Publications - Brian R . Younge, M.D.

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1. Elmalem VI, Younge BR, Biousse V, Leavitt JA, Moster ML, Warner J, Kupersmith MJ, Landau K, Brodsky MC, Frohman LP, May EF, Tomsak RL, Newman NJ. Clinical course and prognosis of trochlear nerve schwannomas. Ophthalmology 2009 Oct; 116(10):2011-6.
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2. Milone M, Younge BR, Wang J, Zhang S, Wong LJ. Mitochondrial disorder with OPA1 mutation lacking optic atrophy. Mitochondrion 2009 Jul; 9(4):279-81. Epub 2009 Mar 20.
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3. Kosa SC, Younge BR, Kumar N. Headaches due to giant cell arteritis following herpes zoster ophthalmicus in an elderly patient. Cephalalgia 2009 Apr 30. [Epub ahead of print]
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4. Weyand CM, Younge BR, Goronzy JJ. T cells in arteritis and atherosclerosis. Curr Opin Lipidol 2008 Oct; 19(5):469-77.
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5. Pryshchep O, Ma-Krupa W, Younge BR, Goronzy JJ, Weyand CM. Vessel-specific Toll-like receptor profiles in human medium and large arteries. Circulation 2008 Sep 16; 118(12):1276-84.
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6. Younge BR, McLaren JW, Brown WL. Retinal image stability in head tremor and nystagmus: counterintuitive observations. J Neuroophthalmol 2007 Jun; 27(2):107-14.
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7. Qian Q, Younge BR, Torres VE. Retinal arterial and venous occlusions in patients with ADPKD. Nephrol Dial Transplant 2007 Jun; 22(6):1769-71. Epub 2007 Apr 01.
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8. Younge BR, Weyand CM, Goronzy JJ. Occurrence of giant cell arteritis...suddenly. Trans Am Ophthalmol Soc 2007; 105:141-4; discussion 144-5.
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9. Mazlumzadeh M, Hunder GG, Easley KA, Calamia KT, Matteson EL, Griffing WL, Younge BR, Weyand CM, Goronzy JJ. Treatment of giant cell arteritis using induction therapy with high-dose glucocorticoids: a double-blind, placebo-controlled, randomized prospective clinical trial. Arthritis Rheum 2006 Oct; 54(10):3310-8.
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10. Feldon SE, Levin L, Scherer RW, Arnold A, Chung SM, Johnson LN, Kosmorsky G, Newman SA, Katz J, Langenberg P, Wilson PD, Kelman SE, Dickersin K, Kennerdell J, Bruchis A, Govreau D, Holds J, Selhorst J, Malton M, Rogers A, Saunders T, King K, Fecko T, Development and validation of a computerized expert system for evaluation of automated visual fields from the Ischemic Optic Neuropathy Decompression Trial. BMC Ophthalmology 2006; 6.
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11. Ramakrishna G, Malouf JF, Younge BR, Connolly HM, Miller FA. Calcific retinal embolism as an indicator of severe unrecognised cardiovascular disease. Heart (British Cardiac Society) 2005 Sep; 91(9):1154-7.
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12. Peterson DC, Inwards DJ, Younge BR. Oprelvekin-associated bilateral optic disk edema. Am J Ophthalmol 2005 Feb; 139(2):367-8.
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13. Peterson DC, Inwards, Younge BR. Oprelvekin-associated bilateral optic disc edema. Am J Ophthalmol July 2004.
14. Younge BR, Cook BE, Bartley GB, Hodge DO, Hunder GG. Initiation of glucocorticoid therapy: Before or after temporal artery biopsy? Mayo Clin Proc 2004 Apr; 79(4):483-91.
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15. Younge BR, Khabie N, Brey RH, Driscoll CL. Rotatory nystagmus synchronous with heartbeat: a treatable form of nystagmus. Trans Am Ophthalmol Soc 2003; 101:113-7; discussion 117-8.
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16. Krupa WM, Dewan M, Jeon MS, Kurtin PJ, Younge BR, Goronzy JJ, Weyand CM. Trapping of misdirected dendritic cells in the granulomatous lesions of giant cell arteritis. Am J Pathol 2002 Nov; 161(5):1815-23.
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17. Borkowski A, Younge BR, Szweda L, Mock B, Bjornsson J, Moeller K, Goronzy JJ, Weyand CM. Reactive nitrogen intermediates in giant cell arteritis - Selective nitration of neocapillaries. Am J Pathol 2002 Jul; 161(1):115-23.
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18. Weyand CM, Kaiser M, Yang HY, Younge B, Goronzy JJ. Therapeutic effects of acetylsalicylic acid in giant cell arteritis. Arthritis Rheum 2002 Feb; 46(2):457-66.
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19. Petty GW, Matteson EL, Younge BR, McDonald TJ, Wood CP. Recurrence of susac syndrome (retinocochleocerebral vasculopathy) after remission of 18 years. Mayo Clin Proc 2001 Sep; 76(9):958-60.
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20. Norman ME, Albertson D, Younge BR. Ophthalmic manifestations of lightning strike. Surv Ophthalmol 2001 Jul-Aug; 46(1):19-24.
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21. Younge BR. Iatrogenic hysterical visual loss: a neuro-ophthalmologist's nightmare. Emedicine 2001.
22. Ischemic Optic Neuropathy Decompression Trial Research Group. Ischemic optic neuropathy decompression trial: twenty-four month update. Arch Ophthalmol June 2000; 118:793-798.
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23. Younge B. Anterior ischemic opitc neuropathy. Emedicine, Ophthalmology 2000.
24. Lawn ND, Wijdicks EF, Younge BR. A blinding headache and two black eyes. Journal of Neurology, Neurosurgery & Psychiatry 1999 Aug; 67(2):246-7.
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25. Norman ME, Younge BR. Association of high-dose intravenous methylprednisolone with reversal of blindness from lightning in two patients. Ophthalmology 1999 Apr; 106(4):743-5.
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26. Kaiser M, Younge B, Bjornsson JJ, Weyand CM: Formation of new vasa vasorum in vasculitis. Production of angiogenic cytokines by multinucleated giant cells. Am J of Path 1999; 3:765-774.
27. Petty GW, Engel AG, Younge BR, Duffy J, Yanagihara T, Lucchinetti CF, Bartleson JD, Parisi JE, Kasperbauer JL, Rodriguez M. Retinocochleocerebral vasculopathy. Medicine (Baltimore) 1998 Jan; 77(1):12-40.
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28. Brack A, Geisler A, Martinez-Taboada VM, Younge BR, Goronzy JJ, Weyand CM. Giant cell vasculitis is a T cell-dependent disease. Mol Med 1997 Aug; 3(8):530-43.
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29. Brack A, Rittner HL, Younge BR, Kaltschmidt C, Weyand CM, Goronzy JJ. Glucocorticoid-mediated repression of cytokine gene transcription in human arteritis-SCID chimeras. J Clin Invest 1997 Jun 15; 99(12):2842-50.
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30. Ing EB, Woolf IZ, Younge BR, Bjornsson J, Leavitt JA. Systemic amyloidosis with temporal artery involvement mimicking temporal arteritis. Ophthalmic Surgery & Lasers 1997 Apr; 28(4):328-31.
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31. Weyand CM, Tetzlaff N, Bjornsson J, Brack A, Younge B, Goronzy JJ. Disease patterns and tissue cytokine profiles in giant cell arteritis. Arthritis Rheum 1997 Jan; 40(1):19-26.
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32. Mutyala S, Holmes JM, Hodge DO, Younge BR. Spontaneous recovery rate in traumatic sixth-nerve palsy. Am J Ophthalmol 1996 Dec; 122(6):898-9.
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33. Sitenga GL, Ing EB, Van Dellen RG, Younge BR, Leavitt JA. Asthma caused by topical application of ketorolac. Ophthalmology 1996 Jun; 103(6):890-2.
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34. Ing EB, Leavitt JA, Younge BR. Papilledema following bowtie optic atrophy. Arch Ophthalmol 1996 Mar; 114(3):356-7.
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35. Kelman S, Leavitt J, Ischemic Optic Neuropathy Decompression Trial Research Group. Characteristics of patients with nonarteritic anterior ischemic optic neuropathy eligible for the Ischemic Optic Neuropathy Decompression Trial. Arch Ophthalmol 1996; 114:1366-74.
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36. Arnold RW, Armitage MD, Rosen CE, Younge BR. Head tilt due to null-point seesaw nystagmus. Am J of Orthoptics 1996; 46:181-4.
37. Ing EB, Younge BR, Leavitt JA, Fitzpatrick PJ. Functional visual loss and the duochrome rest. Can J Ophthalmol 1995 Feb; 30:35-36.
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38. Ing EB, Younge BR, Leavitt JA, Lee RA, Bostwick DG. Paraneoplastic retinopathy and gynecologic malignancy. Journal of Pelvic Surgery 1995; 1:79-83.
39. Ischemic Optic Neuropathy Decompression Trial Research Group. Optic nerve decompression surgery for nonarteritic anterior ischemic optic neuropathy (NAION) is not effective and may be harmful. The Ischemic Optic Neuropathy Decompression Trial Research Group. JAMA 1995; 273(8):625-632.
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40. Garcia EG, Wijdicks EF, Younge BR. Neurologic complications associated with internal jugular vein cannulation in critically ill patients: a prospective study. Neurology 1994 May; 44(5):951-2.
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41. Kodsi SR, Younge BR, Leavitt JA, Campbell RJ, Scheithauer BW. Intracranial plasma cell granuloma presenting as an optic neuropathy. Surv Ophthalmol 1993 Jul-Aug; 38(1):70-4.
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42. Kodsi SR, Younge BR. The four-meter confrontation visual field test. J Clin Neuroophthalmol 1993 Mar; 13(1):40-3.
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43. Kodsi S, Younge BR. Acquired oculomotor, trochlear, and abducent palsies in pediatric patients. Am J Ophthalmol 1993; 114:568-74.
44. Richards BW, Jones FR Jr, Younge BR. Causes and prognosis in 4,278 cases of paralysis of the oculomotor, trochlear, and abducens cranial nerves. Am J Ophthalmol 1992 May 15; 113(5):489-96.
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45. Bartley GB, Younge BR. Stereoscopic external photography and the free stereo technique. Ophthalmic Plast Reconstr Surg 1991; 7(1):67-8.
46. Baker RH, Trautmann JC, Younge BR, Nelson KD, Zimmerman D. Late juvenile-onset Krabbe's disease. Ophthalmology 1990 Sep; 97(9):1176-80.
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47. Younge BR. The significance of retinal emboli. J of Clin Neuro-ophthalmology 9(3), 19-194, 1989.
48. Rivera RP, Younge BR, Dyer JA. Atypical amiodarone-induced keratopathy in a patient wearing soft contact lenses. The CLAO Journal 15(3), 219-221, 1989.
49. Younge BR. 1st Annual Sean B.Murphy Lecture: Aerospace Medicine and Neuro-ophthalmology. McGill Ophthalmology 1(4), 13-14, 1989.
50. Feiner LA, Younge BR, Kazmier FJ, Stricker BH, Fraunfelder FT. Optic neuropathy and amiodarone therapy. Mayo Clin Proc 1987 Aug; 62(8):702-17.
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51. Wilson WB, Lloyd LA, Buncic JR, Younge BR, Grimson BS, Shults WT, Lubow M, Slamovitis TL, Wirtschafter JD, Kupersmith M, Lessell S. Tumor spread in unilateral optic glioma - I. Neuroophthalmology 1987; 7:179-184.
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52. Vollertsen RS, McDonald TJ, Younge BR, Banks PM, Stanson AW, Ilstrup DM. Cogan's syndrome: 18 cases and a review of the literature. Mayo Clin Proc 1986 May; 61(5):344-61.
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53. McDonald TJ, Vollertsen RS, Younge BR. Cogan's syndrome: audiovestibular involvement and prognosis in 18 patients. Laryngoscope 1985 Jun; 95(6):650-4.
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54. Younge BR. Computer-assisted perimetry in visual pathway disease: neuro-ophthalmic applications. Trans Am Ophthalmol Soc 1984; 82:899-942.
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55. van Meter WS, Younge BR, Harner SG. Ophthalmic manifestations of acoustic neurinoma. Ophthalmology 1983 Aug; 90(8):917-22.
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56. Bullen CL, Younge BR. Chronic orbital myositis. Arch Ophthalmol 1982 Nov; 100(11):1749-51.
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57. Rush JA, Younge BR, Campbell RJ, MacCarty CS. Optic glioma. Long-term follow-up of 85 histopathologically verified cases. Ophthalmology 1982 Nov; 89(11):1213-9.
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58. Wiebers DO, Folger WN, Forbes GS, Younge BR, O'Fallon WM. Ophthalmodynamometry and ocular pneumoplethysmography for detection of carotid occlusive disease. Arch Neurol 1982 Nov; 39(11):690-1.
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59. Kelly JJ, Daube JR, Lennon VA, Howard FM, Younge BR. The laboratory diagnosis of mild myasthenia gravis. Ann Neurol 1982 Sep; 12(3):238-42.
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60. Swenson SA, Forbes GS, Younge BR, Campbell RJ. Radiologic evaluation of tumors of the optic nerve. AJNR Am J Neuroradiol 1982 May-Jun; 3(3):319-26.
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61. Wiebers DO, Folger WN, Younge BR. Ocular pneumoplethysmography and ophthalmodynamometry in the diagnosis of central retinal artery occlusion. Stroke 1982 May-Jun; 13(3):379-81.
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62. Wirtschafter JD, Becker WL, Howe JB, Younge BR. Glaucoma visual field analysis by computed profile of nerve fiber function in optic disc sectors. Ophthalmology 1982 Mar; 89(3):255-67.
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63. Tenny RT, Laws ER Jr, Younge BR, Rush JA. The neurosurgical management of optic glioma: Results in 110 patients. J of Neurosurg , Oct 1982; 57:452-8.
64. Palestine AG, Younge BR, Piepgras DG. Carotid-cavernous fistula, a review of 76 cases at the Mayo Clinic. Arch Ophthalmol 1981 Sep; 99.
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65. Samples JR, Younge BR. Tobacco-alcohol amblyopia. J Clin Neuroophthalmol 1981 Sep; 1(3):213-8.
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66. Palestine AG, Younge BR, Piepgras DG. Visual prognosis in carotid-cavernous fistula. Arch Ophthalmol 1981 Sep; 99(9):1600-3.
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67. Rush JA, Younge BR. Paralysis of cranial nerves III, IV, and VI. Cause and prognosis in 1,000 cases. Arch Ophthalmol 1981 Jan; 99(1):76-9.
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68. Maloney WF, Younge BR, Moyer NJ. Evaluation of the causes and accuracy of pharmacological localization in Horner's syndrome. Am J Ophthalmol 1980 Sep; 90:394-402.
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69. Younge BR, Waller RR. Complications of transantral orbital decompression for the treatment of Graves' ophthalmopathy. (Program supplement). Ophthalmology 1980 Aug; 87(Suppl TO NO. 8):80.
70. Kearns TP, Younge BR, Piepgras DG. Resolution of venous stasis retinopathy after carotid artery bypass surgery. Mayo Clin Proc 1980 May; 55(5):342-6.
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71. Younge BR, Trautmann JC. Computer-assisted perimetry in neuro-ophthalmic disease. Mayo Clin Proc 1980 Apr; 55(4):207-22.
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72. Walsh TJ, Wirtschafter JD, Drance SM, Younge BR, Hedges TR. The interpretation of visual fields: a manual. American Academy of Ophthalmology, 1979.
73. Younge BR, Rosenbaum TJ. Treatment of acute central retinal artery occlusion. Mayo Clin Proc 1978 Jun; 53(6):408-10.
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74. Sheremata W, Younge BR, Eylar EH. Retrobular neuritis. In vitro evidence of sensitization to myelin basic protein in patients without multiple sclerosis. Neurology 1977 Jun; 27:557-560.
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75. Younge BR, Sutula F. Analysis of trochlear nerve palsies. Diagnosis, etiology, and treatment. Mayo Clin Proc 1977 Jan; 52(1):11-8.
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76. Younge BR, Buski ZJ. Tonic pupil: a simple screening test. Can J Ophthalmol 1976 Oct; 11(4):295-9.
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77. Younge BR. Midline tilting between seeing and nonseeing areas in hemianopia. Mayo Clin Proc 1976 Sep; 51(9):562-8.
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78. Katsarkas A, Younge BR. Electronystagmographic findings in cerebellar dysfunction. J Otolaryngol 1976 Apr; 5(2):143-53.
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79. Younge BR. Fluorescein angiography and retinal venous sheathing in multiple sclerosis. Canad J Ophthalmol , 1976; 11:31-6.
80. Hollenhorst RW, Younge BR. Ocular manifestations produced by adenomas of the pituitary gland: analysis of 1000 cases. Int Congr Ser 1973; 303:53-64.