Publications - John M . Miles, M.D.

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1. Hudson SB, Schroeder DR, Bailey JN, Mielke KL, Erickson D, Miles JM, Bowers CY, Veldhuis JD. Pre- Versus Postmenopausal Age, Estradiol, and Peptide-Secretagogue Type Determine Pulsatile Growth Hormone Secretion in Healthy Women: Studies Using Submaximal Agonist Drive and an Estrogen Clamp. J Clin Endocrinol Metab 2009 Oct 26. [Epub ahead of print]
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2. Veldhuis JD, Keenan DM, Bailey JN, Miles JM, Bowers CY. Preservation of GHRH and GH-releasing peptide-2 efficacy in young men with experimentally induced hypogonadism. Eur J Endocrinol 2009 Aug; 161(2):293-300. Epub 2009 May 20.
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3. Kitabchi AE, Umpierrez GE, Miles JM, Fisher JN. Hyperglycemic crises in adult patients with diabetes [Turkish]. Diabetes Care 2009 Jul; 32(7):1335-43.
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4. Veldhuis JD, Keenan DM, Bailey JN, Adeniji AM, Miles JM, Bowers CY. Novel relationships of age, visceral adiposity, insulin-like growth factor (IGF)-I and IGF binding protein concentrations to growth hormone (GH) releasing-hormone and GH releasing-peptide efficacies in men during experimental hypogonadal clamp. J Clin Endocrinol Metab 2009 Jun; 94(6):2137-43. Epub 2009 Apr 07.
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5. Veldhuis JD, Mielke KL, Cosma M, Soares-Welch C, Paulo R, Miles JM, Bowers CY. Aromatase and 5alpha-reductase inhibition during an exogenous testosterone clamp unveils selective sex steroid modulation of somatostatin and growth hormone secretagogue actions in healthy older men. J Clin Endocrinol Metab 2009 Mar; 94(3):973-81. Epub 2008 Dec 16.
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6. Veldhuis JD, Keenan DM, Bailey JN, Adeniji A, Miles JM, Paulo R, Cosma M, Soares-Welch C. Testosterone supplementation in older men restrains insulin-like growth factor's dose-dependent feedback inhibition of pulsatile growth hormone secretion. J Clin Endocrinol Metab 2009 Jan; 94(1):246-54. Epub 2008 Nov 04.
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7. Harris WS, Isley WL, Miles JM. Combined therapy with omega-3 fatty acids and niacin in atherogenic dyslipidemia. Submitted for publication 2009.
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8. Veldhuis JD, Keenan DM, Bailey JN, Adeniji A, Miles JM, Paulo R, Cosma M, Soares-Welch C. Estradiol supplementation in postmenopausal women attenuates suppression of pulsatile growth hormone secretion by recombinant human insulin-like growth factor type I. J Clin Endocrinol Metab 2008 Nov; 93(11):4471-8. Epub 2008 Aug 26.
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9. Kok P, Paulo RC, Cosma M, Mielke KL, Miles JM, Bowers CY, Veldhuis JD. Estrogen supplementation selectively enhances hypothalamo-pituitary sensitivity to ghrelin in postmenopausal women. J Clin Endocrinol Metab 2008 Oct; 93(10):4020-6. Epub 2008 Jul 08.
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10. Sheikh-Ali M, Karon BS, Basu A, Kudva YC, Muller LA, Xu J, Schwenk WF, Miles JM. Can serum beta-hydroxybutyrate be used to diagnose diabetic ketoacidosis? Diabetes Care 2008 Apr; 31(4):643-7. Epub 2008 Jan 09.
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11. Cosma M, Bailey J, Miles JM, Bowers CY, Veldhuis JD. Pituitary and/or peripheral estrogen-receptor alpha regulates follicle-stimulating hormone secretion, whereas central estrogenic pathways direct growth hormone and prolactin secretion in postmenopausal women. J Clin Endocrinol Metab 2008 Mar; 93(3):951-8. Epub 2007 Dec 18.
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12. Paulo RC, Cosma M, Soares-Welch C, Bailey JN, Mielke KL, Miles JM, Bowers CY, Veldhuis JD. Gonadal status and body mass index jointly determine growth hormone (GH)-releasing hormone/GH-releasing peptide synergy in healthy men. J Clin Endocrinol Metab 2008 Mar; 93(3):944-50. Epub 2007 Dec 11.
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13. Miles JM, McMahon MM, Isley WL. For Debate: No, the glycaemic target in the critically ill should not be ≤ 6.1 mmol/1 Diabetologia 2008; 51:916-20.
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14. Nelson RH, Basu R, Johnson CM, Rizza RA, Miles JM. Splanchnic spillover of extracellular lipase-generated fatty acids in overweight and obese humans. Diabetes 2007 Dec; 56(12):2878-84. Epub 2007 Sep 19.
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15. Miles JM, Nelson RH. Contribution of triglyceride-rich lipoproteins to plasma free fatty acids. Horm Metab Res 2007 Oct; 39(10):726-9.
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16. Nelson RH, Edgerton DS, Basu R, Roesner JC, Cherrington AD, Miles JM. Triglyceride uptake and lipoprotein lipase-generated fatty acid spillover in the splanchnic bed of dogs. Diabetes 2007 Jul; 56(7):1850-5. Epub 2007 Apr 06.
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17. Nelson RH, Prasad A, Lerman A, Miles JM. Myocardial uptake of circulating triglycerides in nondiabetic patients with heart disease. Diabetes 2007 Feb; 56(2):527-30.
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18. Isley WL, Miles JM, Harris WS. Combined therapy with n-3 fatty acids and niacin in atherogenic dyslipidemia. J Clin Lipidol 2007; 1:211-17.
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19. Veldhuis JD, Keenan DM, Iranmanesh A, Mielke K, Miles JM, Bowers CY. Estradiol potentiates ghrelin-stimulated pulsatile growth hormone secretion in postmenopausal women. J Clin Endocrinol Metab 2006 Sep; 91(9):3559-65. Epub 2006 Jun 27.
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20. Veldhuis JD, Iranmanesh A, Mielke K, Miles JM, Carpenter PC, Bowers CY. Ghrelin potentiates growth hormone secretion driven by putative somatostatin withdrawal and resists inhibition by human corticotropin-releasing hormone. J Clin Endocrinol Metab 2006 Jun; 91(6):2441-6.
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21. Isley WL, Harris WS, Miles JM. The effect of high-dose simvastatin on free fatty acid metabolism in patients with type 2 diabetes mellitus. Metabolism 2006 Jun; 55(6):758-62.
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22. Veldhuis JD, Iranmanesh A, Mielke K, Miles JM, Carpenter PC, Bowers CY. Ghrelin potentiates growth hormone secretion driven by putative somatostatin withdrawal and resists inhibition by human corticotropin-releasing hormone. J Clin Endocrinol Metab 2006 Jun; 91(6):2441-6. Epub 2006 Mar 14.
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23. Miles JM. Energy expenditure in hospitalized patients: implications for nutritional support. Mayo Clin Proc 2006 Jun; 81(6):809-16.
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24. McMahon MM, Miles JM. Glycemic control and nutrition in the intensive care unit. Curr Opin Clin Nutr Metab Care 2006 Mar; 9(2):120-3.
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25. Isley WL, Miles JM, Patterson BW, Harris WS. The effect of high-dose simvastatin on triglyceride-rich lipoprotein metabolism in patients with type 2 diabetes mellitus. J Lipid Res 2006 Jan; 47(1):193-200. Epub 2005 Oct 28.
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26. Nelson RH, Miles JM. Use of orlistat in obese, dyslipidemic patients. Future Lipidology 2006; 1:267-75.
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27. Veldhuis JD, Erickson D, Iranmanesh A, Miles JM, Bowers CY. Sex-steroid control of the aging somatotropic axis. Endocrinology & Metabolism Clinics of North America 2005 Dec; 34(4):877-93.
28. Nelson RH, Miles JM. The use of orlistat in the treatment of obesity, dyslipidaemia and Type 2 diabetes. Expert Opin Pharmacother 2005 Nov; 6(14):2483-91.
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29. Veldhuis JD, Keenan DM, Mielke K, Miles JM, Bowers CY. Testosterone supplementation in healthy older men drives GH and IGF-I secretion without potentiating peptidyl secretagogue efficacy. European Journal of Endocrinology 2005 Oct; 153(4):577-86.
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30. Coppack SW, Chinkes DL, Miles JM, Patterson BW, Klein S. A multicompartmental model of in vivo adipose tissue glycerol kinetics and capillary permeability in lean and obese humans. Diabetes 2005 Jul; 54(7):1934-41.
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31. Soares-Welch C, Farhy L, Mielke KL, Mahmud FH, Miles JM, Bowers CY, Veldhuis JD. Complementary secretagogue pairs unmask prominent gender-related contrasts in mechanisms of growth hormone pulse renewal in young adults. J Clin Endocrinol Metab 2005 Apr; 90(4):2225-32. Epub 2005 Jan 05.
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32. Miles JM, Jensen MD. The role of visceral fat in the pathogenesis of insulin resistance: marker or mediator? Diabetes Care 2005; 28:2326-28.
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33. Erickson D, Keenan DM, Mielke K, Bradford K, Bowers CY, Miles JM, Veldhuis JD. Dual secretagogue drive of burst-like growth hormone secretion in postmenopausal compared with premenopausal women studied under an experimental estradiol clamp. J Clin Endocrinol Metab 2004 Sep; 89(9):4746-54.
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34. Choong NWW, Miles JM. Bilateral carotid body paraganglioma. Mayo Clin Proc 2004 May; 79(5):681.
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35. Miles JM, Park YS, Walewicz D, Russell-Lopez C, Windsor S, Isley WL, Coppack SW, Harris WS. Systemic and forearm triglyceride metabolism - Fate of lipoprotein lipase-generated glycerol and free fatty acids. Diabetes 2004 Mar; 53(3):521-7.
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36. Miles JM. Insulin in the early management of diabetic complications. J Assoc Physicians India 2003 May; 51:501-5.
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37. Miles JM, Wooldridge D, Grellner WJ, Windsor S, Isley WL, Klein S, Harris WS. Nocturnal and postprandial free fatty acid kinetics in normal and type 2 diabetic subjects-effects of insulin sensitization therapy. Diabetes 2003 Mar; 52(3):675-81.
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38. Martindale R, Miles J. Is immunonutrition ready for prime time? Two points of view. Nutr Clin Prac 2003; 18:489-496.
39. Mittendorfer B, Liem O, Patterson BW, Miles JM, Klein S. What does the measurement of whole body fatty acid rate of appearance in plasma by using a fatty acid tracer really mean? Diabetes 2003; 52:1641-1648.
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40. Miles JM, Leiter L, Hollander P, Wadden T, Anderson JW, Doyle M, Foreyt J, Aronne L, Klein S. Effect of orlistat in overweight and obese patients with type 2 diabetes treated with metformin. Diabetes Care 2002 Jul; 25(7):1123-8.
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41. Patel JN, Coppack SW, Goldstein DS, Miles JM, Eisenhofer G. Norepinephrine spillover from human adipose tissue before and after a 72-hour fast. J Clin Endocrinol Metab 2002 Jul; 87(7):3373-7.
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42. Kelley DE, Pi-Sunyer FX, Hollander P, Klein S, Miles J, Wing R, Bray GA. A One-Year, Randomized, Double-Blind Study of Orlistat in Obese Insulin-Treated Patients with Type 2 Diabetes Mellitus. Diabetes Care 2002; 25:1033-41.
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43. Miles JM, Park Y, Harris WS. Lipoprotein lipase and triglyceride-rich lipoprotein metabolism. Nutr Clin Prac 2001; 16:273-9.
44. Park Y, Damron B, Miles JM, Harris WS. Measurement of human chylomicron triglyceride clearance with a labelled commercial lipid emulsion. Lipids 2001; 36:115-20.
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45. Patel J, Coppack SW, Rawesh A, Miles JM, Eisenhofer G. Regional and total body changes in sympathoadrenal activity in response to eating. Int J Obesity 2000; 2(24 Suppl):S156-7.
46. Park Y, Grellner WJ, Harris WS, Miles JM. A new method for the study of chylomicron kinetics in vivo. Am J Physiol 2000; 279:E1258-63.
47. Coppack SW, Persson M, Judd R, Miles JM. Glycerol and nonesterified fatty acid metabolism in human muscle and adipose tissue in vivo. Am J Physiol 1999; 39:E233-40.
48. Goldstein DS, Swoboda KJ, Miles JM, Coppack SW, Aneman A, Holmes C, Lamensdorf I, Eisenhofer G. Sources and physiological significance of plasma dopamine sulfate. J Clin Endo Metab 1999; 84:2523-31.
49. Patel JN, Eisenhofer G, Coppack SW, Miles JM. Norepinephrine spillover in forearm and subcutaneous adipose tissue before and after eating. J Clin Endo Metab 1999; 84:2815-9.
50. O'Keefe Jr JH, Miles JM, Harris WH, Moe RM, McCallister BD. Improving the adverse cardiovascular prognosis of Type 2 Diabetes. Mayo Clin Proc 1999; 74:171-80.
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51. Judd RL, Nelson R, Klein S, Jensen MD, Miles JM. Measurement of plasma glycerol specific activity by high performance liquid chromatography to determine glycerol flux. J Lipid Res 1998 May; 39(5):1106-10.
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52. Fisher RM, Miles JM, Kottke BA, Frayn KN, Coppack SW. Very-low-density lipoprotein subfraction composition and metabolism by adipose tissue. Metabolism: Clinical & Experimental 1997 Jun; 46(6):605-10.
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53. Divertie GD, Jensen MD, Cryer PE, Miles JM. Lipolytic responsiveness to epinephrine in nondiabetic and diabetic humans. Am J Physiol 1997 Jun; 272(6 Pt 1):E1130-5.
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54. Zhang T, Murray M, Klocke K, Miles JM, Holman RT. Effects of the incubation of long-chain polyunsaturated fatty acids on platelet lipids and thromboxane release. Prostaglandins Leukotrienes & Essential Fatty Acids 1997 Apr; 56(4):259-64.
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55. Mohamed-Ali V, Goodrick S, Rawesh A, Miles JM, Katz D, Yudkin JS, Coppack SW. Subcutaneous adipose tissue secretes interleukin-6 but not tumour necrosis factor-alpha in vitro. J Clin Endo Metab 1997; 82:4196-200.
56. Cersosimo E, Danou F, Persson M, Miles JM. Effect of pulsatile growth hormone secretion on adipose tissue lipolysis in humans. Am J Physiol 1996; 271:E123-6.
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57. Miles JM. Should protein be included or excluded from calorie counts? Nutr Clin Prac 1996; 11:204-6.
58. Klein S, Miles J. Substrate metabolism in humans. JPEN 1996; 20:13-9.
59. Coppack SW, Yost TJ, Fisher RM, Eckel RH, Miles JM. Periprandial systemic and regional lipase activity in normal man. Am J Physiol 1996; 270:E718-22.
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60. Coppack SW, Persson M, Miles JM. Phenylalanine kinetics in human adipose tissue. J Clin Invest 1996; 98:692-7.
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61. Dinneen S, Alzaid A, Miles J, Rizza R. Effects of the normal nocturnal rise in cortisol on carbohydrate and fat metabolism in IDDM. Am J Physiol 1995 Apr; 268(4 Pt 1):E595-603.
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62. O'Keefe JH, Nguyen T, Nelson J, O'Keefe L, Miles J. Potential beneficial effects of monounsaturated and polyunsaturated fats in elderly patients with or at risk of coronary artery disease. Cardiology in the Elderly 1995 Feb; 3:5-10.
63. Kinsey GC, Murray MJ, Swensen SJ, Miles JM. Glucose content of tracheal aspirates: implications for the detection of tube feeding aspiration. Crit Care Med 1994 Oct; 22(10):1557-62.
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64. Cersosimo E, Judd RL, Miles JM. Insulin regulation of renal glucose metabolism in conscious dogs. J Clin Invest 1994 Jun; 93(6):2584-9.
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65. Coppack SW, Jensen MD, Miles JM. In vivo regulation of lipolysis in humans. J Lipid Res 1994 Feb; 35(2):177-93.
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66. Lynch JW, Miles JM, Bailey JW. Effects of the short-chain triglyceride, triacetin on intestinal mucosa and metabolic substrates in rats. JPEN 1994; 18:208-13.
67. Miles JM. Energy requirements in nutrition support: quantitative and qualitative considerations. Frontiers Clin Nutr 1994; 3:9-12.
68. Miles JM. Techniques for the measurement of ketone body and lactate kinetics in vivo. Diabetes Reviews 1994; 2:239-48.
69. Klein S, Miles JM. Metabolic Effects of Long-Chain and Medium-Chain Triglyceride Emulsions in Humans. JPEN 1994; 18:396-7.
70. Bleiberg B, Beers TR, Persson M, Miles JM. Metabolism of triacetin-derived acetate in dogs. Am J Clin Nutr 1993 Dec; 58:908-911.
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71. Bailey JW, Miles JM, Haymond MW. Effect of parenteral administration of short-chain triglycerides on leucine metabolism. Am J Clin Nutr 1993 Dec; 58:912-916.
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72. Dinneen S, Alzaid A, Miles J, Rizza R. Metabolic effects of the nocturnal rise in cortisol on carbohydrate metabolism in normal humans. J Clin Invest 1993 Nov; 92(5):2283-90.
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73. Hamel N, Divertie G, Silverberg J, Persson M, Miles J. Tracer disequilibrium in CO2 compartments during NaH14CO3 infusion. Metabolism: Clinical & Experimental 1993 Aug; 42(8):993-7.
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74. Fisher RM, Coppack SW, Kottke BA, Miles JM. Very low density lipoprotein subfraction apolipoprotein composition. Biochem Soc Trans 1993 Aug; 21 ( Pt 3)(3):231S.
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75. Miles JM. Lipid fuel metabolism in health and disease. Curr Opin Gen Surg 1993; 1:78-84.
76. Elahi D, McAloon-Dyke M, Fukagawa N, Sclater A, Wong G, Shannon RP, Minaker K, Miles J, Rubenstein A, Vandepol C, Guler H-P, Good W, Seaman J, Wolfe R. The effects of human recombinant IGF-I on glucose and leucine kinetics in man. Am J Physiol 1993; 256:E831-838.
77. Fisher RM, Coppack SW, Kottke BA, Miles JM. Very low density lipoprotein subfraction apolipoprotein composition. Biochem Soc Trans 1993; 21:231S.
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78. McMahon M, Miles JM. Common errors in enteral and parenteral nutrition support. Seminars in Gastrointestinal Disease 1993; 4:127-36.
79. Miles JM. Pearls of diabetic management. The Practice of Internal Medicine-1992 1992 May 11-15; 97-100.
80. Bleiberg B, Beers TR, Persson M, Miles JM. Systemic and regional acetate kinetics in the dog. Am J Physiol 1992; 262:E197-202.
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81. Heiling VJ, Miles JM, Jensen MD. How valid are isotopic measurements of fatty acid oxidation? Am J Physiol 1991 Nov; 261(PART 1 OF 2 PARTS):E572-E577.
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82. Persson M, Bleiberg B, Kiss D, Miles JM. Measurement of plasma acetate kinetics using high-performance liquid chromatography. Anal Biochem 1991 Oct; 198:149-153.
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83. Bailey JW, Jensen MD, Miles JM. Effects of intravenous methyl palmoxirate on the turnover and oxidation of fatty acids in conscious dogs. Metabolism: Clinical & Experimental 1991 Apr; 40(4):428-31.
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84. Jensen MD, Heiling VJ, Miles JM. Effects of glucagon on free fatty acid metabolism in humans. J Clin Endocrinol Metab 1991 Feb; 72(2):308-15.
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85. Miles JM, Cattalini M, Sharbrough FW, Wold LE, Wharen RE Jr, Gerich JE, Haymond MW. Metabolic and neurologic effects of an intravenous medium-chain triglyceride emulsion. JPEN: Journal of Parenteral & Enteral Nutrition 1991 Jan-Feb; 15(1):37-41.
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86. Divertie GD, Jensen MD, Miles J. Stimulation of lipolysis in humans by physiological hypercortisolemia. Diabetes 1991; 40:1228-1232.
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87. Bailey JW, Haymond MW, Miles JM. Triacetin: A potential parenteral nutrient. JPEN 1991; 15:32-6.
88. Keller U, Miles JM. Growth hormone and lipids. Horm Res 36 ( 1991; Suppl. 1):36-40.
89. Miles JM. Intravenous fat emulsions in nutritional support. Curr Opin Gastroenterol 1991; 7(2):306-11.
90. Bailey JW, Haymond MW, Miles JM. Metabolism of ketone bodies by skeletal muscle in starvation and uncontrolled diabetes. Metabolism 1990 Oct; 39:1039-1043.
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91. Caruso M, Divertie GD, Jensen MD, Miles JM. Lack of effect of hyperglycemia on lipolysis in humans. Am J Physiol 1990 Oct; 259(4 Pt 1):E542-7.
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92. Bailey JW, Haymond MW, Miles JM. Validation of two-pool model for in vivo ketone body kinetics. Am J Physiol 1990 May; 258(PART 1):E850-E855.
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93. Ruegemer JJ, Squires RW, Marsh HM, Haymond MW, Cryer PE, Rizza RA, Miles JM. Differences between prebreakfast and late afternoon glycemic responses to exercise in IDDM patients. Diabetes Care 1990 Feb; 13(2):104-10.
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94. Jensen MD, Heiling V, Miles JM. Measurement of non-steady-state free fatty acid turnover. Am J Physiol 1990 Jan; 258(1 Pt 1):E103-8.
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95. Haymond MW, Tessari P, Beaufrere B, Rodriguez N, Bailey J, Miles JM. Fatty acid chain length affects leucine metabolism during parenteral infusions of triglycerides. Int Congr Ser 1990; 872:333-338.
96. Horber FF, Krayer S, Miles J, Cryer P, Rehder K, Haymond MW. Isoflurane and whole body leucine, glucose and fatty acid metabolism in dogs. Anesthesiology 1990; 73:82-92.
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97. Jensen MD, Caruso M, Heiling V, Miles JM. Insulin regulation of lipolysis in nondiabetic and IDDM subjects. Diabetes 1989 Dec; 38(12):1595-601.
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98. Rodriguez NR, Miles JM, Schwenk WF, Haymond MW. Effects of acute metabolic acidosis and alkalosis on leucine metabolism in conscious dogs. Diabetes 1989 Jul; 38(7):847-53.
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99. Bowyer BA, Fleming CR, Haymond MW, Miles JM. L-carnitine: effect of intravenous administration on fuel homeostases in normal subjects and home-parenteral-nutrition patients with low plasma carnitine concentrations. Am J Clin Nutr 1989 Apr; 49:618-623.
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100. Jensen MD, Haymond MW, Rizza RA, Cryer PE, Miles JM. Influence of body fat distribution on free fatty acid metabolism in obesity. J Clin Invest 1989 Apr; 83(4):1168-73.
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101. Bailey JW, Heath H III, Miles JM. Calcium, magnesium, and phosphorus metabolism in dogs given intravenous triacetin. Am J Clin Nutr 1989 Feb; 49:385-388.
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102. Brandt KR, Miles JM. Relationship between severity of hyperglycemia and metabolic acidosis in diabetic ketoacidosis. Mayo Clin Proc 1988 Nov; 63(11):1071-4.
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103. Haymond MW, Tessari P, Beaufrere B, Rodriguez N, Bailey J, Miles JM. Effects of parenteral lipid on leucine metabolism: dependence of fatty acid chain length. JPEN J Parenter Enteral Nutr 1988 Nov-Dec; 12(Suppl):94S-97S.
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104. Hoeltge GA, Dewald G, Miles J, Palmer C. Proficiency testing in clinical cytogenetics. The 1986 experience of the College of American Pathologists. Archives of Pathology & Laboratory Medicine 1988 Nov; 112(11):1085-90.
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105. Jensen MD, Miles JM, Gerich JE, Cryer PE, Haymond MW. Preservation of insulin effects on glucose production and proteolysis during fasting. Am J Physiol 1988 Jun; 254(PART 1):E707-E707.
106. Jensen MD, Rogers PJ, Ellman MG, Miles JM. Choice of infusion-sampling mode for tracer studies of free fatty acid metabolism. Am J Physiol 1988 May; 254(5 Pt 1):E562-5.
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107. Nurjhan N, Kennedy F, Consoli A, Martin C, Miles J, Gerich J. Quantification of the glycolytic origin of plasma glycerol: implications for the use of the rate of appearance of plasma glycerol as an index of lipolysis in vivo. Metabolism: Clinical & Experimental 1988 Apr; 37(4):386-9.
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108. Bowyer BA, Miles JM, Haymond MW, Fleming CR. L-carnitine therapy in home parenteral nutrition patients with abnormal liver tests and low plasma carnitine concentrations. Gastroenterology 1988 Feb; 94(2):434-8.
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109. Consoli A, Kennedy F, Miles JM, Gerich JE. Determination of Krebs cycle metabolic carbon exchange in vivo and its use to estimate the individual contributions of gluconeogenesis and glycogenolysis to overall glucose output in man. J Clin Invest 1987 Nov; 80:1303-1310.
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110. Kennedy FP, Miles JM, Heiling V, Gerich JE. The effect of two new alpha-glucosidase inhibitors on metabolic responses to a mixed meal in normal volunteers. Clin Exp Pharmacol Physiol 1987 Aug; 14(8):633-40.
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111. Caruso M, Orszulak TA, Miles JM. Lactic acidosis and insulin resistance associated with epinephrine administration in a patient with non-insulin-dependent diabetes mellitus. Arch Intern Med 1987 Aug; 147(8):1422-4.
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112. Miles JM, Ellman MG, McClean KL, Jensen MD. Validation of a new method for determination of free fatty acid turnover. Am J Physiol 1987 Mar; 252(3 Pt 1):E431-8.
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113. Jensen MD, Haymond MW, Gerich JE, Cryer PE, Miles JM. Lipolysis during fasting. Decreased suppression by insulin and increased stimulation by epinephrine. J Clin Invest 1987 Jan; 79(1):207-13.
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114. Nurjhan N, Campbell PJ, Kennedy FP, Miles JM, Gerich JE. Insulin dose-response characteristics for suppression of glycerol release and conversion to glucose in humans. Diabetes 1986 Dec; 35(12):1326-31.
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115. Jensen MD, Miles JM. The roles of diet and exercise in the management of patients with insulin-dependent diabetes mellitus. Mayo Clin Proc 1986 Oct; 61(10):813-9.
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116. Miles JM, Jensen MD. Complications of insulin-dependent diabetes mellitus: management of insulin reactions and acute illness. Mayo Clin Proc 1986 Oct; 61(10):820-4.
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117. Rodriguez N, Schwenk WF, Beaufrere B, Miles JM, Haymond MW. Trioctanoin infusion increases in vivo leucine oxidation: a lesson in isotope modeling. Am J Physiol 1986 Sep; 251(3 Pt 1):E343-8.
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118. Miles JM, Schwenk WF, McClean KL, Haymond MW. A dual-isotope technique for determination of in vivo ketone body kinetics. Am J Physiol 1986 Aug; 251(2 Pt 1):E185-91.
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119. Tessari P, Nissen SL, Miles JM, Haymond MW. Inverse relationship of leucine flux and oxidation to free fatty acid availability in vivo. J Clin Invest 1986 Feb; 77:575-581.
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120. Miles JM. Isotope dilution techniques for the study of in vivo ketone body metabolism. Int Congr Ser 1986; 70:362-366.
121. Schwenk WF, Miles JM, Triebwasser K, Gerich JE, Haymond MW. Importance of gluconeogenesis during meal absorption. Clin Res 1985 Oct; 33:852A.
122. Beaufrere B, Tessari P, Cattalini M, Miles JM, Haymond MW. Apparent decreased oxidation and turnover of leucine during infusion of medium-chain triglycerides. Am J Physiol 1985 Aug; 249(PART 1):E175-A182.
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123. Schwenk WF, Berg PJ, Beaufrere B, Miles JM, Haymond MW. Use of t-butyldimethylsilylation in the gas chromatographic/mass spectrometric analysis of physiologic compounds found in plasma using electron-impact ionization. Anal Biochem 1984 Aug 15; 141(1):101-9.
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124. Miles JM, Schwenk WF, McClean KL, Haymond MW. Determination of ketone body turnover in vivo with stable isotopes, utilizing gas chromatography/mass spectrometry. Anal Biochem 1984 Aug 15; 141(1):110-5.
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125. Miles JM, Nissen SL, Gerich JE, Haymond MW. Effects of epinephrine infusion on leucine and alanine kinetics in humans. Am J Physiol 1984 Aug; 247(PART 1):E166-E172.
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126. Simmons PS, Miles JM, Gerich JE, Haymond MW. Increased proteolysis. An effect of increases in plasma cortisol within the physiologic range. J Clin Invest 1984 Feb; 73(2):412-20.
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127. Miles JM. The Pathogenesis of Non-Insulin Dependent Diabetes. Transition 1984; 2:11-5.
128. Miles JM, Haymond MW, Nissen SL, Gerich JE. Effects of free fatty acid availability, glucagon excess, and insulin deficiency on ketone body production in postabsorptive man. J Clin Invest 1983 Jun; 71:1554-1561.
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129. Kelly JJ Jr, Kyle RA, Miles JM, Dyck PJ. Osteosclerotic myeloma and peripheral neuropathy. Neurology 1983 Feb; 33(2):202-10.
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130. Miles J, Nissen S, Rizza RA, Gerich J, Haymond M. Failure of infused beta-hydroxybutyrate to decrease proteolysis in man. Diabetes 1983; 32:197-205.
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131. Miles JM, Glasscock R, Aikens J, Gerich JE, Haymond MW. A microfluorometric method for the determination of free fatty acids in plasma. J Lipid Res 1983; 24:96-99.
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132. Miles JM, Gerich JE. Glucose and ketone body kinetics in diabetic ketoacidosis. Clin Endocrinol Metab 1983; 12:303-319.
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133. Nissen SL, Miles JM, Gerich JE, Haymond MW. Regulation of alpha-ketoisocaproate binding to albumin in vivo by free fatty acids. Am J Physiol 1982 Jan; 242:E67-E71.
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134. Haymond MW, Miles JM. Branched chain amino acids as a major source of alanine nitrogen in man. Diabetes 1982 Jan; 31:86-89.
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135. Rizza RA, Haymond MW, Verdonk CA, Mandarino LJ, Miles JM, Service FJ, Gerich JE. Pathogenesis of hypoglycemia in insulinoma patients: suppression of hepatic glucose production by insulin. Diabetes 1981 May; 30(5):377-81.
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136. Kelly JJ Jr, Kyle RA, Miles JM, O'Brien PC, Dyck PJ. The spectrum of peripheral neuropathy in myeloma. Neurology 1981 Jan; 31(1):24-31.
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137. Miles JM, Haymond MW, Gerich JE. Suppression of glucose production and stimulation of insulin secretion by physiological concentrations of ketone bodies in man. J Clin Endocrinol Metab 1981 Jan; 52:34-37.
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