jensen MD, Xu JZ, Zhou LZ, Persson XMT, Balagopal P, Yarasheski K. Oxidation of intracellular and extracellular fatty acids in skeletal muscle. Eur J Lipid Sci Technol 2008 Jan; 110(1):5-15.
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14. Potretzke A, Warren M, Schmitz K, Gottsacker T, Jensen MD. Relationship between insulin sensitivity and long-term weight change in adults. Submitted for publication 2008.
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15. Lee S, Jensen MD. Adipogenic risk factor differences between Korean and Caucasian adults – potential risk of plasma free fatty acid and adiponectin. Metabolism ( 2008; in press).
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16. Romero-Corral A, Sierra-Johnson J, Marek O, Gami A, Davison D, Sert-Kuniyoshi F, Pusalavidyasager S, Huyber C, Votruba S, Jensen M, Somers V. Modest fat gain causes endothelial dysfunction in healthy humans. Submitted for publication 2008.
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17. Tchoukalova Y, Koutsari C, Votruba S, Jensen M. Committed preadipocyte availability is reduced in leg fat in men compared with women. Submitted for publication 2008.
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18. Gormsen LC, Nellemann B, Sorensen LP, Jensen MD, Christiansen JS, Nielsen S. Impact of body composition on very-low-density-lipoprotein-triglycerides kinetics. Am J Physiol Endocrinol Metab ( 2008; in press).
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19. Koutsari C, Basu R, Rizza RA, Basu R, Nair KS, Khosla S, Jensen MD. Non-oxidative free fatty acid disposal is greater in women than men. Submitted for publication 2008.
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20. Votruba SB, Jensen MD. Insulin sensitivity does not predict upper body fat gain in response to overfeeding. Submitted for publication 2008.
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21. Buchwald H, Estok R, Fahrbach K, Banel D, Jensen MD, Pories W, Bantle J, Sledge I. Effects of Bariatric Surgery on Type 2 Diabetes: a Systematic Review and Meta-analysis. Am J Medicine ( 2008; in press).
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22. Votruba SB, Mattison RS, Dumesic DA, Koutsari C, Jensen MD. Meal fatty acid uptake in visceral fat in women. Diabetes 2007 Oct; 56(10):2589-97. Epub 2007 Jul 30.
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23. Jensen MD. Adipose tissue metabolism -- an aspect we should not neglect? Horm Metab Res 2007 Oct; 39(10):722-5.
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24. Bruns CM, Baum ST, Colman RJ, Dumesic DA, Eisner JR, Jensen MD, Whigham LD, Abbott DH. Prenatal androgen excess negatively impacts body fat distribution in a nonhuman primate model of polycystic ovary syndrome. Int J Obes (Lond) 2007 Oct; 31(10):1579-85. Epub 2007 May 01.
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25. Jensen MD. What is the potential role of cannabinoid-1 receptor blockade in glucose and lipid management? Am J Med 2007 Sep; 120(9 Suppl 1):25-31.
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26. Schmitz KH, Hannan PJ, Stovitz SD, Bryan CJ, Warren M, Jensen MD. Strength training and adiposity in premenopausal women: Strong, Healthy, and Empowered study. Am J Clin Nutr 2007 Sep; 86(3):566-72.
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27. Romero-Corral A, Somers VK, Sierra-Johnson J, Jensen MD, Thomas RJ, Squires RW, Allison TG, Korinek J, Lopez-Jimenez F. Diagnostic performance of body mass index to detect obesity in patients with coronary artery disease. Eur Heart J 2007 Sep; 28(17):2087-93. Epub 2007 Jul 10.
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28. Jensen MD. What is the potential role of cannabinoid-1 receptor blockade in glucose and lipid management? Am J Med 2007 Sep; 120(9 Suppl 1):S25-31; discussion S31-2.
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29. Basu R, Dalla Man C, Campioni M, Basu A, Nair KS, Jensen MD, Khosla S, Klee G, Toffolo G, Cobelli C, Rizza RA. Effect of 2 years of testosterone replacement on insulin secretion, insulin action, glucose effectiveness, hepatic insulin clearance, and postprandial glucose turnover in elderly men. Diabetes Care 2007 Aug; 30(8):1972-8. Epub 2007 May 11.
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30. Basu R, Dalla Man C, Campioni M, Basu A, Nair KS, Jensen MD, Khosla S, Klee G, Toffolo G, Cobelli C, Rizza RA. Effect of 2 years of testosterone replacement on insulin secretion, insulin action, glucose effectiveness, hepatic insulin clearance, and postprandial glucose turnover in elderly men. Diabetes Care 2007 Aug; 30(8):1972-8. Epub 2007-05-11.
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31. Basu R, Man CD, Campioni M, Basu A, Nair KS, Jensen MD, Khosla S, Klee G, Toffolo G, Cobelli C, Rizza RA. Effect of 2 years of testosterone replacement on insulin secretion, insulin action, glucose effectiveness, hepatic insulin clearance, and postprandial glucose turnover in elderly men. Diabetes Care 2007 Aug; 30(8):1972-8.
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32. Vazquez Roque MI, Camilleri M, Clark MM, Tepoel DA, Jensen MD, Graszer KM, Kalsy SA, Burton DD, Baxter KL, Zinsmeister AR. Alteration of gastric functions and candidate genes associated with weight reduction in response to sibutramine. Clin Gastroenterol Hepatol 2007 Jul; 5(7):829-37.
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33. Shadid S, Kanaley JA, Sheehan MT, Jensen MD. Basal and insulin-regulated free fatty acid and glucose metabolism in humans. Am J Physiol Endocrinol Metab 2007 Jun; 292(6):E1770-4. Epub 2007 Feb 13.
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34. Votruba SB, Jensen MD. Sex differences in abdominal, gluteal, and thigh LPL activity. Am J Physiol Endocrinol Metab 2007 Jun; 292(6):E1823-8. Epub 2007 Feb 20.
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35. Michailidou Z, Jensen MD, Dumesic DA, Chapman KE, Seckl JR, Walker BR, Morton NM. Omental 11beta-hydroxysteroid dehydrogenase 1 correlates with fat cell size independently of obesity. Obesity (Silver Spring) 2007 May; 15(5):1155-63.
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36. Shadid S, Koutsari C, Jensen MD. Direct free fatty acid uptake into human adipocytes in vivo: relation to body fat distribution. Diabetes 2007 May; 56(5):1369-75.
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37. Clark MM, Hanna BK, Mai JL, Graszer KM, Krochta JG, McAlpine DE, Reading S, Abu-Lebdeh HS, Jensen MD, Sarr MG. Sexual abuse survivors and psychiatric hospitalization after bariatric surgery. Obes Surg 2007 Apr; 17(4):465-9.
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38. Basu A, Jensen MD, McCann F, Nandy D, Mukhopadhyay D, McConnell JP, Rizza RA. Lack of an effect of pioglitazone or glipizide on lipoprotein-associated phospholipase A2 in type 2 diabetes. Endocr Pract 2007 Mar-Apr; 13(2):147-52.
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39. Basu R, Man CD, Campioni M, Basu A, Nair KS, Jensen MD, Khosla S, Klee G, Toffolo G, Cobelli C, Rizza RA. Two years of treatment with dehydroepiandrosterone does not improve insulin secretion, insulin action, or postprandial glucose turnover in elderly men or women. Diabetes 2007 Mar; 56(3):753-66.
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40. Krag MB, Gormsen LC, Guo Z, Christiansen JS, Jensen MD, Nielsen S, Jorgensen JOL. Growth hormone-induced insulin resistance is associated with increased intramyocellular triglyceride content but unaltered VLDL-triglyceride kinetics. Am J Physiol Endocrinol Metab 2007 Mar; 292(3):E920-7.
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41. Jensen MD, Nielsen S. Insulin dose response analysis of free fatty acid kinetics. Metabolism 2007 Jan; 56(1):68-76.
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42. Tchoukalova Y, Koutsari C, Jensen M. Committed subcutaneous preadipocytes are reduced in human obesity. Diabetologia 2007 Jan; 50(1):151-7. Epub 2006 Nov 10.
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43. Tchkonia T, Lenburg M, Thomou T, Giorgadze N, Frampton G, Pirtskhalava T, Cartwright A, Cartwright M, Flanagan J, Karagiannides I, Gerry N, Forse RA, Tchoukalova Y, Jensen MD, Pothoulakis C, Kirkland JL. Identification of depot-specific human fat cell progenitors through distinct expression profiles and developmental gene patterns. Am J Physiol Endocrinol Metab 2007 Jan; 292(1):E298-307. Epub 2006 Sep 19.
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44. Votruba SB, Jensen MD. Regional fat deposition as a factor in FFA metabolism. Annu Rev Nutr 2007; 27:149-63.
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45. Vazquez Roque MI, Camilleri M, Stephens DA, Jensen MD, Burton DD, Baxter KL, Zinsmeister AR. Gastric sensorimotor functions and hormone profile in normal weight, overweight, and obese people. Gastroenterology 2006 Dec; 131(6):1717-24. Epub 2006 Oct 15.
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46. Guo Z, Zhou L, Jensen MD. Acute hyperinsulinemia inhibits intramyocellular triglyceride synthesis in high-fat-fed obese rats. J Lipid Res 2006 Dec; 47(12):2640-6. Epub 2006 Sep 11.
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47. Scheen AJ, Finer N, Hollander P, Jensen MD, Van Gaal LF, RIO-Diabetes Study Group. Efficacy and tolerability of rimonabant in overweight or obese patients with type 2 diabetes: a randomised controlled study. Lancet 2006 Nov 11; 368(9548):1660-72.
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48. Scheen AJ, Finer N, Hollander P, Jensen MD, Van Goal LF. Efficacy and tolerability of rimonabant in overweight or obese patients with type 2 diabetes: a randomised controlled study. Lancet 2006 Nov 11; 368(9548):1660-72.
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49. Votruba SB, Jensen MD. Sex-specific differences in leg fat uptake are revealed with a high-fat meal. Am J Physiol Endocrinol Metab 2006 Nov; 291(5):E1115-23. Epub 2006 Jun 27.
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50. Nair KS, Rizza RA, O'Brien P, Dhatariya K, Short KR, Nehra A, Vittone JL, Klee GG, Basu A, Basu R, Cobelli C, Toffolo G, Dalla Man C, Tindall DJ, Melton LJ 3rd, Smith GE, Khosla S, Jensen MD. DHEA in elderly women and DHEA or testosterone in elderly men. N Engl J Med 2006 Oct 19; 355(16):1647-59.
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51. Shadid S, LaForge R, Otvos JD, Jensen MD. Treatment of obesity with diet/exercise versus pioglitazone has distinct effects on lipoprotein particle size. Atherosclerosis 2006 Oct; 188(2):370-6. Epub 2005 Nov 28.
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52. Collazo-Clavell ML, Clark MM, McAlpine DE, Jensen MD. Assessment and preparation of patients for bariatric surgery. Mayo Clin Proc 2006 Oct; 81(10 Suppl):S11-7.
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53. Gormsen LC, Jensen MD, Schmitz O, Moller N, Christiansen JS, Nielsen S. Energy expenditure, insulin, and VLDL-triglyceride production in humans. J Lipid Res 2006 Oct; 47(10):2325-32. Epub 2006 Jul 18.
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54. Shadid S, Stehouwer CD, Jensen MD. Diet/Exercise versus pioglitazone: effects of insulin sensitization with decreasing or increasing fat mass on adipokines and inflammatory markers. J Clin Endocrinol Metab 2006 Sep; 91(9):3418-25. Epub 2006 Jun 27.
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55. Moller N, Jensen MD, Rizza RA, Andrews JC, Nair KS. Renal amino acid, fat and glucose metabolism in type 1 diabetic and non-diabetic humans: effects of acute insulin withdrawal. Diabetologia 2006 Aug; 49(8):1901-8. Epub 2006 May 23.
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56. Koutsari C, Jensen MD. Thematic review series: patient-oriented research. Free fatty acid metabolism in human obesity. J Lipid Res 2006 Aug; 47(8):1643-50. Epub 2006 May 09.
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57. Jensen MD. Potential role of new therapies in modifying cardiovascular risk in overweight patients with metabolic risk factors. Obesity (Silver Spring) 2006 Jun; 14 Suppl 3:143S-149S.
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58. Jensen MD. Adipose tissue as an endocrine organ: implications of its distribution on free fatty acid metabolism. Eur Heart J Suppl 2006 May; 8(B):B13-9.
59. Harris AM, Jensen MD, Levine JA. Weekly changes in basal metabolic rate with eight weeks of overfeeding. Obesity (Silver Spring) 2006 Apr; 14(4):690-5.
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60. Basu A, Jensen MD, McCann F, Mukhopadhyay D, Joyner MJ, Rizza RA. Effects of pioglitazone versus glipizide on body fat distribution, body water content, and hemodynamics in type 2 diabetes. Diabetes Care 2006 Mar; 29(3):510-4.
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61. Jensen MD. Is visceral fat involved in the pathogenesis of the metabolic syndrome? Human model. Obesity (Silver Spring) 2006 Feb; 14 Suppl 1:20S-24S.
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62. Gormsen LC, Jensen MD, Nielsen S. Measuring VLDL-triglyceride turnover in humans using ex vivo-prepared VLDL tracer. J Lipid Res 2006 Jan; 47(1):99-106. Epub 2005 Oct 18.
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63. Shadid S, Jensen MD. Pioglitazone increases non-esterified fatty acid clearance in upper body obesity. Diabetologia 2006 Jan; 49(1):149-57. Epub 2005 Dec 02.
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64. Guo Z, Yarasheski K, Jensen MD. High-precision isotopic analysis of palmitoylcarnitine by liquid chromatography/electrospray ionization ion-trap tandem mass spectrometry. Rapid Commun Mass Spectrom 2006; 20(22):3361-6.
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65. Buchwald H, Consensus Conference Panel. Bariatric surgery for morbid obesity: health implications for patients, health professionals, and third-party payers. J Am Coll Surg 2005 Apr; 200(4):593-604.
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66. Smith AM, Lopez-Jimenez F, McMahon MM, Thomas RJ, Wellik MA, Jensen MD, Hensrud DD. Action on obesity: Report of a Mayo Clinic National Summit. Mayo Clin Proc 2005 Apr; 80(4):527-32.
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67. Uranga AP, Levine J, Jensen M. Isotope tracer measures of meal fatty acid metabolism: reproducibility and effects of the menstrual cycle. American Journal of Physiology - Endocrinology & Metabolism 2005 Mar; 288(3):E547-55.
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68. Levine JA, Lanningham-Foster LM, McCrady SK, Krizan AC, Olson LR, Kane PH, Jensen MD, Clark MM. Interindividual variation in posture allocation: possible role in human obesity. Science 2005 Jan 28; 307(5709):584-6.
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69. Tchkonia T, Tchoukalova YD, Giorgadze N, Pirtskhalava T, Karagiannides I, Forse RA, Koo A, Stevenson M, Chinnappan D, Cartwright A, Jensen MD, Kirkland JL. Abundance of two human preadipocyte subtypes with distinct capacities for replication, adipogenesis, and apoptosis varies among fat depots. Am J Physiol Endocrinol Metab 2005 Jan; 288(1):E267-77. Epub 2004 Sep 21.
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70. Buchwald H, for the Consensus Conference Panel. Bariatric surgery for morbid obesity: Health implications for patients, health professionals, and third-party payers. Journal of the American College of Surgeons 2005; 200:593-604.
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71. Angulo P, Alba LM, Petrovic LM, Adams LA, Lindor KD, Jensen MD. Leptin, insulin resistance, and liver fibrosis in human nonalcoholic fatty liver disease. J Hepatol 2004 Dec; 41(6):943-9.
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72. Moran A, Basu R, Milla C, Jensen MD. Insulin regulation of free fatty acid kinetics in adult cystic fibrosis patients with impaired glucose tolerance. Metabolism: Clinical & Experimental 2004 Nov; 53(11):1467-72.
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73. Tchoukalova YD, Sarr MG, Jensen MD. Measuring committed preadipocytes in human adipose tissue from severely obese patients by using adipocyte fatty acid binding protein. Am J Physiol Regul Integr Comp Physiol 2004 Nov; 287(5):R1132-40.
74. Buchwald H, Avidor Y, Braunwald E, Jensen MD, Pories W, Fahrbach K, Schoelles K. Bariatric surgery: A systematic review and meta-analysis. JAMA 2004 Oct 13; 292(14):1724-37.
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75. Nielsen S, Halliwill JR, Joyner MJ, Jensen MD. Vascular response to angiotensin II in upper body obesity. Hypertension 2004 Oct; 44(4):435-41.
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76. Potretzke AM, Schmitz KH, Jensen MD. Preventing overestimation of pixels in computed tomography assessment of visceral fat. Obes Res 2004 Oct; 12(10):1698-701.
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77. Nielsen S, Guo ZK, Johnson CM, Hensrud DD, Jensen MD. Splanchnic lipolysis in human obesity. J Clin Invest 2004 Jun; 113(11):1582-8.
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78. Kanaley JA, Dall R, Moller N, Nielsen SC, Christiansen JS, Jensen MD, Jorgensen JOL. Acute exposure to GH during exercise stimulates the turnover of free fatty acids in GH-deficient men. J Appl Physiol 2004 Feb 1; 96(2):747-53.
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79. Nyholm B, Nielsen MF, Kristensen K, Nielsen S, Ostergard T, Pedersen SB, Christiansen T, Richelsen B, Jensen MD, Schmitz O. Evidence of increased visceral obesity and reduced physical fitness in healthy insulin-resistant first-degree relatives of type 2 diabetic patients. European Journal of Endocrinology 2004 Feb; 150(2):207-14.
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80. Mattison R, Jensen MD. Bariatric surgery. For the right patient, procedure can be effective. Postgrad Med 2004 Jan; 115(1):49-50, 53-8.
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81. Jensen MD, Sarr MG, Dumesic DA, Southorn PA, Levine JA. Regional uptake of meal fatty acids in humans. American Journal of Physiology - Endocrinology & Metabolism 2003 Dec 1; 285(6):E1282-8.
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82. Shadid S, Jensen MD. Effects of pioglitazone versus diet and exercise on metabolic health and fat distribution in upper body obesity. Diabetes Care 2003 Nov; 26(11):3148-52.
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83. Shadid S, Jensen MD. Effect of pioglitazone on biochemical indices of non-alcoholic fatty liver disease in upper body obesity. Clinical Gastroenterology & Hepatology 2003 Sep; 1(5):384-7.
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84. Guo ZK, Jensen MD. Accelerated intramyocellular triglyceride synthesis in skeletal muscle of high-fat-induced obese rats. Int J Obes 2003 Sep; 27(9):1014-9.
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85. Tchoukalova YD, Harteneck DA, Karwoski RA, Tarara J, Jensen MD. A quick, reliable, and automated method for fat cell sizing. J Lipid Res 2003 Sep; 44(9):1795-801.
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86. Jensen MD. Fate of fatty acids at rest and during exercise: regulatory mechanisms. Acta Physiol Scand 2003 Aug; 178(4):385-90.
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87. Basu R, Breda E, Oberg AL, Powell CC, Dalla Man C, Basu A, Vittone JL, Klee GG, Arora P, Jensen MD, Toffolo G, Cobelli C, Rizza RA. Mechanisms of the age-associated deterioration in glucose tolerance - Contribution of alterations in insulin secretion, action, and clearance. Diabetes 2003 Jul; 52(7):1738-48.
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88. Jensen MD, Cardin S, Edgerton D, Cherrington A. Splanchnic free fatty acid kinetics. Am J Physiol Endocrinol Metab 2003 Jun; 284(6):E1140-8.
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89. Nielsen S, Guo Z, Albu JB, Klein S, O'Brien PC, Jensen MD. Energy expenditure, sex, and endogenous fuel availability in humans. J Clin Invest 2003 Apr; 111(7):981-8.
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90. Schmitz KH, Jensen MD, Kugler KC, Jeffery RW, Leon AS. Strength training for obesity prevention in midlife women. Int J Obes 2003 Mar; 27(3):326-33.
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91. Shadid S, Jensen MD. Effects of growth hormone administration in human obesity. Obes Res 2003 Feb; 11(2):170-5.
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92. Jensen MD, Siverling C. Managing risk in normal volunteers participating in metabolic studies. J Investig Med 2003 Feb; 51(Suppl 1):S12-7.
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93. Shah P, Vella A, Basu A, Basu R, Adkins A, Schwenk WF, Johnson CM, Nair KS, Jensen MD, Rizza RA. Elevated free fatty acids impair glucose metabolism in women - Decreased stimulation of muscle glucose uptake and suppression of splanchnic glucose production during combined hyperinsulinemia and hyperglycemia. Diabetes 2003 Jan; 52(1):38-42.
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94. Sheehan M, Kanaley J, Jensen M. Insulin effects on free fatty acid turnover in viscerally obese and non-obese sedentary men and women. Obes Res 2003; 11(Suppl):A53.
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95. Mattison R, Jensen MD. The Adipocyte as an Endocrine Cell. Current Opinion in Endocrinology & Diabetes , 2003; 10(5):317-321.
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96. Jensen MD. Obesity: A two-part, four-article symposium. Postgrad Med 2003; 114(6):17.
97. Mattison R, Jensen M. The adipocyte as an endocrine cell. Curr Opin Endocrinol Diabet 2003; 10(5):317-21.
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98. Guo ZK, Jensen MD. Determination of skeletal muscle triglyceride synthesis using a single muscle biopsy. Metabolism 2002 Sep; 51(9):1198-205.
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99. Tchkonia T, Giorgadze N, Pirtskhalava T, Tchoukalova Y, Karagiannides I, Forse RA, DePonte M, Stevenson M, Guo W, Han J, Waloga G, Lash TL, Jensen MD, Kirkland JL. Fat depot origin affects adipogenesis in primary cultured and cloned human preadipocytes. Am J Physiol Regul Integr Comp Physiol 2002 May; 282(5):R1286-96.
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100. Shah P, Vella A, Basu A, Basu R, Adkins A, Schwenk WF, Johnson CM, Nair KS, Jensen MD, Rizza RA. Effects of free fatty acids and glycerol on splanchnic glucose metabolism and insulin extraction in nondiabetic humans. Diabetes 2002 Feb; 51(2):301-10.
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101. Jensen MD. Adipose tissue and fatty acid metabolism in humans. J R Soc Med 2002; 95(Suppl 42):3-7.
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102. Jensen MD, Chandramouli V, Schumann WC, Ekberg K, Previs SF, Gupta S, Landau BR. Sources of blood glycerol during fasting. American Journal of Physiology - Endocrinology & Metabolism 2001 Nov; 281(5):E998-E1004.
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103. Jensen MD, Ekberg K, Landau BR. Lipid metabolism during fasting. American Journal of Physiology - Endocrinology & Metabolism 2001 Oct; 281(4):E789-E793.
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104. Basu A, Basu R, Shah P, Vella A, Rizza RA, Jensen MD. Systemic and regional free fatty acid metabolism in type 2 diabetes. Am J Physiol Endocrinol Metab 2001 Jun; 280(6):E1000-6.
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105. Kesaniemi YK, Danforth E Jr, Jensen MD, Kopelman PG, Lefebvre P, Reeder BA. Dose-response issues concerning physical activity and health: an evidence-based symposium. Med Sci Sports Exerc 2001 Jun; 33(6 Suppl):S351-8.
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106. Basu A, Basu R, Shah P, Vella A, Johnson CM, Jensen M, Nair KS, Schwenk WF, Rizza RA. Type 2 diabetes impairs splanchnic uptake of glucose but does not alter intestinal glucose absorption during enteral glucose feeding: additional evidence for a defect in hepatic glucokinase activity. Diabetes 2001 Jun; 50(6):1351-62.
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107. Nielsen S, Levine J, Clay R, Jensen MD. Adipose tissue metabolism in benign symmetric lipomatosis. J Clin Endocrinol Metab 2001 Jun; 86(6):2717-20.
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108. Gravholt CH, Moller N, Jensen MD, Christiansen JS, Schmitz O. Physiological levels of glucagon do not influence lipolysis in abdominal adipose tissue as assessed by microdialysis. J Clin Endocrinol Metab 2001 May; 86(5):2085-9.
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109. Levine JA, Schleusner SJ, Jensen MD. Energy expenditure of nonexercise activity. Am J Clin Nutr 2000 Dec; 72(6):1451-4.
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110. Guo Z, Burguera B, Jensen MD. Kinetics of intramuscular triglyceride fatty acids in exercising humans. J Appl Physiol 2000 Nov; 89(5):2057-64.
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111. Nielsen S, Hensrud DD, Romanski S, Levine JA, Burguera B, Jensen MD. Body composition and resting energy expenditure in humans: role of fat, fat-free mass and extracellular fluid. International Journal of Obesity & Related Metabolic Disorders 2000 Sep; 24(9):1153-7.
112. Pritzlaff CJ, Wideman L, Blumer J, Jensen M, Abbott RD, Gaesser GA, Veldhuis JD, Weltman A. Catecholamine release, growth hormone secretion, and energy expenditure during exercise vs. recovery in men. J Appl Physiol 2000 Sep; 89(3):937-46.
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113. Romanski SA, Nelson RM, Jensen MD. Meal fatty acid uptake in human adipose tissue: technical and experimental design issues. American Journal of Physiology - Endocrinology & Metabolism 2000 Aug; 279(2):E447-54.
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114. Romanski SA, Nelson RM, Jensen MD. Meal fatty acid uptake in adipose tissue: gender effects in nonobese humans. American Journal of Physiology - Endocrinology & Metabolism 2000 Aug; 279(2):E455-62.
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115. Balsiger BM, Kennedy FP, Abu-Lebdeh HS, Collazo-Clavell M, Jensen MD, O'Brien T, Hensrud DD, Dinneen SF, Thompson GB, Que FG, Williams DE, Clark MM, Grant JE, Frick MS, Mueller RA, Mai JL, Sarr MG. Prospective evaluation of Roux-en-Y gastric bypass as primary operation for medically complicated obesity. Mayo Clin Proc 2000 Jul; 75(7):673-80.
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116. Burguera B, Couce ME, Curran GL, Jensen MD, Lloyd RV, Cleary MP, Poduslo JF. Obesity is associated with a decreased leptin transport across the blood-brain barrier in rats. Diabetes 2000 Jul; 49(7):1219-23.
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117. Sheehan MT, Jensen MD. Metabolic complications of obesity. Pathophysiologic considerations. Med Clin North Am 2000 Mar; 84(2):363-85, vi.
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118. Burguera B, Couce ME, Long J, Lamsam J, Laakso K, Jensen MD, Parisi JE, Lloyd RV. The long form of the leptin receptor (OB-Rb) is widely expressed in the human brain. Neuroendocrinology 2000 Mar; 71(3):187-95.
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119. Jensen MD. Genetic and environmental contributions. Nutr Rev 2000 Mar; 58(3 Pt 2):S22-4.
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120. Levine JA, Abboud L, Barry M, Reed JE, Sheedy PF, Jensen MD. Measuring leg muscle and fat mass in humans: comparison of CT and dual-energy X-ray absorptiometry. J Appl Physiol 2000 Feb; 88(2):452-6.
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121. Basu A, Basu R, Shah P, Vella A, Johnson CM, Nair KS, Jensen MD, Schwenk WF, Rizza RA. Effects of type 2 diabetes on the ability of insulin and glucose to regulate splanchnic and muscle glucose metabolism - evidence for a defect in haptic glucokinase activity. Diabetes 2000 Feb; 49(2):272-83.
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122. Jensen MD. Androgen effect on body composition and fat metabolism... . Mayo Clin Proc 2000 Jan; 75(Suppl):S65-9.
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123. Burguera B, Proctor D, Dietz N, Guo Z, Joyner M, Jensen MD. Leg free fatty acid kinetics during exercise in men and women. Am J Physiol Endocrinol Metab 2000 Jan; 278(1):E113-7.
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124. Hensrud DD, Connolly HM, Grogan M, Miller FA, Bailey KR, Jensen MD. Echocardiographic improvement over time after cessation of use of fenfluramine and phentermine. Mayo Clin Proc 1999 Dec; 74(12):1191-7.
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125. Nielsen S, Jensen MD. Relationship between urinary albumin excretion, body composition, and hyperinsulinemia in normotensive glucose-tolerant adults. Diabetes Care 1999 Oct; 22(10):1728-33.
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126. Guo Z, Jensen MD. Blood glycerol is an important precursor for intramuscular triacylglycerol synthesis. J Biol Chem 1999 Aug 20; 274(34):23702-6.
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127. Guo Z, Hensrud DD, Johnson CM, Jensen MD. Regional postprandial fatty acid metabolism in different obesity phenotypes. Diabetes 1999 Aug; 48(8):1586-92.
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128. Levine JA, Eberhardt NL, Jensen MD. Leptin responses to overfeeding: relationship with body fat and nonexercise activity thermogenesis. J Clin Endocrinol Metab 1999 Aug; 84(8):2751-4.
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129. Jensen MD, Hensrud D, O'Brien PC, Nielsen S. Collection and interpretation of plasma leptin concentration data in humans. Obes Res 1999 May; 7(3):241-5.
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130. Jensen MD. Regional glycerol and free fatty acid metabolism before and after meal ingestion. Am J Physiol 1999 May; 276(5 Pt 1):E863-9.
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131. Thomas T, Gori F, Khosla S, Jensen MD, Burguera B, Riggs BL. Leptin acts on human marrow stromal cells to enhance differentiation to osteoblasts and to inhibit differentiation to adipocytes. Endocrinology 1999 Apr; 140(4):1630-8.
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132. Levine JA, Eberhardt NL, Jensen MD. Role of nonexercise activity thermogenesis in resistance to fat gain in humans. Science 1999 Jan 8; 283(5399):212-4.
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133. Meek SE, Nair KS, Jensen MD. Insulin regulation of regional free fatty acid metabolism. Diabetes 1999 Jan; 48(1):10-4.
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134. Jensen MD, Moller N, Nair KS, Eisenberg P, Landt M, Klein S. Regional leptin kinetics in humans. Am J Clin Nutr 1999 Jan; 69(1):18-21.
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135. Folsom AR, Jensen MD, Jacobs DR Jr, Hilner JE, Tsai AW, Schreiner PJ. Serum leptin and weight gain over 8 years in African American and Caucasian young adults. Obes Res 1999 Jan; 7(1):1-8.
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136. Jensen MD. Medical management of obesity. Semin Gastrointest Dis 1998 Oct; 9(4):156-62.
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137. Levine JA, Eberhardt NL, Jensen MD, O'Brien T. Adenoviral-mediated gene transfer to human adipocytes in vitro, and human adipose tissue ex vivo and rabbit femoral adipose tissue in vivo. J Nutr Sci Vitaminol 1998 Aug; 44(4):569-72.
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138. Dumesic DA, Abbott DH, Eisner JR, Herrmann RR, Reed JE, Welch TJ, Jensen MD. Pituitary desensitization to gonadotropin-releasing hormone increases abdominal adiposity in hyperandrogenic anovulatory women. Fertility & Sterility 1998 Jul; 70(1):94-101.
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139. Judd RL, Nelson R, Klein S, Jensen MD, Miles JM. Measurement of plasma glycerol specific activity by high performance liquid chromatography to determine glycerol flux. J Lipid Res 1998 May; 39(5):1106-10.
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140. Guo Z, Jensen MD. Intramuscular fatty acid metabolism evaluated with stable isotopic tracers. J Appl Physiol 1998 May; 84(5):1674-9.
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141. Levine JA, Jensen MD, Eberhardt NL, O'Brien T. Adipocyte macrophage colony-stimulating factor is a mediator of adipose tissue growth. J Clin Invest 1998 Apr 15; 101(8):1557-64.
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142. Jensen MD. Diet effects on fatty acid metabolism in lean and obese humans. Am J Clin Nutr 1998 Mar; 67(3 Suppl S):S 531-S 534.
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143. Jensen MD, Levine J. Effects of oral contraceptives on free fatty acid metabolism in women. Metabolism: Clinical & Experimental 1998 Mar; 47(3):280-4.
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144. Burguera B, Jensen MD. Obesity - is the brain responsible? Curr Opin Gastroenterol 1998 Mar; 14(2):147-150.
145. Jensen MD, Nguyen TT, Hernandez Mijares A, Johnson CM, Murray MJ. Effects of gender on resting leg blood flow: implications for measurement of regional substrate oxidation. J Appl Physiol 1998 Jan; 84(1):141-5.
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146. Couce ME, Burguera B, Parisi JE, Jensen MD, Lloyd RV. Localization of leptin receptor in the human brain. Neuroendocrinology 1997 Sep; 66(3):145-50.
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147. Guo Z, Nielsen S, Burguera B, Jensen MD. Free fatty acid turnover measured using ultralow doses of [U-13C]palmitate. J Lipid Res 1997 Sep; 38(9):1888-95.
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148. Nielsen S, Jensen MD. Obesity and cardiovascular disease: is body structure a factor? Curr Opin Lipidol 1997 Aug; 8(4):200-4.
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149. Guo ZK, Johnson CM, Jensen MD. Regional lipolytic responses to isoproterenol in women. Am J Physiol Endocrinol Metab 1997 Jul; 273(1):E 108-12.
150. Divertie GD, Jensen MD, Cryer PE, Miles JM. Lipolytic responsiveness to epinephrine in nondiabetic and diabetic humans. Am J Physiol 1997 Jun; 272(6 Pt 1):E1130-5.
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151. Jensen MD. Lipolysis: contribution from regional fat. Annu Rev Nutr 1997; 17:127-39.
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152. Jensen MD. Health consequences of fat distribution. Horm Res 1997; 48(Suppl 5):88-92.
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153. Nguyen TT, Mijares AH, Johnson CM, Jensen MD. Postprandial leg and splanchnic fatty acid metabolism in non-obese men and women. Am J Physiol Endocrinol Metab 1996 Dec; 271(6):E 965-E 972.
154. Nguyen TT, Hernandez Mijares A, Johnson CM, Jensen MD. Postprandial leg and splanchnic fatty acid metabolism in nonobese men and women. Am J Physiol 1996 Dec; 271(6 Pt 1):E965-72.
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155. Jensen MD, Johnson CM. Contribution of leg and splanchnic free fatty acid (FFA) kinetics to postabsorptive FFA flux in men and women. Metabolism: Clinical & Experimental 1996 May; 45(5):662-6.
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156. Jensen MD, Cryer PE, Johnson CM, Murray MJ. Effects of epinephrine on regional free fatty acid and energy metabolism in men and women. Am J Physiol Endocrinol Metab 1996 Feb; 270(2):E 259-E 264.
157. Guo ZK, Johnson CM, Jensen MD. Effect of isoproterenol on systemic and regional lipolysis in women. Journal of Investigative Medicin 1996; 44(7):355A.
158. Jensen MD. Gender differences in regional fatty acid metabolism before and after meal ingestion. J Clin Invest 1995 Nov; 96(5):2297-303.
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159. Hernandez Mijares A, Jensen MD. Contribution of blood flow to leg glucose uptake during a mixed meal. Diabetes 1995 Oct; 44(10):1165-9.
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160. Kanaley JA, Mottram CD, Scanlon PD, Jensen MD. Fatty acid kinetic responses to running above or below lactate threshold. J Appl Physiol 1995 Aug; 79(2):439-47.
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161. Jensen MD, Johnson CM, Cryer PE, Murray MJ. Thermogenesis after a mixed meal: role of leg and splanchnic tissues in men and women. Am J Physiol 1995 Mar; 268(3 Pt 1):E433-8.
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162. Jensen MD, Kanaley JA, Reed JE, Sheedy PF. Measurement of abdominal and visceral fat with computed tomography and dual-energy x-ray absorptiometry. Am J Clin Nutr 1995 Feb; 61(2):274-8.
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163. Sarr MG, Felty CL, Hilmer DM, Urban DL, O'Connor G, Hall BA, Rooke TW, Jensen MD. Technical and practical considerations involved in operations on patients weighing more than 270 kg. Arch Surg 1995 Jan; 130(1):102-5.
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164. Roust LR, Kottke BA, Jensen MD. Serum lipid responses to a eucaloric high-complex carbohydrate diet in different obesity phenotypes. Mayo Clin Proc 1994 Oct; 69(10):930-6.
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165. Roust LR, Hammel KD, Jensen MD. Effects of isoenergetic, low-fat diets on energy metabolism in lean and obese women. Am J Clin Nutr 1994 Oct; 60(4):470-5.
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166. Jensen MD, Martin ML, Cryer PE, Roust LR. Effects of estrogen on free fatty acid metabolism in humans. Am J Physiol 1994 Jun; 266(6 Pt 1):E914-20.
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167. Katz H, Homan M, Jensen M, Caumo A, Cobelli C, Rizza R. Assessment of insulin action in NIDDM in the presence of dynamic changes in insulin and glucose concentration. Diabetes 1994 Feb; 43(2):289-96.
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168. Coppack SW, Jensen MD, Miles JM. In vivo regulation of lipolysis in humans. J Lipid Res 1994 Feb; 35(2):177-93.
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169. Cersosimo E, Coppack S, Jensen M. Lack of effect of hyperglycemia on lipolysis in humans. Am J Physiol 1993 Dec; 265(6 Pt 1):E821-4.
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170. Roust LR, Jensen MD. Postprandial free fatty acid kinetics are abnormal in upper body obesity. Diabetes 1993 Nov; 42(11):1567-73.
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171. Jensen MD, Kanaley JA, Roust LR, O'Brien PC, Braun JS, Dunn WL, Wahner HW. Assessment of body composition with use of dual-energy absorptiometry: evaluation and comparison with other methods. Mayo Clin Proc 1993 Sep; 68:867-873.
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172. Kanaley JA, Cryer PE, Jensen MD. Fatty acid kinetic responses to exercise. Effects of obesity, body fat distribution, and energy-restricted diet. J Clin Invest 1993 Jul; 92(1):255-61.
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173. Kanaley JA, Haymond MW, Jensen MD. Effects of exercise and weight loss on leucine turnover in different types of obesity. Am J Physiol 1993 May; 264(5 Pt 1):E687-92.
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174. Lee PD, Jensen MD, Divertie GD, Heiling VJ, Katz HH, Conover CA. Insulin-like growth factor-binding protein-1 response to insulin during suppression of endogenous insulin secretion. Metabolism: Clinical & Experimental 1993 Apr; 42(4):409-14.
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175. Loprinzi CL, Schaid DJ, Dose AM, Burnham NL, Jensen MD. Body-composition changes in patients who gain weight while receiving megestrol acetate. J Clin Oncol 1993 Jan; 11(1):152-4.
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176. Kanaley JA, Andresen-Reid ML, Oenning L, Kottke BA, Jensen MD. Differential health benefits of weight loss in upper-body and lower-body obese women. Am J Clin Nutr 1993 Jan; 57(1):20-6.
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177. Loprinzi CL, Jensen MD, Jiang NS, Schaid DJ. Effect of megestrol acetate on the human pituitary-adrenal axis. Mayo Clin Proc 1992 Dec; 67(12):1160-2.
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178. Conover CA, Lee PD, Kanaley JA, Clarkson JT, Jensen MD. Insulin regulation of insulin-like growth factor binding protein-1 in obese and nonobese humans. Journal of Clinical Endocrinology & Metabolism 1992 Jun; 74(6):1355-60.
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179. Jensen MD. Research techniques for body composition assessment. J Am Diet Assoc 1992 Apr; 92(4):454-60.
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180. Heiling VJ, Jensen MD. Free fatty acid metabolism in the follicular and luteal phases of the menstrual cycle. J Clin Endocrinol Metab 1992 Apr; 74(4):806-10.
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181. Loprinzi CL, Johnson PA, Jensen M. Megestrol acetate for anorexia and cachexia. Oncology 1992; 49(Suppl 2):46-9.
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182. Heiling VJ, Miles JM, Jensen MD. How valid are isotopic measurements of fatty acid oxidation? Am J Physiol 1991 Nov; 261(PART 1 OF 2 PARTS):E572-E577.
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183. Homan M, Nicholson CP, Katz H, Perkins J, Haymond M, Jensen M, Butler P, Rizza R. Effects of chronic systemic insulin delivery on insulin action in dogs. Diabetologia 1991 Oct; 34(10):702-8.
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184. Nightengale ML, Sarr MG, Kelly KA, Jensen MD, Zinsmeister AR, Palumbo PJ. Prospective evaluation of vertical banded gastroplasty as the primary operation for morbid obesity. Mayo Clin Proc 1991 Aug; 66(8):773-82.
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185. Martin ML, Jensen MD. Effects of body fat distribution on regional lipolysis in obesity. J Clin Invest 1991 Aug; 88(2):609-13.
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186. Jensen MD. Adrenergic regulation of lipolysis in a patient with lipoatrophy of the upper body. Mayo Clin Proc 1991 Jul; 66(7):704-10.
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187. Bailey JW, Jensen MD, Miles JM. Effects of intravenous methyl palmoxirate on the turnover and oxidation of fatty acids in conscious dogs. Metabolism: Clinical & Experimental 1991 Apr; 40(4):428-31.
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188. Jensen MD, Heiling VJ. Heated hand vein blood is satisfactory for measurements during free fatty acid kinetic studies. Metabolism: Clinical & Experimental 1991 Apr; 40(4):406-9.
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189. Jensen MD, Heiling VJ, Miles JM. Effects of glucagon on free fatty acid metabolism in humans. J Clin Endocrinol Metab 1991 Feb; 72(2):308-15.
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190. Jensen MD, Haymond MW. Protein metabolism in obesity: effects of body fat distribution and hyperinsulinemia on leucine turnover. Am J Clin Nutr 1991 Jan; 53(1):172-6.
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191. Jensen MD. Regulation of forearm lipolysis in different types of obesity. In vivo evidence for adipocyte heterogeneity. J Clin Invest 1991 Jan; 87(1):187-93.
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192. Divertie GD, Jensen MD, Miles J. Stimulation of lipolysis in humans by physiological hypercortisolemia. Diabetes 1991; 40:1228-1232.
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193. Caruso M, Divertie GD, Jensen MD, Miles JM. Lack of effect of hyperglycemia on lipolysis in humans. Am J Physiol 1990 Oct; 259(4 Pt 1):E542-7.
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194. Jensen MD, Heiling V, Miles JM. Measurement of non-steady-state free fatty acid turnover. Am J Physiol 1990 Jan; 258(1 Pt 1):E103-8.
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195. Jensen MD, Caruso M, Heiling V, Miles JM. Insulin regulation of lipolysis in nondiabetic and IDDM subjects. Diabetes 1989 Dec; 38(12):1595-601.
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196. Jensen MD, Haymond MW, Rizza RA, Cryer PE, Miles JM. Influence of body fat distribution on free fatty acid metabolism in obesity. J Clin Invest 1989 Apr; 83(4):1168-73.
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197. Jensen MD, Braun JS, Vetter RJ, Marsh HM. Measurement of body potassium with a whole-body counter: relationship between lean body mass and resting energy expenditure. Mayo Clin Proc 1988 Sep; 63(9):864-8.
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198. Jensen MD, Miles JM, Gerich JE, Cryer PE, Haymond MW. Preservation of insulin effects on glucose production and proteolysis during fasting. Am J Physiol 1988 Jun; 254(PART 1):E707-E707.
199. Jensen MD, Rogers PJ, Ellman MG, Miles JM. Choice of infusion-sampling mode for tracer studies of free fatty acid metabolism. Am J Physiol 1988 May; 254(5 Pt 1):E562-5.
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200. Lindor KD, Hughes RW Jr, Ilstrup DM, Jensen MD. Intragastric balloons in comparison with standard therapy for obesity--a randomized, double-blind trial. Mayo Clin Proc 1987 Nov; 62(11):992-6.
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201. Miles JM, Ellman MG, McClean KL, Jensen MD. Validation of a new method for determination of free fatty acid turnover. Am J Physiol 1987 Mar; 252(3 Pt 1):E431-8.
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202. Jensen MD, Haymond MW, Gerich JE, Cryer PE, Miles JM. Lipolysis during fasting. Decreased suppression by insulin and increased stimulation by epinephrine. J Clin Invest 1987 Jan; 79(1):207-13.
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203. Jensen MD, Miles JM. The roles of diet and exercise in the management of patients with insulin-dependent diabetes mellitus. Mayo Clin Proc 1986 Oct; 61(10):813-9.
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204. Miles JM, Jensen MD. Complications of insulin-dependent diabetes mellitus: management of insulin reactions and acute illness. Mayo Clin Proc 1986 Oct; 61(10):820-4.
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205. Jensen MD, Van Heerden JA, McConahey WM, Charboneau JW. Cystic lymphangioma presenting as subacute thyroiditis. Minn Med 1986 Aug; 69(8):463-4.
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206. Jensen MD, Handwerger BS, Scheithauer BW, Carpenter PC, Mirakian R, Banks PM. Lymphocytic hypophysitis with isolated corticotropin deficiency. Ann Intern Med 1986 Aug; 105(2):200-3.
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207. Jensen MD, Gharib H, Naessens JM, van Heerden JA, Mayberry WE. Treatment of toxic multinodular goiter (Plummer's disease): surgery or radioiodine? World J Surg 1986 Aug; 10(4):673-80.
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208. Jensen MD, McAllister CK. Antibiotic-associated pseudomembranous colitis. Mo Med 1979 Oct; 76(10):534-6.
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209. Basu R, Dalla Man C, Campioni M, Basu A, Nair KS, Jensen MD, Khosla S, Klee G, Toffolo G, Cobelli C, Rizza RA. Two years of treatment with dehydroepiandrosterone does not improve insulin secretion, insulin action, or postprandial glucose turnover in elderly men or women. Diabetes 2007 Mar; 56(3):753-66.
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210. Basu R, Man CD, Campioni M, Basu A, Nair KS, Jensen MD, Khosla S, Klee G, Toffolo G, Cobelli C, Rizza RA. Two years of treatment with dehydroepiandrosterone does not improve insulin secretion, insulin action, or postprandial glucose turnover in elderly men or women. Diabetes 2007 Mar; 56(3):753-66.
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