Publications - Joseph H. Szurszewski, Ph.D.

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  1. Creedon CT, Verhulst PJ, Choi KM, Mason JE, Linden DR, Szurszewski JH, Gibbons SJ, Farrugia G. Assessment of gastric emptying in non-obese diabetic mice using a [13C]-octanoic acid breath test. J Vis Exp. 2013; (73):e50301. Epub 2013 Mar 23.
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  2. Linden DR, Furne J, Stoltz GJ, Abdel-Rehim MS, Levitt MD, Szurszewski JH. Sulphide quinone reductase contributes to hydrogen sulphide metabolism in murine peripheral tissues but not in the CNS. Br J Pharmacol. 2012 Apr; 165(7):2178-90.
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  3. Strege PR, Bernard CE, Kraichely RE, Mazzone A, Sha L, Beyder A, Gibbons SJ, Linden DR, Kendrick ML, Sarr MG, Szurszewski JH, Farrugia G. Hydrogen sulfide is a partially redox-independent activator of the human jejunum Na+ channel, Nav1.5. Am J Physiol Gastrointest Liver Physiol. 2011 Jun; 300(6):G1105-14. Epub 2011 Mar 10.
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  4. Mazzone A, Bernard CE, Strege PR, Beyder A, Galietta LJ, Pasricha PJ, Rae JL, Parkman HP, Linden DR, Szurszewski JH, Ordog T, Gibbons SJ, Farrugia G. Altered expression of Ano1 variants in human diabetic gastroparesis. J Biol Chem. 2011 Apr 15; 286(15):13393-403. Epub 2011 Feb 24.
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  5. Sha L, Farrugia G, Linden DR, Szurszewski JH. The transwall gradient across the mouse colonic circular muscle layer is carbon monoxide dependent. FASEB J. 2010 Oct; 24(10):3840-9. Epub 2010 Jun 11.
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  6. Matsuda NM, Miller SM, Szurszewski JH. Heme-oxygenase-2 immunolabelling in pig jejunum. Acta Histochem. 2010 Jul; 112(4):402-6. Epub 2009 Feb 20.
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  7. Choi KM, Kashyap PC, Dutta N, Stoltz GJ, Ordog T, Shea Donohue T, Bauer AJ, Linden DR, Szurszewski JH, Gibbons SJ, Farrugia G. CD206-positive M2 macrophages that express heme oxygenase-1 protect against diabetic gastroparesis in mice. Gastroenterology. 2010 Jun; 138(7):2399-409, 2409.e1. Epub 2010 Feb 20.
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  8. Kashyap PC, Choi KM, Dutta N, Linden DR, Szurszewski JH, Gibbons SJ, Farrugia G. Carbon monoxide reverses diabetic gastroparesis in NOD mice. Am J Physiol Gastrointest Liver Physiol. 2010 Jun; 298(6):G1013-9. Epub 2010 Apr 08.
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  9. Linden DR, Levitt MD, Farrugia G, Szurszewski JH. Endogenous production of H2S in the gastrointestinal tract: still in search of a physiologic function. Antioxid Redox Signal. 2010 May 1; 12(9):1135-46.
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  10. Strege PR, Sha L, Beyder A, Bernard CE, Perez-Reyes E, Evangelista S, Gibbons SJ, Szurszewski JH, Farrugia G. T-type Ca(2+) channel modulation by otilonium bromide. Am J Physiol Gastrointest Liver Physiol. 2010 May; 298(5):G706-13. Epub 2010 Mar 04.
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  11. Gibbons SJ, De Giorgio R, Faussone Pellegrini MS, Garrity-Park MM, Miller SM, Schmalz PF, Young-Fadok TM, Larson DW, Dozois EJ, Camilleri M, Stanghellini V, Szurszewski JH, Farrugia G. Apoptotic cell death of human interstitial cells of Cajal. Neurogastroenterol Motil. 2009 Jan; 21(1):85-93. Epub 2008 Sep 16.
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  12. Choi KM, Gibbons SJ, Nguyen TV, Stoltz GJ, Lurken MS, Ordog T, Szurszewski JH, Farrugia G. Heme oxygenase-1 protects interstitial cells of Cajal from oxidative stress and reverses diabetic gastroparesis. Gastroenterology. 2008 Dec; 135(6):2055-64, 2064.e1-2. Epub 2008 Sep 11.
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  13. Linden DR, Sha L, Mazzone A, Stoltz GJ, Bernard CE, Furne JK, Levitt MD, Farrugia G, Szurszewski JH. Production of the gaseous signal molecule hydrogen sulfide in mouse tissues. J Neurochem. 2008 Aug; 106(4):1577-85. Epub 2008 May 29.
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  14. Miller SM, Narasimhan RA, Schmalz PF, Soffer EE, Walsh RM, Krishnamurthi V, Pasricha PJ, Szurszewski JH, Farrugia G. Distribution of interstitial cells of Cajal and nitrergic neurons in normal and diabetic human appendix. Neurogastroenterol Motil. 2008 Apr; 20(4):349-57. Epub 2007 Dec 07.
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  15. Choi KM, Zhu J, Stoltz GJ, Vernino S, Camilleri M, Szurszewski JH, Gibbons SJ, Farrugia G. Determination of gastric emptying in nonobese diabetic mice. Am J Physiol Gastrointest Liver Physiol. 2007 Nov; 293(5):G1039-45. Epub 2007 Sep 20.
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  16. Wouters MM, Gibbons SJ, Roeder JL, Distad M, Ou Y, Strege PR, Szurszewski JH, Farrugia G. Exogenous serotonin regulates proliferation of interstitial cells of Cajal in mouse jejunum through 5-HT2B receptors. Gastroenterology. 2007 Sep; 133(3):897-906. Epub 2007 Jun 20.
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  17. Sha L, Farrugia G, Harmsen WS, Szurszewski JH. Membrane potential gradient is carbon monoxide-dependent in mouse and human small intestine. Am J Physiol Gastrointest Liver Physiol. 2007 Aug; 293(2):G438-45. Epub 2007 May 17.
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  18. Choi KM, Gibbons SJ, Roeder JL, Lurken MS, Zhu J, Wouters MM, Miller SM, Szurszewski JH, Farrugia G. Regulation of interstitial cells of Cajal in the mouse gastric body by neuronal nitric oxide. Neurogastroenterol Motil. 2007 Jul; 19(7):585-95.
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  19. Xue L, Camilleri M, Locke GR 3rd, Schuurkes JA, Meulemans A, Coulie BJ, Szurszewski JH, Farrugia G. Serotonergic modulation of murine fundic tone. Am J Physiol Gastrointest Liver Physiol. 2006 Dec; 291(6):G1180-6. Epub 2006 Jul 27.
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  20. Xue L, Locke GR, Camilleri M, Schuurkes JA, Meulemans A, Coulie BJ, Szurszewski JH, Farrugia G. Effect of modulation of serotonergic, cholinergic, and nitrergic pathways on murine fundic size and compliance measured by ultrasonomicrometry. Am J Physiol Gastrointest Liver Physiol. 2006 Jan; 290(1):G74-82. Epub 2005 Sep 15.
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  21. Lim I, Gibbons SJ, Lyford GL, Miller SM, Strege PR, Sarr MG, Chatterjee S, Szurszewski JH, Shah VH, Farrugia G. Carbon monoxide activates human intestinal smooth muscle L-type Ca2+ channels through a nitric oxide-dependent mechanism. Am J Physiol Gastrointest Liver Physiol. 2005 Jan; 288(1):G7-14.
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  22. Ermilov LG, Schmalz PF, Miller SM, Szurszewski JH. PACAP modulation of the colon-inferior mesenteric ganglion reflex in the guinea pig. J Physiol. 2004 Oct 1; 560(Pt 1):231-47. Epub 2004 Jul 29.
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  23. Matsuda NM, Miller SM, Sha L, Farrugia G, Szurszewski JH. Mediators of non-adrenergic non-cholinergic inhibitory neurotransmission in porcine jejunum. Neurogastroenterol Motil. 2004 Oct; 16(5):605-12.
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  24. Vernino S, Ermilov LG, Sha L, Szurszewski JH, Low PA, Lennon VA. Passive transfer of autoimmune autonomic neuropathy to mice. J Neurosci. 2004 Aug 11; 24(32):7037-42.
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  25. Sha L, Miller SM, Szurszewski JH. Morphology and electrophysiology of neurons in dog paraventricular nucleus: in vitro study. Brain Res. 2004 Jun 4; 1010(1-2):95-107.
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  26. Szurszewski JH, Farrugia G. Carbon monoxide is an endogenous hyperpolarizing factor in the gastrointestinal tract. Neurogastroenterol Motil. 2004 Apr; 16(Suppl 1):81-5.
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  27. Strege PR, Ou Y, Sha L, Rich A, Gibbons SJ, Szurszewski JH, Sarr MG, Farrugia G. Sodium current in human intestinal interstitial cells of Cajal. Am J Physiol Gastrointest Liver Physiol. 2003 Dec; 285(6):G1111-21. Epub 2003 Jul 31.
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  28. Miller SM, Szurszewski JH. Circumferential, not longitudinal, colonic stretch increases synaptic input to mouse prevertebral ganglion neurons. Am J Physiol Gastrointest Liver Physiol. 2003 Dec; 285(6):G1129-38. Epub 2003 Aug 14.
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  29. Kobilo T, Szurszewski JH, Farrugia G, Hanani M. Coupling and innervation patterns of interstitial cells of Cajal in the deep muscular plexus of the guinea-pig. Neurogastroenterol Motil. 2003 Dec; 15(6):635-41.
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  30. Gibbons SJ, Rich A, Distad MA, Miller SM, Schmalz PF, Szurszewski JH, Sha L, Blume-Jensen P, Farrugia G. Kit/stem cell factor receptor-induced phosphatidylinositol 3'-kinase signalling is not required for normal development and function of interstitial cells of Cajal in mouse gastrointestinal tract. Neurogastroenterol Motil. 2003 Dec; 15(6):643-53.
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  31. Farrugia G, Lei S, Lin X, Miller SM, Nath KA, Ferris CD, Levitt M, Szurszewski JH. A major role for carbon monoxide as an endogenous hyperpolarizing factor in the gastrointestinal tract. Proc Natl Acad Sci U S A. 2003 Jul 8; 100(14):8567-70. Epub 2003 Jun 27.
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  32. Ermilov LG, Miller SM, Schmalz PF, Hanani M, Lennon VA, Szurszewski JH. Morphological characteristics and immunohistochemical detection of nicotinic acetylcholine receptors on intestinofugal afferent neurones in guinea-pig colon. Neurogastroenterol Motil. 2003 Jun; 15(3):289-98.
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  33. Feldstein AE, Miller SM, El-Youssef M, Rodeberg D, Lindor NM, Burgart LJ, Szurszewski JH, Farrugia G. Chronic intestinal pseudoobstruction associated with altered interstitial cells of Cajal networks. J Pediatr Gastroenterol Nutr. 2003 Apr; 36(4):492-7.
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  34. Lennon VA, Ermilov LG, Szurszewski JH, Vernino S. Immunization with neuronal nicotinic acetylcholine receptor induces neurological autoimmune disease. J Clin Invest. 2003 Mar; 111(6):907-13.
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  35. Rich A, Miller SM, Gibbons SJ, Malysz J, Szurszewski JH, Farrugia G. Local presentation of Steel factor increases expression of c-kit immunoreactive interstitial cells of Cajal in culture. Am J Physiol Gastrointest Liver Physiol. 2003 Feb; 284(2):G313-20. Epub 2002 Oct 09.
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  36. Malysz J, Farrugia G, Ou YJ, Szurszewski JH, Nehra A, Gibbons SJ. The Kv2.2 alpha subunit contributes to delayed rectifier K+ currents in myocytes from rabbit corpus cavernosum. J Androl. 2002 Nov-Dec; 23(6):899-910.
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  37. Ou Y, Gibbons SJ, Miller SM, Strege PR, Rich A, Distad MA, Ackerman MJ, Rae JL, Szurszewski JH, Farrugia G. SCN5A is expressed in human jejunal circular smooth muscle cells. Neurogastroenterol Motil. 2002 Oct; 14(5):477-86.
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  38. Lyford GL, He CL, Soffer E, Hull TL, Strong SA, Senagore AJ, Burgart LJ, Young-Fadok T, Szurszewski JH, Farrugia G. Pan-colonic decrease in interstitial cells of Cajal in patients with slow transit constipation. Gut. 2002 Oct; 51(4):496-501.
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  39. Lyford GL, Strege PR, Shepard A, Ou YJ, Ermilov L, Miller SM, Gibbons SJ, Rae JL, Szurszewski JH, Farrugia G. alpha(1C) (Ca(v)1.2) L-type calcium channel mediates mechanosensitive calcium regulation. Am J Physiol Cell Physiol. 2002 Sep; 283(3):C1001-8.
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  40. Miller SM, Szurszewski JH. Relationship between colonic motility and cholinergic mechanosensory afferent synaptic input to mouse superior mesenteric ganglion. Neurogastroenterol Motil. 2002 Aug; 14(4):339-48.
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  41. Szurszewski JH, Ermilov LG, Miller SM. Prevertebral ganglia and intestinofugal afferent neurones. Gut. 2002 Jul; 51 Suppl 1:i6-10.
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  42. Pardi DS, Miller SM, Miller DL, Burgart LJ, Szurszewski JH, Lennon VA, Farrugia G. Paraneoplastic dysmotility: loss of interstitial cells of Cajal. Am J Gastroenterol. 2002 Jul; 97(7):1828-33.
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  43. Rich A, Hanani M, Ermilov LG, Malysz J, Belzer V, Szurszewski JH, Farrugia G. Physiological study of interstitial cells of Cajal identified by vital staining. Neurogastroenterol Motil. 2002 Apr; 14(2):189-96.
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  44. Holm AN, Rich A, Miller SM, Strege P, Ou Y, Gibbons S, Sarr MG, Szurszewski JH, Rae JL, Farrugia G. Sodium current in human jejunal circular smooth muscle cells. Gastroenterology. 2002 Jan; 122(1):178-87.
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  45. Kubota M, Suita S, Kamimura T, Ito Y, Szurszewski JH. Electrophysiological properties of the aganglionic segment in Hirschsprung's disease. Surgery. 2002 Jan; 131(1 Suppl S):S288-93.
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  46. Malysz J, Gibbons SJ, Miller SM, Gettman M, Nehra A, Szurszewski JH, Farrugia G. Potassium outward currents in freshly dissociated rabbit corpus cavernosum myocytes. J Urol. 2001 Sep; 166(3):1167-77.
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  47. He CL, Soffer EE, Ferris CD, Walsh RM, Szurszewski JH, Farrugia G. Loss of interstitial cells of cajal and inhibitory innervation in insulin-dependent diabetes. Gastroenterology. 2001 Aug; 121(2):427-34.
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  48. Simopoulos DN, Gibbons SJ, Malysz J, Szurszewski JH, Farrugia G, Ritman EL, Moreland RB, Nehra A. Corporeal structural and vascular micro architecture with X-ray micro computerized tomography in normal and diabetic rabbits: histopathological correlation. J Urol. 2001 May; 165(5):1776-82.
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  49. Miller SM, Reed D, Sarr MG, Farrugia G, Szurszewski JH. Haem oxygenase in enteric nervous system of human stomach and jejunum and co-localization with nitric oxide synthase. Neurogastroenterol Motil. 2001 Apr; 13(2):121-31.
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  50. Sha L, Miller SM, Szurszewski JH. Electrophysiological effects of GABA on cat pancreatic neurons. Am J Physiol Gastrointest Liver Physiol. 2001 Mar; 280(3):G324-31.
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  51. Sha L, Westerlund J, Szurszewski JH, Bergsten P. Amplitude modulation of pulsatile insulin secretion by intrapancreatic ganglion neurons. Diabetes. 2001 Jan; 50(1):51-5.
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  52. Kubota M, Suita S, Ito Y, Szurszewski JH. Membrane properties and innervation of the aganglionic segment of smooth muscle in Hirschsprung's disease. Fukuoka Igaku Zasshi - Fukuoka Acta Medica. 2001; 92(10):341-6.
  53. Ermilov LG, Miller SM, Schmalz PF, Hanani M, Szurszewski JH. The three-dimensional structure of neurons in the guinea pig inferior mesenteric and pelvic hypogastric ganglia. Auton Neurosci. 2000 Oct 2; 83(3):116-26.
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  54. Xue L, Farrugia G, Szurszewski JH. Effect of exogenous ATP on canine jejunal smooth muscle. Am J Physiol Gastrointest Liver Physiol. 2000 May; 278(5):G725-33.
  55. Xue L, Farrugia G, Miller SM, Ferris CD, Snyder SH, Szurszewski JH. Carbon monoxide and nitric oxide as coneurotransmitters in the enteric nervous system: evidence from genomic deletion of biosynthetic enzymes. Proc Natl Acad Sci U S A. 2000 Feb 15; 97(4):1851-5.
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  56. He CL, Burgart L, Wang L, Pemberton J, Young-Fadok T, Szurszewski J, Farrugia G. Decreased interstitial cell of Cajal volume in patients with slow-transit constipation. Gastroenterology. 2000 Jan; 118(1):14-21.
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  57. Miller SM, Sha L, Schmalz PF, Farrugia G, Benarroch EE, Berthoud H, Szurszewski JH. Distribution of leptin receptors in peripheral autonomic ganglia. Autonomic Neuroscience: Basic and Clinical. 2000; 82:10-11.
  58. Farrugia G, Szurszewski JH. Heme oxygenase, carbon monoxide, and interstitial cells of Cajal. Microscopy Research & Technique. 1999 Dec 1; 47(5):321-4.
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  59. Farrugia G, Holm AN, Rich A, Sarr MG, Szurszewski JH, Rae JL. A mechanosensitive calcium channel in human intestinal smooth muscle cells. Gastroenterology. 1999 Oct; 117(4):900-5.
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  60. Xue L, Farrugia G, Sarr MG, Szurszewski JH. ATP is a mediator of the fast inhibitory junction potential in human jejunal circular smooth muscle. Am J Physiol. 1999 Jun; 276(6 Pt 1):G1373-9.
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  61. Miller SM, Schmalz PF, Benarroch EE, Szurszewski JH. Leptin receptor immunoreactivity in sympathetic prevertebral ganglion neurons of mouse and rat. Neurosci Lett. 1999 Apr 16; 265(2):75-8.
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  62. Sha L, Szurszewski JH. Leptin modulates fast synaptic transmission in dog pancreatic ganglia. Neurosci Lett. 1999 Mar 26; 263(2-3):93-6.
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  63. Miller SM, Schmelzer JD, Szurszewski JH, Benarroch EE. Distribution of leptin receptors in autonomic and motor regions of rat brain. Neurology. 1999; 52(2):A534.
  64. Sha L, Ermilov LG, He CL, Schmalz PF, Norton I, Farrugia G, Szurszewski JH. Leptin receptor immunoreactivity (OB-R IR) is present in human pancreatic ganglia. Clinical Autonomic Research. 1999; 9(4):224.
  65. Miller SM, Schmelzer JD, Schmeichel AM, Benarroch EE, Szurszewski JH. Leptin receptor-like immunoreactivity in intrinsic neurons and vagal and spinal afferent neurons innervating the stomach. Clinical Autonomic Research. 1999; 9(4):225.
  66. Ermilov LG, Szurszewski JH. PACAP27 and other neuropeptides in the inferior mesenteric ganglion. Ann N Y Acad Sci. 1998 Dec 11; (865):360-6.
  67. Skok VI, Farrugia G, Ermilov LG, Miller SM, Szurszewski JH. Patch-clamp recordings of membrane currents evoked during natural synaptic activity in sympathetic neurons. Neuroscience. 1998 Nov; 87(2):509-17.
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  68. Hanani M, Ermilov LG, Schmalz PF, Louzon V, Miller SM, Szurszewski JH. The three-dimensional structure of myenteric neurons in the guinea-pig ileum. J Auton Nerv Syst. 1998 Jun 30; 71(1):1-9.
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  69. Lu G, Mazet B, Sarr MG, Szurszewski JH. Effect of nitric oxide on calcium-activated potassium channels in colonic smooth muscle of rabbits. Am J Physiol Gastrointest Liver Physiol. 1998 May; 274(5):G 848-G 856.
  70. Hashmonai M, Szurszewski JH. Effect of cerebroventricular perfusion of bombesin on gastrointestinal myoelectric activity. Am J Physiol Gastrointest Liver Physiol. 1998 Apr; 274(4):G 677-G 686.
  71. Lu G, Sarr MG, Szurszewski JH. Effect of motilin and erythromycin on calcium-activated potassium channels in rabbit colonic myocytes. Gastroenterology. 1998 Apr; 114(4):748-54.
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  72. Szurszewski JH. A 100-year perspective on gastrointestinal motility. Am J Physiol Gastrointest Liver Physiol. 1998 Mar; 274(3):G 447-G 453.
  73. Miller SM, Farrugia G, Schmalz PF, Ermilov LG, Maines MD, Szurszewski JH. Heme oxygenase 2 is present in interstitial cell networks of the mouse small intestine. Gastroenterology. 1998 Feb; 114(2):239-44.
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  74. Farrugia G, Nitecki S, Harty GJ, Camilleri M, Szurszewski JH. The effect of flufenamic acid on gastrointestinal myoelectrical activity and transit time in dogs. Gut. 1998 Feb; 42(2):258-65.
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  75. Farrugia G, Miller SM, Rich A, Liu X, Maines MD, Rae JL, Szurszewski JH. Distribution of heme oxygenase and effects of exogenous carbon monoxide in canine jejunum. Am J Physiol. 1998 Feb; 274(2 Pt 1):G350-8.
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  76. Ermilov LG, Hanani M, Schmalz PF, Miller SM, Szurszewski JH. Distribution of nicotinic receptors in intestinofugal neurons of the guinea pig. Neurogastroenterology and Motility. 1998; 10:69.
  77. Sha L, Miller SM, Szurszewski JH. Leptin receptors are present in pancreatic ganglia. Neurogastroenterol Motil. 1998; 10:96.
  78. Ermilov LG, Szurszewski JH. Effect of PACAP-27 on the guinea pig inferior mesenteric ganglion neurons. Gastroenterology. 1998; 114:A750.
  79. Xue L, Farrugia G, Szurszewski JH. Effect of exogenous ATP on canine jejunal circular smooth muscle cells. Gastroenterology. 1998; 114:A861.
  80. Szurszewski JH. The prevertebral ganglia: mediators of gut-brain reflexes. Neurogastroenterology and Motility. 1998; 10:352.
  81. Ermilov LG, Schmalz PF, Miller SM, Szurszewski JH. Three-dimensional (3-D) morphology of guinea pig dorsal root ganglia neurons. Neurogastroenterology and Motility. 1998; 10:361.
  82. Miller SM, Schmalz PF, Benarroch E, Szurszewski JH. Leptin receptor immunoreactivity in sympathetic prevertebral ganglion neurons of mouse. Neurogastroenterology and Motility. 1998; 10:364.
  83. Sha L, Ermilov LG, Schmalz PF, Szurszewski JH. Localization of leptin receptor-like immunoreactivity in rat pancreatic ganglia. Neurogastroenterology and Motility. 1998; 10:366.
  84. Ermilov LG, Schmalz PF, Szurszewski JH. PACAP27 is a putative neuromodulator in the guinea pig inferior mesenteric ganglion. Digestive Diseases and Sciences. 1998; 43:1587.
  85. Kubota M, Suita S, Szurszewski JH. Membrane properties and the neuro-effector transmission of smooth muscle cells in the canine internal anal sphincter. Journal of Smooth Muscle Research. 1998; 34(4):173-84.
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  86. Miller SM, Ermilov LG, Szurszewski JH, Hammond PI, Brimijoin S. Selective disruption of neurotransmission by acetylcholinesterase antibodies in sympathetic ganglia examined with intracellular microelectrodes. J Auton Nerv Syst. 1997 Dec 11; 67(3):156-67.
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  87. Lu G, Sarr MG, Szurszewski JH. Effects of ethyl alcohol on canine jejunal circular smooth muscle. Dig Dis Sci. 1997 Dec; 42(12):2403-10.
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  88. Szurszewski JH. The centennial year - the development of important ideas during the last 100 years - the enigmatic electrical slow wave - a mirror on 100 years of research in gut motility. Gastroenterology. 1997 Nov; 113(5):1785-1787.
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  89. Farrugia G, Macielag MJ, Peeters TL, Sarr MG, Galdes A, Szurszewski JH. Motilin and OHM-11526 activate a calcium current in human and canine jejunal circular smooth muscle. Am J Physiol Gastrointest Liver Physiol. 1997 Aug; 273(2):G 404-G 412.
  90. Liu X, Miller SM, Szurszewski JH. Protection of nitrergic neurotransmission by and colocalization of neural nitric oxide synthase with copper zinc superoxide dismutase. J Auton Nerv Syst. 1997 Feb 17; 62(3):126-33.
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  91. Miller SM, Szurszewski JH. Colonic mechanosensory afferent input to neurons in the mouse superior mesenteric ganglion. Am J Physiol Gastrointest Liver Physiol. 1997 Feb; 272(2):G 357-G 366.
  92. Sha L, Love JA, Ma RC, Szurszewski JH. Cholinergic transmission in pancreatic ganglia of the cat. Pancreas. 1997 Jan; 14(1):83-93.
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  93. Lu G, Sarr MG, Szurszewski JH. Effect of extrinsic denervation in a canine model of jejunoileal autotransplantation on mechanical and electrical activity of jejunal circular smooth muscle. Dig Dis Sci. 1997 Jan; 42(1):40-6.
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  94. Brimijoin S, Miller SM, Ermilov L, Szurszewski JH. Synaptic transmission in sympathetic ganglia exposed to acetylcholinesterase antibodies. Journal of Autonomic Pharmacology. 1997; 17:225.
  95. Sha L, Ou LL, Miller SM, Ma R, Szurszewski JH. Cat pancreatic neurons: morphology, electrophysiological properties, and responses to 5-HT. Pancreas. 1996 Aug; 13(2):111-24.
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  96. Ma RC, Szurszewski JH. Modulation by opioid peptides of mechanosensory pathways supplying the guinea-pig inferior mesenteric ganglion. J Physiol. 1996 Mar 1; 491 ( Pt 2):435-45.
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  97. Ma RC, Szurszewski JH. Facilitating effect of CCK on nicotinic neurotransmission in cat pancreatic ganglion. Am J Physiol. 1996 Mar; 270(3 Pt 1):G526-34.
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  98. Miller SM, Hanani M, Kuntz SM, Schmalz PF, Szurszewski JH. Light, electron, and confocal microscopic study of the mouse superior mesenteric ganglion. J Comp Neurol. 1996 Feb 12; 365(3):427-444.
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  99. Ma RC, Szurszewski JH. 5-Hydroxytryptamine depolarizes neurons of cat pancreatic ganglia. J Auton Nerv Syst. 1996 Feb 5; 57(1-2):78-86.
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  100. Mazet B, Miller SM, Szurszewski JH. Electrophysiological effects of nitric oxide in mouse superior mesenteric ganglion. Am J Physiol Gastrointest Liver Physiol. 1996 Feb; 270(2):G 324-G 331.
  101. Ma RC, Szurszewski JH. Cholecystokinin depolarizes neurons of cat pancreatic ganglion. Peptides. 1996; 17(5):775-83.
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  102. Ma RC, Szurszewski JH. Release of calcitonin gene-related peptide in guinea pig inferior mesenteric ganglion. Peptides. 1996; 17(1):161-70.
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  103. Farrugia G, Rich A, Rae JL, Sarr MG, Szurszewski JH. Calcium currents in human and canine jejunal circular smooth muscle cells. Gastroenterology. 1995 Sep; 109(3):707-17.
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  104. Sha L, Miller SM, Szurszewski JH. Nitric oxide is a neuromodulator in cat pancreatic ganglia: histochemical and electrophysiological study. Neurosci Lett. 1995 Jun 9; 192(2):77-80.
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  105. Nitecki S, Harty GJ, Szurszewski JH. CCK and NPY have opposing effects on the unrestrained canine body weight. Neurogastroenterology and Motility. 1995; 7:125.
  106. Szurszewski JH. Neural control of the pancreas. The Physiologist Society Magazine. 1995; 21:15-6.
  107. Nitecki S, Karmeli R, Harty GJ, Kamei C, Yaksh TL, Szurszewski JH. Long-term perfusion of the cerebroventricular system of dogs without leakage to the peripheral circulation. Am J Physiol. 1994 Nov; 267(5 Pt 2):R1309-19.
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  108. Nitecki S, Harty GJ, Szurszewski JH. Effect of hypothalamic microinjection and ventricular perfusion of CCK receptor antagonists on gut myoelectrical activity. Ann N Y Acad Sci. 1994 Mar 23; (713):358-9.
  109. Hanani M, Ermilov L, Louzon V, Schmalz PF, Miller SM, Szurszewski JH. Three dimensional reconstruction of myenteric neurons of the guinea pig. SPIE. 1994; 2359:730-5.
  110. Liu X, Szurszewski JH. The nitrergic neurotransmitter in the rat anococcygeus muscle is protected by endogenous superoxide dismutase. Gastroenterology. 1994; 107:1230.
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  111. Parkman HP, Stapelfeldt WH, Williams CL, Lennon VA, Szurszewski JH. Enteric GABA-containing nerves projecting to the guinea-pig inferior mesenteric ganglion modulate acetylcholine release. J Physiol. 1993 Nov; 471:191-207.
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  112. Stapelfeldt WH, Parkman HP, Szurszewski JH. The electrophysiological effects of endogenous GABA in the guinea-pig inferior mesenteric ganglion. J Physiol. 1993 Nov; 471:175-89.
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  113. Farrugia G, Rae JL, Sarr MG, Szurszewski JH. Potassium current in circular smooth muscle of human jejunum activated by fenamates. Am J Physiol. 1993 Nov; 265(5 Pt 1):G873-9.
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  114. Parkman HP, Ma RC, Stapelfeldt WH, Szurszewski JH. Direct and indirect mechanosensory pathways from the colon to the inferior mesenteric ganglion. Am J Physiol. 1993 Sep; 265(3 Pt 1):G499-505.
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  115. Farrugia G, Rae JL, Szurszewski JH. Characterization of an outward potassium current in canine jejunal circular smooth muscle and its activation by fenamates. J Physiol. 1993 Aug; 468:297-310.
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  116. Farrugia G, Irons WA, Rae JL, Sarr MG, Szurszewski JH. Activation of whole cell currents in isolated human jejunal circular smooth muscle cells by carbon monoxide. Am J Physiol. 1993 Jun; 264(6 Pt 1):G1184-9.
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  117. Stark ME, Bauer AJ, Sarr MG, Szurszewski JH. Nitric oxide mediates inhibitory nerve input in human and canine jejunum. Gastroenterology. 1993; 104:398-409.
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  118. Mazet B, Miller S, Ermilov L, Szurszewski JH. Distribution of NADPH-diaphorase in abdominal prevertebral ganglia. Journal of Gastrointestinal Motility. 1993; 5:204.
  119. Miller S, Hanani M, Schmalz P, Szurszewski JH. Three-dimensional reconstruction of VIP innervation of smooth muscle of the mouse large intestine. Journal of Gastrointestinal Motility. 1993; 5:206.
  120. Nitecki S, Harty GJ, Szurszewski JH. CCK A receptors in the canine brain modulate gastrointestinal myoelectrical activity. Journal of Gastrointestinal Motility. 1993; 5:208.
  121. Stark ME, Szurszewski JH. Role of nitric oxide in gastrointestinal and hepatic function and disease. Gastroenterology. 1992 Dec; 103(6):1928-49.
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  122. Stapelfeldt WH, Szurszewski JH. Capsaicin pretreatment attenuates propofol-induced hemodynamic effects in anesthetized guinea pigs. Anesth Analg. 1992; 74:S305.
  123. Miller S, Brewer J, Tarara J, Schmalz P, Szurszewski JH. 3-D reconstruction of abdominal prevertebral ganglion neurons. Gastroenterology. 1992; 102:A486.
  124. Rozsa Z, Berseth CL, Szurszewski JH. Capsaicin sensitive afferent nerves influence postnatal development of canine duodenal motor activity. Gastroenterology. 1992; 102:A576.
  125. Ma RC, Szurszewski JH. 5-hydroxytryptamine (5-HT) evokes fast and slow depolarization in cat intrapancreatic neurons. Gastroenterology. 1992; 102:A744.
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  126. Szurszewski JH. Enteric nervous system and interactions with sympathetic ganglia. Digestive Diseases and Sciences. 1992; 37:970.
  127. Ermilov LG, Miller SM, Schmalz PF, Tarara J, Szurszewski JH. Morphology of neurons in guinea pig peripheral autonomic ganglia revealed by intracellular injection of fluorescent dye. Gastroenterology. 1992; 103:1389.
  128. Miller SM, Schmalz P, Ermilov L, Tarara J, Ma R, Brewer J, Szurszewski JH. Three-dimensional structure of neurons from peripheral autonomic ganglia using confocal microscopic images. SPIE Proceedings. 1992; 1808:640-50.
  129. Stark ME, Bauer AJ, Szurszewski JH. Effect of nitric oxide on circular muscle of the canine small intestine. J Physiol. 1991 Dec; 444:743-61.
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  130. Bauer AJ, Sarr MG, Szurszewski JH. Opioids inhibit neuromuscular transmission in circular muscle human and baboon jejunum. Gastroenterology. 1991 Oct; 101:970-976.
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  131. Ma RC, Szurszewski JH. Release of calcitonin gene-related peptide in guinea pig inferior mesenteric ganglion during colonic distension. J Auton Nerv Syst. 1991 Jun; 33:118-119.
  132. Koch TR, Carney JA, Go VL, Szurszewski JH. Inhibitory neuropeptides and intrinsic inhibitory innervation of descending human colon. Dig Dis Sci. 1991 Jun; 36(6):712-8.
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  133. Bauer AJ, Szurszewski JH. Effect of opioid peptides on circular muscle of canine duodenum. J Physiol. 1991 Mar; 434:409-22.
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  134. Bauer AJ, Hanani M, Muir TC, Szurszewski JH. Intracellular recordings from gallbladder ganglia of opossums. Am J Physiol. 1991 Feb; 260(2 Pt 1):G299-306.
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  135. Ma RC, Roddy DR, Nelson DK, Szurszewski JH. Subtype of opioid receptors mediating the inhibitory effect of enkephalin (ENK) on release of CGRP in guinea pig inferior mesenteric ganglion (IMG) during colonic distension. FASEB Journal. 1991; 5:4952.
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  136. Yamanaka K, Sulta S, Szurszewski JH. Development of intramural innervation of the pyloric circular muscle of new-born dogs. Journal of Gastrointestinal Motility. 1991; 3:208.
  137. Koch TR, Carney JA, Go VL, Szurszewski JH. Altered inhibitory innervation of circular smooth muscle in Crohn's colitis. Association with decreased vasoactive intestinal polypeptide levels. Gastroenterology. 1990 Jun; 98(6):1437-44.
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  138. Parkman HP, Stapelfeldt WH, Szurszewski JH. Peripheral GABA-containing nerves projecting to the inferior mesenteric ganglion selectively facilitate colonic afferent cholinergic input. Gastroenterology. 1990; 98:A379.
  139. Bauer AJ, Szurszewski JH. Cholinergic modulation of human gastric smooth muscle. Gastroenterology. 1990; 99:1203.
  140. Castell DO, Blankenbaker RG, Bozymski EM, Bulkley GB, Elashoff JD, Galambos JT, Harmon JW, Knauer CM, Krishnamurthy S, Moser RH, Ransohoff DF, Russell RM, Sampliner RE, Scott IG, Szurszewski JH. Consensus statement on therapeutic endoscopy and bleeding ulcers. Gastrointestinal Endoscopy Supplement. 1990; 36:S62-5.
  141. King BF, Love JA, Szurszewski JH. Intracellular recordings from pancreatic ganglia of the cat. J Physiol. 1989 Dec; 419:379-403.
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  142. Szurszewski JH, Holt PR, Schuster M. Proceedings of a workshop entitled "Neuromuscular function and dysfunction of the gastrointestinal tract in aging". Dig Dis Sci. 1989 Jul; 34(7):1135-46.
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  143. Stapelfeldt WH, Szurszewski JH. The electrophysiological effects of neurotensin on neurones of guinea-pig prevertebral sympathetic ganglia. J Physiol. 1989 Apr; 411:301-23.
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  144. Stapelfeldt WH, Szurszewski JH. Neurotensin facilitates release of substance P in the guinea-pig inferior mesenteric ganglion. J Physiol. 1989 Apr; 411:325-45.
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  145. Stapelfeldt WH, Szurszewski JH. Central neurotensin nerves modulate colo-colonic reflex activity in the guinea-pig inferior mesenteric ganglion. J Physiol. 1989 Apr; 411:347-65.
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  146. King BF, Szurszewski JH. Peripheral reflex pathways involving abdominal viscera: transmission of impulses through prevertebral ganglia. Am J Physiol. 1989 Mar; 256(3 Pt 1):G581-8.
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  147. Telford GL, Condon RE, Szurszewski JH. Opioid receptors and the initiation of migrating myoelectric complexes in dog. Am J Physiol. 1989 Jan; 256(1):672-77.
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  148. Bauer AJ, Szurszewski JH. Dynorphin presynaptically inhibits neuromuscular transmission via an opioid receptor in circular muscle of canine duodenum. Gastroenterology. 1989; 96:A33.
  149. Miller SM, Szurszewski JH. Evidence that colonic mechanoreceptors function as volume receptors. Gastroenterology. 1989; 96:A345.
  150. Yamanaka K, Szurszewski JH. Electrophysiological effects of neurotensin on human gastric antrum. Gastroenterology. 1989; 96:A555.
  151. Yamanaka K, Telander RL, Szurszewski JH. Electrophysiological characteristics of human pyloric circular smooth muscle of patients with idiopathic hypertrophic pyloric stenosis. Journal of Gastrointestinal Motility. 1989; 1:76.
  152. Hashmonai J, Szurszewski JH. Effect of brain perfusion on bombesin on myoelectrical activity of the canine GI tract. Journal of Gastrointestinal Motility. 1989; 1:76.
  153. Miller SM, Szurszewski JH. Colonic mechanoreceptors projecting to mouse prevertebral ganglia function as volume receptors. Journal of Gastrointestinal Motility. 1989; 1:79.


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