Publications - Johannes D . Veldhuis, M.D.

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1. Hudson SB, Schroeder DR, Bailey JN, Mielke KL, Erickson D, Miles JM, Bowers CY, Veldhuis JD. Pre- Versus Postmenopausal Age, Estradiol, and Peptide-Secretagogue Type Determine Pulsatile Growth Hormone Secretion in Healthy Women: Studies Using Submaximal Agonist Drive and an Estrogen Clamp. J Clin Endocrinol Metab 2009 Oct 26. [Epub ahead of print]
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2. Roelfsema F, Pereira AM, Veldhuis JD, Adriaanse R, Endert E, Fliers E, Romijn JA. Thyrotropin secretion profiles are not different in men and women. J Clin Endocrinol Metab 2009 Oct; 94(10):3964-7. Epub 2009 Sep 22.
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3. Veldhuis JD, Roelfsema F, Iranmanesh A, Carroll BJ, Keenan DM, Pincus SM. Basal, pulsatile, entropic (patterned), and spiky (staccato-like) properties of ACTH secretion: impact of age, gender, and body mass index. J Clin Endocrinol Metab 2009 Oct; 94(10):4045-52. Epub 2009 Sep 15.
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4. Liu PY, Takahashi PY, Roebuck PD, Bailey JN, Keenan DM, Veldhuis JD. Testosterone's short-term positive effect on luteinizing-hormone secretory-burst mass and its negative effect on secretory-burst frequency are attenuated in middle-aged men. J Clin Endocrinol Metab 2009 Oct; 94(10):3978-86. Epub 2009 Jul 07.
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5. Ropelato MG, Rudaz MC, Escobar ME, Bengolea SV, Calcagno ML, Veldhuis JD, Barontini M. Acute effects of testosterone infusion on the serum luteinizing hormone profile in eumenorrheic and polycystic ovary syndrome adolescents. J Clin Endocrinol Metab 2009 Sep; 94(9):3602-10. Epub 2009 Jun 30.
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6. Ropelato MG, Rudaz MCG, Escobar ME, Bengolea SV, Calcagno ML, Veldhuis JD, Barontini M. Acute effects of testosterone infusion on the serum luteinizing hormone profile in eumenorrheic and polycystic ovary syndrome adolescents. J Clin Endocrinol Metab 2009 Sep; 94(9):3602-10.
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7. Roelfsema F, Kok S, Kok P, Pereira AM, Biermasz NR, Smit JW, Frolich M, Keenan DM, Veldhuis JD, Romijn JA. Pituitary-hormone secretion by thyrotropinomas. Pituitary 2009 Sep; 12(3):200-10.
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8. Keenan DM, Roelfsema F, Carroll BJ, Iranmanesh A, Veldhuis JD. Sex defines the age dependence of endogenous ACTH-cortisol dose responsiveness. Am J Physiol Regul Integr Comp Physiol 2009 Aug; 297(2):R515-23.
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9. Liu PY, Keenan DM, Kok P, Padmanabhan V, O'Byrne KT, Veldhuis JD. Sensitivity and specificity of pulse detection using a new deconvolution method. Am J Physiol Endocrinol Metab 2009 Aug; 297(2):E538-44. Epub 2009 Jun 16.
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10. Veldhuis JD, Hudson SA, Bailey JN, Erickson D. Regulation of basal, pulsatile, and entropic (patterned) modes of GH secretion in a putatively low-somatostatin milieu in women. Am J Physiol Endocrinol Metab 2009 Aug; 297(2):E483-9. Epub 2009 Jun 02.
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11. Veldhuis JD, Hudson SB, Erickson D, Bailey JN, Reynolds GA, Bowers CY. Relative effects of estrogen, age, and visceral fat on pulsatile growth hormone secretion in healthy women. Am J Physiol Endocrinol Metab 2009 Aug; 297(2):E367-74. Epub 2009 May 26.
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12. Veldhuis JD, Keenan DM, Bailey JN, Miles JM, Bowers CY. Preservation of GHRH and GH-releasing peptide-2 efficacy in young men with experimentally induced hypogonadism. Eur J Endocrinol 2009 Aug; 161(2):293-300. Epub 2009 May 20.
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13. Veldhuis JD, Bowers CY. Factors other than sex steroids modulate GHRH and GHRP-2 efficacies in men: evaluation using a GnRH agonist/testosterone clamp. J Clin Endocrinol Metab 2009 Jul; 94(7):2544-50. Epub 2009 Apr 07.
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14. Ropelato MG, Garcia Rudaz MC, Escobar ME, Bengolea SV, Calcagno ML, Veldhuis JD, Barontini M. Acute effects of testosterone infusion on the serum luteinizing hormone profile in eumenorrheic and polycystic ovary syndrome adolescents. J Clin Endocrinol Metab 2009 Jun 30. [Epub ahead of print]
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15. Veldhuis JD, Keenan DM, Bailey JN, Adeniji AM, Miles JM, Bowers CY. Novel relationships of age, visceral adiposity, insulin-like growth factor (IGF)-I and IGF binding protein concentrations to growth hormone (GH) releasing-hormone and GH releasing-peptide efficacies in men during experimental hypogonadal clamp. J Clin Endocrinol Metab 2009 Jun; 94(6):2137-43. Epub 2009 Apr 07.
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16. Roelfsema F, Biermasz NR, Frolich M, Keenan DM, Veldhuis JD, Romijn JA. Diminished and irregular thyrotropin secretion with preserved diurnal rhythm in patients with active acromegaly. J Clin Endocrinol Metab 2009 Jun; 94(6):1945-50.
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17. Roelfsema F, Biermasz NR, Frolich M, Keenan DM, Veldhuis JD, Romijn JA. Diminished and irregular thyrotropin secretion with preserved diurnal rhythm in patients with active acromegaly. J Clin Endocrinol Metab 2009 Jun; 94(6):1945-50. Epub 2009 Mar 31.
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18. Veldhuis JD, Bowers CY. Determinants of GH-releasing hormone and GH-releasing peptide synergy in men. Am J Physiol Endocrinol Metab 2009 May; 296(5):E1085-92. Epub 2009 Feb 24.
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19. Keenan DM, Alexander S, Irvine C, Veldhuis JD. Quantifying nonlinear interactions within the hypothalamo-pituitary-adrenal axis in the conscious horse. Endocrinology 2009 Apr; 150(4):1941-51. Epub 2008 Nov 20.
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20. Veldhuis JD, Mielke KL, Cosma M, Soares-Welch C, Paulo R, Miles JM, Bowers CY. Aromatase and 5alpha-reductase inhibition during an exogenous testosterone clamp unveils selective sex steroid modulation of somatostatin and growth hormone secretagogue actions in healthy older men. J Clin Endocrinol Metab 2009 Mar; 94(3):973-81. Epub 2008 Dec 16.
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21. Veldhuis JD, Keenan DM, Liu PY, Iranmanesh A, Takahashi PY, Nehra AX. The aging male hypothalamic-pituitary-gonadal axis: pulsatility and feedback. Mol Cell Endocrinol 2009 Feb 5; 299(1):14-22. Epub 2008 Sep 17.
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22. Veldhuis JD, Keenan DM, Bailey JN, Adeniji A, Miles JM, Paulo R, Cosma M, Soares-Welch C. Testosterone supplementation in older men restrains insulin-like growth factor's dose-dependent feedback inhibition of pulsatile growth hormone secretion. J Clin Endocrinol Metab 2009 Jan; 94(1):246-54. Epub 2008 Nov 04.
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23. Veldhuis JD, Keenan DM, Pincus SM. Motivations and methods for analyzing pulsatile hormone secretion. Endocr Rev 2008 Dec; 29(7):823-64. Epub 2008 Oct 21.
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24. Paulo RC, Brundage R, Cosma M, Mielke KL, Bowers CY, Veldhuis JD. Estrogen elevates the peak overnight production rate of acylated ghrelin. J Clin Endocrinol Metab 2008 Nov; 93(11):4440-7. Epub 2008 Aug 12.
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25. Veldhuis JD, Keenan DM, Bailey JN, Adeniji A, Miles JM, Paulo R, Cosma M, Soares-Welch C. Estradiol supplementation in postmenopausal women attenuates suppression of pulsatile growth hormone secretion by recombinant human insulin-like growth factor type I. J Clin Endocrinol Metab 2008 Nov; 93(11):4471-8. Epub 2008 Aug 26.
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26. Veldhuis JD, Keenan DM. Secretagogues govern GH secretory-burst waveform and mass in healthy eugonadal and short-term hypogonadal men. Eur J Endocrinol 2008 Nov; 159(5):547-54. Epub 2008 Aug 14.
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27. Iranmanesh A, Veldhuis JD. Hypocortisolemic clamp unmasks jointly feedforward- and feedback-dependent control of overnight ACTH secretion. Eur J Endocrinol 2008 Nov; 159(5):561-8. Epub 2008 Aug 19.
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28. Kok P, Paulo RC, Cosma M, Mielke KL, Miles JM, Bowers CY, Veldhuis JD. Estrogen supplementation selectively enhances hypothalamo-pituitary sensitivity to ghrelin in postmenopausal women. J Clin Endocrinol Metab 2008 Oct; 93(10):4020-6. Epub 2008 Jul 08.
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29. Matveyenko AV, Veldhuis JD, Butler PC. Adaptations in pulsatile insulin secretion, hepatic insulin clearance, and beta-cell mass to age-related insulin resistance in rats. Am J Physiol Endocrinol Metab 2008 Oct; 295(4):E832-41. Epub 2008 Jul 29.
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30. Roelfsema F, Pereira AM, Keenan DM, Veldhuis JD, Romijn JA. Thyrotropin secretion by thyrotropinomas is characterized by increased pulse frequency, delayed diurnal rhythm, enhanced basal secretion, spikiness, and disorderliness. J Clin Endocrinol Metab 2008 Oct; 93(10):4052-7. Epub 2008 Aug 05.
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31. Roelfsema F, Pereira AM, Keenan DM, Veldhuis JD, Romijn JA. Thyrotropin secretion by thyrotropinomas is characterized by increased pulse frequency, delayed diurnal rhythm, enhanced basal secretion, spikiness, and disorderliness. J Clin Endocrinol Metab 2008 Oct; 93(10):4052-7. Epub 2008 Aug 05.
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32. Matveyenko AV, Veldhuis JD, Butler PC. Adaptations in pulsatile insulin secretion, hepatic insulin clearance, and beta-cell mass to age-related insulin resistance in rats. Am J Physiol Endocrinol Metab 2008 Oct; 295(4):E832-41. Epub 2008 Jul 29.
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33. Veldhuis JD, Keenan DM, Liu PY, Iranmanesh A, Takahashi PY, Nehra AX. The aging male hypothalamic-pituitary-gonadal axis: Pulsatility and Feedback. Molecular Cell Endocrinology 2008 Sept 17.
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34. Veldhuis JD, Reynolds GA, Iranmanesh A, Bowers CY. Twenty-four hour continuous ghrelin infusion augments physiologically pulsatile, nycthemeral, and entropic (feedback-regulated) modes of growth hormone secretion. J Clin Endocrinol Metab 2008 Sep; 93(9):3597-603. Epub 2008 Jul 01.
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35. Matveyenko AV, Veldhuis JD, Butler PC. Measurement of pulsatile insulin secretion in the rat: direct sampling from the hepatic portal vein. American Journal of Physiology - Endocrinology & Metabolism 2008 Sep; 295(3):E569-74.
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36. Matveyenko AV, Veldhuis JD, Butler PC. Measurement of pulsatile insulin secretion in the rat: direct sampling from the hepatic portal vein. Am J Physiol Endocrinol Metab 2008 Sep; 295(3):E569-74. Epub 2008 Jun 24.
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37. Veldhuis JD. Aging and hormones of the hypothalamo-pituitary axis: gonadotropic axis in men and somatotropic axes in men and women. Ageing Res Rev 2008 Jul; 7(3):189-208. Epub 2008 Jan 05.
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38. Aksglaede L, Jensen RB, Carlsen E, Kok P, Keenan DM, Veldhuis J, Skakkebaek NE, Juul A. Increased basal and pulsatile secretion of FSH and LH in young men with 47,XXY or 46,XX karyotypes. Eur J Endocrinol 2008 Jun; 158(6):803-10. Epub 2008 Mar 05.
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39. Waters DL, Qualls CR, Dorin RI, Veldhuis JD, Baumgartner RN. Altered growth hormone, cortisol, and leptin secretion in healthy elderly persons with sarcopenia and mixed body composition phenotypes. J Gerontol A Biol Sci Med Sci 2008 May; 63(5):536-41.
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40. Cosma M, Bailey J, Miles JM, Bowers CY, Veldhuis JD. Pituitary and/or peripheral estrogen-receptor alpha regulates follicle-stimulating hormone secretion, whereas central estrogenic pathways direct growth hormone and prolactin secretion in postmenopausal women. J Clin Endocrinol Metab 2008 Mar; 93(3):951-8. Epub 2007 Dec 18.
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41. Paulo RC, Cosma M, Soares-Welch C, Bailey JN, Mielke KL, Miles JM, Bowers CY, Veldhuis JD. Gonadal status and body mass index jointly determine growth hormone (GH)-releasing hormone/GH-releasing peptide synergy in healthy men. J Clin Endocrinol Metab 2008 Mar; 93(3):944-50. Epub 2007 Dec 11.
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42. Natesampillai S, Kerkvliet J, Leung PC, Veldhuis JD. Regulation of Kruppel-like factor 4, 9, and 13 genes and the steroidogenic genes LDLR, StAR, and CYP11A in ovarian granulosa cells. Am J Physiol Endocrinol Metab 2008 Feb; 294(2):E385-91. Epub 2007 Dec 04.
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43. Bowers CY, Merriam GR, Veldhuis JD. Validation of growth-hormone-releasing peptide 2 for the diagnosis of adult growth hormone deficiency. Nat Clin Pract Endocrinol Metab 2008 Feb; 4(2):68-9. Epub 2007 Oct 30.
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44. Krieg JR Jr, Veldhuis JD, Thornhill BA, Chevalier RL, Gil G. Disruption of growth hormone secretion, male-pattern gene expression, and sexually dimorphic body growth in young rats with chronic renal failure. Endocrine 2008; in press, on line.
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45. Roelfsema F, Kok S, Kok P, Pereira AM, Biermasz NR, Smit JW, Frolich M, Keenan DM, Veldhuis JD, Romijn JA. Pituitary-horone secretion by thyrotropinomas. Pituitary 2008; in press.
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46. Chattopadhyay S, Keenan DM, Veldhuis JD. Probabilistic recovery of neuroendocrine pulsatile, secretory and kinetic structure: an alternating discrete and continuous scheme. Q. Appl. Math 2008; 66(3):401-21.
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47. Keenan DM, Alexander S, Irvine CH, Veldhuis JD. Quantifying nonlinear interactions within the hypothalamo-pituitary-adrenal axis in the conscious horse. Endocrinology 2008; in press, on line.
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48. Veldhuis JD, Keenan DM, Bailey JN, Adeniji A, Miles JM, Paulo R, Cosma M, Soares-Welch C. Testosterone supplementation in older men restrains insulin-like growth factor's dose-dependent feedback inhibition of pulsatile GH secretion. J Clin Endocrinol Metab 2008; in press, on line.
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49. Veldhuis JD, Keenan DM, Pincus SM. Motiviations and methods for analyzing pulsatile hormone secretion. Endocr Rev 2008; in press, on line.
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50. Weltman A, Weltman JY, Winfield DW, Frick K, Patrie J, Kok P, Gaesser A, Veldhuis JD. Effects of continuous vs intermittent exercise, obesity and gender on GH secretion. J Clin Endocrinol Metab 2008; in press, on line.
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51. Aksglaede L, Jensen RB, Carlsen E, Kok P, Keenan DM, Veldhuis JD. Increased basal and pulsatile secretion of follicle stimulating hormone and luteinizing hormone in young men with 47,XXY or 46,XX karyotypes. Eur J Endocrinol 2008; 158(6):803-10.
    View PubMed
52. Liu PY, Keenan DM, Kok P, Padmanabhan V, O'Byrne KT, Veldhuis JD. Sensitivity and specificity of pulse detection using a new deconvolution method. Neuroendocrinol 2008; 63(5):536-41.
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53. Liu PY, Iranmanesh A, Keenan DM, Pincus SM, Veldhuis JD. A noninvasive measure of negative-feedback strength, approximate entropy, unmasks strong diurnal variations in the regularity of LH secretion. Am J Physiol Endocrinol Metab 2007 Nov; 293(5):E1409-15. Epub 2007 Sep 11.
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54. Veldhuis JD, Keenan DM, Bowers CY. Peripheral estrogen receptor-alpha selectively modulates the waveform of GH secretory bursts in healthy women. Am J Physiol Regul Integr Comp Physiol 2007 Oct; 293(4):R1514-21.
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55. Muniyappa R, Sorkin JD, Veldhuis JD, Harman SM, Munzer T, Bhasin S, Blackman MR. Long-term testosterone supplementation augments overnight growth hormone secretion in healthy older men. Am J Physiol Endocrinol Metab 2007 Sep; 293(3):E769-75. Epub 2007 Jun 05.
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56. Takahashi PY, Votruba P, Abu-Rub M, Mielke K, Veldhuis JD. Age attenuates testosterone secretion driven by amplitude-varying pulses of recombinant human luteinizing hormone during acute gonadotrope inhibition in healthy men. J Clin Endocrinol Metab 2007 Sep; 92(9):3626-32. Epub 2007 Jun 19.
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57. Iranmanesh A, Carpenter PC, Mielke K, Bowers CY, Veldhuis JD. Putative somatostatin suppression potentiates adrenocorticotropin secretion driven by ghrelin and human corticotropin-releasing hormone. J Clin Endocrinol Metab 2007 Sep; 92(9):3653-9 Epub 2007 Jun 12.
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58. Veldhuis JD, Keenan DM, Bowers CY. Estimation of the size and shape of GH secretory bursts in healthy women using a physiological estradiol clamp and variable-waveform deconvolution model. Am J Physiol Regul Integr Comp Physiol 2007 Sep; 293(3):R1013-21 Epub 2007 May 30.
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59. Veldhuis JD, Cosma M, Erickson D, Paulo R, Mielke K, Farhy LS, Bowers CY. Tripartite control of growth hormone secretion in women during controlled estradiol repletion. J Clin Endocrinol Metab 2007 Jun; 92(6):2336-45. Epub 2007 Apr 03.
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60. van der Klaauw AA, Pereira AM, van Thiel SW, Frolich M, Iranmanesh A, Veldhuis JD, Roelfsema F, Romijn JA. Attenuated pulse size, disorderly growth hormone and prolactin secretion with preserved nyctohemeral rhythm distinguish irradiated from surgically treated acromegaly patients. Clin Endocrinol (Oxf) 2007 Apr; 66(4):489-98.
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61. Jensen RB, Vielwerth S, Larsen T, Greisen G, Veldhuis J, Juul A. Pituitary-gonadal function in adolescent males born appropriate or small for gestational age with or without intrauterine growth restriction. J Clin Endocrinol Metab 2007 Apr; 92(4):1353-7.
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62. Farhy LS, Bowers CY, Veldhuis JD. Model-projected mechanistic bases for sex differences in growth hormone regulation in humans. Am J Physiol Regul Integr Comp Physiol 2007 Apr; 292(4):R1577-93.
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63. Ritzel RA, Meier JJ, Lin CY, Veldhuis JD, Butler PC. Human islet amyloid polypeptide oligomers disrupt cell coupling, induce apoptosis, and impair insulin secretion in isolated human islets. Diabetes 2007 Jan; 56(1):65-71.
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64. Carroll BJ, Cassidy F, Naftolowitz D, Tatham NE, Wilson WH, Iranmanesh A, Liu PY, Veldhuis JD. Pathophysiology of hypercortisolism in depression. Acta Psychiatr Scand 2007; 115(Suppl 433):90-103.
65. Escobar ME, Ropelato MG, Ballerini MG, Gryngarten MG, Rudaz MC, Veldhuis JD, Barontini M. Acceleration of luteinizing hormone pulse frequency in adolescent girls with a history of central precocious puberty with versus without hyperandrogenism. Horm Res 2007; 68(6):278-85. Epub 2007 Jun 20.
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66. Iranmanesh A, Carpenter PC, Mielke K, Bowers CY, Veldhuis JD. Putative somatostatin withdrawal potentiates adrenocorticotropin secretion driven by ghrelin and human corticotropin-releasing hormone. J Clin Endocrinol Metab 2007; 92(9):3653-9.
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67. Liu PY, Takahashi PY, Roebuck PD, Veldhuis JD. Age or factors associated with aging attenuate testosterone's concentration-dependent enhancement of the regularity of luteinizing hormone secretion in healthy men. J Clin Endocrinol Metab 2006 Oct; 91(10):4077-84. Epub 2006 Jul 25.
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68. Veldhuis JD, Keenan DM, Iranmanesh A, Mielke K, Miles JM, Bowers CY. Estradiol potentiates ghrelin-stimulated pulsatile growth hormone secretion in postmenopausal women. J Clin Endocrinol Metab 2006 Sep; 91(9):3559-65. Epub 2006 Jun 27.
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69. Meneilly GS, Veldhuis JD, Elahi D. Pulsatile insulin secretion in elderly patients with diabetes. Diabetes Res Clin Pract 2006 Aug; 73(2):218-20. Epub 2006 Apr 18.
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70. Meier JJ, Hong-McAtee I, Galasso R, Veldhuis JD, Moran A, Hering BJ, Butler PC. Intrahepatic transplanted islets in humans secrete insulin in a coordinate pulsatile manner directly into the liver. Diabetes 2006 Aug; 55(8):2324-32.
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71. Matveyenko AV, Veldhuis JD, Butler PC. Mechanisms of impaired fasting glucose and glucose intolerance induced by an approximate 50% pancreatectomy. Diabetes 2006 Aug; 55(8):2347-56.
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72. Glintborg D, Hermann AP, Andersen M, Hagen C, Beck-Nielsen H, Veldhuis JD, Henriksen JE. Effect of pioglitazone on glucose metabolism and luteinizing hormone secretion in women with polycystic ovary syndrome. Fertil Steril 2006 Aug; 86(2):385-97. Epub 2006 Jun 16.
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73. Franco C, Veldhuis JD, Iranmanesh A, Brandberg J, Lonn L, Andersson B, Bengtsson BA, Svensson J, Johannsson G. Thigh intermuscular fat is inversely associated with spontaneous GH release in post-menopausal women with abdominal obesity. Eur J Endocrinol 2006 Aug; 155(2):261-8.
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74. Svensson J, Johannsson G, Iranmanesh A, Albertsson-Wikland K, Veldhuis JD, Bengtsson BA. GH secretory pattern in young adults who discontinued GH treatment for GH deficiency and decreased longitudinal growth in childhood. Eur J Endocrinol 2006 Jul; 155(1):91-9.
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75. Keenan DM, Takahashi PY, Liu PY, Roebuck PD, Nehra AX, Iranmanesh A, Veldhuis JD. An ensemble model of the male gonadal axis: illustrative application in aging men. Endocrinology 2006 Jun; 147(6):2817-28. Epub 2006 Mar 02.
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76. Ulloa-Aguirre A, Portocarrero L, Zarinan T, Olivares A, Carranza-Lira S, Veldhuis JD, Lopez-Alvarenga JC. Effects of metformin on inappropriate LH release in women with polycystic ovarian syndrome and insulin resistance. Reprod Biomed Online 2006 Jun; 12(6):669-83.
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77. Mazziotti G, Cimino V, De Menis E, Bonadonna S, Bugari G, De Marinis L, Veldhuis JD, Giustina A. Active acromegaly enhances spontaneous parathyroid hormone pulsatility. Metabolism 2006 Jun; 55(6):736-40.
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78. Veldhuis JD, Iranmanesh A, Mielke K, Miles JM, Carpenter PC, Bowers CY. Ghrelin potentiates growth hormone secretion driven by putative somatostatin withdrawal and resists inhibition by human corticotropin-releasing hormone. J Clin Endocrinol Metab 2006 Jun; 91(6):2441-6.
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79. van der Klaauw AA, Pereira AM, van Thiel SW, Smit JW, Corssmit EP, Biermasz NR, Frolich M, Iranmanesh A, Veldhuis JD, Roelfsema F, Romijn JA. GH deficiency in patients irradiated for acromegaly: significance of GH stimulatory tests in relation to the 24 h GH secretion. Eur J Endocrinol 2006 Jun; 154(6):851-8.
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80. Veldhuis JD, Iranmanesh A, Mielke K, Miles JM, Carpenter PC, Bowers CY. Ghrelin potentiates growth hormone secretion driven by putative somatostatin withdrawal and resists inhibition by human corticotropin-releasing hormone. J Clin Endocrinol Metab 2006 Jun; 91(6):2441-6. Epub 2006 Mar 14.
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81. Weltman A, Weltman JY, Roy CP, Wideman L, Patrie J, Evans WS, Veldhuis JD. Growth hormone response to graded exercise intensities is attenuated and the gender difference abolished in older adults. J Appl Physiol 2006 May; 100(5):1623-9. Epub 2005 Dec 29.
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82. Young EA, Veldhuis JD. Disordered adrenocorticotropin secretion in women with major depression. J Clin Endocrinol Metab 2006 May; 91(5):1924-8. Epub 2006 Feb 14.
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83. Meier JJ, Kjems LL, Veldhuis JD, Lefebvre P, Butler PC. Postprandial suppression of glucagon secretion depends on intact pulsatile insulin secretion: further evidence for the intraislet insulin hypothesis. Diabetes 2006 Apr; 55(4):1051-6.
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84. Ritzel RA, Veldhuis JD, Butler PC. The mass, but not the frequency, of insulin secretory bursts in isolated human islets is entrained by oscillatory glucose exposure. Am J Physiol Endocrinol Metab 2006 Apr; 290(4):E750-6. Epub 2005 Nov 08.
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85. Veldhuis JD, Roemmich JN, Richmond EJ, Bowers CY. Somatotropic and gonadotropic axes linkages in infancy, childhood, and the puberty-adult transition. Endocr Rev 2006 Apr; 27(2):101-40. Epub 2006 Jan 24.
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86. McComb JJR, Qian XP, Veldhuis JD, McGlone JJ, Norman RL. Neuroendocrine responses to psychological stress in eumenorrheic and oligomenorrheic women. Stress: The International Journal on the Biology of Stress 2006 Mar; 9(1):41-51.
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87. Ritzel RA, Butler AE, Rizza RA, Veldhuis JD, Butler PC. Relationship between beta-cell mass and fasting blood glucose concentration in humans. Diabetes Care 2006 Mar; 29(3):717-8.
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88. McComb JJ, Qian XP, Veldhuis JD, J McGlone J, Norman RL. Neuroendocrine responses to psychological stress in eumenorrheic and oligomenorrheic women. Stress 2006 Mar; 9(1):41-51.
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89. Natesampillai S, Zapico ME, Urrutia R, Veldhuis JD. A novel functional interaction between the Sp1-like protein KLF13 and SREBP-Sp1 activation complex underlies regulation of low density lipoprotein receptor promoter function. J Biol Chem 2006 Feb 10; 281(6):3040-7.
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90. Natesampillai S, Fernandez-Zapico ME, Urrutia R, Veldhuis JD. A novel functional interaction between the Sp1-like protein KLF13 and SREBP-Sp1 activation complex underlies regulation of low density lipoprotein receptor promoter function. J Biol Chem 2006 Feb 10; 281(6):3040-7. Epub 2005 Nov 22.
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91. Liu PY, Pincus SM, Takahashi PY, Roebuck PD, Iranmanesh A, Keenan DM, Veldhuis JD. Aging attenuates both the regularity and joint synchrony of LH and testosterone secretion in normal men: analyses via a model of graded GnRH receptor blockade. Am J Physiol Endocrinol Metab 2006 Jan; 290(1):E34-E41.
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92. Weltman A, Veldhuis JD. Single and combined effects of growth hormone and testosterone in healthy older men. Horm Res 2006; 66(Suppl 1):49-57.
93. Veldhuis JD. Current concepts of estrogen-regulated growth hormone in postmenopausal women. Current Medical Literature - GH and Growth Factors 2006; 1(1):7-15.
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94. Svensson J, Johannsson G, Iranmanesh A, Albersson-Wikland K, Veldhuis JD, Bengtsson B. Growth hormone secretory pattern in young adults who discontinued GH treatment for GH deficiency and decreased longitudinal growth in childhood. Eur J Endocrinol 2006; 155(1):91-9.
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95. Weltman A, Weltman JY, Pritzlaff-Roy CJ, Wideman L, Patrie J, Evans WS, Veldhuis JD. The growth hormone response to graded exercise intensities is attenuated and the gender difference abolished in older adults. J Appl Physiol 2006; 100:1623-9.
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96. Chattopadhyay S, Veldhuis JD, Keenan DM. Probabilistic recovery of pulsatile secretory and kinetic structure: an alternating discrete and continuous schema. Quarterly of Appl Math 2006; 55(8):2324-32.
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97. van der Klaauw AA, Pereira AM, van Thiel SW, Smit JWA, Corssmit EPM, Biermasz NR, Frolich M, Iranmanesh A, Veldhuis JD, Roelfsema F, Romijn JA. Growth hormone deficiency in patients irradiated for acromegaly: significance of stimulatory tests in relation to the twenty-four hour GH secretion. Eur J Endocrinol 2006; 154(6):851-8.
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98. Iranmanesh A, Veldhuis JD. Utility of ultrasensitive growth hormone assays in assessing aging-related hyposomatotropism. Endocrinol Metab Clin North Am 2005 Dec; 34(4):853-64.
99. Veldhuis JD, Erickson D, Iranmanesh A, Miles JM, Bowers CY. Sex-steroid control of the aging somatotropic axis. Endocrinology & Metabolism Clinics of North America 2005 Dec; 34(4):877-93.
100. Liu PY, Iranmanesh A, Nehra AX, Keenan DM, Veldhuis JD. Mechanisms of hypoandrogenemia in healthy aging men. Endocrinology & Metabolism Clinics of North America 2005 Dec; 34(4):935-55.
101. Veldhuis JD, Keenan DM, Roelfsema F, Iranmanesh A. Aging-related adaptations in the corticotropic axis: Modulation by gender. Endocrinology & Metabolism Clinics of North America 2005 Dec; 34(4):993-1014.
102. Veldhuis JD, Erickson D, Mielke K, Farhy LS, Keenan DM, Bowers CY. Distinctive inhibitory mechanisms of age and relative visceral adiposity on growth hormone secretion in pre- and postmenopausal women studied under a hypogonadal clamp. J Clin Endocrinol Metab 2005 Nov; 90(11):6006-13. Epub 2005 Aug 09.
     View PubMed
103. Meneilly GS, Veldhuis JD, Elahi D. Deconvolution analysis of rapid insulin pulses before and after six weeks of continuous subcutaneous administration of glucagon-like peptide-1 in elderly patients with type 2 diabetes. J Clin Endocrinol Metab 2005 Nov; 90(11):6251-6.
     View PubMed
104. Veldhuis JD, Patrie JM, Frick K, Weltman JY, Weltman AL. Administration of recombinant human GHRH-1,44-amide for 3 months reduces abdominal visceral fat mass and increases physical performance measures in postmenopausal women. European Journal of Endocrinology 2005 Nov; 153(5):669-77.
     View PubMed
105. Keenan DM, Chattopadhyay S, Veldhuis JD. Composite model of time-varying appearance and disappearance of neurohormone pulse signals in blood. J Theor Biol 2005 Oct 7; 236(3):242-55.
     View PubMed
106. Liu PY, Takahashi PY, Roebuck PD, Iranmanesh A, Veldhuis JD. Aging in healthy men impairs recombinant human luteinizing hormone (LH)-stimulated testosterone secretion monitored under a two-day intravenous pulsatile LH clamp. J Clin Endocrinol Metab 2005 Oct; 90(10):5544-50.
     View PubMed
107. Roemmich JN, Clark PA, Weltman A, Veldhuis JD, Rogol AD. Pubertal alterations in growth and body composition: IX. Altered spontaneous secretion and metabolic clearance of growth hormone in overweight youth. Metabolism: Clinical & Experimental 2005 Oct; 54(10):1374-83.
     View PubMed
108. Glintborg D, Stoving RK, Hagen C, Hermann AP, Frystyk J, Veldhuis JD, Flyvbjerg A, Andersen M. Pioglitazone treatment increases spontaneous growth hormone (GH) secretion and stimulated GH levels in polycystic ovary syndrome. J Clin Endocrinol Metab 2005 Oct; 90(10):5605-12.
     View PubMed
109. Hollingdal M, Sturis J, Gall MA, Damsbo P, Pincus S, Veldhuis JD, Porksen N, Schmitz O, Juhl CB. Repaglinide treatment amplifies first-phase insulin secretion and high-frequency pulsatile insulin release in Type 2 diabetes. Diabetic Medicine 2005 Oct; 22(10):1408-13.
     View PubMed
110. Veldhuis JD, Keenan DM, Mielke K, Miles JM, Bowers CY. Testosterone supplementation in healthy older men drives GH and IGF-I secretion without potentiating peptidyl secretagogue efficacy. European Journal of Endocrinology 2005 Oct; 153(4):577-86.
     View PubMed
111. Liu PY, Takahashi PY, Roebuck PD, Iranmanesh A, Veldhuis JD. Age-specific changes in the regulation of LH-dependent testosterone secretion: assessing responsiveness to varying endogenous gonadotropin output in normal men. Am J Physiol Regul Integr Comp Physiol 2005 Sep; 289(3):R721-8.
112. Iranmanesh A, Veldhuis JD. Combined inhibition of types I and II 5 alpha-reductase selectively augments the basal (nonpulsatile) mode of testosterone secretion in young men. J Clin Endocrinol Metab 2005 Jul; 90(7):4232-7.
     View PubMed
113. Veldhuis JD, Iranmanesh A, Bowers CY. Joint mechanisms of impaired growth-hormone pulse renewal in aging men. J Clin Endocrinol Metab 2005 Jul; 90(7):4177-83.
     View PubMed
114. Soares-Welch C, Mielke KL, Bowers CY, Veldhuis JD. Short-term testosterone supplementation does not activate GH and IGF-I production in postmenopausal women. Clinical Endocrinology 2005 Jul; 63(1):32-8.
     View PubMed
115. Liu PY, Pincus SM, Keenan DM, Roelfsema F, Veldhuis JD. Joint synchrony of reciprocal hormonal signaling in human paradigms of both ACTH excess and cortisol depletion. Am J Physiol Endocrinol Metab 2005 Jul; 289(1):E160-5.
     View PubMed
116. Farhy LS, Veldhuis JD. Deterministic construct of amplifying actions of ghrelin on pulsatile growth hormone secretion. Am J Physiol Regul Integr Comp Physiol 2005 Jun; 288(6):R1649-63.
117. Meier JJ, Veldhuis JD, Butler PC. Pulsatile insulin secretion dictates systemic insulin delivery by regulating hepatic insulin extraction in humans. Diabetes 2005 Jun; 54(6):1649-56.
     View PubMed
118. Veldhuis JD, Frystyk J, Iranmanesh A, Orskov H. Testosterone and estradiol regulate free insulin-like growth factor I (IGF-I), IGF binding protein 1 (IGFBP-1), and dimeric IGF-I/IGFBP-1 concentrations. J Clin Endocrinol Metab 2005 May; 90(5):2941-7.
     View PubMed
119. Veldhuis JD, Farhy L, Weltman AL, Kuipers J, Weltman J, Wideman L. Gender modulates sequential suppression and recovery of pulsatile growth hormone secretion by physiological feedback signals in young adults. J Clin Endocrinol Metab 2005 May; 90(5):2874-81. Epub 2005 Feb 22.
     View PubMed
120. Takahashi PY, Liu PY, Roebuck PD, Iranmanesh A, Veldhuis JD. Graded inhibition of pulsatile luteinizing hormone secretion by a selective gonadotropin-releasing hormone (GnRH)-receptor antagonist in healthy men: evidence that age attenuates hypothalamic GnRH outflow. J Clin Endocrinol Metab 2005 May; 90(5):2768-74.
     View PubMed
121. Veldhuis JD, Veldhuis NJD, Keenan DM, Iranmanesh A. Age diminishes the testicular steroidogenic response to repeated intravenous pulses of recombinant human LH during acute GnRH-receptor blockade in healthy men. Am J Physiol Endocrinol Metab 2005 Apr; 288(4):E775-81.
     View PubMed
122. Liu PY, Hoey KA, Mielke KL, Veldhuis JD, Khosla S. A randomized placebo-controlled trial of short-term graded transdermal estradiol in healthy gonadotropin-releasing hormone agonist-suppressed pre- and postmenopausal women: Effects on serum markers of bone turnover, insulin-like growth factor-I, and osteoclastogenic mediators. J Clin Endocrinol Metab 2005 Apr; 90(4):1953-60.
     View PubMed
123. Soares-Welch C, Farhy L, Mielke KL, Mahmud FH, Miles JM, Bowers CY, Veldhuis JD. Complementary secretagogue pairs unmask prominent gender-related contrasts in mechanisms of growth hormone pulse renewal in young adults. J Clin Endocrinol Metab 2005 Apr; 90(4):2225-32. Epub 2005 Jan 05.
     View PubMed
124. van Aken MO, Pereira AM, van Thiel SW, van den Berg G, Frolich M, Veldhuis JD, Romijn JA, Roelfsema F. Irregular and frequent cortisol secretory episodes with preserved diurnal rhythmicity in primary adrenal Cushing's syndrome. J Clin Endocrinol Metab 2005 Mar; 90(3):1570-7.
     View PubMed
125. Veldhuis JD, Anderson SM, Iranmanesh A, Bowers CY. Testosterone blunts feedback inhibition of growth hormone secretion by experimentally elevated insulin-like growth factor-I concentrations. J Clin Endocrinol Metab 2005 Mar; 90(3):1613-7.
     View PubMed
126. Veldhuis JD, Bae A, Swerdloff RS, Iranmanesh A, Wang C. Experimentally induced androgen depletion accentuates ethnicity-related contrasts in luteinizing hormone secretion in Asian and Caucasian men. J Clin Endocrinol Metab 2005 Mar; 90(3):1632-8.
     View PubMed
127. Erickson D, Keenan DM, Farhy L, Mielke K, Bowers CY, Veldhuis JD. Determinants of dual secretagogue drive of burst-like growth hormone secretion in premenopausal women studied under a selective estradiol clamp. J Clin Endocrinol Metab 2005 Mar; 90(3):1741-51. Epub 2004 Dec 21.
     View PubMed
128. Liu PY, Pincus SM, Keenan DM, Roelfsema F, Veldhuis JD. Analysis of bidirectional pattern synchrony of concentration-secretion pairs: implementation in the human testicular and adrenal axes. Am J Physiol Regul Integr Comp Physiol 2005 Feb; 288(2):R440-6.
129. Veldhuis JD, Roemmich JN, Richmond EJ, Rogol AD, Lovejoy JC, Sheffield-Moore M, Mauras N, Bowers CY. Endocrine control of body composition in infancy, childhood, and puberty. Endocr Rev 2005 Feb; 26(1):114-46.
     View PubMed
130. Bonadonna S, Burattin A, Nuzzo M, Bugari G, Rosei EA, Valle D, Iori N, Bilezikian JP, Veldhuis JD, Giustina A. Chronic glucocorticoid treatment alters spontaneous pulsatile parathyroid hormone secretory dynamics in human subjects. European Journal of Endocrinology 2005 Feb; 152(2):199-205.
     View PubMed
131. van Aken MO, Pereira AM, Frolich M, Romijn JA, Pijl H, Veldhuis JD, Roelfsema F. Growth hormone secretion in primary adrenal Cushing's syndrome is disorderly and inversely correlated with body mass index. American Journal of Physiology - Endocrinology & Metabolism 2005 Jan; 288(1):E63-E70.
     View PubMed
132. Veldhuis JD, Iranmanesh A. Short-term aromatase-enzyme blockade unmasks impaired feedback adaptations in luteinizing hormone and testosterone secretion in older men. J Clin Endocrinol Metab 2005 Jan; 90(1):211-8. Epub 2004 Oct 13.
     View PubMed
133. Veldhuis JD, Iranmanesh A, Mulligan T. Age and testosterone feedback jointly control the dose-dependent actions of gonadotropin-releasing hormone in healthy men. J Clin Endocrinol Metab 2005 Jan; 90(1):302-9.
     View PubMed
134. Veldhuis JD, Keenan DM, Iranmanesh A. Mechanisms of ensemble failure of the male gonadal axis in aging. J Endocrinol Invest 2005; 28(3 Suppl):8-13.
     View PubMed
135. Seals RC, Urban RJ, Sekar N, Veldhuis JD. Up-regulation of basal transcriptional activity of the cytochrome P450 cholesterol side-chain cleavage (CYP11A) gene by isoform-specific calcium-calmodulin-dependent protein kinase in primary cultures of ovarian granulosa cells. Endocrinology 2004 Dec; 145(12):5616-22.
     View PubMed
136. Veldhuis JD, Patrie JT, Brill KT, Weltman JY, Mueller EE, Bowers CY, Weltman A. Contributions of gender and systemic estradiol and testosterone concentrations to maximal secretagogue drive of burst-like growth hormone secretion in healthy middle-aged and older adults. J Clin Endocrinol Metab 2004 Dec; 89(12):6291-6.
     View PubMed
137. Veldhuis JD, Patrie JT, Frick K, Weltman JY, Weltman A. Sustained growth hormone (GH) and insulin-like growth factor I responses to prolonged high-dose twice-daily GH-releasing hormone stimulation in middle-aged and older men. J Clin Endocrinol Metab 2004 Dec; 89(12):6325-30.
     View PubMed
138. Seals RC, Urban RJ, Sekar N, Veldhuis JD. Up-regulation of basal transcriptional activity of the cytochrome P450 cholesterol side-chain cleavage (CYP11A) gene by isoform-specific calcium-calmodulin-dependent protein kinase in primary cultures of ovarian granulosa cells. Endocrinology 2004 Dec; 145(12):5616-22 Epub 2004 Aug 19.
     View PubMed
139. Veldhuis JD, Weltman JY, Weltman AL, Iranmanesh A, Muller EE, Bowers CY. Age and secretagogue type jointly determine dynamic growth hormone responses to exogenous insulin-like growth factor-negative feedback in healthy men. J Clin Endocrinol Metab 2004 Nov; 89(11):5542-8.
     View PubMed
140. Veldhuis JD, Iranmanesh A, Keenan DM. Erosion of endogenous testosterone-driven negative feedback on pulsatile luteinizing hormone secretion in healthy aging men. J Clin Endocrinol Metab 2004 Nov; 89(11):5753-61.
     View PubMed
141. Keenan DM, Roelfsema F, Veldhuis JD. Endogenous ACTH concentration-dependent drive of pulsatile cortisol secretion in the human. American Journal of Physiology - Endocrinology & Metabolism 2004 Oct; 287(4):E652-61.
     View PubMed
142. Liu PY, Swerdloff RS, Veldhuis JD. The rationale, efficacy and safety of androgen therapy in older men: Future research and current practice recommendations. J Clin Endocrinol Metab 2004 Oct; 89(10):4789-96.
     View PubMed
143. Posener JA, DeBattista C, Veldhuis JD, Province MA, Williams GH, Schatzberg AF. Process irregularity of cortisol and adrenocorticotropin secretion in men with major depressive disorder. Psychoneuroendocrinology 2004 Oct; 29(9):1129-37.
     View PubMed
144. Irving BA, Patrie JT, Anderson SM, Watson-Winfield DD, Frick KI, Evans WS, Veldhuis JD, Weltman A. The effects of time following acute growth hormone administration on metabolic and power output measures during acute exercise. J Clin Endocrinol Metab 2004 Sep; 89(9):4298-305.
     View PubMed
145. Veldhuis JD, Iranmanesh A. Pulsatile intravenous infusion of recombinant human luteinizing hormone under acute gonadotropin-releasing hormone receptor blockade reconstitutes testosterone secretion in young men. J Clin Endocrinol Metab 2004 Sep; 89(9):4474-9.
     View PubMed
146. Iranmanesh A, Bowers CY, Veldhuis JD. Activation of somatostatin-receptor subtype-2/-5 suppresses the mass, frequency, and irregularity of growth hormone (GH)-releasing peptide-2-stimulated GH secretion in men. J Clin Endocrinol Metab 2004 Sep; 89(9):4581-7.
     View PubMed
147. Erickson D, Keenan DM, Mielke K, Bradford K, Bowers CY, Miles JM, Veldhuis JD. Dual secretagogue drive of burst-like growth hormone secretion in postmenopausal compared with premenopausal women studied under an experimental estradiol clamp. J Clin Endocrinol Metab 2004 Sep; 89(9):4746-54.
     View PubMed
148. Sekar N, Veldhuis JD. Involvement of Sp1 and SREBP-1a in transcriptional activation of the LDL receptor gene by insulin and LH in cultured porcine granulosa-luteal cells. American Journal of Physiology - Endocrinology & Metabolism 2004 Jul; 287(1):E128-35.
     View PubMed
149. Farhy LS, Veldhuis JD. Putative GH pulse renewal: periventricular somatostatinergic control of an arcuate-nuclear somatostatin and GH-releasing hormone oscillator. Am J Physiol Regul Integr Comp Physiol 2004 Jun; 286(6):R1030-42.
150. Zhang GQ, Veldhuis JD. Insulin drives transcriptional activity of the CYP17 gene in primary cultures of swine theca cells. Biol Reprod 2004 Jun; 70(6):1600-5.
     View PubMed
151. Zhang GQ, Veldhuis JD. Requirement for proximal putative Sp1 and AP-2 cis-deoxyribonucleic acid elements in mediating basal and luteinizing hormone- and insulin-dependent in vitro transcriptional activation of the CYP17 gene in porcine theca cells. Endocrinology 2004 Jun; 145(6):2760-6.
     View PubMed
152. van Aken MO, Pereira AM, van den Berg G, Romijn JA, Veldhuis JD, Roelfsema F. Profound amplification of secretory-burst mass and anomalous regularity of ACTH secretory process in patients with Nelson's syndrome compared with Cushing's disease. Clin Endocrinol (Oxf) 2004 Jun; 60(6):765-72.
     View PubMed
153. Bowers CY, Granda R, Mohan S, Kuipers J, Baylink D, Veldhuis JD. Sustained elevation of pulsatile growth hormone (GH) secretion and insulin-like growth factor I (IGF-I), IGF-binding protein-3 (IGFBP-3), and IGFBP-5 concentrations during 30-day continuous subcutaneous infusion of GH-releasing peptide-2 in older men and women. J Clin Endocrinol Metab 2004 May; 89(5):2290-300.
     View PubMed
154. Keenan DM, Alexander S, Irvine CHG, Clarke I, Scott C, Turner A, Tilbrook AJ, Canny BJ, Veldhuis JD. Reconstruction of in vivo time-evolving neuroendocrine dose-response properties unveils admixed deterministic and stochastic elements. Proc Natl Acad Sci U S A 2004 Apr 27; 101(17):6740-5.
     View PubMed
155. van Dam EWCM, Roelfsema F, Veldhuis JD, Hogendoorn S, Westenberg J, Helmerhorst FM, Frolich M, Krans HMJ, Meinders AE, Pijl H. Retention of estradiol negative feedback relationship to LH predicts ovulation in response to caloric restriction and weight loss in obese patients with polycystic ovary syndrome. Am J Physiol Endocrinol Metab 2004 Apr; 286(4):E615-20.
     View PubMed
156. Licinio J, Caglayan S, Ozata M, Yildiz BO, de Miranda PB, O'Kirwan F, Whitby R, Liang LY, Cohen P, Bhasin S, Krauss RM, Veldhuis JD, Wagner AJ, DePaoli AM, McCann SM, Wong ML. Phenotypic effects of leptin replacement on morbid obesity, diabetes mellitus, hypogonadism, and behavior in leptin-deficient adults. Proc Natl Acad Sci U S A 2004 Mar 30; 101(13):4531-6.
     View PubMed
157. Veldhuis JD, Evans WS, Iranmanesh A, Weltman AL, Bowers CY. Short-term testosterone supplementation relieves growth hormone autonegative feedback in men. J Clin Endocrinol Metab 2004 Mar; 89(3):1285-90.
     View PubMed
158. Veldhuis JD, Anderson SM, Kok P, Iranmanesh A, Frystyk J, Orskov H, Keenan DM. Estradiol supplementation modulates growth hormone (GH) secretory-burst waveform and recombinant human insulin-like growth factor-I-enforced suppression of endogenously driven GH release in postmenopausal women. J Clin Endocrinol Metab 2004 Mar; 89(3):1312-8.
     View PubMed
159. Keenan DM, Veldhuis JD. Divergent gonadotropin-gonadal dose-responsive coupling in healthy young and aging men. Am J Physiol Regul Integr Comp Physiol 2004 Feb 1; 286(2):R381-9.
160. Ritzel RA, Hansen JB, Veldhuis JD, Butler PC. Induction of beta-cell rest by a Kir6.2/SUR1-selective K-ATP-channel opener preserves beta-cell insulin stores and insulin secretion in human islets cultured at high (11 mM) glucose. J Clin Endocrinol Metab 2004 Feb 1; 89(2):795-805.
     View PubMed
161. Veldhuis JD, Patrie J, Wideman L, Patterson M, Weltman JY, Weltman A. Contrasting negative-feedback control of endogenously driven and exercise-stimulated pulsatile growth hormone secretion in women and men. J Clin Endocrinol Metab 2004 Feb 1; 89(2):840-6.
     View PubMed
162. Biermasz NR, Pereira AM, Frolich M, Romijn JA, Veldhuis JD, Roelfsema F. Octreotide represses secretory-burst mass and nonpulsatile secretion but does not restore event frequency or orderly GH secretion in acromegaly. Am J Physiol Endocrinol Metab 2004 Jan 1; 286(1):E25-E30.
     View PubMed
163. Weekers F, Michalaki M, Coopmans W, Van Herck E, Veldhuis JD, Darras VM, Van den Berghe G. Endocrine and metabolic effects of growth hormone (GH) compared with GH-releasing peptide, thyrotropin-releasing hormone, and insulin infusion in a rabbit model of prolonged critical illness. Endocrinology 2004 Jan; 145(1):205-13.
     View PubMed
164. Veldhuis JD, Anderson SM, Patrie JT, Bowers CY. Estradiol supplementation in postmenopausal women doubles rebound-like release of growth hormone (GH) triggered by sequential infusion and withdrawal of somatostatin: evidence that estrogen facilitates endogenous GH-releasing hormone drive. J Clin Endocrinol Metab 2004 Jan; 89(1):121-7.
     View PubMed
165. Ostergard T, Degn KB, Gall MA, Carr RD, Veldhuis JD, Thomsen MK, Rizza RA, Schmitz O. The insulin secretagogues glibenclamide and repaglinide do not influence growth hormone secretion in humans but stimulate glucagon secretion during profound insulin deficiency. J Clin Endocrinol Metab 2004 Jan; 89(1):297-302.
     View PubMed
166. Seals RC, Urban RJ, Garmey JC, Veldhuis JD. Upregulation of basal transcriptional activity of the cytochrome P450 cholesterol side-chain cleavage (CYP11A) gene by isoform-specific calcium calmodulin-dependent protein kinase in primary cultures of ovarian granulosa cells Endocrinology 2004; 145:5616-22.
     View PubMed
167. Schmitt CP, Obry J, Feneberg R, Veldhuis JD, Mehls O, Ritz E, Schaefer F. beta 1-adrenergic blockade augments pulsatile PTH secretion in humans. J Am Soc Nephrol 2003 Dec; 14(12):3245-50.
     View PubMed
168. Keenan DM, Evans WS, Veldhuis JD. Control of LH secretory-burst frequency and interpulse-interval regularity in women. American Journal of Physiology - Endocrinology & Metabolism 2003 Nov 1; 285(5):E938-48.
     View PubMed
169. Veldhuis JD, Evans WS, Bowers CY. Estradiol supplementation enhances submaximal feed-forward drive of growth hormone (GH) secretion by recombinant human GH-releasing hormone-1,44-amide in a putatively somatostatin-withdrawn milieu. J Clin Endocrinol Metab 2003 Nov 1; 88(11):5484-9.
     View PubMed
170. Keenan DM, Veldhuis JD. Cortisol feedback state governs adrenocorticotropin secretory-burst shape, frequency, and mass in a dual-waveform construct: time of day-dependent regulation. Am J Physiol Regul Integr Comp Physiol 2003 Nov; 285(5):R950-61. Epub 2003 Jul 03.
     View PubMed
171. Farhy LS, Veldhuis JD. Joint pituitary-hypothalamic and intrahypothalamic autofeedback construct of pulsatile growth hormone secretion. Am J Physiol Regul Integr Comp Physiol 2003 Nov; 285(5):R1240-9. Epub 2003 Jul 17.
     View PubMed
172. Veldhuis JD, Bowers CY. Sex-steroid modulation of growth hormone (GH) secretory control: three-peptide ensemble regulation under dual feedback restraint by GH and IGF-I. Endocrine 2003 Oct; 22(1):25-40.
     View PubMed
173. Veldhuis JD, Bowers CY. Human GH pulsatility: An ensemble property regulated by age and gender. J Endocrinol Invest 2003 Sep; 26(9):799-813.
     View PubMed
174. Weltman A, Wideman L, Weltman JY, Veldhuis JD. Neuroendocrine control of GH release during acute aerobic exercise. J Endocrinol Invest 2003 Sep; 26(9):843-50.
     View PubMed
175. Keenan DM, Roelfsema F, Biermasz N, Veldhuis JD. Physiological control of pituitary hormone secretory-burst mass, frequency, and waveform: a statistical formulation and analysis. Am J Physiol Regul Integr Comp Physiol 2003 Sep; 285(3):R664-73. Epub 2003 May 08.
     View PubMed
176. Song SH, Rhodes CJ, Veldhuis JD, Butler PC. Diazoxide attenuates glucose-induced defects in first-phase insulin release and pulsatile insulin secretion in human islets. Endocrinology 2003 Aug; 144(8):3399-405.
     View PubMed
177. Feneberg R, Schaefer F, Veldhuis JD. Neuroendocrine adaptations in renal disease. Pediatr Nephrol 2003 Jun; 18(6):492-7.
     View PubMed
178. Smith RF, French NP, Saphier PW, Lowry PJ, Veldhuis JD, Dobson H. Identification of stimulatory and inhibitory inputs to the hypothalamic-pituitary-adrenal axis during hypoglycaemia or transport in ewes. J Neuroendocrinol 2003 Jun; 15(6):572-85.
     View PubMed
179. Veldhuis JD. Neuroendocrine facets of human puberty. Neurobiol Aging 2003 May-Jun; 24(Suppl 1):S93-S119.
     View PubMed
180. Chan JL, Heist K, DePaoli AM, Veldhuis JD, Mantzoros CS. The role of falling leptin levels in the neuroendocrine and metabolic adaptation to short-term starvation in healthy men. J Clin Invest 2003 May; 111(9):1409-21.
     View PubMed
181. Veldhuis JD, Bowers CY. Three-peptide control of pulsatile and entropic feedback-sensitive modes of growth hormone secretion: Modulation by estrogen and aromatizable androgen. J Pediatr Endocrinol Metab 2003 May; 16(Suppl 3):587-605.
     View PubMed
182. Schmitt CP, Locken S, Mehls O, Veldhuis JD, Lehnert T, Ritz E, Schaefer F. PTH pulsatility but not calcium sensitivity is restored after total parathyroidectomy with heterotopic autotransplantation. J Am Soc Nephrol 2003 Feb; 14(2):407-14.
     View PubMed
183. Ritzel RA, Veldhuis JD, Butler PC. Glucose stimulates pulsatile insulin secretion from human pancreatic islets by increasing secretory burst mass: Dose-response relationships. J Clin Endocrinol Metab 2003 Feb; 88(2):742-7.
     View PubMed
184. Veldhuis JD. A tripeptidyl ensemble perspective of interactive control of growth hormone secretion. Horm Res 2003; 60(Suppl 1):86-101.
     View PubMed
185. Ritzel RA, Hansen JB, Veldhuis JD, Butler PC. Induction of beta-cell rest by a kir6.2/SUR1-selective KATP-channel opener preserves beta-cell insulin stores and insulin secretion in human islets cultured at high (11 mM) glucose. J Clin Endocrinol Metab 2003; 89(2):795-805.
     View PubMed
186. Schmitt CP, Locken S, Mehls O, Veldhuis JD, Lehnert T, Ritz E, Schaefer F. Parathyroid-hormone pulsatility but not calcium sensitivity is restored after total parathyroidectomy with heterotopic autotransplantation. J Am Soc Nephrol 2003; 14(2):407-14.
     View PubMed
187. Rogol AD, Blethen SL, Sy JP, Veldhuis JD. Do growth hormone (GH) serial sampling, insulin-like growth factor-I (IGF-I) or auxologic measurements have an advantage over GH stimulation testing in predicting the linear growth response to GH therapy? Clinical Endocrinology 2003; 58:229-23.
     View PubMed
188. Veldhuis JD, Pincus SM, Keenan DM. Noninvasive in vivo investigative probes of adaptive mechanisms of neuroendocrine regulation: the paradigm of the hypothalamo-pituitary-gonadal axis in the aging male. J Endocrinol Invest 2003; 26(7 Suppl):2-14.
     View PubMed
189. Schmitt, CP, Obry J, Feneberg R, Veldhuis JD, Mehis O, Ritz E, Schaefer F. FBeta 1-adrenergic blockade augments pulsatile parathormone secretion in humans J Am Soc Nephrol 2003; 14(12):3245-50.
     View PubMed
190. Veldhuis JD, Bowers CY. Human growth-hormone pulsatility: an ensemble property regulated by age and gender. J Clin Endocrinol Metab 2003; 26(9):799-813.
     View PubMed
191. Veldhuis JD, Bidlingmaier M, Anderson SM, Evans WS, Wu Z, Strasburger CJ. Impact of experimental blockade of peripheral growth hormone (GH) receptors on the kinetics of endogenous and exogenous GH removal in healthy women and men. J Clin Endocrinol Metab 2002 Dec; 87(12):5737-45.
     View PubMed
192. Rall LC, Walsmith JM, Snydman L, Reichlin S, Veldhuis JD, Kehayias JJ, Abad LW, Lundgren NT, Roubenoff R. Cachexia in rheumatoid arthritis is not explained by decreased growth hormone secretion. Arthritis Rheum 2002 Oct; 46(10):2574-7.
     View PubMed
193. Leung KC, Howe C, Gui LY, Trout G, Veldhuis JD, Ho KK. Physiological and pharmacological regulation of 20-kDa growth hormone. American Journal of Physiology - Endocrinology & Metabolism 2002 Oct; 283(4):E836-43.
     View PubMed
194. Van Dam EW, Roelfsema F, Helmerhorst FH, Frolich M, Meinders AE, Veldhuis JD, Pijl H. Low amplitude and disorderly spontaneous growth hormone release in obese women with or without polycystic ovary syndrome. J Clin Endocrinol Metab 2002 Sep; 87(9):4225-30.
     View PubMed
195. Richmond E, Rogol AD, Basdemir D, Veldhuis OL, Clarke W, Bowers CY, Veldhuis JD. Accelerated escape from GH autonegative feedback in midpuberty in males: Evidence for time-delimited GH-induced somatostatinergic outflow in adolescent boys. J Clin Endocrinol Metab 2002 Aug; 87(8):3837-44.
     View PubMed
196. Garcia-Rudaz MC, Ropelato MG, Escobar ME, Veldhuis JD, Barontini M. Amplified and orderly growth hormone secretion characterizes lean adolescents with polycystic ovary syndrome. European Journal of Endocrinology 2002 Aug; 147(2):207-16.
     View PubMed
197. Moulas AN, Krieg RJ Jr, Veldhuis JD, Chan JC. Effect of the GH secretagogue L-163,255 and restricted feeding time on GH pulsatility in the rat. European Journal of Endocrinology 2002 Jul; 147(1):143-8.
     View PubMed
198. Young IR, Chan EC, Smith R, Chrousos GP, Veldhuis JD, Canny BJ. Effect of antalarmin, a novel corticotropin-releasing hormone antagonist, on the dynamic function of the preterm ovine fetal hypothalamo-pituitary-adrenal axis. Neuroendocrinology 2002 Jul; 76(1):47-54.
     View PubMed
199. Svensson J, Veldhuis JD, Iranmanesh A, Bengtsson BA, Johannsson G. Increased orderliness of growth hormone (GH) secretion in GH-deficient adults with low serum insulin-like growth factor I. J Clin Endocrinol Metab 2002 Jun; 87(6):2863-9.
     View PubMed
200. Quigg M, Kiely JM, Shneker B, Veldhuis JD, Bertram EH III. Interictal and postictal alterations of pulsatile secretions of luteinizing hormone in temporal lobe epilepsy in men. Ann Neurol 2002 May; 51(5):559-66.
     View PubMed
201. Van den Berghe G, Baxter RC, Weekers F, Wouters P, Bowers CY, Iranmanesh A, Veldhuis JD, Bouillon R. The combined administration of GH-releasing peptide-2 (GHRP-2), TRH and GnRH to men with prolonged critical illness evokes superior endocrine and metabolic effects compared to treatment with GHRP-2 alone. Clin Endocrinol (Oxf) 2002 May; 56(5):655-69.
     View PubMed
202. Feneberg R, Sparber M, Veldhuis JD, Mehls O, Ritz E, Schaefer F. Altered temporal organization of plasma insulin oscillations in chronic renal failure. J Clin Endocrinol Metab 2002 May; 87(5):1965-73.
     View PubMed
203. Pritzlaff-Roy CJ, Widemen L, Weltman JY, Abbott R, Gutgesell M, Hartman ML, Veldhuis JD, Weltman A. Gender governs the relationship between exercise intensity and growth hormone release in young adults. J Appl Physiol 2002 May; 92(5):2053-60.
     View PubMed
204. Van Dam EW, Roelfsema F, Veldhuis JD, Helmerhorst FM, Frolich M, Meinders AE, Krans HM, Pijl H. Increase in daily LH secretion in response to short-term calorie restriction in obese women with PCOS. American Journal of Physiology - Endocrinology & Metabolism 2002 Apr; 282(4):E865-72.
     View PubMed
205. Farhy LS, Straume M, Johnson ML, Kovatchev B, Veldhuis JD. Unequal autonegative feedback by GH models the sexual dimorphism in GH secretory dynamics. Am J Physiol Regul Integr Comp Physiol 2002 Mar; 282(3):R753-64.
     View PubMed
206. Veldhuis JD, Zhang G, Garmey JC. Troglitazone, an insulin-sensitizing thiazolidinedione, represses combined stimulation by LH and insulin of de novo androgen biosynthesis by thecal cells in vitro. J Clin Endocrinol Metab 2002 Mar; 87(3):1129-33.
     View PubMed
207. Weekers F, Van Herck E, Coopmans W, Michalaki M, Bowers CY, Veldhuis JD, Van den Berghe G. A novel in vivo rabbit model of hypercatabolic critical illness reveals a biphasic neuroendocrine stress response. Endocrinology 2002 Mar; 143(3):764-74.
     View PubMed
208. Maccario M, Veldhuis JD, Broglio F, Vito LD, Arvat E, Deghenghi R, Ghigo E. Impact of two or three daily subcutaneous injections of hexarelin, a synthetic growth hormone (GH) secretagogue, on 24-h GH, prolactin, adrenocorticotropin and cortisol secretion in humans. European Journal of Endocrinology 2002 Mar; 146(3):310-8.
     View PubMed
209. Porksen N, Grofte T, Greisen J, Mengel A, Juhl C, Veldhuis JD, Schmitz O, Rossle M, Vilstrup H. Human insulin release processes measured by intraportal sampling. American Journal of Physiology - Endocrinology & Metabolism 2002 Mar; 282(3):E695-702.
     View PubMed
210. Veldhuis JD, Fletcher TP, Gatford KL, Egan AR, Clarke IJ. Hypophyseal-portal somatostatin (SRIH) and jugular venous growth hormone secretion in the conscious unrestrained ewe. Neuroendocrinology 2002 Feb; 75(2):83-91.
     View PubMed
211. Lado-Abeal J, Veldhuis JD, Norman RL. Glucose relays information regarding nutritional status to the neural circuits that control the somatotropic, corticotropic, and gonadotropic axes in adult male rhesus macaques. Endocrinology 2002 Feb; 143(2):403-10.
     View PubMed
212. Juhl CB, Hollingdal M, Sturis J, Jakobsen G, Agerso H, Veldhuis J, Porksen N, Schmitz O. Bedtime administration of NN2211, a long-acting GLP-1 derivative, substantially reduces fasting and postprandial glycemia in type 2 diabetes. Diabetes 2002 Feb; 51(2):424-9.
     View PubMed
213. Veldhuis JD, Evans WS, Bowers CY. Impact of estradiol supplementation on dual peptidyl drive of GH secretion in postmenopausal women. J Clin Endocrinol Metab 2002 Feb; 87(2):859-66.
     View PubMed
214. Gentili A, Mulligan T, Godschalk M, Clore J, Patrie J, Iranmanesh A, Veldhuis JD. Unequal impact of short-term testosterone repletion on the somatotropic axis of young and older men. J Clin Endocrinol Metab 2002 Feb; 87(2):825-34.
     View PubMed
215. Song SH, Kjems L, Ritzel R, McIntyre SM, Johnson ML, Veldhuis JD, Butler PC. Pulsatile insulin secretion by human pancreatic islets. J Clin Endocrinol Metab 2002 Jan; 87(1):213-21.
     View PubMed
216. Schoppee PD, Garmey JC, Veldhuis JD. Putative activation of the peroxisome proliferator-activated receptor gamma impairs androgen and enhances progesterone biosynthesis in primary cultures of porcine theca cells. Biol Reprod 2002 Jan; 66(1):190-8.
     View PubMed
217. Roelfsema F, Biermasz NR, Veldhuis JD. Pulsatile, nyctohemeral and entropic characteristics of GH secretion in adult GH-deficient patients: selectively decreased pulsatile release and increased secretory disorderliness with preservation of diurnal timing and gender distinctions. Clin Endocrinol (Oxf) 2002 Jan; 56(1):79-87.
     View PubMed
218. Clarke I, Moore L, Veldhuis J. Intensive direct cavernous sinus sampling identifies high-frequency, nearly random patterns of FSH secretion in ovariectomized ewes: combined appraisal by RIA and bioassay. Endocrinology 2002 Jan; 143(1):117-29.
     View PubMed
219. Hollingdal M, Juhl CB, Dall R, Sturis J, Veldhuis JD, Schmitz O, Porksen N. Glucocorticoid induced insulin resistance impairs basal but not glucose entrained high-frequency insulin pulsatility in humans. Diabetologia 2002 Jan; 45(1):49-55.
     View PubMed
220. Wright N, Papadea N, Veldhuis JD, Pandey JP, Bell NH. Growth hormone secretion and bone mineral density in prepubertal black and white boys. Calcif Tissue Int 2002; 70(3):146-15.
     View PubMed
221. Moulas AN, Krieg Jr RJ, Veldhuis JD, Chan JCM. Effect of the growth hormone (GH) secretagogue L-163,255 and restricted feeding time on GH pulsatility in the rat. Europ J Endocrinol 2002; 147(1):143-14.
222. Porksen N, Hollingdal M, Juhl C, Butler P, Veldhuis JD, Schmitz O. Pulsatile insulin secretion: detection, regulation and role in diabetes. Diabetes 2002; 51:S245-254.
     View PubMed
223. Juhl C, Grofte T, Butler PC, Veldhuis JD, Schmitz O, Porksen N. Effects of fasting on physiologically pulsatile insulin release in healthy humans. Diabetes 2002; 51:S245-S254.
224. Lovejoy JC, Smith SR, Champagne C, Most MM, Lefevre M, DeLany JP, Denkins YM, Rood JC, Veldhuis JD, Bray GA. Effects of diets enriched in saturated (palmitic), monounsaturated (oleic), or trans (elaidic) on insulin sensitivity and substrate oxidation in healthy adults. Diabetes Care 2002; 25:1283-128.
     View PubMed
225. Krieg Jr RJ, Chan W, Lin KC, Kuemmerle NB, Veldhuis JD, Chan JCM. Growth hormone (GH) secretagogue treatment uremic rats: GH secretion and growth-related mRNA expression. Pediatr Nephrol 2002; 17(8):585-90.
     View PubMed
226. Brill KT, Weltman AL, Gentili A, Patrie JT, Fryburg DA, Hanks JB, Urban RJ, Veldhuis JD. Single and combined effects of growth hormone and testosterone administration on measures of body composition, physical performance, mood, sexual function, bone turnover, and muscle gene expression in healthy older men. J Clin Endocrinol Metab 2002; 87(12):5649-57.
     View PubMed
227. López-Alvarenga JC, Zariñán T, Olivares A, González-Barranco J, Veldhuis JD, Ulloa-Aguirre A. Poorly controlled type I diabetes mellitus in young men selectively suppresses luteinizing hormone secretory burst mass. J Clin Endocrinol Metab 2002; 87(12):5507-15.
     View PubMed
228. Salvatori R, Fan X, Veldhuis JD, Couch R. Serum GH response to pharmacological stimuli and physical exercise in two siblings with two new inactivatingmutations in the GH-releasing hormone receptor gene. Europ J Endo 2002; 147(5):591-6.
229. Earnhardt RC, Veldhuis JD, Cornett G, Hanks JB. Pathophysiology of hyperinsulinemia following pancreas transplantaton: altered pulsatile versus basal insulin secretion and the role of specific transplant anatomy in dogs. Annals of Surgery 2002; 236(4):480-90.
     View PubMed
230. Veldhuis JD, Johnson ML, Veldhuis OL, Straume M, Pincus SM. Impact of pulsatility on the ensemble orderliness (approximate entropy) of neurohormone secretion. Am J Physiol Regul Integr Comp Physiol 2001 Dec; 281(6):R1975-85.
231. Malmlof K, Bauer MK, Johansen PB, Ankersen M, Veldhuis JD. Daily low-dose administration of growth hormone secretagogue stimulates pulsatile growth hormone secretion and elevates plasma insulin-like growth factor-1 levels in pigs. Endocr J 2001 Dec; 16(3):195-9.
     View PubMed
232. Keenan DM, Veldhuis JD. Disruption of the hypothalamic luteinizing hormone pulsing mechanism in aging men. Am J Physiol Regul Integr Comp Physiol 2001 Dec; 281(6):R1917-24.
     View PubMed
233. Gill MS, Tillmann V, Veldhuis JD, Clayton PE. Patterns of GH output and their synchrony with short-term height increments influence stature and growth performance in normal children. J Clin Endocrinol Metab 2001 Dec; 86(12):5860-3.
     View PubMed
234. Anderson SM, Wideman L, Patrie JT, Weltman A, Bowers CY, Veldhuis JD. E2 supplementation selectively relieves GH's autonegative feedback on GH-releasing peptide-2-stimulated GH secretion. J Clin Endocrinol Metab 2001 Dec; 86(12):5904-11.
     View PubMed
235. Veldhuis JD, Iranmanesh A, Naftolowitz D, Tatham N, Cassidy F, Carroll BJ. Corticotropin secretory dynamics in humans under low glucocorticoid feedback. J Clin Endocrinol Metab 2001 Nov; 86(11):5554-63.
     View PubMed
236. Mulligan T, Iranmanesh A, Veldhuis JD. Pulsatile iv infusion of recombinant human LH in leuprolide-suppressed men unmasks impoverished Leydig-cell secretory responsiveness to midphysiological LH drive in the aging male. J Clin Endocrinol Metab 2001 Nov; 86(11):5547-53.
     View PubMed
237. Barontini M, Garcia-Rudaz MC, Veldhuis JD. Mechanisms of hypothalamic-pituitary-gonadal disruption in polycystic ovarian syndrome. Arch Med Res 2001 Nov-Dec; 32(6):544-52.
     View PubMed
238. Pijl H, Langendonk JG, Burggraaf J, Frolich M, Cohen AF, Veldhuis JD, Meinders AE. Altered neuroregulation of GH secretion in viscerally obese premenopausal women. J Clin Endocrinol Metab 2001 Nov; 86(11):5509-15.
     View PubMed
239. Kjems LL, Kirby BM, Welsh EM, Veldhuis JD, Straume M, McIntyre SS, Yang D, Lefebvre P, Butler PC. Decrease in beta-cell mass leads to impaired pulsatile insulin secretion, reduced postprandial hepatic insulin clearance, and relative hyperglucagonemia in the minipig. Diabetes 2001 Sep; 50(9):2001-12.
     View PubMed
240. Weltman A, Weltman JY, Veldhuis JD, Hartman ML. Body composition, physical exercise, growth hormone and obesity. Eating & Weight Disorders: EWD 2001 Sep; 6(3 Suppl):28-37.
     View PubMed
241. Juhl CB, Porksen N, Pincus SM, Hansen AP, Veldhuis JD, Schmitz O. Acute and short-term administration of a sulfonylurea (gliclazide) increases pulsatile insulin secretion in type 2 diabetes. Diabetes 2001 Aug; 50(8):1778-84.
     View PubMed
242. Sekar N, Veldhuis JD. Concerted transcriptional activation of the low density lipoprotein receptor gene by insulin and luteinizing hormone in cultured porcine granulosa-luteal cells: possible convergence of protein kinase a, phosphatidylinositol 3-kinase, and mitogen-activated protein kinase signaling pathways. Endocrinology 2001 Jul; 142(7):2921-8.
     View PubMed
243. Veldhuis JD, Bidlingmaier M, Anderson SM, Wu Z, Strasburger CJ. Lowering total plasma insulin-like growth factor I concentrations by way of a novel, potent, and selective growth hormone (GH) receptor antagonist, pegvisomant (B2036-peg), augments the amplitude of GH secretory bursts and elevates basal/nonpulsatile GH release in healthy women and men. J Clin Endocrinol Metab 2001 Jul; 86(7):3304-10.
     View PubMed
244. Mantzoros CS, Ozata M, Negrao AB, Suchard MA, Ziotopoulou M, Caglayan S, Elashoff RM, Cogswell RJ, Negro P, Liberty V, Wong ML, Veldhuis J, Ozdemir IC, Gold PW, Flier JS, Licinio J. Synchronicity of frequently sampled thyrotropin (TSH) and leptin concentrations in healthy adults and leptin-deficient subjects: evidence for possible partial TSH regulation by leptin in humans. J Clin Endocrinol Metab 2001 Jul; 86(7):3284-91.
     View PubMed
245. van den Berghe G, Weekers F, Baxter RC, Wouters P, Iranmanesh A, Bouillon R, Veldhuis JD. Five-day pulsatile gonadotropin-releasing hormone administration unveils combined hypothalamic-pituitary-gonadal defects underlying profound hypoandrogenism in men with prolonged critical illness. J Clin Endocrinol Metab 2001 Jul; 86(7):3217-26.
     View PubMed
246. Bray MJ, Vick TM, Shah N, Anderson SM, Rice LW, Iranmanesh A, Evans WS, Veldhuis JD. Short-term estradiol replacement in postmenopausal women selectively mutes somatostatin's dose-dependent inhibition of fasting growth hormone secretion. J Clin Endocrinol Metab 2001 Jul; 86(7):3143-9.
     View PubMed
247. Farhy LS, Straume M, Johnson ML, Kovatchev B, Veldhuis JD. A construct of interactive feedback control of the GH axis in the male. Am J Physiol Regul Integr Comp Physiol 2001 Jul; 281(1):R38-51.
     View PubMed
248. Vore SJ, Aycock ED, Veldhuis JD, Butler PC. Anesthesia rapidly suppresses insulin pulse mass but enhances the orderliness of insulin secretory process. American Journal of Physiology - Endocrinology & Metabolism 2001 Jul; 281(1):E93-9.
     View PubMed
249. Keenan DM, Veldhuis JD. Hypothesis testing of the aging male gonadal axis via a biomathematical construct. Am J Physiol Regul Integr Comp Physiol 2001 Jun; 280(6):R1755-71.
     View PubMed
250. Shanoudy H, Soliman A, Moe S, Hadian D, Veldhuis JD, Iranmanesh A, Russell DC. Early manifestations of "sick euthyroid" syndrome in patients with compensated chronic heart failure. J Card Fail 2001 Jun; 7(2):146-52.
     View PubMed
251. Bergendah M, Veldhuis JD. Is there a physiological role for gonadotrophin oligosaccharide heterogeneity in humans? III. Luteinizing hormone heterogeneity: a medical physiologist's perspective. Hum Reprod 2001 Jun; 16(6):1058-64.
     View PubMed
252. Veldhuis JD, Anderson SM, Shah N, Bray M, Vick T, Gentili A, Mulligan T, Johnson ML, Weltman A, Evans WS, Iranmanesh A. Neurophysiological regulation and target-tissue impact of the pulsatile mode of growth hormone secretion in the human. Growth Horm IGF Res 2001 Jun; 11 Suppl A:S25-37.
     View PubMed
253. Roelfsema F, Biermasz NR, Veldman RG, Veldhuis JD, Frolich M, Stokvis-Brantsma WH, Wit JM. Growth hormone (GH) secretion in patients with an inactivating defect of the GH-releasing hormone (GHRH) receptor is pulsatile: evidence for a role for non-GHRH inputs into the generation of GH pulses. J Clin Endocrinol Metab 2001 Jun; 86(6):2459-64.
     View PubMed
254. Schnorr JA, Bray MJ, Veldhuis JD. Aromatization mediates testosterone's short-term feedback restraint of 24-hour endogenously driven and acute exogenous gonadotropin-releasing hormone-stimulated luteinizing hormone and follicle-stimulating hormone secretion in young men. J Clin Endocrinol Metab 2001 Jun; 86(6):2600-6.
     View PubMed
255. Palter SF, Tavares AB, Hourvitz A, Veldhuis JD, Adashi EY. Are estrogens of import to primate/human ovarian folliculogenesis? Endocr Rev 2001 Jun; 22(3):389-424.
     View PubMed
256. Gusenoff JA, Harman SM, Veldhuis JD, Jayme JJ, St Clai C, Munzer T, Christmas C, O'Connor KG, Stevens TE, Bellantoni MF, Pabst K, Blackman MR. Cortisol and GH secretory dynamics, and their interrelationships, in healthy aged women and men. American Journal of Physiology - Endocrinology & Metabolism 2001 Apr; 280(4):E616-25.
     View PubMed
257. Keenan DM, Licinio J, Veldhuis JD. A feedback-controlled ensemble model of the stress-responsive hypothalamo-pituitary-adrenal axis. Proc Natl Acad Sci U S A 2001 Mar 27; 98(7):4028-33.
     View PubMed
258. Veldhuis JD, Straume M, Iranmanesh A, Mulligan T, Jaffe C, Barkan A, Johnson ML, Pincus S. Secretory process regularity monitors neuroendocrine feedback and feedforward signaling strength in humans. Am J Physiol Regul Integr Comp Physiol 2001 Mar; 280(3):R721-9.
259. Waters DL, Qualls CR, Dorin R, Veldhuis JD, Baumgartner RN. Increased pulsatility, process irregularity, and nocturnal trough concentrations of growth hormone in amenorrheic compared to eumenorrheic athletes. J Clin Endocrinol Metab 2001 Mar; 86(3):1013-9.
     View PubMed
260. Anderson SM, Shah N, Evans WS, Patrie JT, Bowers CY, Veldhuis JD. Short-term estradiol supplementation augments growth hormone (GH) secretory responsiveness to dose-varying GH-releasing peptide infusions in healthy postmenopausal women. J Clin Endocrinol Metab 2001 Feb; 86(2):551-60.
     View PubMed
261. Evans WS, Anderson SM, Hull LT, Azimi PP, Bowers CY, Veldhuis JD. Continuous 24-hour intravenous infusion of recombinant human growth hormone (GH)-releasing hormone-(1-44)-amide augments pulsatile, entropic, and daily rhythmic GH secretion in postmenopausal women equally in the estrogen-withdrawn and estrogen-supplemented states. J Clin Endocrinol Metab 2001 Feb; 86(2):700-12.
     View PubMed
262. Veldhuis JD, Evans WS, Bowers CY, Anderson S. Interactive regulation of postmenopausal growth hormone insulin-like growth factor axis by estrogen and growth hormone-releasing peptide-2. Endocr J 2001 Feb; 14(1):45-62.
     View PubMed
263. Veldhuis JD, Zwart A, Mulligan T, Iranmanesh A. Muting of androgen negative feedback unveils impoverished gonadotropin-releasing hormone/luteinizing hormone secretory reactivity in healthy older men. J Clin Endocrinol Metab 2001 Feb; 86(2):529-35.
     View PubMed
264. Schmitz O, Juhl CB, Hollingdal M, Veldhuis JD, Porksen N, Pincus SM. Irregular circulating insulin concentrations in type 2 diabetes mellitus: an inverse relationship between circulating free fatty acid and the disorderliness of an insulin time series in diabetic and healthy individuals. Metabolism: Clinical & Experimental 2001 Jan; 50(1):41-6.
     View PubMed
265. Veldman RG, Frolich M, Pincus SM, Veldhuis JD, Roelfsema F. Hyperleptinemia in women with Cushing's disease is driven by high-amplitude pulsatile, but orderly and eurhythmic, leptin secretion. European Journal of Endocrinology 2001 Jan; 144(1):21-7.
     View PubMed
266. Veldhuis JD, Pincus SM, Garcia-Rudaz MC, Ropelato MG, Escobar ME, Barontini M. Disruption of the joint synchrony of luteinizing hormone, testosterone, and androstenedione secretion in adolescents with polycystic ovarian syndrome. J Clin Endocrinol Metab 2001 Jan; 86(1):72-9.
     View PubMed
267. Veldhuis JD, Pincus SM, Mitamura R, Yano K, Suzuki N, Ito Y, Makita Y, Okuno A. Developmentally delimited emergence of more orderly luteinizing hormone and testosterone secretion during late prepuberty in boys. J Clin Endocrinol Metab 2001 Jan; 86(1):80-9.
     View PubMed
268. Peacey SR, Toogood AA, Veldhuis JD, Thorner MO, Shalet SM. The relationship between 24-hour growth hormone secretion and insulin-like growth factor I in patients with successfully treated acromegaly: impact of surgery or radiotherapy. J Clin Endocrinol Metab 2001 Jan; 86(1):259-66.
     View PubMed
269. Langendonk JG, Veldhuis JD, Burggraaf J, Schoemaker RC, Cohen AF, Meinders AE, Pijl H. Estimation of growth hormone secretion rate: impact of kinetic assumptions intrinsic to the analytical approach. Am J Physiol Regul Integr Comp Physiol 2001 Jan; 280(1):R225-32.
     View PubMed
270. Juhl CB, Schmitz O, Pincus SM, Holst JJ, Veldhuis JD, Porksen N. Short-term treatment with GLP-1 increase pulsatile insulin secretion in Type II diabetes with no effect on orderliness. Diabetologia 2001; 43(5):583-8.
271. Veldhuis JD, Anderson SM, Shah N, Bray M, Vick T, Gentilli A, Mulligan T, Johnson ML, Weltman A, Evans SW, Iranmanesh A. Neurophysiological regulatio nand target-tissue impact of the pulsatile mode of growth hormone secretion in the human. Growth Horm IGF Res 2001; 11:S25-37.
     View PubMed
272. Anderson SM, Wideman L, Patrie JT, Weltman A, Bowers CY, Veldhuis JD. Estradiol supplementation selectively relieves growth hormone (GH)'sautonegative feedback on GH-releasing peptide-2 (GHRP-2)-stimulated GH secretion. J Clin Endocrinol Metab 2001; 86(12):5904-11.
     View PubMed
273. Veldman RG, Frolich M, Pincus SM, Veldhuis JD, Roelfsema F. Basal, pulsatile, entropic and twenty-four-hours rhythmic features of secondary hyperprolactinemia due to functional pituitary-stalk disconnection fully mimic tumoral (primary) hyperprolactinemia. J Clin Endocrinol Metab 2001; 86(4):1562-7.
274. Hirshberg B, Veldhuis JD, Sarlis NJ. Diurnal thyrotropin secretion in short-term profound primary hypothyroidism: does it ever persist? Thyroid 2000 Dec; 10(12):1101-6.
     View PubMed
275. Veldhuis JD. Recent neuroendocrine facets of male reproductive aging. Exp Gerontol 2000 Dec; 35(9-10):1281-308.
     View PubMed
276. Song SH, McIntyre SS, Shah H, Veldhuis JD, Hayes PC, Butler PC. Direct measurement of pulsatile insulin secretion from the portal vein in human subjects. J Clin Endocrinol Metab 2000 Dec; 85(12):4491-9.
     View PubMed
277. Castro-Fernandez C, Olivares A, Soderlund D, Lopez-Alvarenga JC, Zambrano E, Veldhuis JD, Ulloa-Aguirre A, Mendez JP. A preponderance of circulating basic isoforms is associated with decreased plasma half-life and biological to immunological ratio of gonadotropin-releasing hormone-releasable luteinizing hormone in obese men. J Clin Endocrinol Metab 2000 Dec; 85(12):4603-10.
     View PubMed
278. Veldman RG, Frolich M, Pincus SM, Veldhuis JD, Roelfsema F. Apparently complete restoration of normal daily adrenocorticotropin, cortisol, growth hormone, and prolactin secretory dynamics in adults with Cushing's disease after clinically successful transsphenoidal adenomectomy. J Clin Endocrinol Metab 2000 Nov; 85(11):4039-46.
     View PubMed
279. Bergendahl M, Iranmanesh A, Pastor C, Evans WS, Veldhuis JD. Homeostatic joint amplification of pulsatile and 24-hour rhythmic cortisol secretion by fasting stress in midluteal phase women: concurrent disruption of cortisol-growth hormone, cortisol-luteinizing hormone, and cortisol-leptin synchrony. J Clin Endocrinol Metab 2000 Nov; 85(11):4028-35.
     View PubMed
280. Sekar N, Lavoie HA, Veldhuis JD. Concerted regulation of steroidogenic acute regulatory gene expression by luteinizing hormone and insulin (or insulin-like growth factor I) in primary cultures of porcine granulosa-luteal cells. Endocrinology 2000 Nov; 141(11):3983-92.
     View PubMed
281. Wideman L, Weltman JY, Patrie JT, Bowers CY, Shah N, Story S, Weltman A, Veldhuis JD. Synergy of L-arginine and growth hormone (GH)-releasing peptide-2 on GH release: influence of gender. Am J Physiol Regul Integr Comp Physiol 2000 Oct; 279(4):R1455-66.
282. Wideman L, Weltman JY, Patrie JT, Bowers CY, Shah N, Story S, Veldhuis JD, Weltman A. Synergy of L-arginine and GHRP-2 stimulation of growth hormone in men and women: modulation by exercise. Am J Physiol Regul Integr Comp Physiol 2000 Oct; 279(4):R1467-77.
283. Pritzlaff CJ, Wideman L, Blumer J, Jensen M, Abbott RD, Gaesser GA, Veldhuis JD, Weltman A. Catecholamine release, growth hormone secretion, and energy expenditure during exercise vs. recovery in men. J Appl Physiol 2000 Sep; 89(3):937-46.
     View PubMed
284. Laedtke T, Kjems L, Porksen N, Schmitz O, Veldhuis J, Kao PC, Butler PC. Overnight inhibition of insulin secretion restores pulsatility and proinsulin/insulin ratio in type 2 diabetes. American Journal of Physiology - Endocrinology & Metabolism 2000 Sep; 279(3):E520-8.
     View PubMed
285. Weltman A, Pritzlaff CJ, Wideman L, Considine RV, Fryburg DA, Gutgesell ME, Hartman ML, Veldhuis JD. Intensity of acute exercise does not affect serum leptin concentrations in young men. Med Sci Sports Exerc 2000 Sep; 32(9):1556-61.
     View PubMed
286. Krieg RJ, Tokieda K, Chan JC, Veldhuis JD. Impact of uremia on female reproductive cyclicity, ovulation, and luteinizing hormone in the rat. Kidney Int 2000 Aug; 58(2):569-74.
     View PubMed
287. Shah N, Evans WS, Bowers CY, Veldhuis JD. Oral estradiol administration modulates continuous intravenous growth hormone (GH)-releasing peptide-2-driven GH secretion in postmenopausal women. J Clin Endocrinol Metab 2000 Aug; 85(8):2649-59.
     View PubMed
288. Weltman A, Pritzlaff CJ, Wideman L, Weltman JY, Blumer JL, Abbott RD, Hartman ML, Veldhuis JD. Exercise-dependent growth hormone release is linked to markers of heightened central adrenergic outflow. J Appl Physiol 2000 Aug; 89(2):629-35.
     View PubMed
289. Zhang G, Garmey JC, Veldhuis JD. Interactive stimulation by luteinizing hormone and insulin of the steroidogenic acute regulatory (StAR) protein and 17alpha-hydroxylase/17,20-lyase (CYP17) genes in porcine theca cells. Endocrinology 2000 Aug; 141(8):2735-42.
     View PubMed
290. Hollingdal M, Juhl CB, Pincus SM, Sturis J, Veldhuis JD, Polonsky KS, Porksen N, Schmitz O. Failure of physiological plasma glucose excursions to entrain high-frequency pulsatile insulin secretion in type 2 diabetes. Diabetes 2000 Aug; 49(8):1334-40.
     View PubMed
291. Pincus SM, Veldhuis JD, Rogol AD. Longitudinal changes in growth hormone secretory process irregularity assessed transpubertally in healthy boys. American Journal of Physiology - Endocrinology & Metabolism 2000 Aug; 279(2):E417-24.
     View PubMed
292. Jayes FC, Day RN, Garmey JC, Urban RJ, Zhang G, Veldhuis JD. Calcium ions positively modulate follicle-stimulating hormone- and exogenous cyclic 3',5'-adenosine monophosphate-driven transcription of the P450(scc) gene in porcine granulosa cells. Endocrinology 2000 Jul; 141(7):2377-84.
     View PubMed
293. Veldhuis JD, Roemmich JN, Rogol AD. Gender and sexual maturation-dependent contrasts in the neuroregulation of growth hormone secretion in prepubertal and late adolescent males and females--a general clinical research center-based study. J Clin Endocrinol Metab 2000 Jul; 85(7):2385-94.
     View PubMed
294. Nyholm B, Porksen N, Juhl CB, Gravholt CH, Butler PC, Weeke J, Veldhuis JD, Pincus S, Schmitz O. Assessment of insulin secretion in relatives of patients with type 2 (non-insulin-dependent) diabetes mellitus: evidence of early beta-cell dysfunction. Metabolism: Clinical & Experimental 2000 Jul; 49(7):896-905.
     View PubMed
295. Bergendahl M, Iranmanesh A, Mulligan T, Veldhuis JD. Impact of age on cortisol secretory dynamics basally and as driven by nutrient-withdrawal stress. J Clin Endocrinol Metab 2000 Jun; 85(6):2203-14.
     View PubMed
296. Aguirre C, Jayes FC, Veldhuis JD. Luteinizing hormone (LH) drives diverse intracellular calcium second messenger signals in isolated porcine ovarian thecal cells: preferential recruitment of intracellular Ca2+ oscillatory cells by higher concentrations of LH. Endocrinology 2000 Jun; 141(6):2220-8.
     View PubMed
297. Sartorio A, Pizzocaro A, Liberati D, De Nicolao G, Veldhuis JD, Faglia G. Abnormal LH pulsatility in women with hyperprolactinaemic amenorrhoea normalizes after bromocriptine treatment: deconvolution-based assessment. Clin Endocrinol (Oxf) 2000 Jun; 52(6):703-12.
     View PubMed
298. Juhl CB, Schmitz O, Pincus S, Holst JJ, Veldhuis J, Porksen N. Short-term treatment with GLP-1 increases pulsatile insulin secretion in Type II diabetes with no effect on orderliness. Diabetologia 2000 May; 43(5):583-8.
     View PubMed
299. Juhl CB, Porksen N, Hollingdal M, Sturis J, Pincus S, Veldhuis JD, Dejgaard A, Schmitz O. Repaglinide acutely amplifies pulsatile insulin secretion by augmentation of burst mass with no effect on burst frequency. Diabetes Care 2000 May; 23(5):675-81.
     View PubMed
300. Keenan DM, Veldhuis JD. Explicating hypergonadotropism in postmenopausal women: a statistical model. Am J Physiol Regul Integr Comp Physiol 2000 May; 278(5):R1247-57.
     View PubMed
301. Painson JC, Veldhuis JD, Tannenbaum GS. Single exposure to testosterone in adulthood rapidly induces regularity in the growth hormone release process. American Journal of Physiology - Endocrinology & Metabolism 2000 May; 278(5):E933-40.
     View PubMed
302. Veldman RG, Frolich M, Pincus SM, Veldhuis JD, Roelfsema F. Growth hormone and prolactin are secreted more irregularly in patients with Cushing's disease. Clin Endocrinol (Oxf) 2000 May; 52(5):625-32.
     View PubMed
303. Veldhuis JD, Iranmanesh A, Godschalk M, Mulligan T. Older men manifest multifold synchrony disruption of reproductive neurohormone outflow. J Clin Endocrinol Metab 2000 Apr; 85(4):1477-86.
     View PubMed
304. Lado-Abeal J, Hickox JR, Cheung TL, Veldhuis JD, Hardy DM, Norman RL. Neuroendocrine consequences of fasting in adult male macaques: effects of recombinant rhesus macaque leptin infusion. Neuroendocrinology 2000 Mar; 71(3):196-208.
     View PubMed
305. Juhl CB, Porksen N, Sturis J, Hansen AP, Veldhuis JD, Pincus S, Fineman M, Schmitz O. High-frequency oscillations in circulating amylin concentrations in healthy humans. American Journal of Physiology - Endocrinology & Metabolism 2000 Mar; 278(3):E484-90.
     View PubMed
306. Buyse J, Decuypere E, Darras VM, Vleurick LM, Kuhn ER, Veldhuis JD. Food deprivation and feeding of broiler chickens is associated with rapid and interdependent changes in the somatotrophic and thyrotrophic axes. Br Poult Sci 2000 Mar; 41(1):107-16.
     View PubMed
307. Garmey JC, Schnorr JA, Bruns ME, Bruns DE, Seaner RM, Ferguson II JE, Luking Jayes FC, Aguirre C, Veldhuis JD. Expression of parathyroid hormone-related peptide (PTH-rp) and its receptorin the porcine ovary: regulation by transforming growth factor-beta and possible paracrine effects of granulosa cell PTH-rp secretion on theca cells. Biol Reprod 2000 Feb; 62(2):334-9.
     View PubMed
308. Goodman WG, Misra S, Veldhuis JD, Portale AA, Wang HJ, Ament ME, Salusky IB. Altered diurnal regulation of blood ionized calcium and serum parathyroid hormone concentrations during parenteral nutrition. Am J Clin Nutr 2000 Feb; 71(2):560-8.
     View PubMed
309. Giustina A, Barkan A, Casanueva FF, Cavagnini F, Frohman L, Ho K, Veldhuis J, Wass J, Von Werder K, Melmed S. Criteria for cure of acromegaly: a consensus statement. J Clin Endocrinol Metab 2000 Feb; 85(2):526-9.
     View PubMed
310. Sekar N, Garmey JC, Veldhuis JD. Mechanisms underlying the steroidogenic synergy of insulin and luteinizing hormone in porcine granulosa cells: joint amplification of pivotal sterol-regulatory genes encoding the low-density lipoprotein (LDL) receptor, steroidogenic acute regulatory (stAR) protein and cytochrome P450 side-chain cleavage (P450scc) enzyme. Molecular & Cellular Endocrinology 2000 Jan 25; 159(1-2):25-35.
     View PubMed
311. Wong ML, Kling MA, Munson PJ, Listwak S, Licinio J, Prolo P, Karp B, McCutcheon IE, Geracioti TD Jr, DeBellis MD, Rice KC, Goldstein DS, Veldhuis JD, Chrousos GP, Oldfield EH, McCann SM, Gold PW. Pronounced and sustained central hypernoradrenergic function in major depression with melancholic features: relation to hypercortisolism and corticotropin-releasing hormone. Proc Natl Acad Sci U S A 2000 Jan 4; 97(1):325-30.
     View PubMed
312. Van den Berghe G, Baxter RC, Weekers F, Wouters P, Bowers CY, Veldhuis JD. A paradoxical gender dissociation within the growth hormone/insulin-like growth factor I axis during protracted critical illness. J Clin Endocrinol Metab 2000 Jan; 85(1):183-92.
     View PubMed
313. Bergendahl M, Iranmanesh A, Evans WS, Veldhuis JD. Short-term fasting selectively suppresses leptin pulse mass and 24-hour rhythmic leptin release in healthy midluteal phase women without disturbing leptin pulse frequency or its entropy control (pattern orderliness). J Clin Endocrinol Metab 2000 Jan; 85(1):207-13.
     View PubMed
314. Porksen N, Juhl C, Hollingdal M, Pincus SM, Sturis J, Veldhuis JD, Schmitz O. Concordant induction of rapid in vivo pulsatile insulin secretion by recurrent punctuated glucose infusions. American Journal of Physiology - Endocrinology & Metabolism 2000 Jan; 278(1):E162-70.
     View PubMed
315. Roelfsema R, Biermasz NR, Veldman RG, Veldhuis JD, Frolich M, Stokvis-Brantsma WH, Wit JM. Growth hormone (GH) secretion in patients with an inactivating defect of the GH-releasing hormone (GHRH) receptor is pulsatile: evidence for a role for non-GHRH inputs into the generation of GH pulses. J Clin Endocrinol Metab 2000; 86(6):2459-64.
316. Keenan DM, Sun W, Veldhuis JD. A stochastic biomathematical model of the male reproductive hormone system. SIAM J Appl Math 2000; 61(3):934-65.
317. Veldhuis JD. Nature of altered pulsatile hormone release and neuroendocrine network signaling in human aging: clinical studies of the somatotropic, gonadotropic, corticotropic, and insulin axes. Novartis Found Symp 2000; 227:163-89.
     View PubMed
318. Veldhuis JD, Giustina A. Strategies for appraising suspected growth-hormone deficiency in the adult. Endocrinologist 2000; 10:34-50.
319. Veldhuis JD. Network-like facets of neuroendocrine aging in the human: specific disruption of feedback and feedforward linkages within the aging somatotropic, gonadotropic and corticotropic axes in men and women. Journal of Anti-Aging Medicine 2000; 3(3):269-301.
320. Veldhuis JD, Johnson ML. Analysis of nonequilibrium facets of pulsatile sex-steroid secretion in presence of plasma-binding proteins. Methods Enzymol 2000; 321:239-63.
     View PubMed
321. Ropelato MG, Garcia-Rudaz MC, Castro-Fernandez C, Ulloa-Aguirre A, Escobar ME, Barontini M, Veldhuis JD. A preponderance of basic luteinizing hormone (LH) isoforms accompanies inappropriate hypersecretion of both basal and pulsatile LH in adolescents with polycystic ovarian syndrome. J Clin Endocrinol Metab 1999 Dec; 84(12):4629-36.
     View PubMed
322. Mulligan T, Jaen-Vinuales A, Godschalk M, Iranmanesh A, Veldhuis JD. Synthetic somatostatin analog (octreotide) suppresses daytime growth hormone secretion equivalently in young and older men: preserved pituitary responsiveness to somatostatin's inhibition in aging. J Am Geriatr Soc 1999 Dec; 47(12):1422-4.
     View PubMed
323. Pincus SM, Hartman ML, Roelfsema F, Thorner MO, Veldhuis JD. Hormone pulsatility discrimination via coarse and short time sampling. Am J Physiol 1999 Nov; 277(5 Pt 1):E948-57.
     View PubMed
324. Flores JA, Garmey JC, Lahav M, Veldhuis JD. Mechanisms underlying endothelin's inhibition of FSH-stimulated progesterone production by ovarian granulosa cells. Molecular & Cellular Endocrinology 1999 Oct 25; 156(1-2):169-78.
     View PubMed
325. Mackler AM, Ducsay CA, Veldhuis JD, Yellon SM. Maturation of spontaneous and agonist-induced uterine contractions in the peripartum mouse uterus. Biol Reprod 1999 Oct; 61(4):873-8.
     View PubMed
326. Veldhuis JD, Iranmanesh A, Mulligan T, Pincus SM. Disruption of the young-adult synchrony between luteinizing hormone release and oscillations in follicle-stimulating hormone, prolactin, and nocturnal penile tumescence (NPT) in healthy older men. J Clin Endocrinol Metab 1999 Oct; 84(10):3498-505.
     View PubMed
327. Veldhuis JD, Iranmanesh A, Demers LM, Mulligan T. Joint basal and pulsatile hypersecretory mechanisms drive the monotropic follicle-stimulating hormone (FSH) elevation in healthy older men: concurrent preservation of the orderliness of the FSH release process: a general clinical research center study. J Clin Endocrinol Metab 1999 Oct; 84(10):3506-14.
     View PubMed
328. Geoffriau M, Claustrat B, Veldhuis J. Estimation of frequently sampled nocturnal melatonin production in humans by deconvolution analysis: evidence for episodic or ultradian secretion. J Pineal Res 1999 Oct; 27(3):139-44.
     View PubMed
329. Bright GM, Veldhuis JD, Iranmanesh A, Baumann G, Maheshwari H, Lima J. Appraisal of growth hormone (GH) secretion: evaluation of a composite pharmacokinetic model that discriminates multiple components of GH input. J Clin Endocrinol Metab 1999 Sep; 84(9):3301-8.
     View PubMed
330. Wideman L, Weltman JY, Shah N, Story S, Veldhuis JD, Weltman A. Effects of gender on exercise-induced growth hormone release. J Appl Physiol 1999 Sep; 87(3):1154-62.
     View PubMed
331. De Nicolao G, Liberati D, Veldhuis JD, Sartorio A. LH and FSH secretory responses to GnRH in normal individuals: a non-parametric deconvolution approach. European Journal of Endocrinology 1999 Sep; 141(3):246-56.
     View PubMed
332. Mulligan T, Iranmanesh A, Kerzner R, Demers LW, Veldhuis JD. Two-week pulsatile gonadotropin releasing hormone infusion unmasks dual (hypothalamic and Leydig cell) defects in the healthy aging male gonadotropic axis. European Journal of Endocrinology 1999 Sep; 141(3):257-66.
     View PubMed
333. Lovejoy JC, Smith SR, Zachwieja JJ, Bray GA, Windhauser MM, Wickersham PJ, Veldhuis JD, Tulley R, de la Bretonne JA. Low-dose T(3) improves the bed rest model of simulated weightlessness in men and women. Am J Physiol 1999 Aug; 277(2 Pt 1):E370-9.
     View PubMed
334. Pritzlaff CJ, Wideman L, Weltman JY, Abbott RD, Gutgesell ME, Hartman ML, Veldhuis JD, Weltman A. Impact of acute exercise intensity on pulsatile growth hormone release in men. J Appl Physiol 1999 Aug; 87(2):498-504.
     View PubMed
335. Shah N, Aloi J, Evans WS, Veldhuis JD. Time mode of growth hormone (GH) entry into the bloodstream and steady-state plasma GH concentrations, rather than sex, estradiol, or menstrual cycle stage, primarily determine the GH elimination rate in healthy young women and men. J Clin Endocrinol Metab 1999 Aug; 84(8):2862-9.
     View PubMed
336. Meneilly GS, Veldhuis JD, Elahi D. Disruption of the pulsatile and entropic modes of insulin release during an unvarying glucose stimulus in elderly individuals. J Clin Endocrinol Metab 1999 Jun; 84(6):1938-43.
     View PubMed
337. Stoving RK, Veldhuis JD, Flyvbjerg A, Vinten J, Hangaard J, Koldkjaer OG, Kristiansen J, Hagen C. Jointly amplified basal and pulsatile growth hormone (GH) secretion and increased process irregularity in women with anorexia nervosa: indirect evidence for disruption of feedback regulation within the GH-insulin-like growth factor I axis. J Clin Endocrinol Metab 1999 Jun; 84(6):2056-63.
     View PubMed
338. Shah N, Evans WS, Bowers CY, Veldhuis JD. Tripartite neuroendocrine activation of the human growth hormone (GH) axis in women by continuous 24-hour GH-releasing peptide infusion: pulsatile, entropic, and nyctohemeral mechanisms. J Clin Endocrinol Metab 1999 Jun; 84(6):2140-50.
     View PubMed
339. Shah N, Evans WS, Veldhuis JD. Actions of estrogen on pulsatile, nyctohemeral, and entropic modes of growth hormone secretion. Am J Physiol 1999 May; 276(5 Pt 2):R1351-8.
     View PubMed
340. Latta K, Krieg RJ Jr, Hisano S, Veldhuis JD, Chan JC. Effect of the synthetic glucocorticoid, deflazacort, on body growth, pulsatile secretion of GH and thymolysis in the rat. European Journal of Endocrinology 1999 May; 140(5):441-6.
     View PubMed
341. Van den Berghe G, Wouters P, Weekers F, Mohan S, Baxter RC, Veldhuis JD, Bowers CY, Bouillon R. Reactivation of pituitary hormone release and metabolic improvement by infusion of growth hormone-releasing peptide and thyrotropin-releasing hormone in patients with protracted critical illness. J Clin Endocrinol Metab 1999 Apr; 84(4):1311-23.
     View PubMed
342. Groote Veldman R, van den Berg G, Pincus SM, Frolich M, Veldhuis JD, Roelfsema F. Increased episodic release and disorderliness of prolactin secretion in both micro- and macroprolactinomas. European Journal of Endocrinology 1999 Mar; 140(3):192-200.
     View PubMed
343. Bergendahl M, Evans WS, Pastor C, Patel A, Iranmanesh A, Veldhuis JD. Short-term fasting suppresses leptin and (conversely) activates disorderly growth hormone secretion in midluteal phase women--a clinical research center study. J Clin Endocrinol Metab 1999 Mar; 84(3):883-94.
     View PubMed
344. Iranmanesh A, Mulligan T, Veldhuis JD. Mechanisms subserving the physiological nocturnal relative hypoprolactinemia of healthy older men: dual decline in prolactin secretory burst mass and basal release with preservation of pulse duration, frequency, and interpulse interval--a General Clinical Research Center study. J Clin Endocrinol Metab 1999 Mar; 84(3):1083-90.
     View PubMed
345. Van den Berghe G, Wouters P, Bowers CY, de Zegher F, Bouillon R, Veldhuis JD. Growth hormone-releasing peptide-2 infusion synchronizes growth hormone, thyrotrophin and prolactin release in prolonged critical illness. European Journal of Endocrinology 1999 Jan; 140(1):17-22.
     View PubMed
346. LaVoie HA, Garmey JC, Day RN, Veldhuis JD. Concerted regulation of low density lipoprotein receptor gene expression by follicle-stimulating hormone and insulin-like growth factor I in porcine granulosa cells: promoter activation, messenger ribonucleic acid stability, and sterol feedback. Endocrinology 1999 Jan; 140(1):178-86.
     View PubMed
347. LaVoie HA, Garmey JC, Veldhuis JD. Mechanisms of insulin-like growth factor I augmentation of follicle-stimulating hormone-induced porcine steroidogenic acute regulatory protein gene promoter activity in granulosa cells. Endocrinology 1999 Jan; 140(1):146-53.
     View PubMed
348. Hoeger KM, Kolp LA, Strobl FJ, Veldhuis JD. Evaluation of LH secretory dynamics during the rat proestrous LH surge. Am J Physiol 1999 Jan; 276(1 Pt 2):R219-25.
     View PubMed
349. Feneberg R, Sparber M, Veldhuis JD, Mehls O, Ritz E, Schaefer F. Synchronous fluctuations of blood insulin and lactate concentrations in humans. J Clin Endocrinol Metab 1999 Jan; 84(1):220-7.
     View PubMed
350. Veldhuis JD. Recent insights into neuroendocrine mechanisms of aging of the human male hypothalamic-pituitary-gonadal axis. J Androl 1999 Jan-Feb; 20(1):1-17.
     View PubMed
351. Veldman RG, Frolich M, Veldhuis JD, Pincus SM, Roelfsema F. Growth hormone and prolactin are secreted more irregularly in patients with Cushing's disease. Clinical Endocrinology 1999; 52(5):625-35.
352. Giustina A, Veldhuis JD. Pathophysiology of the neuroregulation of GH secretion in experimental animals and the human. Endocrine Reviews 1999; 19:717-97.
353. Veldhuis JD. Ultradian hormone rhythms in the (human) reproductive axis. Encyclopedia of Reproduction 1999; 4:898-909.
354. Malmlof K, Bauer MK, Johansen PB, Ankersen M, Veldhuis JD. Daily low-dose GH secretagogue administration stimulates pulsatile GH secretion and elevates plasma IGF-I levels in pigs. Endocrine 16(3)195- 202 1999.
355. Keenan DM, Veldhuis JD, Yang R. Joint recovery of pulsatile and basal hormone secretion by stochastic nonlinear random-effects analysis. Am J Physiol 1998 Dec; 275(6 Pt 2):R1939-49.
     View PubMed
356. Matt DW, Gilson MP, Sales TE, Krieg RJ, Kerbeshian MC, Veldhuis JD, Evans WS. Characterization of attenuated proestrous luteinizing hormone surges in middle-aged rats by deconvolution analysis. Biol Reprod 1998 Dec; 59(6):1477-82.
     View PubMed
357. Giustina A, Veldhuis JD. Pathophysiology of the neuroregulation of growth hormone secretion in experimental animals and the human. Endocr Rev 1998 Dec; 19(6):717-97.
     View PubMed
358. Garcia-Rudaz MC, Ropelato MG, Escobar ME, Veldhuis JD, Barontini M. Augmented frequency and mass of LH discharged per burst are accompanied by marked disorderliness of LH secretion in adolescents with polycystic ovary syndrome. European Journal of Endocrinology 1998 Dec; 139(6):621-30.
     View PubMed
359. Arnold JD, Bonacruz G, Leslie GI, Veldhuis JD, Milmlow D, Silink M. Antenatal glucocorticoids modulate the amplitude of pulsatile cortisol secretion in premature neonates. Pediatr Res 1998 Dec; 44(6):876-81.
     View PubMed
360. Fliser D, Veldhuis JD, Dikow R, Schmidt-Gayk H, Ritz E. Effects of acute ACE inhibition on pulsatile renin and aldosterone secretion and their synchrony. Hypertension 1998 Nov; 32(5):929-34.
     View PubMed
361. Licinio J, Negrao AB, Mantzoros C, Kaklamani V, Wong ML, Bongiorno PB, Negro PP, Mulla A, Veldhuis JD, Cearnal L, Flier JS, Gold PW. Sex differences in circulating human leptin pulse amplitude: clinical implications. J Clin Endocrinol Metab 1998 Nov; 83(11):4140-7.
     View PubMed
362. Schmitt CP, Huber D, Mehls O, Maiwald J, Stein G, Veldhuis JD, Ritz E, Schaefer F. Altered instantaneous and calcium-modulated oscillatory PTH secretion patterns in patients with secondary hyperparathyroidism. J Am Soc Nephrol 1998 Oct; 9(10):1832-44.
     View PubMed
363. Goodman WG, Veldhuis JD, Belin TR, Van Herle AJ, Juppner H, Salusky IB. Calcium-sensing by parathyroid glands in secondary hyperparathyroidism. J Clin Endocrinol Metab 1998 Aug; 83(8):2765-72.
     View PubMed
364. Wang C, Iranmanesh A, Berman N, McDonald V, Steiner B, Ziel F, Faulkner SM, Dudley RE, Veldhuis JD, Swerdloff RS. Comparative pharmacokinetics of three doses of percutaneous dihydrotestosterone gel in healthy elderly men--a clinical research center study. J Clin Endocrinol Metab 1998 Aug; 83(8):2749-57.
     View PubMed
365. Gravholt CH, Veldhuis JD, Christiansen JS. Increased disorderliness and decreased mass and daily rate of endogenous growth hormone secretion in adult Turner syndrome: the impact of body composition, maximal oxygen uptake and treatment with sex hormones. Growth Horm IGF Res 1998 Aug; 8(4):289-98.
     View PubMed
366. Winters TA, Hanten JA, Veldhuis JD. In situ amplification of the cytochrome P-450 cholesterol side-chain cleavage enzyme mRNA in single porcine granulosa cells by IGF-1 and FSH acting alone or in concert. Endocr J 1998 Aug; 9(1):57-63.
     View PubMed
367. Flores JA, Aguirre C, Sharma OP, Veldhuis JD. Luteinizing hormone (LH) stimulates both intracellular calcium ion ([Ca2+]i) mobilization and transmembrane cation influx in single ovarian (granulosa) cells: recruitment as a cellular mechanism of LH-[Ca2+]i dose response. Endocrinology 1998 Aug; 139(8):3606-12.
     View PubMed
368. Canny BJ, Young IR, Veldhuis JD. Hypothalamo-pituitary disconnection of the late-gestation ovine fetus results in profound changes in cortisol secretion that are not reflected in commensurate changes in adrenocorticotropin secretion. Endocrinology 1998 Jul; 139(7):3210-9.
     View PubMed
369. Iranmanesh A, South S, Liem AY, Clemmons D, Thorner MO, Weltman A, Veldhuis JD. Unequal impact of age, percentage body fat, and serum testosterone concentrations on the somatotrophic, IGF-I, and IGF-binding protein responses to a three-day intravenous growth hormone-releasing hormone pulsatile infusion in men. European Journal of Endocrinology 1998 Jul; 139(1):59-71.
     View PubMed
370. Keenan DM, Veldhuis JD. A biomathematical model of time-delayed feedback in the human male hypothalamic-pituitary-Leydig cell axis. Am J Physiol 1998 Jul; 275(1 Pt 1):E157-76.
     View PubMed
371. Weltman A, Weltman JY, Kanaley JA, Rogol AD, Veldhuis JD. Repeated bouts of exercise alter the blood lactate-RPE relation. Med Sci Sports Exerc 1998 Jul; 30(7):1113-7.
     View PubMed
372. Bergendahl M, Aloi JA, Iranmanesh A, Mulligan TM, Veldhuis JD. Fasting suppresses pulsatile luteinizing hormone (LH) secretion and enhances orderliness of LH release in young but not older men. J Clin Endocrinol Metab 1998 Jun; 83(6):1967-75.
     View PubMed
373. Mauras N, Hayes V, Welch S, Rini A, Helgeson K, Dokler M, Veldhuis JD, Urban RJ. Testosterone deficiency in young men: marked alterations in whole body protein kinetics, strength, and adiposity. J Clin Endocrinol Metab 1998 Jun; 83(6):1886-92.
     View PubMed
374. Ovesen P, Vahl N, Fisker S, Veldhuis JD, Christiansen JS, Jorgensen JO. Increased pulsatile, but not basal, growth hormone secretion rates and plasma insulin-like growth factor I levels during the periovulatory interval in normal women. J Clin Endocrinol Metab 1998 May; 83(5):1662-7.
     View PubMed
375. Roubenoff R, Rall LC, Veldhuis JD, Kehayias JJ, Rosen C, Nicolson M, Lundgren N, Reichlin S. The relationship between growth hormone kinetics and sarcopenia in postmenopausal women: the role of fat mass and leptin. J Clin Endocrinol Metab 1998 May; 83(5):1502-6.
     View PubMed
376. Roemmich JN, Clark PA, Mai V, Berr SS, Weltman A, Veldhuis JD, Rogol AD. Alterations in growth and body composition during puberty: III. Influence of maturation, gender, body composition, fat distribution, aerobic fitness, and energy expenditure on nocturnal growth hormone release. J Clin Endocrinol Metab 1998 May; 83(5):1440-7.
     View PubMed
377. Roelfsema F, van den Berg G, van Dulken H, Veldhuis JD, Pincus SM. Pituitary apoplexy in acromegaly, a long-term follow-up study in two patients. J Endocrinol Invest 1998 May; 21(5):298-303.
     View PubMed
378. Veldhuis JD. Neuroendocrine control of pulsatile growth hormone release in the human: relationship with gender. Growth Horm IGF Res 1998 Apr; 8 Suppl B:49-59.
     View PubMed
379. Licinio J, Negrao AB, Mantzoros C, Kaklamani V, Wong ML, Bongiorno PB, Mulla A, Cearnal L, Veldhuis JD, Flier JS, McCann SM, Gold PW. Synchronicity of frequently sampled, 24-h concentrations of circulating leptin, luteinizing hormone, and estradiol in healthy women. Proc Natl Acad Sci U S A 1998 Mar 3; 95(5):2541-6.
     View PubMed
380. Matt DW, Kauma SW, Pincus SM, Veldhuis JD, Evans WS. Characteristics of luteinizing hormone secretion in younger versus older premenopausal women. American Journal of Obstetrics & Gynecology 1998 Mar; 178(3):504-10.
     View PubMed
381. Dewil E, Buyse J, Veldhuis JD, Mast J, De Coster R, Decuypere E. In ovo treatment with an aromatase inhibitor masculinizes postnatal hormone levels, abdominal fat pad content, and GH pulsatility in broiler chickens. Domest Anim Endocrinol 1998 Mar; 15(2):115-27.
     View PubMed
382. Wang C, Berman NG, Veldhuis JD, Der T, McDonald V, Steiner B, Swerdloff RS. Graded testosterone infusions distinguish gonadotropin negative-feedback responsiveness in Asian and white men--a Clinical Research Center study. J Clin Endocrinol Metab 1998 Mar; 83(3):870-6.
     View PubMed
383. Roelfsema F, Pincus SM, Veldhuis JD. Patients with Cushing's disease secrete adrenocorticotropin and cortisol jointly more asynchronously than healthy subjects. J Clin Endocrinol Metab 1998 Feb; 83(2):688-92.
     View PubMed
384. Van den Berghe G, de Zegher F, Baxter RC, Veldhuis JD, Wouters P, Schetz M, Verwaest C, Van der Vorst E, Lauwers P, Bouillon R, Bowers CY. Neuroendocrinology of prolonged critical illness: effects of exogenous thyrotropin-releasing hormone and its combination with growth hormone secretagogues. J Clin Endocrinol Metab 1998 Feb; 83(2):309-19.
     View PubMed
385. Gevers E, Pincus SM, Robinson IC, Veldhuis JD. Differential orderliness of the GH release process in castrate male and female rats. Am J Physiol 1998 Feb; 274(2 Pt 2):R437-44.
     View PubMed
386. van den Berg G, Pincus SM, Frolich M, Veldhuis JD, Roelfsema F. Reduced disorderliness of growth hormone release in biochemically inactive acromegaly after pituitary surgery. European Journal of Endocrinology 1998 Feb; 138(2):164-9.
     View PubMed
387. Invitti C, De Martin M, Delitala G, Veldhuis JD, Cavagnini F. Altered morning and nighttime pulsatile corticotropin and cortisol release in polycystic ovary syndrome. Metabolism: Clinical & Experimental 1998 Feb; 47(2):143-8.
     View PubMed
388. Schmitt CP, Schaefer F, Huber D, Zahn I, Veldhuis JD, Ritz E, Mehls O. 1,25(OH)2-vitamin D3 reduces spontaneous and hypocalcemia-stimulated pulsatile component of parathyroid hormone secretion. J Am Soc Nephrol 1998 Jan; 9(1):54-62.
     View PubMed
389. Porksen N, Grofte B, Nyholm B, Holst JJ, Pincus SM, Veldhuis JD, Schmitz O, Butler PC. Glucagon-like peptide 1 increases mass but not frequency or orderliness of pulsatile insulin secretion. Diabetes 1998 Jan; 47(1):45-9.
     View PubMed
390. Straume M, Johnson ML, Veldhuis JD. Statistically accurate estimation of hormone concentrations and associated uncertainties: methodology, validation, and applications. Clin Chem 1998 Jan; 44(1):116-23.
     View PubMed
391. Veldhuis JD. Pulsatile growth hormone release. In: Graham P, editor. The Cambridge encyclopedia of human growth and development. Cambridge: Cambridge University Press; 1998. p. 41.
392. Veldhuis JD. Neuroregulatory pathophysiology of impoverished growth hormone (GH) secretion in the aging human. Journal of Anti-Aging Medicine 1998; 1(3):173-96.
393. Geoffriau M, Claustrat B, Veldhuis JD. Estimation of nocturnal melatonin production in humans by deconvolution analysis. Excerpta Medica International Congress Series 1998; 1152:325-8.
394. Adinoff B, Iranmanesh A, Veldhuis JD, Fisher L. Disturbances of the stress response. The role of the HPA axis during alcohol withdrawal and abstinence. Alcohol Health & Research World 1998; 22(1):67-72.
     View PubMed
395. Meneilly GS, Ryan AS, Veldhuis JD, Elahi D. Increased disorderliness of basal insulin release, attenuated insulin secretory burst mass, and reduced ultradian rhythmicity of insulin secretion in older individuals. J Clin Endocrinol Metab 1997 Dec; 82(12):4088-93.
     View PubMed
396. Lovejoy JC, Smith SR, Bray GA, Veldhuis JD, Rood JC, Tulley R. Effects of experimentally induced mild hyperthyroidism on growth hormone and insulin secretion and sex steroid levels in healthy young men. Metabolism: Clinical & Experimental 1997 Dec; 46(12):1424-8.
     View PubMed
397. Fryburg DA, Weltman A, Jahn LA, Weltman JY, Samojlik E, Hintz RL, Veldhuis JD. Short-term modulation of the androgen milieu alters pulsatile, but not exercise- or growth hormone (GH)-releasing hormone-stimulated GH secretion in healthy men: impact of gonadal steroid and GH secretory changes on metabolic outcomes. J Clin Endocrinol Metab 1997 Nov; 82(11):3710-9.
     View PubMed
398. Kanaley JA, Weltman JY, Veldhuis JD, Rogol AD, Hartman ML, Weltman A. Human growth hormone response to repeated bouts of aerobic exercise. J Appl Physiol 1997 Nov; 83(5):1756-61.
     View PubMed
399. Korhonen J, Alfthan H, Ylostalo P, Veldhuis J, Stenman UH. Disappearance of human chorionic gonadotropin and its alpha- and beta-subunits after term pregnancy. Clin Chem 1997 Nov; 43(11):2155-63.
     View PubMed
400. Van den Berghe G, de Zegher F, Veldhuis JD, Wouters P, Gouwy S, Stockman W, Weekers F, Schetz M, Lauwers P, Bouillon R, Bowers CY. Thyrotrophin and prolactin release in prolonged critical illness: dynamics of spontaneous secretion and effects of growth hormone-secretagogues. Clin Endocrinol (Oxf) 1997 Nov; 47(5):599-612.
     View PubMed
401. Porksen N, Nyholm B, Veldhuis JD, Butler PC, Schmitz O. In humans at least 75% of insulin secretion arises from punctuated insulin secretory bursts. Am J Physiol 1997 Nov; 273(5 Pt 1):E908-14.
     View PubMed
402. Pincus SM, Veldhuis JD, Mulligan T, Iranmanesh A, Evans WS. Effects of age on the irregularity of LH and FSH serum concentrations in women and men. Am J Physiol 1997 Nov; 273(5 Pt 1):E989-95.
     View PubMed
403. Fliser D, Schaefer F, Schmid D, Veldhuis JD, Ritz E. Angiotensin II affects basal, pulsatile, and glucose-stimulated insulin secretion in humans. Hypertension 1997 Nov; 30(5):1156-61.
     View PubMed
404. Friend K, Iranmanesh A, Login IS, Veldhuis JD. Pyridostigmine treatment selectively amplifies the mass of GH secreted per burst without altering GH burst frequency, half-life, basal GH secretion or the orderliness of GH release. European Journal of Endocrinology 1997 Oct; 137(4):377-86.
     View PubMed
405. Mulligan T, Iranmanesh A, Johnson ML, Straume M, Veldhuis JD. Aging alters feed-forward and feedback linkages between LH and testosterone in healthy men. Am J Physiol 1997 Oct; 273(4 Pt 2):R1407-13.
     View PubMed
406. Veldhuis JD, Metzger DL, Martha PM Jr, Mauras N, Kerrigan JR, Keenan B, Rogol AD, Pincus SM. Estrogen and testosterone, but not a nonaromatizable androgen, direct network integration of the hypothalamo-somatotrope (growth hormone)-insulin-like growth factor I axis in the human: evidence from pubertal pathophysiology and sex-steroid hormone J Clin Endocrinol Metab 1997 Oct; 82(10):3414-20.
     View PubMed
407. Sun F, Berry DJ, Leong DA, Veldhuis JD. Recruitment of individually (all-or-none) responding cells, rather than amplitude enhancement, is the single-cell mechanism subserving the dose-responsive activation of intracellular calcium second messenger signaling by the human luteinizing-hormone receptor. Endocr J 1997 Oct; 7(2):219-26.
     View PubMed
408. Garcia E, Santos F, Rodriguez J, Martinez V, Rey C, Veldhuis J, Krieg RJ Jr. Impaired secretion of growth hormone in experimental uremia: relevance of caloric deficiency. Kidney Int 1997 Sep; 52(3):648-53.
     View PubMed
409. Foresta C, Bordon P, Rossato M, Mioni R, Veldhuis JD. Specific linkages among luteinizing hormone, follicle-stimulating hormone, and testosterone release in the peripheral blood and human spermatic vein: evidence for both positive (feed-forward) and negative (feedback) within-axis regulation. J Clin Endocrinol Metab 1997 Sep; 82(9):3040-6.
     View PubMed
410. Clark PA, Iranmanesh A, Veldhuis JD, Rogol AD. Comparison of pulsatile luteinizing hormone secretion between prepubertal children and young adults: evidence for a mass/amplitude-dependent difference without gender or day/night contrasts. J Clin Endocrinol Metab 1997 Sep; 82(9):2950-5.
     View PubMed
411. Keenan DM, Veldhuis JD. Stochastic model of admixed basal and pulsatile hormone secretion as modulated by a deterministic oscillator. Am J Physiol 1997 Sep; 273(3 Pt 2):R1182-92.
     View PubMed
412. LaVoie HA, Benoit AM, Garmey JC, Dailey RA, Wright DJ, Veldhuis JD. Coordinate developmental expression of genes regulating sterol economy and cholesterol side-chain cleavage in the porcine ovary. Biol Reprod 1997 Aug; 57(2):402-7.
     View PubMed
413. Veldhuis JD, Iranmanesh A, Weltman A. Elements in the pathophysiology of diminished growth hormone (GH) secretion in aging humans. Endocr J 1997 Aug; 7(1):41-8.
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414. Buyse J, Decuypere E, Veldhuis JD. Compensatory growth of broiler chickens is associated with an enhanced pulsatile growth hormone (GH) secretion: preferential amplification of GH secretory burst mass. Br Poult Sci 1997 Jul; 38(3):291-6.
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415. Zwart AD, Iranmanesh A, Veldhuis JD. Disparate serum free testosterone concentrations and degrees of hypothalamo-pituitary-luteinizing hormone suppression are achieved by continuous versus pulsatile intravenous androgen replacement in men: a clinical experimental model of ketoconazole-induced reversible hypoandrogenemia with controlled testosterone add-back. J Clin Endocrinol Metab 1997 Jul; 82(7):2062-9.
     View PubMed
416. Vahl N, Jorgensen JO, Skjaerbaek C, Veldhuis JD, Orskov H, Christiansen JS. Abdominal adiposity rather than age and sex predicts mass and regularity of GH secretion in healthy adults. Am J Physiol 1997 Jun; 272(6 Pt 1):E1108-16.
     View PubMed
417. Aloi JA, Bergendahl M, Iranmanesh A, Veldhuis JD. Pulsatile intravenous gonadotropin-releasing hormone administration averts fasting-induced hypogonadotropism and hypoandrogenemia in healthy, normal weight men. J Clin Endocrinol Metab 1997 May; 82(5):1543-8.
     View PubMed
418. Goodman WG, Veldhuis JD, Belin TR, Juppner H, Salusky IB. Suppressive effect of calcium on parathyroid hormone release in adynamic renal osteodystrophy and secondary hyperparathyroidism. Kidney Int 1997 May; 51(5):1590-5.
     View PubMed
419. Hartmann A, Veldhuis JD, Deuschle M, Standhardt H, Heuser I. Twenty-four hour cortisol release profiles in patients with Alzheimer's and Parkinson's disease compared to normal controls: ultradian secretory pulsatility and diurnal variation. Neurobiol Aging 1997 May-Jun; 18(3):285-9.
     View PubMed
420. Veldhuis JD, Iranmanesh A, Samojlik E, Urban RJ. Differential sex steroid negative feedback regulation of pulsatile follicle-stimulating hormone secretion in healthy older men: deconvolution analysis and steady-state sex-steroid hormone infusions in frequently sampled healthy older individuals. J Clin Endocrinol Metab 1997 Apr; 82(4):1248-54.
     View PubMed
421. Samuels MH, Veldhuis JD, Kramer P, Urban RJ, Bauer R, Mundy GR. Episodic secretion of parathyroid hormone in postmenopausal women: assessment by deconvolution analysis and approximate entropy. J Bone Miner Res 1997 Apr; 12(4):616-23.
     View PubMed
422. Giustina A, Scalvini T, Tassi C, Desenzani P, Poiesi C, Wehrenberg WB, Rogol AD, Veldhuis JD. Maturation of the regulation of growth hormone secretion in young males with hypogonadotropic hypogonadism pharmacologically exposed to progressive increments in serum testosterone. J Clin Endocrinol Metab 1997 Apr; 82(4):1210-9.
     View PubMed
423. Reyes-Fuentes A, Chavarria ME, Aguilera G, Rosado A, Iranmanesh A, Veldhuis JD. Deconvolution analysis of bioassayable LH secretion and half-life in men with idiopathic oligoasthenospermia. Int J Androl 1997 Apr; 20(2):118-25.
     View PubMed
424. van den Berg G, Pincus SM, Veldhuis JD, Frolich M, Roelfsema F. Greater disorderliness of ACTH and cortisol release accompanies pituitary-dependent Cushing's disease. European Journal of Endocrinology 1997 Apr; 136(4):394-400.
     View PubMed
425. Porksen N, Hussain MA, Bianda TL, Nyholm B, Christiansen JS, Butler PC, Veldhuis JD, Froesch ER, Schmitz O. IGF-I inhibits burst mass of pulsatile insulin secretion at supraphysiological and low IGF-I infusion rates. Am J Physiol 1997 Mar; 272(3 Pt 1):E352-8.
     View PubMed
426. Schmitz O, Porksen N, Nyholm B, Skjaerbaek C, Butler PC, Veldhuis JD, Pincus SM. Disorderly and nonstationary insulin secretion in relatives of patients with NIDDM. Am J Physiol 1997 Feb; 272(2 Pt 1):E218-26.
     View PubMed
427. Veldhuis JD, Zwart AD, Iranmanesh A. Neuroendocrine mechanisms by which selective Leydig cell castration unleashes increased pulsatile LH release. Am J Physiol 1997 Feb; 272(2 Pt 2):R464-74.
     View PubMed
428. Veldhuis JD, Norton JA, Wells SA Jr, Vinik AI, Perry RR. Surgical versus medical management of multiple endocrine neoplasia (MEN) type I. J Clin Endocrinol Metab 1997 Feb; 82(2):357-64.
     View PubMed
429. Van den Berghe G, de Zegher F, Veldhuis JD, Wouters P, Awouters M, Verbruggen W, Schetz M, Verwaest C, Lauwers P, Bouillon R, Bowers CY. The somatotropic axis in critical illness: effect of continuous growth hormone (GH)-releasing hormone and GH-releasing peptide-2 infusion. J Clin Endocrinol Metab 1997 Feb; 82(2):590-9.
     View PubMed
430. Balasubramanian K, Lavoie HA, Garmey JC, Stocco DM, Veldhuis JD. Regulation of porcine granulosa cell steroidogenic acute regulatory protein (StAR) by insulin-like growth factor I: synergism with follicle-stimulating hormone or protein kinase A agonist. Endocrinology 1997 Jan; 138(1):433-9.
     View PubMed
431. Veldhuis JD. Novel modalities for appraising individual and coordinate pulsatile hormone secretion: the paradigm of luteinizing hormone and testosterone release in the aging male. Mol Psychiatry 1997 Jan; 2(1):70-80.
     View PubMed
432. Veldhuis JD, Iranmanesh A, Urban RJ. Primary gonadal failure in men selectively amplifies the mass of follicle stimulating hormone (FSH) secreted per burst and increases the disorderliness of FSH release: reversibility with testosterone replacement. Int J Androl 1997; 20(5):297-305.
     View PubMed
433. Veldhuis JD. Altered pulsatile and coordinate secretion of pituitary hormones in aging: evidence of feedback disruption. Aging (Milano) 1997; 9(4 Suppl):19-20.
     View PubMed
434. Reutens AT, Veldhuis JD, Hoffman DM, Leung KC, Ho KY. A highly sensitive growth hormone (GH) ELISA uncovers increased contribution of a tonic mode of GH secretion in adults with organic GH deficiency. J Clin Endocrinol Metab 1997; 81:1591-7.
435. Porksen NK, Munn SR, Steers JL, Schmitz O, Veldhuis JD, Butler PC. Mechanisms of sulfonylurea's stimulation of insulin secretion in vivo: selective amplification of insulin secretory burst mass. Diabetes 1996 Dec; 45(12):1792-7.
     View PubMed
436. Veldhuis JD, Iranmanesh A. Physiological regulation of the human growth hormone (GH)-insulin-like growth factor type I (IGF-I) axis: predominant impact of age, obesity, gonadal function, and sleep. Sleep 1996 Dec; 19(10 Suppl):S221-4.
     View PubMed
437. Johnson ML, Veldhuis JD, Lampl M. Is growth saltatory? The usefulness and limitations of frequency distributions in analyzing pulsatile data. Endocrinology 1996 Dec; 137(12):5197-204.
     View PubMed
438. Schmitt CP, Schaefer F, Bruch A, Veldhuis JD, Schmidt-Gayk H, Stein G, Ritz E, Mehls O. Control of pulsatile and tonic parathyroid hormone secretion by ionized calcium. J Clin Endocrinol Metab 1996 Dec; 81(12):4236-43.
     View PubMed
439. Chapman IM, Bach MA, Van Cauter E, Farmer M, Krupa D, Taylor AM, Schilling LM, Cole KY, Skiles EH, Pezzoli SS, Hartman ML, Veldhuis JD, Gormley GJ, Thorner MO. Stimulation of the growth hormone (GH)-insulin-like growth factor I axis by daily oral administration of a GH secretogogue (MK-677) in healthy elderly subjects. J Clin Endocrinol Metab 1996 Dec; 81(12):4249-57.
     View PubMed
440. Pincus SM, Mulligan T, Iranmanesh A, Gheorghiu S, Godschalk M, Veldhuis JD. Older males secrete luteinizing hormone and testosterone more irregularly, and jointly more asynchronously, than younger males. Proc Natl Acad Sci U S A 1996 Nov 26; 93(24):14100-5.
     View PubMed
441. Bergendahl M, Evans WS, Veldhuis JD. Current concepts on ultradian rhythms of luteinizing hormone secretion in the human. Hum Reprod Update 1996 Nov-Dec; 2(6):507-18.
     View PubMed
442. Dorin RI, Ferries LM, Roberts B, Qualls CR, Veldhuis JD, Lisansky EJ. Assessment of stimulated and spontaneous adrenocorticotropin secretory dynamics identifies distinct components of cortisol feedback inhibition in healthy humans. J Clin Endocrinol Metab 1996 Nov; 81(11):3883-91.
     View PubMed
443. Martha PM Jr, Rogol AD, Veldhuis JD, Blizzard RM. A longitudinal assessment of hormonal and physical alterations during normal puberty in boys. III. The neuroendocrine growth hormone axis during late prepuberty. J Clin Endocrinol Metab 1996 Nov; 81(11):4068-74.
     View PubMed
444. Wang C, Eyre DR, Clark R, Kleinberg D, Newman C, Iranmanesh A, Veldhuis J, Dudley RE, Berman N, Davidson T, Barstow TJ, Sinow R, Alexander G, Swerdloff RS. Sublingual testosterone replacement improves muscle mass and strength, decreases bone resorption, and increases bone formation markers in hypogonadal men--a clinical research center study. J Clin Endocrinol Metab 1996 Oct; 81(10):3654-62.
     View PubMed
445. Friend K, Iranmanesh A, Veldhuis JD. The orderliness of the growth hormone (GH) release process and the mean mass of GH secreted per burst are highly conserved in individual men on successive days. J Clin Endocrinol Metab 1996 Oct; 81(10):3746-53.
     View PubMed
446. Zwart AD, Urban RJ, Odell WD, Veldhuis JD. Contrasts in the gonadotropin-releasing hormone dose-response relationships for luteinizing hormone, follicle-stimulating hormone and alpha-subunit release in young versus older men: appraisal with high-specificity immunoradiometric assay and deconvolution analysis. European Journal of Endocrinology 1996 Oct; 135(4):399-406.
     View PubMed
447. Porksen N, Munn S, Steers J, Veldhuis JD, Butler PC. Effects of glucose ingestion versus infusion on pulsatile insulin secretion. The incretin effect is achieved by amplification of insulin secretory burst mass. Diabetes 1996 Oct; 45(10):1317-23.
     View PubMed
448. Booth RA Jr, Weltman JY, Yankov VI, Murray J, Davison TS, Rogol AD, Asplin CM, Johnson ML, Veldhuis JD, Evans WS. Mode of pulsatile follicle-stimulating hormone secretion in gonadal hormone-sufficient and -deficient women--a clinical research center study. J Clin Endocrinol Metab 1996 Sep; 81(9):3208-14.
     View PubMed
449. van den Berg G, Veldhuis JD, Frolich M, Roelfsema F. An amplitude-specific divergence in the pulsatile mode of growth hormone (GH) secretion underlies the gender difference in mean GH concentrations in men and premenopausal women. J Clin Endocrinol Metab 1996 Jul; 81(7):2460-7.
     View PubMed
450. Calabresi E, Ishikawa E, Bartolini L, Delitala G, Fanciulli G, Oliva O, Veldhuis JD, Serio M. Somatostatin infusion suppresses GH secretory burst frequency and mass in normal men. Am J Physiol 1996 Jun; 270(6 Pt 1):E975-9.
     View PubMed
451. Veldhuis JD. Neuroendocrine mechanisms mediating awakening of the human gonadotropic axis in puberty. Pediatr Nephrol 1996 Jun; 10(3):304-17.
     View PubMed
452. Veldhuis JD. New modalities for understanding dynamic regulation of the somatotropic (GH) axis: explication of gender differences in GH neuroregulation in the human. J Pediatr Endocrinol Metab 1996 Jun; 9 Suppl 3:237-53.
     View PubMed
453. Porksen N, Munn SR, Steers JL, Veldhuis JD, Butler PC. Effects of somatostatin on pulsatile insulin secretion - selective inhibition of insulin burst mass. Am J Physiol Endocrinol Metab 1996 Jun; 270(6):E1043-E1049.
454. Wu FC, Butler GE, Kelnar CJ, Huhtaniemi I, Veldhuis JD. Ontogeny of pulsatile gonadotropin releasing hormone secretion from midchildhood, through puberty, to adulthood in the human male: a study using deconvolution analysis and an ultrasensitive immunofluorometric assay. J Clin Endocrinol Metab 1996 May; 81(5):1798-805.
     View PubMed
455. Reutens AT, Veldhuis JD, Hoffman DM, Leung KC, Ho KK. A highly sensitive growth hormone (GH) enzyme-linked immunosorbent assay uncovers increased contribution of a tonic mode of GH secretion in adults with organic GH deficiency. J Clin Endocrinol Metab 1996 Apr; 81(4):1591-7.
     View PubMed
456. Lahav M, Garmey JC, Veldhuis JD. Paradoxical effect of 3-isobutyl-1-methylxanthine on cytochrome P450 cholesterol side-chain cleavage mRNA accumulation in porcine granulosa cells. Molecular & Cellular Endocrinology 1996 Mar 25; 117(2):203-10.
     View PubMed
457. Wright NM, Papadea N, Willi S, Veldhuis JD, Pandey JP, Key LL, Bell NH. Demonstration of a lack of racial difference in secretion of growth hormone despite a racial difference in bone mineral density in premenopausal women--a Clinical Research Center study. J Clin Endocrinol Metab 1996 Mar; 81(3):1023-6.
     View PubMed
458. Veldhuis JD. Gender differences in secretory activity of the human somatotropic (growth hormone) axis. European Journal of Endocrinology 1996 Mar; 134(3):287-95.
     View PubMed
459. Reyes-Fuentes A, Chavarria ME, Carrera A, Aguilera G, Rosado A, Samojlik E, Iranmanesh A, Veldhuis JD. Alterations in pulsatile luteinizing hormone and follicle-stimulating hormone secretion in idiopathic oligoasthenospermic men: assessment by deconvolution analysis--a clinical research center study. J Clin Endocrinol Med 1996 Feb; 81(2):524-9.
     View PubMed
460. Bergendahl M, Vance ML, Iranmanesh A, Thorner MO, Veldhuis JD. Fasting as a metabolic stress paradigm selectively amplifies cortisol secretory burst mass and delays the time of maximal nyctohemeral cortisol concentrations in healthy men. J Clin Endocrinol Metab 1996 Feb; 81(2):692-9.
     View PubMed
461. Schaefer F, Baumann G, Haffner D, Faunt LM, Johnson ML, Mercado M, Ritz E, Mehls O, Veldhuis JD. Multifactorial control of the elimination kinetics of unbound (free) growth hormone (GH) in the human: regulation by age, adiposity, renal function, and steady state concentrations of GH in plasma. J Clin Endocrinol Metab 1996 Jan; 81(1):22-31.
     View PubMed
462. Pincus SM, Gevers EF, Robinson IC, van den Berg G, Roelfsema F, Hartman ML, Veldhuis JD. Females secrete growth hormone with more process irregularity than males in both humans and rats. Am J Physiol 1996 Jan; 270(1 Pt 1):E107-15.
     View PubMed
463. Mauras N, Rogol AD, Haymond MW, Veldhuis JD. Sex steroids, growth hormone, insulin-like growth factor-1: neuroendocrine and metabolic regulation in puberty. Horm Res 1996; 45(1-2):74-80.
     View PubMed
464. Lahav M, Garmey JC, Shupnik MA, Veldhuis JD. Dual actions of phorbol ester on cytochrome P450 cholesterol side-chain cleavage ribonucleic acid accumulation in granulosa cells. Biol Reprod 1996; 52:972-81.
465. Reyes Fuentes A, Chavarria ME, Carrera A, Aguilera G, Rosada A, Samojlik E, Iranmanesh A, Veldhuis JD. Combined alterations in pulsatile LH and FSH secretion in idiopathic oligospermic men: assessment by deconvolution analysis. J Clin Endocrinol Metab 1996; 81(2):524-9.
     View PubMed
466. Engdahl JH, Veldhuis JD, Farrell PA. Altered pulsatile insulin secretion associated with endurance training. J Appl Physiol 1995 Dec; 79(6):1977-85.
     View PubMed
467. van den Berg G, Frolich M, Veldhuis JD, Roelfsema F. Combined amplification of the pulsatile and basal modes of adrenocorticotropin and cortisol secretion in patients with Cushing's disease: evidence for decreased responsiveness of the adrenal glands. J Clin Endocrinol Metab 1995 Dec; 80(12):3750-7.
     View PubMed
468. Porksen N, Munn S, Steers J, Veldhuis JD, Butler PC. Impact of sampling technique on appraisal of pulsatile insulin secretion by deconvolution and cluster analysis. Am J Physiol 1995 Dec; 269(6 Pt 1):E1106-14.
     View PubMed
469. Veldhuis JD, Liem AY, South S, Weltman A, Weltman J, Clemmons DA, Abbott R, Mulligan T, Johnson ML, Pincus S, et al. Differential impact of age, sex steroid hormones, and obesity on basal versus pulsatile growth hormone secretion in men as assessed in an ultrasensitive chemiluminescence assay. J Clin Endocrinol Metab 1995 Nov; 80(11):3209-22.
     View PubMed
470. Maitra A, LaVoie HA, Day RN, Garmey JC, Veldhuis JD. Regulation of porcine granulosa cell 3-hydroxy-3-methylglutaryl coenzyme A reductase by insulin and insulin-like growth factor I: synergism with follicle-stimulating hormone or protein kinase A agonist. Endocrinology 1995 Nov; 136(11):5111-7.
     View PubMed
471. Flores JA, Winters TA, Knight JW, Veldhuis JD. Nature of endothelin binding in the porcine ovary. Endocrinology 1995 Nov; 136(11):5014-9.
     View PubMed
472. Mulligan T, Iranmanesh A, Gheorghiu S, Godschalk M, Veldhuis JD. Amplified nocturnal luteinizing hormone (LH) secretory burst frequency with selective attenuation of pulsatile (but not basal) testosterone secretion in healthy aged men: possible Leydig cell desensitization to endogenous LH signaling--a clinical research center study. J Clin Endocrinol Metab 1995 Oct; 80(10):3025-31.
     View PubMed
473. Samuels MH, Veldhuis J, Ridgway EC. Copulsatile release of thyrotropin and prolactin in normal and hypothyroid subjects. Thyroid 1995 Oct; 5(5):369-72.
     View PubMed
474. Cuneo RC, Hickman PE, Wallace JD, Teh BT, Ward G, Veldhuis JD, Waters MJ. Altered endogenous growth hormone secretory kinetics and diurnal GH-binding protein profiles in adults with chronic liver disease. Clin Endocrinol (Oxf) 1995 Sep; 43(3):265-75.
     View PubMed
475. Krieg RJ Jr, Latta K, Niimi K, Veldhuis JD, Chan JC. Impact of uraemia on food efficiency and the pulsatile mode of growth hormone secretion in rats. J Endocrinol 1995 Sep; 146(3):509-17.
     View PubMed
476. Lewis LL, Greenblatt EM, Rittenhouse CA, Veldhuis JD, Jaffe RB. Pulsatile release patterns of luteinizing hormone and progesterone in relation to symptom onset in women with premenstrual syndrome. Fertility & Sterility 1995 Aug; 64(2):288-92.
     View PubMed
477. Wright NM, Renault J, Willi S, Veldhuis JD, Pandey JP, Gordon L, Key LL, Bell NH. Greater secretion of growth hormone in black than in white men: possible factor in greater bone mineral density--a clinical research center study. J Clin Endocrinol Metab 1995 Aug; 80(8):2291-7.
     View PubMed
478. Benoit AM, Veldhuis JD. Differential effects of pulsatile versus continuous follicle-stimulating hormone delivery on the production of cyclic adenosine 5'-monophosphates and the accumulation of cytochrome P450 cholesterol side-chain cleavage enzyme mRNA in perifused porcine granulosa cells. Biol Reprod 1995 Jul; 53(1):46-54.
     View PubMed
479. Bergendahl M, Veldhuis JD. Altered pulsatile gonadotropin signaling in nutritional deficiency in the male. Trends Endocrinol Metab 1995 Jul; 6(5):145-59.
     View PubMed
480. Lahav M, Garmey JC, Shupnik MA, Veldhuis JD. Dual actions of phorbol ester on cytochrome P450 cholesterol side-chain cleavage messenger ribonucleic acid accumulation in porcine granulosa cells. Biol Reprod 1995 May; 52(5):972-81.
     View PubMed
481. Zambrano E, Olivares A, Mendez JP, Guerrero L, Diaz-Cueto L, Veldhuis JD, Ulloa-Aguirre A. Dynamics of basal and gonadotropin-releasing hormone-releasable serum follicle-stimulating hormone charge isoform distribution throughout the human menstrual cycle. J Clin Endocrinol Metab 1995 May; 80(5):1647-56.
     View PubMed
482. Bauer MK, Breier BH, Harding JE, Veldhuis JD, Gluckman PD. The fetal somatotropic axis during long term maternal undernutrition in sheep: evidence for nutritional regulation in utero. Endocrinology 1995 Mar; 136(3):1250-7.
     View PubMed
483. Siragy HM, Vieweg WV, Pincus S, Veldhuis JD. Increased disorderliness and amplified basal and pulsatile aldosterone secretion in patients with primary aldosteronism. J Clin Endocrinol Metab 1995 Jan; 80(1):28-33.
     View PubMed
484. Sarnyai Z, Veldhuis JD, Mello NK, Mendelson JH, Eros-Sarnyai M, Mercer G, Gelles H, Kelly M. The concordance of pulsatile ultradian release of adrenocorticotropin and cortisol in male rhesus monkeys. J Clin Endocrinol Metab 1995 Jan; 80(1):54-9.
     View PubMed
485. Tonshoff B, Veldhuis JD, Heinrich U, Mehls O. Deconvolution analysis of spontaneous nocturnal growth hormone secretion in prepubertal children with preterminal chronic renal failure and with end-stage renal disease. Pediatr Res 1995 Jan; 37(1):86-93.
     View PubMed
486. Veldhuis JD. Physiological regulation of GH secretion throughout the human lifetime. Current Medical Literature - Growth Hormone and Growth Factors 1995; 10(3):59-68.
487. Mulligan T, Johnson ML, Veldhuis JD. Methods for validating deconvolution analysis of pulsatile hormone release: luteinizing hormone as a paradigm. Methods in Neurosciences 1995; 28:109-29.
488. Mulligan T, Johnson ML, Veldhuis JD. Physiological within-subject variability and test-retest reliability of deconvolution analysis of luteinizing hormone release. Methods in Neurosciences 1995; 28:93-108.
489. Straume M, Veldhuis JD, Johnson ML. Realistic emulation of highly irregular temporal patterns of hormone release: a computer-based pulse simulator. Methods in Neurosciences 1995; 28:220-43.
490. Chen L, Veldhuis JD, Johnson Ml, Straume M. Systems-level analysis of physiological regulatory interactions controlling complex secretory dynamics of the growth hormone axis: a dynamical network model. Methods in Neurosciences 1995; 28:270-310.
491. Johnson ML, Veldhuis JD. Evolution of deconvolution analysis as a hormone pulse detection method. Methods in Neurosciences 1995; 28:1-24.
492. Veldhuis JD, Johnson ML. Specific methodological approaches to selected contemporary issues in deconvolution analysis of pulsatile neuroendocrine data. Methods in Neurosciences 1995; 28:25-92.
493. Veldhuis JD, Evans WS, Johnson ML. Complicating effects of highly correlated model variables on nonlinear least-squares estimates of unique parameter values and their statistical confidence intervals: estimating basal secretion and neurohormone half-life by deconvolution analysis. Methods in Neurosciences 1995; 28:130-8.
494. Veldhuis JD. The neuroendocrine regulation and implications of pulsatile GH secretion: gender effects. Endocrinologist 1995; 5:198-213.
495. Schaefer F, Veldhuis JD, Robertson WR, Dunger D, Scharer K, Cooperative Study Group on Pubertal Development in Chronic Renal Failure. Immunoreactive and bioactive luteinizing hormone in pubertal patients with chronic renal failure. Kidney International 1995; 45:1465-76.
496. Porksen N, Munn S, Steers J, Veldhuis JD, Butler P, Vore S. A pulsatile mode of insulin secretion accounts for approximately seventy percent of total insulin secreted during fasting: direct in vivo measurements of basal versus pulsatile insulin release. Am J Physiol 1995; 269:E478-488.
     View PubMed
497. Veldhuis JD, Johnson ML. Analytical methods for evaluating episodic secretory activity within neuroendocrine axes. Neuroscience & Biobehavioral Reviews 1994 Winter; 18(4):605-12.
     View PubMed
498. van den Berg G, Frolich M, Veldhuis JD, Roelfsema F. Growth hormone secretion in recently operated acromegalic patients. J Clin Endocrinol Metab 1994 Dec; 79(6):1706-15.
     View PubMed
499. Veldhuis JD, Urban RJ, Dufau ML. Differential responses of biologically active luteinizing hormone secretion in older versus young men to interruption of androgen negative feedback. J Clin Endocrinol Metab 1994 Dec; 79(6):1763-70.
     View PubMed
500. Giustina A, Bresciani E, Bossoni S, Chiesa L, Misitano V, Wehrenberg WB, Veldhuis JD. Reciprocal relationship between the level of circulating cortisol and growth hormone secretion in response to growth hormone-releasing hormone in man: studies in patients with adrenal insufficiency. J Clin Endocrinol Metab 1994 Nov; 79(5):1266-72.
     View PubMed
501. Veldhuis JD, Iranmanesh A, Wilkowski MJ, Samojlik E. Neuroendocrine alterations in the somatotropic and lactotropic axes in uremic men. European Journal of Endocrinology 1994 Nov; 131(5):489-98.
     View PubMed
502. Van den Berghe G, de Zegher F, Lauwers P, Veldhuis JD. Luteinizing hormone secretion and hypoandrogenaemia in critically ill men: effect of dopamine. Clin Endocrinol (Oxf) 1994 Nov; 41(5):563-9.
     View PubMed
503. Schaefer F, van Kaick B, Veldhuis JD, Stein G, Scharer K, Robertson WR, Ritz E. Changes in the kinetics and biopotency of luteinizing hormone in hemodialyzed men during treatment with recombinant human erythropoietin. J Am Soc Nephrol 1994 Nov; 5(5):1208-15.
     View PubMed
504. Griffin ML, South SA, Yankov VI, Booth RA Jr, Asplin CM, Veldhuis JD, Evans WS. Insulin-dependent diabetes mellitus and menstrual dysfunction. Ann Med 1994 Oct; 26(5):331-40.
     View PubMed
505. Van den Berghe G, de Zegher F, Lauwers P, Veldhuis JD. Growth hormone secretion in critical illness: effect of dopamine. J Clin Endocrinol Metab 1994 Oct; 79(4):1141-6.
     View PubMed
506. Partsch CJ, Abrahams S, Herholz N, Peter M, Veldhuis JD, Sippell WG. Variability of pulsatile luteinizing hormone secretion in young male volunteers. European Journal of Endocrinology 1994 Sep; 131(3):263-72.
     View PubMed
507. Hartman ML, Pincus SM, Johnson ML, Matthews DH, Faunt LM, Vance ML, Thorner MO, Veldhuis JD. Enhanced basal and disorderly growth hormone secretion distinguish acromegalic from normal pulsatile growth hormone release. J Clin Invest 1994 Sep; 94(3):1277-88.
     View PubMed
508. Loudon AS, Wayne NL, Krieg R, Iranmanesh A, Veldhuis JD, Menaker M. Ultradian endocrine rhythms are altered by a circadian mutation in the Syrian hamster. Endocrinology 1994 Aug; 135(2):712-8.
     View PubMed
509. de Zegher F, Vanhole C, Van den Berghe G, Devlieger H, Eggermont E, Veldhuis JD. Properties of thyroid-stimulating hormone and cortisol secretion by the human newborn on the day of birth. J Clin Endocrinol Metab 1994 Aug; 79(2):576-81.
     View PubMed
510. Sharma OP, Flores JA, Leong DA, Veldhuis JD. Mechanisms by which endothelin-1 stimulates increased cytosolic free calcium ion concentrations in single rat Sertoli cells. Endocrinology 1994 Jul; 135(1):127-34.
     View PubMed
511. Mulligan T, Delemarre-van de Waal HA, Johnson ML, Veldhuis JD. Validation of deconvolution analysis of LH secretion and half-life. Am J Physiol 1994 Jul; 267(1 Pt 2):R202-11.
     View PubMed
512. Veldhuis JD, Iranmanesh A, Lizarralde G, Urban RJ. Combined deficits in the somatotropic and gonadotropic axes in healthy aging men: an appraisal of neuroendocrine mechanisms by deconvolution analysis. Neurobiol Aging 1994 Jul-Aug; 15(4):509-17.
     View PubMed
513. Porksen N, Munn S, Ferguson D, O'Brien T, Veldhuis J, Butler P. Coordinate pulsatile insulin secretion by chronic intraportally transplanted islets in the isolated perfused rat liver. J Clin Invest 1994 Jul; 94(1):219-27.
     View PubMed
514. Schaefer F, Veldhuis JD, Stanhope R, Jones J, Scharer K. Alterations in growth hormone secretion and clearance in peripubertal boys with chronic renal failure and after renal transplantation. Cooperative Study Group of Pubertal development in Chronic Renal Failure. J Clin Endocrinol Metab 1994 Jun; 78(6):1298-306.
     View PubMed
515. Chapman IM, Hartman ML, Straume M, Johnson ML, Veldhuis JD, Thorner MO. Enhanced sensitivity growth hormone (GH) chemiluminescence assay reveals lower postglucose nadir GH concentrations in men than women. J Clin Endocrinol Metab 1994 Jun; 78(6):1312-9.
     View PubMed
516. Schaefer F, Veldhuis JD, Robertson WR, Dunger D, Scharer K. Immunoreactive and bioactive luteinizing hormone in pubertal patients with chronic renal failure. Cooperative Study Group on Pubertal Development in Chronic Renal Failure. Kidney Int 1994 May; 45(5):1465-76.
     View PubMed
517. Diaz-Cueto L, Mendez JP, Barrios-de-Tomasi J, Lee JY, Wide L, Veldhuis JD, Ulloa-Aguirre A. Amplitude regulation of episodic release, in vitro biological to immunological ratio, and median charge of human chorionic gonadotropin in pregnancy. J Clin Endocrinol Metab 1994 Apr; 78(4):890-7.
     View PubMed
518. Sharma OP, Flores JA, Leong DA, Veldhuis JD. Cellular basis for follicle-stimulating hormone-stimulated calcium signaling in single rat Sertoli cells: possible dissociation from effects of adenosine 3',5'-monophosphate. Endocrinology 1994 Apr; 134(4):1915-23.
     View PubMed
519. Weltman A, Weltman JY, Hartman ML, Abbott RD, Rogol AD, Evans WS, Veldhuis JD. Relationship between age, percentage body fat, fitness, and 24-hour growth hormone release in healthy young adults: effects of gender. J Clin Endocrinol Metab 1994 Mar; 78(3):543-8.
     View PubMed
520. Iranmanesh A, Grisso B, Veldhuis JD. Low basal and persistent pulsatile growth hormone secretion are revealed in normal and hyposomatotropic men studied with a new ultrasensitive chemiluminescence assay. J Clin Endocrinol Metab 1994 Mar; 78(3):526-35.
     View PubMed
521. Schaefer F, Daschner M, Veldhuis JD, Oh J, Qadri F, Scharer K. In vivo alterations in the gonadotropin-releasing hormone pulse generator and the secretion and clearance of luteinizing hormone in the uremic castrate rat. Neuroendocrinology 1994 Mar; 59(3):285-96.
     View PubMed
522. Kerrigan JR, Veldhuis JD, Rogol AD. Androgen-receptor blockade enhances pulsatile luteinizing hormone production in late pubertal males: evidence for a hypothalamic site of physiologic androgen feedback action. Pediatr Res 1994 Jan; 35(1):102-6.
     View PubMed
523. Straume M, Veldhuis JD, Johnson ML. Model-independent quantification of measurement error: empirical estimation of discrete variance function profiles based on standard curves. Methods Enzymol 1994; 240:121-50.
     View PubMed
524. Veldhuis JD, Faunt LM, Johnson ML. Analysis of nonequilibrium dynamics of bound, free, and total plasma ligand concentrations over time following nonlinear secretory inputs: kinetics of two or more hormones pulsed into compartments containing multiple variable-affinity binding proteins. Methods Enzymol 1994; 240:349-77.
     View PubMed
525. Veldhuis JD, Johnson ML. Testing pulse detection algorithms with simulations of episodically pulsatile substrate, metabolite, or hormone release. Methods Enzymol 1994; 240:377-415.
     View PubMed
526. Sharma OP, Flores J, Leong DA, Veldhuis JD. Mechanisms by which endothlin-1 stimulates increased cytosolic free calcium ion concentrations in single rat Sertoli cells. Endocrinology 1994; 45:1465-76.
527. Veldhuis JD, Johnson ML, Faunt LM, Seneta E. Assessing temporal coupling between two, or among three or more, neuroendocrine pulse trains: cross-correlation analysis, simulation methods, and conditional probability testing. Methods in Neurosciences 1994; 20:336-76.
528. Veldhuis JD, Moorman J, Johnson ML. Deconvolution analysis of neuroendocrine data: waveform-specific and waveform-independent methods and applications. Methods in Neurosciences 1994; 20:279-325.
529. Mulligan T, Veldhuis JD. Control of gonadotropin secretion. Curr Sci 1994; 4:89-92.
530. Nieves-Rivera F, Kerrigan JR, Krieg RJ Jr, Egan J, Hwang LJ, Truumees E, Veldhuis JD, Evans WS, Rogol AD. Altered growth hormone (GH) secretion in vivo and in vitro in the diabetes-prone BB/Worcester rat. Growth Regul 1993 Dec; 3(4):235-44.
     View PubMed
531. Veldhuis JD, Dufau ML. Steroidal regulation of biologically active luteinizing hormone secretion in men and women. Hum Reprod 1993 Nov; 8 Suppl 2:84-96.
     View PubMed
532. De Zegher F, Van Den Berghe G, Devlieger H, Eggermont E, Veldhuis JD. Dopamine inhibits growth hormone and prolactin secretion in the human newborn. Pediatr Res 1993 Nov; 34(5):642-5.
     View PubMed
533. Challa A, Krieg RJ Jr, Thabet MA, Veldhuis JD, Chan JC. Metabolic acidosis inhibits growth hormone secretion in rats: mechanism of growth retardation. Am J Physiol 1993 Oct; 265(4 Pt 1):E547-53.
     View PubMed
534. Earnhardt RC, Kindler DD, Weaver AM, Cornett G, Elahi D, Veldhuis JD, Hanks JB. Hyperinsulinemia after pancreatic transplantation. Prediction by a novel computer model and in vivo verification. Ann Surg 1993 Oct; 218(4):428-41; discussion 441-3.
     View PubMed
535. Nieves-Rivera F, Rogol AD, Veldhuis JD, Branscom DK, Martha PM Jr, Clarke WL. Alterations in growth hormone secretion and clearance in adolescent boys with insulin-dependent diabetes mellitus. J Clin Endocrinol Metab 1993 Sep; 77(3):638-43.
     View PubMed
536. Metzger DL, Wright NM, Veldhuis JD, Rogol AD, Kerrigan JR. Characterization of pulsatile secretion and clearance of plasma cortisol in premature and term neonates using deconvolution analysis. J Clin Endocrinol Metab 1993 Aug; 77(2):458-63.
     View PubMed
537. Samuels MH, Veldhuis J, Cawley C, Urban RJ, Luther M, Bauer R, Mundy G. Pulsatile secretion of parathyroid hormone in normal young subjects: assessment by deconvolution analysis. J Clin Endocrinol Metab 1993 Aug; 77(2):399-403.
     View PubMed
538. Garmey JC, Day RN, Day KH, Veldhuis JD. Mechanisms of regulation of ovarian sterol metabolism by insulin-like growth factor type II: in vitro studies with swine granulosa cells. Endocrinology 1993 Aug; 133(2):800-8.
     View PubMed
539. Thompson DL, Weltman JY, Rogol AD, Metzger DL, Veldhuis JD, Weltman A. Cholinergic and opioid involvement in release of growth hormone during exercise and recovery. J Appl Physiol 1993 Aug; 75(2):870-8.
     View PubMed
540. Veldhuis JD, Johnson ML, Gallo RV. Reanalysis of the rat proestrous LH surge by deconvolution analysis. Am J Physiol 1993 Jul; 265(1 Pt 2):R240-5.
     View PubMed
541. Holl RW, Schwarz U, Schauwecker P, Benz R, Veldhuis JD, Heinze E. Diurnal variation in the elimination rate of human growth hormone (GH): the half-life of serum GH is prolonged in the evening, and affected by the source of the hormone, as well as by body size and serum estradiol. J Clin Endocrinol Metab 1993 Jul; 77(1):216-20.
     View PubMed
542. Roelfsema F, van den Berg G, Frolich M, Veldhuis JD, van Eijk A, Buurman MM, Etman BH. Sex-dependent alteration in cortisol response to endogenous adrenocorticotropin. J Clin Endocrinol Metab 1993 Jul; 77(1):234-40.
     View PubMed
543. Kerrigan JR, Veldhuis JD, Leyo SA, Iranmanesh A, Rogol AD. Estimation of daily cortisol production and clearance rates in normal pubertal males by deconvolution analysis. J Clin Endocrinol Metab 1993 Jun; 76(6):1505-10.
     View PubMed
544. Kamp GA, Kuilboer MM, Wynne HJ, Rongen-Westerlaken C, Johnson ML, Veldhuis JD, Wit JM. Slow baseline growth and a good response to growth hormone (GH) therapy are related to elevated spontaneous GH pulse frequency in girls with Turner's syndrome. J Clin Endocrinol Metab 1993 Jun; 76(6):1604-9.
     View PubMed
545. Iranmanesh A, Lizarralde G, Veldhuis JD. Coordinate activation of the corticotropic axis by insulin-induced hypoglycemia: simultaneous estimates of beta-endorphin, adrenocorticotropin and cortisol secretion and disappearance in normal men. Acta Endocrinol (Copenh) 1993 Jun; 128(6):521-8.
     View PubMed
546. Flores JA, Garmey JC, Nestler JE, Veldhuis JD. Sites of inhibition of steroidogenesis by activation of protein kinase-C in swine ovarian (granulosa) cells. Endocrinology 1993 May; 132(5):1983-90.
     View PubMed
547. de Zegher F, Devlieger H, Veldhuis JD. Properties of growth hormone and prolactin hypersecretion by the human infant on the day of birth. J Clin Endocrinol Metab 1993 May; 76(5):1177-81.
     View PubMed
548. South SA, Asplin CM, Carlsen EC, Booth RA Jr, Weltman JY, Johnson ML, Veldhuis JD, Evans WS. Alterations in luteinizing hormone secretory activity in women with insulin-dependent diabetes mellitus and secondary amenorrhea. J Clin Endocrinol Metab 1993 Apr; 76(4):1048-53.
     View PubMed
549. Romero G, Garmey JC, Veldhuis JD. The involvement of inositol phosphoglycan mediators in the modulation of steroidogenesis by insulin and insulin-like growth factor-I. Endocrinology 1993 Apr; 132(4):1561-8.
     View PubMed
550. Veldhuis JD, Iranmanesh A, Evans WS, Lizarralde G, Thorner MO, Vance ML. Amplitude suppression of the pulsatile mode of immunoradiometric luteinizing hormone release in fasting-induced hypoandrogenemia in normal men. J Clin Endocrinol Metab 1993 Mar; 76(3):587-93.
     View PubMed
551. Quyyumi SA, Pinkerton JV, Evans WS, Veldhuis JD. Estradiol amplifies the amount of luteinizing hormone (LH) secreted in response to increasing doses of gonadotropin-releasing hormone by specifically augmenting the duration of evoked LH secretory events and hence their mass. J Clin Endocrinol Metab 1993 Mar; 76(3):594-600.
     View PubMed
552. Veldhuis JD, Wilkowski MJ, Zwart AD, Urban RJ, Lizarralde G, Iranmanesh A, Bolton WK. Evidence for attenuation of hypothalamic gonadotropin-releasing hormone (GnRH) impulse strength with preservation of GnRH pulse frequency in men with chronic renal failure. J Clin Endocrinol Metab 1993 Mar; 76(3):648-54.
     View PubMed
553. Kerrigan JR, Martha PM Jr, Veldhuis JD, Blizzard RM, Rogol AD. Altered growth hormone secretory dynamics in prepubertal males with constitutional delay of growth. Pediatr Res 1993 Mar; 33(3):278-83.
     View PubMed
554. Reyes-Fuentes A, Veldhuis JD. Neuroendocrine physiology of the normal male gonadal axis. Endocrinology & Metabolism Clinics of North America 1993 Mar; 22(1):93-124.
     View PubMed
555. Veldhuis JD, Johnson ML, Faunt LM, Mercado M, Baumann G. Influence of the high-affinity growth hormone (GH)-binding protein on plasma profiles of free and bound GH and on the apparent half-life of GH. Modeling analysis and clinical applications. J Clin Invest 1993 Feb; 91(2):629-41.
     View PubMed
556. Hartman ML, Veldhuis JD, Thorner MO. Normal control of growth hormone secretion. Horm Res 1993; 40(1-3):37-47.
     View PubMed
557. Flores JA, Veldhuis JD. Single cell studies of the calcium second-messenger signaling pathway in ovarian granulosa cells. In: Adashi E, Leung PCK, editors. The Ovary. New York: Raven Press; 1993. (Comprehensive endocrinology.). p. 129-45.
558. Hartman ML, Iranmanesh A, Thorner MO, Veldhuis JD. Evaluation of pulsatile patterns of growth hormone release in man: a brief symposial review. American Journal of Human Biology 1993; 5:603-14.
559. de Zegher F, Devlieger H, Eggermont E, Veldhuis JD. Properties of physiological thyroid stimulating hormone hypersecretion in the human newborn. J Clin Endocrinol Metab 1993; 76:1177-81.
     View PubMed
560. Rogol AD, Weltman JY, Evans WS, Veldhuis JD, Weltman AL. Long-term endurance training alters the hypothalamic-pituitary axes for gonadotropins and growth hormone. Endocrinology & Metabolism Clinics of North America 1992 Dec; 21(4):817-32.
     View PubMed
561. Iranmanesh A, Veldhuis JD. Clinical pathophysiology of the somatotropic (GH) axis in adults. Endocrinology & Metabolism Clinics of North America 1992 Dec; 21(4):783-816.
     View PubMed
562. Urban RJ, Dahl KD, Lippert MC, Veldhuis JD. Modulation of immunoradiometric and bioactive follicle stimulating hormone secretion and clearance in young and elderly men during treatment with tamoxifen or flutamide. J Androl 1992 Nov-Dec; 13(6):579-86.
     View PubMed
563. de Zegher F, Devlieger H, Veldhuis JD. Pulsatile and sexually dimorphic secretion of luteinizing hormone in the human infant on the day of birth. Pediatr Res 1992 Nov; 32(5):605-7.
     View PubMed
564. Lampl M, Veldhuis JD, Johnson ML. Saltation and stasis: a model of human growth. Science 1992 Oct 30; 258(5083):801-3.
     View PubMed
565. Kolp LA, Pavlou SN, Urban RJ, Rivier JC, Vale WW, Veldhuis JD. Abrogation by a potent gonadotropin-releasing hormone antagonist of the estrogen/progesterone-stimulated surge-like release of luteinizing hormone and follicle-stimulating hormone in postmenopausal women. J Clin Endocrinol Metab 1992 Oct; 75(4):993-7.
     View PubMed
566. Veldhuis JD, Johnson ML, Lizarralde G, Iranmanesh A. Rhythmic and nonrhythmic modes of anterior pituitary gland secretion. Chronobiol Int 1992 Oct; 9(5):371-9.
     View PubMed
567. Snead DB, Stubbs CC, Weltman JY, Evans WS, Veldhuis JD, Rogol AD, Teates CD, Weltman A. Dietary patterns, eating behaviors, and bone mineral density in women runners. Am J Clin Nutr 1992 Oct; 56(4):705-11.
     View PubMed
568. Wright NM, Northington FJ, Miller JD, Veldhuis JD, Rogol AD. Elevated growth hormone secretory rate in premature infants: deconvolution analysis of pulsatile growth hormone secretion in the neonate. Pediatr Res 1992 Sep; 32(3):286-90.
     View PubMed
569. Flores JA, Quyyumi S, Leong DA, Veldhuis JD. Actions of endothelin-1 on swine ovarian (granulosa) cells. Endocrinology 1992 Sep; 131(3):1350-8.
     View PubMed
570. Veldhuis JD, Urban RJ, Lizarralde G, Johnson ML, Iranmanesh A. Attenuation of luteinizing hormone secretory burst amplitude as a proximate basis for the hypoandrogenism of healthy aging in men. J Clin Endocrinol Metab 1992 Sep; 75(3):707-13.
     View PubMed
571. Evans WS, Weltman JY, Johnson ML, Weltman A, Veldhuis JD, Rogol AD. Effects of opioid receptor blockade on luteinizing hormone (LH) pulses and interpulse LH concentrations in normal women during the early phase of the menstrual cycle. J Endocrinol Invest 1992 Jul-Aug; 15(7):525-31.
     View PubMed
572. Veldhuis JD, Urban RJ, Dufau ML. Evidence that androgen negative feedback regulates hypothalamic gonadotropin-releasing hormone impulse strength and the burst-like secretion of biologically active luteinizing hormone in men. J Clin Endocrinol Metab 1992 Jun; 74(6):1227-35.
     View PubMed
573. Cahan C, Decker MJ, Arnold JL, Washington LH, Veldhuis JD, Goldwasser E, Strohl KP. Diurnal variations in serum erythropoietin levels in healthy subjects and sleep apnea patients. J Appl Physiol 1992 Jun; 72(6):2112-7.
     View PubMed
574. Weltman A, Weltman JY, Schurrer R, Evans WS, Veldhuis JD, Rogol AD. Endurance training amplifies the pulsatile release of growth hormone: effects of training intensity. J Appl Physiol 1992 Jun; 72(6):2188-96.
     View PubMed
575. Snead DB, Weltman A, Weltman JY, Evans WS, Veldhuis JD, Varma MM, Teates CD, Dowling EA, Rogol AD. Reproductive hormones and bone mineral density in women runners. J Appl Physiol 1992 Jun; 72(6):2149-56.
     View PubMed
576. Faria AC, Bekenstein LW, Booth RA Jr, Vaccaro VA, Asplin CM, Veldhuis JD, Thorner MO, Evans WS. Pulsatile growth hormone release in normal women during the menstrual cycle. Clin Endocrinol (Oxf) 1992 Jun; 36(6):591-6.
     View PubMed
577. Vieweg WV, Veldhuis JD, Carey RM. Temporal pattern of renin and aldosterone secretion in men: effects of sodium balance. Am J Physiol 1992 May; 262(5 Pt 2):F871-7.
     View PubMed
578. Apostolakis EM, Longo LD, Veldhuis JD, Yellon SM. Dissociation of pulsatile cortisol and adrenocorticotropin secretion in fetal sheep during late gestation. Endocrinology 1992 May; 130(5):2571-8.
     View PubMed
579. Weltman A, Seip RL, Snead D, Weltman JY, Haskvitz EM, Evans WS, Veldhuis JD, Rogol AD. Exercise training at and above the lactate threshold in previously untrained women. Int J Sports Med 1992 Apr; 13(3):257-63.
     View PubMed
580. Veldhuis JD, Blizzard RM, Rogol AD, Martha PM Jr, Kirkland JL, Sherman BM. Properties of spontaneous growth hormone secretory bursts and half-life of endogenous growth hormone in boys with idiopathic short stature. Genentech Collaborative Group. J Clin Endocrinol Metab 1992 Apr; 74(4):766-73.
     View PubMed
581. Hartman ML, Veldhuis JD, Johnson ML, Lee MM, Alberti KG, Samojlik E, Thorner MO. Augmented growth hormone (GH) secretory burst frequency and amplitude mediate enhanced GH secretion during a two-day fast in normal men. J Clin Endocrinol Metab 1992 Apr; 74(4):757-65.
     View PubMed
582. Flores JA, Leong DA, Veldhuis JD. Is the calcium signal induced by follicle-stimulating hormone in swine granulosa cells mediated by adenosine cyclic 3',5'-monophosphate-dependent protein kinase? Endocrinology 1992 Apr; 130(4):1862-6.
     View PubMed
583. Gordon K, Williams RF, Danforth DR, Veldhuis JD, Hodgen GD. GnRH antagonists suppress prolactin release in non-human primates. Contraception 1992 Apr; 45(4):369-78.
     View PubMed
584. Veldhuis JD, Johnson ML, Seneta E, Iranmanesh A. Temporal coupling among luteinizing hormone, follicle stimulating hormone, beta-endorphin and cortisol pulse episodes in vivo. Acta Endocrinol (Copenh) 1992 Mar; 126(3):193-200.
     View PubMed
585. Iranmanesh A, Lizarralde G, Veldhuis JD. Robustness of the male lactotropic axis to the hyperprolactinemic stimulus of primary thyroidal failure. J Clin Endocrinol Metab 1992 Mar; 74(3):559-64.
     View PubMed
586. Martha PM Jr, Gorman KM, Blizzard RM, Rogol AD, Veldhuis JD. Endogenous growth hormone secretion and clearance rates in normal boys, as determined by deconvolution analysis: relationship to age, pubertal status, and body mass. J Clin Endocrinol Metab 1992 Feb; 74(2):336-44.
     View PubMed
587. Evans WS, Sollenberger MJ, Booth RA Jr, Rogol AD, Urban RJ, Carlsen EC, Johnson ML, Veldhuis JD. Contemporary aspects of discrete peak-detection algorithms. II. The paradigm of the luteinizing hormone pulse signal in women. Endocr Rev 1992 Feb; 13(1):81-104.
     View PubMed
588. Veldhuis JD, Lizarralde G, Iranmanesh A. Divergent effects of short term glucocorticoid excess on the gonadotropic and somatotropic axes in normal men. J Clin Endocrinol Metab 1992 Jan; 74(1):96-102.
     View PubMed
589. Veldhuis JD, Johnson ML. Deconvolution analysis of hormone data. Methods Enzymol 1992; 210:539-75.
     View PubMed
590. Urban RJ, Veldhuis JD. Endocrine control of steroidogenesis in granulosa cells. Oxf Rev Reprod Biol 1992; 14:225-62.
     View PubMed
591. Kuilboer MM, Kleijer B, Kamp GA, Veldhuis JD, Johnson ML, Wit JM. Comparison of four computerized models to estimate 24-hour growth hormone secretion in girls with Turner's syndrome. Horm Res 1992; 38(3-4):125-33.
     View PubMed
592. Rogol AD, Weltman A, Weltman JY, Seip RL, Snead DB, Levine S, Haskvitz EM, Thompson DL, Schurrer R, Dowling E, Walberg-Rankin J, Mueller B, Evans WS, Veldhuis JD. Durability of the reproductive axis in eumenorrheic women during one year of endurance training. Journal of Applied Physiology 1992; 72(4):1571-80.
     View PubMed
593. Veldhuis JD, Johnson ML. Computer-assisted algorithms to analyze pulsatile growth hormone release. Excerpta Medica : International Congress Series 1992; 973:43-57.
594. Veldhuis JD, Evans WS, Butler JP, Johnson ML. Computer algorithms for deconvolution-based assessment of in vivo neuroendocrine secretory events. Methods in Neurosciences 1992; 10:241-77.
595. Veldhuis JD, Johnson ML, Iranmanesh A, Lizarralde G. Rhythmic and non-rhythmic modes of anterior pituitary hormone release in man. In: Touitou Y, Haus E, editors. Biological rhythms in clinical and laboratory medicine. Springer-Verlag; 1992. p. 277-91.
596. Mauras N, Rogol AD, Veldhuis JD. Estrogenic modulation of the gonadotropin-releasing hormone-stimulated secretory activity of the gonadotrope and lactotrope in prepubertal females with Turner's syndrome. J Clin Endocrinol Metab 1991 Dec; 73(6):1202-9.
     View PubMed
597. Iranmanesh A, Lizarralde G, Veldhuis JD. Age and relative adiposity are specific negative determinants of the frequency and amplitude of growth hormone (GH) secretory bursts and the half-life of endogenous GH in healthy men. J Clin Endocrinol Metab 1991 Nov; 73(5):1081-8.
     View PubMed
598. Veldhuis JD, Sotos JF, Sherman BM. Decreased metabolic clearance of endogenous growth hormone and specific alterations in the pulsatile mode of growth hormone secretion occur in prepubertal girls with Turner's syndrome. Genentech Collaborative Group. J Clin Endocrinol Metab 1991 Nov; 73(5):1073-80.
     View PubMed
599. Urban RJ, Padmanabhan V, Beitins I, Veldhuis JD. Metabolic clearance of human follicle-stimulating hormone assessed by radioimmunoassay, immunoradiometric assay, and in vitro Sertoli cell bioassay. J Clin Endocrinol Metab 1991 Oct; 73(4):818-23.
     View PubMed
600. Flores JA, Veldhuis JD, Leong DA. Angiotensin II induces calcium release in a subpopulation of single ovarian (granulosa) cells. Molecular & Cellular Endocrinology 1991 Oct; 81(1-3):1-10.
     View PubMed
601. Nunley WC, Urban RJ, Evans WS, Veldhuis JD. Preservation of pulsatile luteinizing hormone release during postpartum lactational amenorrhea. J Clin Endocrinol Metab 1991 Sep; 73(3):629-36.
     View PubMed
602. Veldhuis JD, Johnson ML, Seneta E. Analysis of the copulsatility of anterior pituitary hormones. J Clin Endocrinol Metab 1991 Sep; 73(3):569-76.
     View PubMed
603. Veldhuis JD, Garmey JC, Urban RJ, Demers LM, Aggarwal BB. Ovarian actions of tumor necrosis factor-alpha (TNF alpha): pleiotropic effects of TNF alpha on differentiated functions of untransformed swine granulosa cells. Endocrinology 1991 Aug; 129(2):641-8.
     View PubMed
604. Veldhuis JD, Johnson ML, Bolton WK. Analyzing pulsatile endocrine data in patients with chronic renal failure: a brief review of deconvolution techniques. Pediatr Nephrol 1991 Jul; 5(4):522-8.
     View PubMed
605. Veldhuis JD. Temporal architecture of in vivo endocrine glandular signaling: obtaining a secretory blueprint by deconvolution analysis. Molecular & Cellular Endocrinology 1991 May; 77(1-3):C63-71.
     View PubMed
606. Holl RW, Hartman ML, Veldhuis JD, Taylor WM, Thorner MO. Thirty-second sampling of plasma growth hormone in man: correlation with sleep stages. J Clin Endocrinol Metab 1991 Apr; 72(4):854-61.
     View PubMed
607. Urban RJ, Johnson ML, Veldhuis JD. In vivo biological validation and biophysical modeling of the sensitivity and positive accuracy of endocrine peak detection. II. The follicle-stimulating hormone pulse signal. Endocrinology 1991 Apr; 128(4):2008-14.
     View PubMed
608. Urban RJ, Garmey JC, Shupnik MA, Veldhuis JD. Follicle-stimulating hormone increases concentrations of messenger ribonucleic acid encoding cytochrome P450 cholesterol side-chain cleavage enzyme in primary cultures of porcine granulosa cells. Endocrinology 1991 Apr; 128(4):2000-7.
     View PubMed
609. Urban RJ, Veldhuis JD, Dufau ML. Estrogen regulates the gonadotropin-releasing hormone-stimulated secretion of biologically active luteinizing hormone. J Clin Endocrinol Metab 1991 Mar; 72(3):660-8.
     View PubMed
610. Nunley WC, Urban RJ, Kitchin JD, Bateman BG, Evans WS, Veldhuis JD. Dynamics of pulsatile prolactin release during the postpartum lactational period. J Clin Endocrinol Metab 1991 Feb; 72(2):287-93.
     View PubMed
611. Guardabasso V, Genazzani AD, Veldhuis JD, Rodbard D. Objective assessment of concordance of secretory events in two endocrine time series. Acta Endocrinol (Copenh) 1991 Feb; 124(2):208-18.
     View PubMed
612. Urban RJ, Veldhuis JD. A selective serotonin reuptake inhibitor, fluoxetine hydrochloride, modulates the pulsatile release of prolactin in postmenopausal women. American Journal of Obstetrics & Gynecology 1991 Jan; 164(1 Pt 1):147-52.
     View PubMed
613. Hartman ML, Faria AC, Vance ML, Johnson ML, Thorner MO, Veldhuis JD. Temporal structure of in vivo growth hormone secretory events in humans. Am J Physiol 1991 Jan; 260(1 Pt 1):E101-10.
     View PubMed
614. Veldhuis JD, Iranmanesh A, Ho KK, Waters MJ, Johnson ML, Lizarralde G. Dual defects in pulsatile growth hormone secretion and clearance subserve the hyposomatotropism of obesity in man. J Clin Endocrinol Metab 1991 Jan; 72(1):51-9.
     View PubMed
615. Iranmanesh A, Lizarralde G, Johnson ML, Veldhuis JD. Nature of altered growth hormone secretion in hyperthyroidism. J Clin Endocrinol Metab 1991 Jan; 72(1):108-15.
     View PubMed
616. Urban RJ, Dahl KD, Padmanabhan V, Beitins IZ, Veldhuis JD. Specific regulatory actions of dihydrotestosterone and estradiol on the dynamics of FSH secretion and clearance in humans. J Androl 1991 Jan-Feb; 12(1):27-35.
     View PubMed
617. Veldhuis JD, Johnson ML, Wilkowski MJ, Iranmanesh A, Bolton WK. Neuroendocrine alterations in the somatotrophic axis in chronic renal failure. Acta Paediatr Scand Suppl 1991; 379:12-22; discussion 23.
     View PubMed
618. Veldhuis JD, Johnson ML. Contemporary aspects of deconvolution analysis to appraise in vivo neuroendocrine secretory events. Frontiers in Neuroendocrinology 1991; 11(4):363-83.
619. Veldhuis JD, Johnson ML. A review and appraisal of deconvolution methods to evaluate in vivo neuroendocrine secretory events. Journal of Neuroendocrinology 1991; 2(6):755-71.
620. Flores JA, Veldhuis JD, Leong DA. Follicle-stimulating hormone evokes an increase in intracellular free calcium ion concentrations in single ovarian (granulosa) cells. Endocrinology 1990 Dec; 127(6):3172-9.
     View PubMed
621. Weltman JY, Veldhuis JD, Weltman A, Kerrigan JR, Evans WS, Rogol AD. Reliability of estimates of pulsatile characteristics of luteinizing hormone and growth hormone release in women. J Clin Endocrinol Metab 1990 Dec; 71(6):1646-52.
     View PubMed
622. Veldhuis JD, Iranmanesh A, Johnson ML, Lizarralde G. Twenty-four-hour rhythms in plasma concentrations of adenohypophyseal hormones are generated by distinct amplitude and/or frequency modulation of underlying pituitary secretory bursts. J Clin Endocrinol Metab 1990 Dec; 71(6):1616-23.
     View PubMed
623. Mauras N, Rogol AD, Veldhuis JD. Increased hGH production rate after low-dose estrogen therapy in prepubertal girls with Turner's syndrome. Pediatr Res 1990 Dec; 28(6):626-30.
     View PubMed
624. Iranmanesh A, Lizarralde G, Short D, Veldhuis JD. Intensive venous sampling paradigms disclose high frequency adrenocorticotropin release episodes in normal men. J Clin Endocrinol Metab 1990 Nov; 71(5):1276-83.
     View PubMed
625. Sollenberger MJ, Carlsen EC, Booth RA Jr, Johnson ML, Veldhuis JD, Evans WS. Nature of gonadotropin-releasing hormone self-priming of luteinizing hormone secretion during the normal menstrual cycle. American Journal of Obstetrics & Gynecology 1990 Nov; 163(5 Pt 1):1529-34.
     View PubMed
626. Urban RJ, Garmey JC, Shupnik MA, Veldhuis JD. Insulin-like growth factor type I increases concentrations of messenger ribonucleic acid encoding cytochrome P450 cholesterol side-chain cleavage enzyme in primary cultures of porcine granulosa cells. Endocrinology 1990 Nov; 127(5):2481-8.
     View PubMed
627. Ulloa-Aguirre A, Blizzard RM, Garcia-Rubi E, Rogol AD, Link K, Christie CM, Johnson ML, Veldhuis JD. Testosterone and oxandrolone, a nonaromatizable androgen, specifically amplify the mass and rate of growth hormone (GH) secreted per burst without altering GH secretory burst duration or frequency or the GH half-life. J Clin Endocrinol Metab 1990 Oct; 71(4):846-54.
     View PubMed
628. Veldhuis JD, Johnson ML, Iranmanesh A, Lizarralde G. Temporal structure of in vivo adrenal secretory activity estimated by deconvolution analysis. J Biol Rhythms 1990 Fall; 5(3):247-55.
     View PubMed
629. Thorner MO, Vance ML, Hartman ML, Holl RW, Evans WS, Veldhuis JD, Van Cauter E, Copinschi G, Bowers CY. Physiological role of somatostatin on growth hormone regulation in humans. Metabolism: Clinical & Experimental 1990 Sep; 39(9 Suppl 2):40-2.
     View PubMed
630. Veldhuis JD. The hypothalamic pulse generator: the reproductive core. Clinical Obstetrics & Gynecology 1990 Sep; 33(3):538-50.
     View PubMed
631. Veldhuis JD, Lassiter AE, Johnson ML. Operating behavior of dual or multiple endocrine pulse generators. Am J Physiol 1990 Sep; 259(3 Pt 1):E351-61.
     View PubMed
632. Veldhuis JD, Iranmanesh A, Johnson ML, Lizarralde G. Amplitude, but not frequency, modulation of adrenocorticotropin secretory bursts gives rise to the nyctohemeral rhythm of the corticotropic axis in man. J Clin Endocrinol Metab 1990 Aug; 71(2):452-63.
     View PubMed
633. Samuels MH, Veldhuis JD, Henry P, Ridgway EC. Pathophysiology of pulsatile and copulsatile release of thyroid-stimulating hormone, luteinizing hormone, follicle-stimulating hormone, and alpha-subunit. J Clin Endocrinol Metab 1990 Aug; 71(2):425-32.
     View PubMed
634. Iranmanesh A, Veldhuis JD, Carlsen EC, Vaccaro VA, Booth RA Jr, Lizarralde G, Asplin CM, Evans WS. Attenuated pulsatile release of prolactin in men with insulin-dependent diabetes mellitus. J Clin Endocrinol Metab 1990 Jul; 71(1):73-8.
     View PubMed
635. Weltman JY, Seip RL, Weltman A, Snead D, Evans WS, Veldhuis JD, Rogol AD. Release of luteinizing hormone and growth hormone after recovery from maximal exercise. J Appl Physiol 1990 Jul; 69(1):196-200.
     View PubMed
636. Veldhuis JD, Johnson ML. An overview of computer algorithms for deconvolution-based assessment of in vivo neuroendocrine secretory events. Biotechniques 1990 Jun; 8(6):634-9.
     View PubMed
637. Urban RJ, Pavlou SN, Rivier JE, Vale WW, Dufau ML, Veldhuis JD. Suppressive actions of a gonadotropin-releasing hormone antagonist on luteinizing hormone, follicle-stimulating hormone, and prolactin release in estrogen-deficient postmenopausal women. American Journal of Obstetrics & Gynecology 1990 May; 162(5):1255-60.
     View PubMed
638. Pavlou SN, Veldhuis JD, Lindner J, Souza KH, Urban RJ, Rivier JE, Vale WW, Stallard DJ. Persistence of concordant luteinizing hormone (LH), testosterone, and alpha-subunit pulses after LH-releasing hormone antagonist administration in normal men. J Clin Endocrinol Metab 1990 May; 70(5):1472-8.
     View PubMed
639. Hartman ML, Veldhuis JD, Vance ML, Faria AC, Furlanetto RW, Thorner MO. Somatotropin pulse frequency and basal concentrations are increased in acromegaly and are reduced by successful therapy. J Clin Endocrinol Metab 1990 May; 70(5):1375-84.
     View PubMed
640. Urban RJ, Veldhuis JD. Effects of short-term stimulation of serotoninergic pathways on the pulsatile secretion of luteinizing hormone in the absence and presence of acute opiate-receptor blockage. J Androl 1990 May-Jun; 11(3):227-32.
     View PubMed
641. Rossmanith WG, Laughlin GA, Mortola JF, Johnson ML, Veldhuis JD, Yen SS. Pulsatile cosecretion of estradiol and progesterone by the midluteal phase corpus luteum: temporal link to luteinizing hormone pulses. J Clin Endocrinol Metab 1990 Apr; 70(4):990-5.
     View PubMed
642. Iranmanesh A, Lizarralde G, Johnson ML, Veldhuis JD. Dynamics of 24-hour endogenous cortisol secretion and clearance in primary hypothyroidism assessed before and after partial thyroid hormone replacement. J Clin Endocrinol Metab 1990 Jan; 70(1):155-61.
     View PubMed
643. Thorner MO, Vance ML, Rogol AD, Blizzard RM, Veldhuis JD, Cauter EV, Copinschi G, Bowers CY. Growth hormone-releasing hormone and growth hormone-releasing peptide as potential therapeutic modalities. Acta Paediatr Scand Suppl 1990; 367:29-32.
     View PubMed
644. Sollenberger ML, Carlson EC, Johnson ML, Veldhuis JD, Evans WS. Specific physiological regulation of LH secretory events throughout the human menstrual cycle: new insights into the pulsatile mode of gonadotropin release. Journal of Neuroendocrinology 1990; 2(6):845-62.
645. Veldhuis JD, Evans WS, Stumpf PG. Mechanisms that subserve estradiol's induction of increased prolactin concentrations: evidence of amplitude modulation of spontaneous prolactin secretory bursts. American Journal of Obstetrics & Gynecology 1989 Nov; 161(5):1149-58.
     View PubMed
646. Mauras N, Rogol AD, Veldhuis JD. Specific, time-dependent actions of low-dose ethinyl estradiol administration on the episodic release of growth hormone, follicle-stimulating hormone, and luteinizing hormone in prepubertal girls with Turner's syndrome. J Clin Endocrinol Metab 1989 Nov; 69(5):1053-8.
     View PubMed
647. Wheeler MB, Veldhuis JD. Facilitative actions of the protein kinase-C effector system on hormonally stimulated adenosine 3',5'-monophosphate production by swine luteal cells. Endocrinology 1989 Nov; 125(5):2414-20.
     View PubMed
648. Veldhuis JD, Urban RJ, Beitins IZ, Blizzard RM, Johnson ML, Dufau ML. Pathophysiological features of the pulsatile secretion of biologically active luteinizing hormone in man. J Steroid Biochem 1989 Oct; 33(4B):739-49.
     View PubMed
649. Martha PM Jr, Rogol AD, Veldhuis JD, Kerrigan JR, Goodman DW, Blizzard RM. Alterations in the pulsatile properties of circulating growth hormone concentrations during puberty in boys. J Clin Endocrinol Metab 1989 Sep; 69(3):563-70.
     View PubMed
650. Asplin CM, Faria AC, Carlsen EC, Vaccaro VA, Barr RE, Iranmanesh A, Lee MM, Veldhuis JD, Evans WS. Alterations in the pulsatile mode of growth hormone release in men and women with insulin-dependent diabetes mellitus. J Clin Endocrinol Metab 1989 Aug; 69(2):239-45.
     View PubMed
651. Veldhuis JD, Iranmanesh A, Lizarralde G, Johnson ML. Amplitude modulation of a burstlike mode of cortisol secretion subserves the circadian glucocorticoid rhythm. Am J Physiol 1989 Jul; 257(1 Pt 1):E6-14.
     View PubMed
652. Urban RJ, Johnson ML, Veldhuis JD. Biophysical modeling of sensitivity and positive accuracy of detecting episodic endocrine signals. Am J Physiol 1989 Jul; 257(1 Pt 1):E88-94.
     View PubMed
653. Iranmanesh A, Lizarralde G, Johnson ML, Veldhuis JD. Circadian, ultradian, and episodic release of beta-endorphin in men, and its temporal coupling with cortisol. J Clin Endocrinol Metab 1989 Jun; 68(6):1019-26.
     View PubMed
654. Veldhuis JD, Gwynne JT. Insulin-like growth factor type I (somatomedin-C) stimulates high density lipoprotein (HDL) metabolism and HDL-supported progesterone biosynthesis by swine granulosa cells in vitro. Endocrinology 1989 Jun; 124(6):3069-76.
     View PubMed
655. Urban RJ, Johnson ML, Veldhuis JD. In vivo biological validation and biophysical modeling of the sensitivity and positive accuracy of endocrine peak detection. I. The LH pulse signal. Endocrinology 1989 May; 124(5):2541-7.
     View PubMed
656. Veldhuis JD, Winters SJ. Nature of alpha subunit secretion in men: circadian rhythms, pulsatile release and secretory profiles. J Androl 1989 May-Jun; 10(3):248-58.
     View PubMed
657. Veldhuis JD, Demers LM. Mechanism(s) by which activation of protein kinase C is coupled to prostacyclin synthesis in granulosa cells. Molecular & Cellular Endocrinology 1989 May; 63(1-2):219-26.
     View PubMed
658. Faria AC, Veldhuis JD, Thorner MO, Vance ML. Half-time of endogenous growth hormone (GH) disappearance in normal man after stimulation of GH secretion by GH-releasing hormone and suppression with somatostatin. J Clin Endocrinol Metab 1989 Mar; 68(3):535-41.
     View PubMed
659. Veldhuis JD, O'Dea LS, Johnson ML. The nature of the gonadotropin-releasing hormone stimulus-luteinizing hormone secretory response of human gonadotrophs in vivo. J Clin Endocrinol Metab 1989 Mar; 68(3):661-70.
     View PubMed
660. Veldhuis JD, Johnson ML, Dufau ML. Physiological attributes of endogenous bioactive luteinizing hormone secretory bursts in man. Am J Physiol 1989 Feb; 256(2 Pt 1):E199-207.
     View PubMed
661. Iranmanesh A, Veldhuis JD, Johnson ML, Lizarralde G. 24-hour pulsatile and circadian patterns of cortisol secretion in alcoholic men. J Androl 1989 Jan-Feb; 10(1):54-63.
     View PubMed
662. Wheeler MB, Veldhuis JD. Purification of three forms of chromatographically distinct protein kinase C from the swine ovary. Molecular & Cellular Endocrinology 1989 Jan; 61(1):117-22.
     View PubMed
663. Veldhuis JD, Iranmanesh A, Clarke I, Kaiser DL, Johnson ML. Random and non-random coincidence between luteinizing hormone peaks and follicle-stimulating hormone, alpha subunit, prolactin, and gonadotropin-releasing hormone pulsations. Journal of Neuroendocrinology 1989; 1:185-94.
664. Yoshida K, Veldhuis JD. Hormonal modulation of low density lipoprotein in metabolism by mammalian granulosa cells. Advances in Contraceptive Delivery Systems 1989; 6:95-119.
665. Veldhuis JD, Dufau ML. Clinical pathophysiology of bioactive luteinizing hormone secretion in man. Serono Symposia Publications from Raven Press 1989; 62:237-63.
666. Vieweg WVR, David JJ, Rowe WT, Peach MJ, Veldhuis JD, Kaiser DL, Spradlin WW. Correlation of parameters of urinary excretion with serum osmolality among patients with psychosis, intermittent hyponatremia, and polydipsia (PIP). Psychiatric Medicine 1989; 6:81-97.
667. Veldhuis JD, Johnson ML. A novel general biophysical model for simulating episodic endocrine gland signaling. Am J Physiol 1988 Dec; 255(6 Pt 1):E749-59.
     View PubMed
668. Urban RJ, Davis MR, Rogol AD, Johnson ML, Veldhuis JD. Acute androgen receptor blockade increases luteinizing hormone secretory activity in men. J Clin Endocrinol Metab 1988 Dec; 67(6):1149-55.
     View PubMed
669. Wheeler MB, Veldhuis JD. Interactions of protein kinase C with receptor- and non-receptor-mediated cyclic AMP generation in swine granulosa cells. Molecular & Cellular Endocrinology 1988 Oct; 59(3):195-203.
     View PubMed
670. Veldhuis JD. Follicle-stimulating hormone regulates low density lipoprotein metabolism by swine granulosa cells. Endocrinology 1988 Sep; 123(3):1660-7.
     View PubMed
671. Veldhuis JD, Johnson ML. Operating characteristics of the hypothalamo-pituitary-gonadal axis in men: circadian, ultradian, and pulsatile release of prolactin and its temporal coupling with luteinizing hormone. J Clin Endocrinol Metab 1988 Jul; 67(1):116-23.
     View PubMed
672. Veldhuis JD, Johnson ML. In vivo dynamics of luteinizing hormone secretion and clearance in man: assessment by deconvolution mechanics. J Clin Endocrinol Metab 1988 Jun; 66(6):1291-300.
     View PubMed
673. Veldhuis JD, Rodgers RJ, Hewlett EL. Actions of cyclic adenosine monophosphate on the cytodifferentiation of ovarian cells: studies in cultured swine granulosa cells using a novel exogenous adenylate cyclase from Bordetella pertussis. Mol Endocrinol 1988 Jun; 2(6):499-506.
     View PubMed
674. Iranmanesh A, Veldhuis JD, Samojlik E, Rogol AD, Johnson ML, Lizarralde G. Alterations in the pulsatile properties of gonadotropin secretion in alcoholic men. J Androl 1988 May-Jun; 9(3):207-14.
     View PubMed
675. Urban RJ, Veldhuis JD, Blizzard RM, Dufau ML. Attenuated release of biologically active luteinizing hormone in healthy aging men. J Clin Invest 1988 Apr; 81(4):1020-9.
     View PubMed
676. Ho KY, Veldhuis JD, Johnson ML, Furlanetto R, Evans WS, Alberti KG, Thorner MO. Fasting enhances growth hormone secretion and amplifies the complex rhythms of growth hormone secretion in man. J Clin Invest 1988 Apr; 81(4):968-75.
     View PubMed
677. Veldhuis JD, Evans WS, Urban RJ, Rogol AD, Johnson ML. Physiologic attributes of the luteinizing hormone pulse signal in the human. Cross-validation studies in men. J Androl 1988 Mar-Apr; 9(2):69-77.
     View PubMed
678. Veldhuis JD, Christiansen E, Evans WS, Kolp LA, Rogol AD, Johnson ML. Physiological profiles of episodic progesterone release during the midluteal phase of the human menstrual cycle: analysis of circadian and ultradian rhythms, discrete pulse properties, and correlations with simultaneous luteinizing hormone release. J Clin Endocrinol Metab 1988 Feb; 66(2):414-21.
     View PubMed
679. Urban RJ, Kaiser DL, van Cauter E, Johnson ML, Veldhuis JD. Comparative assessments of objective peak-detection algorithms. II. Studies in men. Am J Physiol 1988 Jan; 254(1 Pt 1):E113-9.
     View PubMed
680. Vieweg WV, David JJ, Rowe WT, Peach MJ, Veldhuis JD, Kaiser DL, Spradlin WW. Correlation of parameters of urinary excretion with serum osmolality among patients with psychosis, intermittent hyponatremia, and polydipsia (PIP syndrome). Psychiatr Med 1988; 6(1):81-97.
     View PubMed
681. Veldhuis JD, Faria A, Vance ML, Evans WS, Thorner MO, Johnson ML. Contemporary tools for the analysis of episodic growth hormone secretion and clearance in vivo. Acta Paediatr Scand Suppl 1988; 347:63-82.
     View PubMed
682. Urban RJ, Evans WS, Rogol AD, Kaiser DL, Johnson ML, Veldhuis JD. Contemporary aspects of discrete peak detection algorithms: I. The paradigm of the luteinizing hormone pulse signal in men. Endocrine Reviews 1988; 9:3-37.
     View PubMed
683. Veldhuis JD, Urban RJ, Sollenberger MJ, Evans WS, Rogol AD, Johnson ML. Neuroendocrine regulation of the human gonadotropin-releasing hormone (GnRH) pulse generator. Progress in Endocrinology 1988; 1:433-41.
684. Urban RJ, Pavlou SN, Rivier JE, Vale WW, Dufau ML, Veldhuis JD. Increased potency and sustained suppressive actions of a new gonadotropin-releasing hormone (GnRH) antagonist peptide in man. Trans Assoc Am Physicians 1988; 101:302-9.
     View PubMed
685. Bellin ME, Veldhuis JD, Ax RL. Follicular fluid glycosaminoglycans inhibit degradation of low-density lipoproteins and progesterone production by porcine granulosa cells. Biol Reprod 1987 Dec; 37(5):1179-84.
     View PubMed
686. Veldhuis JD. Prostaglandin F2 alpha initiates polyphosphatidylinositol hydrolysis and membrane translocation of protein kinase C in swine ovarian cells. Biochem Biophys Res Commun 1987 Nov 30; 149(1):112-7.
     View PubMed
687. Veldhuis JD, Carlson ML, Johnson ML. The pituitary gland secretes in bursts: appraising the nature of glandular secretory impulses by simultaneous multiple-parameter deconvolution of plasma hormone concentrations. Proc Natl Acad Sci U S A 1987 Nov; 84(21):7686-90.
     View PubMed
688. Veldhuis JD, King JC, Urban RJ, Rogol AD, Evans WS, Kolp LA, Johnson ML. Operating characteristics of the male hypothalamo-pituitary-gonadal axis: pulsatile release of testosterone and follicle-stimulating hormone and their temporal coupling with luteinizing hormone. J Clin Endocrinol Metab 1987 Nov; 65(5):929-41.
     View PubMed
689. Kulin HE, Demers LM, Rogol AD, Veldhuis JD. The effect of long-term opiate antagonist administration to pubertal boys. J Androl 1987 Nov-Dec; 8(6):374-7.
     View PubMed
690. Veldhuis JD, Dufau ML. Estradiol modulates the pulsatile secretion of biologically active luteinizing hormone in man. J Clin Invest 1987 Sep; 80(3):631-8.
     View PubMed
691. Veldhuis JD. Pathophysiologic features of episodic gonadotropin secretion in man. Am J Med Sci 1987 Sep; 294(3):150-60.
     View PubMed
692. Christiansen E, Veldhuis JD, Rogol AD, Stumpf P, Evans WS. Modulating actions of estradiol on gonadotropin-releasing hormone-stimulated prolactin secretion in postmenopausal individuals. American Journal of Obstetrics & Gynecology 1987 Aug; 157(2):320-5.
     View PubMed
693. Mauras N, Rogol AD, Veldhuis JD. Appraising the instantaneous secretory rates of luteinizing hormone and testosterone in response to selective mu opiate receptor blockade in late pubertal boys. J Androl 1987 Jul-Aug; 8(4):203-9.
     View PubMed
694. Veldhuis JD, Nestler JE, Strauss JF 3rd. The insulin-like growth factor, somatomedin-C, modulates low density lipoprotein metabolism by swine granulosa cells. Endocrinology 1987 Jul; 121(1):340-6.
     View PubMed
695. Veldhuis JD, Rodgers RJ. Mechanisms subserving the steroidogenic synergism between follicle-stimulating hormone and insulin-like growth factor I (somatomedin C). Alterations in cellular sterol metabolism in swine granulosa cells. J Biol Chem 1987 Jun 5; 262(16):7658-64.
     View PubMed
696. Davis MR, Veldhuis JD, Rogol AD, Dufau ML, Catt KJ. Sustained inhibitory actions of a potent antagonist of gonadotropin-releasing hormone in postmenopausal women. J Clin Endocrinol Metab 1987 Jun; 64(6):1268-74.
     View PubMed
697. Veldhuis JD, Johnson ML, Dufau ML. Preferential release of bioactive luteinizing hormone in response to endogenous and low dose exogenous gonadotropin-releasing hormone pulses in man. J Clin Endocrinol Metab 1987 Jun; 64(6):1275-82.
     View PubMed
698. Veldhuis JD, Demers LM. Activation of protein kinase C is coupled to prostaglandin E2 synthesis in swine granulosa cells. Prostaglandins 1987 Jun; 33(6):819-29.
     View PubMed
699. Veldhuis JD, Guardabasso V, Rogol AD, Evans WS, Oerter KE, Johnson ML, Rodbard D. Appraising the nature of luteinizing hormone secretory events in men. Am J Physiol 1987 May; 252(5 Pt 1):E599-605.
     View PubMed
700. Evans WS, Faria AC, Christiansen E, Ho KY, Weiss J, Rogol AD, Johnson ML, Blizzard RM, Veldhuis JD, Thorner MO. Impact of intensive venous sampling on characterization of pulsatile GH release. Am J Physiol 1987 Apr; 252(4 Pt 1):E549-56.
     View PubMed
701. Reiter EO, Biggs DE, Veldhuis JD, Beitins IZ. Pulsatile release of bioactive luteinizing hormone in prepubertal girls: discordance with immunoreactive luteinizing hormone pulses. Pediatr Res 1987 Apr; 21(4):409-13.
     View PubMed
702. Wheeler MB, Veldhuis JD. Catalytic and receptor-binding properties of the calcium-sensitive phospholipid-dependent protein kinase (protein kinase C) in swine luteal cytosol. Molecular & Cellular Endocrinology 1987 Mar; 50(1-2):123-9.
     View PubMed
703. Veldhuis JD, Evans WS, Rogol AD, Thorner MO, Stumpf P. Actions of estradiol on discrete attributes of the luteinizing hormone pulse signal in man. Studies in postmenopausal women treated with pure estradiol. J Clin Invest 1987 Mar; 79(3):769-76.
     View PubMed
704. Mauras N, Blizzard RM, Link K, Johnson ML, Rogol AD, Veldhuis JD. Augmentation of growth hormone secretion during puberty: evidence for a pulse amplitude-modulated phenomenon. J Clin Endocrinol Metab 1987 Mar; 64(3):596-601.
     View PubMed
705. Veldhuis JD, Demers LM. Activation of protein kinase C is coupled to prostaglandin F2 alpha synthesis in the ovary: studies in cultured swine granulosa cells. Molecular & Cellular Endocrinology 1987 Feb; 49(2-3):249-54.
     View PubMed
706. Dufau ML, Veldhuis JD. Pathophysiological relationships between the biological and immunological activities of luteinizing hormone. Baillieres Clinical Endocrinology & Metabolism 1987 Feb; 1(1):153-76.
     View PubMed
707. Veldhuis JD. Mechanisms subserving hormone action in the ovary: role of calcium ions as assessed by steady state calcium exchange in cultured swine granulosa cells. Endocrinology 1987 Feb; 120(2):445-9.
     View PubMed
708. Veldhuis JD, Yoshida K, DuBois W, Fields MJ. Maitotoxin stimulates steroid and peptide hormone secretion by swine luteal tissue. Am J Physiol 1987 Jan; 252(1 Pt 1):E8-12.
     View PubMed
709. Ho KY, Evans WS, Blizzard RM, Veldhuis JD, Merriam GR, Samojlik E, Furlanetto R, Rogol AD, Kaiser DL, Thorner MO. Effects of sex and age on the 24-hour profile of growth hormone secretion in man: importance of endogenous estradiol concentrations. J Clin Endocrinol Metab 1987 Jan; 64(1):51-8.
     View PubMed
710. Veldhuis JD. Contemporary insights into the regulation of luteinizing hormone secretion in man. Horm Res 1987; 28(2-4):126-38.
     View PubMed
711. Demers LM, Veldhuis JD. A stimulatory role for the protein kinase C pathway in ovarian prostaglandin synthesis: studies with cultured swine granulosa cells. Advances in Prostaglandin, Thromboxane, & Leukotriene Research 1987; 17B:1117-21.
712. Davis M, Nassberg B, Borges JLC, Iranmanesh A, Lizzaralde G, Santen RJ, Drake CR, Rogol AD, Kaiser DL, Thorner MO, Veldhuis JD. Actions of calcium ions and a calcium-influx blocker on basal and TRH- and GnRH-stimulated hormone release in patients with pituitary adenomas. Journal of Endocrinological Investigation 1987; 10:427-33.
     View PubMed
713. Veldhuis JD. Pathophysiological features of episodic gonadotropin secretion in man. Clin Res 1987; 35(1):12A.
714. Veldhuis JD, Demers LM. An inhibitory role for the protein kinase C pathway in ovarian steroidogenesis. Studies with cultured swine granulosa cells. Biochem J 1986 Nov 1; 239(3):505-11.
     View PubMed
715. Veldhuis JD, Rodgers RJ, Furlanetto RW. Synergistic actions of estradiol and the insulin-like growth factor somatomedin-C on swine ovarian (granulosa) cells. Endocrinology 1986 Aug; 119(2):530-8.
     View PubMed
716. Veldhuis JD, Samojlik E, Evans WS, Rogol AD, Ridgeway CE, Crowley WF, Kolp L, Checinska E, Kirschner MA, Thorner MO, et al. Endocrine impact of pure estradiol replacement in postmenopausal women: alterations in anterior pituitary hormone release and circulating sex steroid hormone concentrations. American Journal of Obstetrics & Gynecology 1986 Aug; 155(2):334-9.
     View PubMed
717. Veldhuis JD, Nestler JE, Strauss JF 3rd, Gwynne JT. Insulin regulates low density lipoprotein metabolism by swine granulosa cells. Endocrinology 1986 Jun; 118(6):2242-53.
     View PubMed
718. Mauras N, Veldhuis JD, Rogol AD. Role of endogenous opiates in pubertal maturation: opposing actions of naltrexone in prepubertal and late pubertal boys. J Clin Endocrinol Metab 1986 Jun; 62(6):1256-63.
     View PubMed
719. Veldhuis JD, Evans WS, Rogol AD, Kolp L, Thorner MO, Stumpf P. Pituitary self-priming actions of gonadotropin-releasing hormone. Kinetics of estradiol's potentiating effects on gonadotropin-releasing hormone-facilitated luteinizing hormone and follicle-stimulating hormone release in healthy postmenopausal women. J Clin Invest 1986 Jun; 77(6):1849-56.
     View PubMed
720. Veldhuis JD, Evans WS, Johnson ML, Wills MR, Rogol AD. Physiological properties of the luteinizing hormone pulse signal: impact of intensive and extended venous sampling paradigms on its characterization in healthy men and women. J Clin Endocrinol Metab 1986 May; 62(5):881-91.
     View PubMed
721. Veldhuis JD. Mechanisms subserving the bipotential actions of estrogen on ovarian cells: studies with a selective anti-estrogen, LY156758, and the sparingly metabolizable estrogen agonist, moxestrol. J Steroid Biochem 1986 May; 24(5):977-82.
     View PubMed
722. Veldhuis JD, Fraioli F, Rogol AD, Dufau ML. Metabolic clearance of biologically active luteinizing hormone in man. J Clin Invest 1986 Apr; 77(4):1122-8.
     View PubMed
723. Veldhuis JD, Johnson ML. Cluster analysis: a simple, versatile, and robust algorithm for endocrine pulse detection. Am J Physiol 1986 Apr; 250(4 Pt 1):E486-93.
     View PubMed
724. Perkins SN, Cronin MJ, Veldhuis JD. Properties of beta-adrenergic receptors on porcine corpora lutea and granulosa cells. Endocrinology 1986 Mar; 118(3):998-1005.
     View PubMed
725. Vieweg WV, David JJ, Rowe WT, Peach MJ, Veldhuis JD, Spradlin WW. Correlation of cigarette-induced increase in serum nicotine levels with arginine vasopressin concentrations in the syndrome of self-induced water intoxication and psychosis (SIWIP). Can J Psychiatry 1986 Mar; 31(2):108-11.
     View PubMed
726. Veldhuis JD, Rogol AD, Evans WS, Iranmanesh A, Lizarralde G, Johnson ML. Spectrum of the pulsatile characteristics of LH release in normal men. J Androl 1986 Mar-Apr; 7(2):83-92.
     View PubMed
727. Veldhuis JD, Rodgers RJ, Dee A, Simpson ER. The insulin-like growth factor, somatomedin C, induces the synthesis of cholesterol side-chain cleavage cytochrome P-450 and adrenodoxin in ovarian cells. J Biol Chem 1986 Feb 25; 261(6):2499-502.
     View PubMed
728. Brunt LM, Veldhuis JD, Dilley WG, Farndon JR, Santen RJ, Leight GS, Wells SA Jr. Stimulation of insulin secretion by a rapid intravenous calcium infusion in patients with beta-cell neoplasms of the pancreas. J Clin Endocrinol Metab 1986 Jan; 62(1):210-6.
     View PubMed
729. Veldhuis JD, Dufau ML. Actions of estradiol on the pulsatile secretion of bioactive luteinizing hormone in man. Trans Assoc Am Physicians 1986; 99:236-44.
     View PubMed
730. Veldhuis JD, Weiss J, Mauras N, Rogol AD, Evans WS, Johnson ML. Appraising endocrine pulse signals at low circulating hormone concentrations: Use of regional coefficients of variation in the experimental series to analyze pulsatile luteinizing hormone release. Pediatric Research 1986; 20:632-7.
     View PubMed
731. Vieweg WV, David JJ, Rowe WT, Peach MJ, Veldhuis JD, Kaiser DL, Spradlin WW. Psychogenic polydipsia and water intoxication--concepts that have failed. Biol Psychiatry 1985 Dec; 20(12):1308-20.
     View PubMed
732. Veldhuis JD, Gwynne JT. Estrogen regulates low density lipoprotein metabolism by cultured swine granulosa cells. Endocrinology 1985 Oct; 117(4):1321-7.
     View PubMed
733. Veldhuis JD, Rogol AD, Perez-Palacios G, Stumpf P, Kitchin JD, Dufau ML. Endogenous opiates participate in the regulation of pulsatile luteinizing hormone release in an unopposed estrogen milieu: studies in estrogen-replaced, gonadectomized patients with testicular feminization. J Clin Endocrinol Metab 1985 Oct; 61(4):790-3.
     View PubMed
734. Veldhuis JD, Hewlett EL. Evidence for a functionally active inhibitory guanine nucleotide-binding regulatory protein in the swine ovary. Biochem Biophys Res Commun 1985 Sep 30; 131(3):1168-74.
     View PubMed
735. Veldhuis JD, Evans WS, Demers LM, Thorner MO, Wakat D, Rogol AD. Altered neuroendocrine regulation of gonadotropin secretion in women distance runners. J Clin Endocrinol Metab 1985 Sep; 61(3):557-63.
     View PubMed
736. Veldhuis JD, Gwynne JT. Properties of low density lipoprotein binding by cultured swine granulosa cells. Endocrinology 1985 Sep; 117(3):1067-75.
     View PubMed
737. Veldhuis JD. Bipotential actions of estrogen on progesterone biosynthesis by ovarian cells. II. Relation of estradiol's stimulatory actions to cholesterol and progestin metabolism in cultured swine granulosa cells. Endocrinology 1985 Sep; 117(3):1076-83.
     View PubMed
738. Veldhuis JD, Demers LM. A role for somatomedin C as a differentiating hormone and amplifier of hormone action on ovarian cells: studies with synthetically pure human somatomedin C and swine granulosa cells. Biochem Biophys Res Commun 1985 Jul 16; 130(1):234-40.
     View PubMed
739. Beitins IZ, Barkan A, Klibanski A, Kyung N, Reppert SM, Badger TM, Veldhuis J, McArthur JW. Hormonal responses to short term fasting in postmenopausal women. J Clin Endocrinol Metab 1985 Jun; 60(6):1120-6.
     View PubMed
740. Veldhuis JD, Sowers JR, Rogol AD, Klein FA, Miller N, Dufau ML. Pathophysiology of male hypogonadism associated with endogenous hyperestrogenism. Evidence for dual defects in the gonadal axis. N Engl J Med 1985 May 23; 312(21):1371-5.
     View PubMed
741. Veldhuis JD. Bipotential actions of estrogen on progesterone biosynthesis by ovarian cells. I. Relation of estradiol's inhibitory actions to cholesterol and progestin metabolism in cultured swine granulosa cells. Endocrinology 1985 May; 116(5):1818-25.
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742. Veldhuis JD, Furlanetto RW. Trophic actions of human somatomedin C/insulin-like growth factor I on ovarian cells: in vitro studies with swine granulosa cells. Endocrinology 1985 Apr; 116(4):1235-42.
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743. Veldhuis JD, Rogol AD, Johnson ML. Minimizing false-positive errors in hormonal pulse detection. Am J Physiol 1985 Apr; 248(4 Pt 1):E475-81.
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744. Veldhuis JD, Kolp LA. Mechanisms subserving insulin's differentiating actions on progestin biosynthesis by ovarian cells: studies with cultured swine granulosa cells. Endocrinology 1985 Feb; 116(2):651-9.
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745. Veldhuis JD, Strauss JF 3rd, Silavin SL, Kolp LA. The role of cholesterol esterification in ovarian steroidogenesis: studies in cultured swine granulosa cells using a novel inhibitor of acyl coenzyme A: cholesterol acyltransferase. Endocrinology 1985 Jan; 116(1):25-30.
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746. Veldhuis JD, Borges JL, Drake CR, Rogol AD, Kaiser DL, Thorner MO. Divergent influences of the structurally dissimilar calcium entry blockers, diltiazem and verapamil, on thyrotropin- and gonadotropin-releasing hormone-stimulated anterior pituitary hormone secretion in man. J Clin Endocrinol Metab 1985 Jan; 60(1):144-9.
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747. Veldhuis JD, Evans WS, Rogol AD, Drake CR, Thorner MO, Merriam GR, Johnson ML. Performance of LH pulse-detection algorithms at rapid rates of venous sampling in humans. Am J Physiol 1984 Oct; 247(4 Pt 1):E554-63.
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748. Veldhuis JD, Evans WS, Rogol AD, Drake CR, Thorner MO, Merriam GR, Johnson ML. Intensified rates of venous sampling unmask the presence of spontaneous, high-frequency pulsations of luteinizing hormone in man. J Clin Endocrinol Metab 1984 Jul; 59(1):96-102.
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749. Veldhuis JD, Borges JL, Drake CR, Rogol AD. Divergent influences of calcium ions on releasing factor-stimulated anterior pituitary hormone secretion in normal man. J Clin Endocrinol Metab 1984 Jul; 59(1):56-61.
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750. Veldhuis JD, Rogol AD, Samojlik E, Ertel NH. Role of endogenous opiates in the expression of negative feedback actions of androgen and estrogen on pulsatile properties of luteinizing hormone secretion in man. J Clin Invest 1984 Jul; 74(1):47-55.
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751. de Jongh BM, Veldhuis JD, Drop SL, Nijenhuis LE, Dupont B. Linkage and segregation analysis of HLA and congenital hypoaldosteronism due to corticosterone methyl-oxydase deficiency type I and type II. Tissue Antigens 1984 Jul; 24(1):18-24.
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752. Veldhuis JD, Beitins IZ, Johnson ML, Serabian MA, Dufau ML. Biologically active luteinizing hormone is secreted in episodic pulsations that vary in relation to stage of the menstrual cycle. J Clin Endocrinol Metab 1984 Jun; 58(6):1050-8.
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753. Veldhuis JD, Gwynne JT, Strauss JF 3rd, Demers LM. Role of estradiol as a biological amplifier of gonadotropin action in the ovary: in vitro studies using swine granulosa cells and homologous lipoproteins. Endocrinology 1984 Jun; 114(6):2312-22.
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754. Veldhuis JD, Tamura S, Kolp L, Furlanetto RW, Larner J. Mechanisms subserving insulin action in the gonad: evidence that insulin induces specific phosphorylation of its immunoprecipitable receptor on ovarian cells. Biochem Biophys Res Commun 1984 Apr 16; 120(1):144-9.
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755. Veldhuis JD, Klase PA, Demers LM, Chafouleas JG. Mechanisms subserving calcium's modulation of luteinizing hormone action in isolated swine granulosa cells. Endocrinology 1984 Feb; 114(2):441-9.
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756. Rogol AD, Veldhuis JD, Williams FA, Johnson ML. Pulsatile secretion of gonadotropins and prolactin in male marathon runners. Relation to the endogenous opiate system. J Androl 1984 Jan-Feb; 5(1):21-7.
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757. Veldhuis JD. Calcium-influx blockers in the therapy of esophageal motor disorders. Internal Medicine for the Specialist 1984; 5:161-9.
758. Veldhuis JD, Rogol AD, Johnson ML, Dufau ML. Modulation of the pulsatile release of biologically active luteinizing hormone by endogenous opiates. Ann N Y Acad Sci 1984; 438:485-9.
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759. Veldhuis JD, Rogol AD, Johnson ML. Endogenous opiates modulate the pulsatile secretion of biologically active luteinizing hormone in man. J Clin Invest 1983 Dec; 72(6):2031-40.
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760. Veldhuis JD, Rogol AD, Williams FA, Johnson ML. Do alpha-adrenergic mechanisms regulate spontaneous or opiate-modulated pulsatile luteinizing hormone secretion in man? J Clin Endocrinol Metab 1983 Dec; 57(6):1292-6.
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761. Dufau ML, Veldhuis JD, Fraioli F, Johnson ML, Beitins IZ. Mode of secretion of bioactive luteinizing hormone in man. J Clin Endocrinol Metab 1983 Nov; 57(5):993-1000.
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762. Veldhuis JD, Kolp LA, Toaff ME, Strauss JF 3rd, Demers LM. Mechanisms subserving the trophic actions of insulin on ovarian cells. In vitro studies using swine granulosa cells. J Clin Invest 1983 Sep; 72(3):1046-57.
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763. Veldhuis JD, Klase PA, Sandow BA, Kolp LA. Progesterone secretion by highly differentiated human granulosa cells isolated from preovulatory Graafian follicles induced by exogenous gonadotropins and human chorionic gonadotropin. J Clin Endocrinol Metab 1983 Jul; 57(1):87-93.
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764. Veldhuis JD, Kulin HE, Wilson TE, Melby JC. Detection of isolated aldosterone deficiency in the neonate. J Pediatr 1983 Jan; 102(1):83-5.
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765. Worgul TJ, Santen RJ, Samojlik E, Veldhuis JD, Lipton A, Harvey HA, Drago JR, Rohner TJ. Clinical and biochemical effect of aminoglutethimide in the treatment of advanced prostatic carcinoma. J Urol 1983 Jan; 129(1):51-5.
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766. Rogol AD, Veldhuis JD, Williams FT, Johnson ML. Pulsatile secretion of gonadotropins and prolactin in male marathon runners: relation to the endogenous opiate system. J Andrology 1983; 5:21-7.
767. Veldhuis JD, Monsaert RM, Warner BO. Gonadotropin and prolactin secretion in Cushing's disease: responses to infusion of the opiate-receptor antagonist, naloxone. Neuroendocrinol Lett 1983; 5:15-9.
768. Veldhuis JD, Kulin HE, Warner BA, Santner SJ. Responsiveness of gonadotropin secretion to infusion of an opiate-receptor antagonist in hypogonadotropic individuals. J Clin Endocrinol Metab 1982 Oct; 55(4):649-53.
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769. Veldhuis JD, Klase PA, Strauss JF 3rd, Hammond JM. Facilitative interactions between estradiol and luteinizing hormone in the regulation of progesterone production by cultured swine granulosa cells: relation to cellular cholesterol metabolism. Endocrinology 1982 Aug; 111(2):441-7.
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770. Santen RJ, Santner SJ, Tilsen-Mallett N, Rosen HR, Samojlik E, Veldhuis JD. In vivo and in vitro pharmacological studies of aminoglutethimide as an aromatase inhibitor. Cancer Res 1982 Aug; 42(8 Suppl):3353s-3359s.
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771. Veldhuis JD, Klase PA. Mechanisms by which calcium ions regulate the steroidogenic actions of luteinizing hormone in isolated ovarian cells in vitro. Endocrinology 1982 Jul; 111(1):1-6.
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772. Veldhuis JD, Klase PA, Strauss JF 3rd, Hammond JM. The role of estradiol as a biological amplifier of the actions of follicle-stimulating hormone: in vitro studies in swine granulosa cells. Endocrinology 1982 Jul; 111(1):144-51.
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773. Veldhuis JD. Regulation of ovarian ornithine decarboxylase. Role of Calcium ions in enzyme induction in isolated swine granulosa cells in vitro. Biochim Biophys Acta 1982 Apr 29; 720(2):211-6.
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774. Ellingboe J, Veldhuis JD, Mendelson JH, Kuehnle JC, Mello NK. Effect of endogenous opioid blockade on the amplitude and frequency of pulsatile luteinizing hormone secretion in normal men. J Clin Endocrinol Metab 1982 Apr; 54(4):854-7.
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775. Veldhuis JD, Klase P, Demers LM. Luteinizing hormone stimulates the production of prostacyclin by isolated ovarian cell in vitro. Prostaglandins 1982 Mar; 23(3):319-27.
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776. Veldhuis JD, Klase PA. Calcium ions modulate hormonally stimulated progesterone production in isolated ovarian cells. Biochem J 1982 Feb 15; 202(2):381-6.
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777. Veldhuis JD, Klase PA. Role of calcium ions in the stimulatory actions of luteinizing hormone in isolated ovarian cells: studies with divalent-cation ionophores. Biochem Biophys Res Commun 1982 Jan 29; 104(2):603-10.
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778. Hammond JM, Veldhuis JD, Seale TW, Rechler MM. Intraovarian regulation of granulosa-cell replication. Adv Exp Med Biol 1982; 147:341-56.
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779. Santen RJ, Santner SJ, Tilsen-Mallett N, Rosen HR, Samojlik E, Veldhuis JD. Aminoglutethimide as an aromatase inhibitor: in vivo and in vitro pharmacologic studies. Cancer Research 1982; 42(8 Suppl):3353s-9s.
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780. Veldhuis JD, Sweinberg SK, Klase PA, Hammond JM. Dissociated regulation of cellular progesterone secretion and cytosolic ornithine decarboxylase activity in isolated ovarian cells in vitro. Endocrinology 1981 Nov; 109(5):1657-62.
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781. Veldhuis JD. Interactions among endocrine control systems in the regulation of ovarian function. Clin Biochem 1981 Oct; 14(5):252-7.
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782. Veldhuis JD, Melby JC. Isolated aldosterone deficiency in man: acquired and inborn errors in the biosynthesis or action of aldosterone. Endocr Rev 1981 Fall; 2(4):495-517.
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783. Veldhuis JD, Klase PA, Hammond JM. Direct actions of 17 beta-estradiol on progesterone production by highly differentiated porcine granulosa cells in vitro. II. Regulatory interactions of estradiol with luteinizing hormone and cyclic nucleotides. Endocrinology 1981 Aug; 109(2):433-42.
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784. Veldhuis JD, Sweinberg S. Multihormonal regulation of ornithine decarboxylase activity in highly differentiated porcine granulosa cells in vitro. J Cell Physiol 1981 Aug; 108(2):213-20.
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785. Veldhuis JD, Hammond JM. Role of calcium in the modulation of ornithine decarboxylase activity in isolated pig granulosa cells in vitro. Biochem J 1981 Jun 15; 196(3):795-801.
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786. Veldhuis JD, Klase PA, Hammond JM. Sex steroids modulate prolactin action in spontaneously luteinizing porcine granulosa cells in vitro. Endocrinology 1981 Apr; 108(4):1463-8.
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787. Veldhuis JD, Worgul TJ, Monsaert R, Hammond JM. A possible role of endogenous opioids in the control of prolactin and luteinizing-hormone secretion in the human. J Endocrinol Invest 1981 Jan-Mar; 4(1):31-6.
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788. Santen RJ, Veldhuis JD, Harvey HA, Lipton A. Chemotherapy and tamoxifen for breast cancer. New England Journal of Medicine 1981; 305:1014.
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789. Veldhuis JD, Hammond JM. Endocrine function after spontaneous infarction of the human pituitary: report, review, and reappraisal. Endocr Rev 1980 Winter; 1(1):100-7.
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790. Veldhuis JD, Kulin HE, Santen RJ, Wilson TE, Melby JC. Inborn error in the terminal step of aldosterone biosynthesis. Corticosterone methyl oxidase tpe II deficiency in a North American pedigree. N Engl J Med 1980 Jul 17; 303(3):117-21.
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791. Veldhuis JD, Klase P, Hammond JM. Divergent effects of prolactin upon steroidogenesis by porcine granulosa cells in vitro: influence of cytodifferentiation. Endocrinology 1980 Jul; 107(1):42-6.
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792. Veldhuis JD, Hammond JM. Oestrogens regulate divergent effects of prolactin in the ovary. Nature 1980 Mar 20; 284(5753):262-4.
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793. Samojlik E, Veldhuis JD, Wells SA, Santen RJ. Preservation of androgen secretion during estrogen suppression with aminoglutethimide in the treatment of metastatic breast carcinoma. J Clin Invest 1980 Mar; 65(3):602-12.
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794. Veldhuis JD, Harrison TS, Hammond JM. Beta-2-Adrenergic stimulation of ornithine decarboxylase activity in porcine granulosa cells in vitro. Biochim Biophys Acta 1980 Jan 17; 627(2):123-30.
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795. Demers LM, Veldhuis JD, Ramos E. The clinical entity of pseudo-Bartter's syndrome. Advances in Prostaglandin & Thromboxane Research 1980; 7:1203-6.
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796. Veldhuis JD, Hammond JM. Role of ornithine decarboxylase in granulosa-cell replication and steroidogenesis in vitro. Biochem Biophys Res Commun 1979 Dec 14; 91(3):770-7.
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797. Veldhuis JD, Green JE 3rd, Kovacs E, Worgul TJ, Murray FT, Hammond JM. Prolactin-secreting pituitary adenomas. Association with multiple endocrine neoplasia, type I. Am J Med 1979 Nov; 67(5):830-7.
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798. Veldhuis JD, Santen RJ. Pituitary pseudotumor. Mimicry of recurrent prolactinoma by a chronic intrasellar hematoma. Arch Intern Med 1979 Nov; 139(11):1309-11.
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799. Veldhuis JD, Demers LM, Hammond JM. Regulation of ornithine decarboxylase in isolated granulosa cells in vitro by constituents of follicular fluid. Endocrinology 1979 Nov; 105(5):1143-51.
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800. Veldhuis JD, Kulin HE, Demers LM, Lambert PW. Infantile hypercalcemia with subcutaneous fat necrosis: endocrine studies. J Pediatr 1979 Sep; 95(3):460-2.
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801. Veldhuis JD, Bardin CW, Demers LM. Metabolic mimicry of Bartter's syndrome by covert vomiting: utility of urinary chloride determinations. Am J Med 1979 Feb; 66(2):361-3.
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802. Veldhuis JD, Hammond JM. Multiplication stimulating activity regulates ornithine decarboxylase in isolated porcine granulosa cells in vitro. Endocr Res Commun 1979; 6(4):299-309.
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803. Veldhuis JD, Santen RJ. Hypopituitarism. Current Therapy 1979; 31:460-4.
804. Santen RJ, Santner S, Davis B, Veldhuis J, Samojlik E, Ruby E. Aminoglutethimide inhibits extraglandular estrogen production in postmenopausal women with breast carcinoma. J Clin Endocrinol Metab 1978 Dec; 47(6):1257-65.
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