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Publications - Claudia F . Lucchinetti, M.D.

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  1. Kale N, Pittock SJ, Lennon VA, Thomsen K, Roemer S, McKeon A, Lucchinetti CF. Humoral Pattern II Multiple Sclerosis Pathology Not Associated With Neuromyelitis Optica IgG. Arch Neurol 2009 Oct; 66(10):1298-9.
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  2. Hu W, Lucchinetti CF. The pathological spectrum of CNS inflammatory demyelinating diseases. Semin Immunopathol 2009 Sep 25. [Epub ahead of print]
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  3. Jacob A, Matiello M, Weinshenker BG, Wingerchuk DM, Lucchinetti C, Shuster E, Carter J, Keegan BM, Kantarci OH, Pittock SJ. Treatment of neuromyelitis optica with mycophenolate mofetil: retrospective analysis of 24 patients. Arch Neurol 2009 Sep; 66(9):1128-33.
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  4. Staff NP, Lucchinetti CF, Keegan BM. Multiple Sclerosis with predominant, severe cognitive impairment. Arch Neurol 2009 Sep; 66:1139-43.
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  5. McKeon A, Fryer JP, Apiwattanakul M, Lennon VA, Hinson SR, Kryzer TJ, Lucchinetti CF, Weinshenker BG, Wingerchuk DM, Shuster EA, Pittock SJ. Diagnosis of neuromyelitis spectrum disorders: comparative sensitivities and specificities of immunohistochemical and immunoprecipitation assays. Arch Neurol 2009 Sep; 66(9):1134-8.
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  6. Jacob A, Matiello M, Weinshenker BG, Wingerchuk DM, Lucchinetti C, Shuster E, Carter J, Keegan BM, Kantarci OH, Pittock SJ. Treatment of neuromyelitis optica with mycophenolate mofetil retrospective analysis of 24 patients. Arch Neurol 2009 Sep; 66(9):1128-33.
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  7. McKeon A, Fryer JP, Apiwattanakul M, Lennon VA, Hinson SR, Kryzer TJ, Lucchinetti CF, Weinshenker BG, Wingerchuk DM, Shuster EA, Pittock SJ. Diagnosis of neuromyelitis spectrum disorders comparative sensitivities and specificities of immunohistochemical and immunoprecipitation assays. Arch Neurol 2009 Sep; 66(9):1134-8.
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  8. Staff NP, Lucchinetti CF, Keegan BM. Multiple sclerosis with predominant, severe cognitive impairment. Arch Neurol 2009 Sep; 66(9):1139-43.
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  9. Staff NP, Lucchinetti CF, Keegan BM. Multiple sclerosis with predominant, severe cognitive impairment. Arch Neurol 2009 Sep; 66(9):1139-43.
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  10. Magana SM, Pittock SJ, Lennon VA, Keegan BM, Weinshenker BG, Lucchinetti CF. Neuromyelitis optica IgG serostatus in fulminant central nervous system inflammatory demyelinating disease. Arch Neurol 2009 Aug; 66(8):964-6.
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  11. Daniels TB, Pollock BE, Miller RC, Lucchinetti CF, Leavitt JA, Brown PD. Radiation-induced optic neuritis after pituitary adenoma radiosurgery in a patient with multiple sclerosis: case report. J Neurooncol 2009 Jun; 93(2):263-7. Epub 2008 Dec 20.
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  12. Daniels TB, Pollock BE, Miller RC, Lucchinetti CF, Leavitt JA, Brown PD. Radiation-induced optic neuritis after pituitary adenoma radiosurgery in a patient with multiple sclerosis: case report. J Neurooncol 2009 Jun; 93(2):263-7.
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  13. Frischer JM, Bramow S, Dal-Bianco A, Lucchinetti CF, Rauschka H, Schmidbauer M, Laursen H, Sorensen PS, Lassmann H. The relation between inflammation and neurodegeneration in multiple sclerosis brains. Brain 2009 May; 132(Part 5):1175-89.
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  14. Frischer JM, Bramow S, Dal-Bianco A, Lucchinetti CF, Rauschka H, Schmidbauer M, Laursen H, Sorensen PS, Lassmann H. The relation between inflammation and neurodegeneration in multiple sclerosis brains. Brain 2009 May; 132(Pt 5):1175-89. Epub 2009 Mar 31.
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  15. Magana SM, Matiello M, Pittock SJ, McKeon A, Lennon VA, Rabinstein AA, Shuster E, Kantarci OH, Lucchinetti CF, Weinshenker BG. Posterior reversible encephalopathy syndrome in neuromyelitis optica spectrum disorders. Neurology 2009 Feb 24; 72(8):712-7.
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  16. McKeon A, Lennon VA, Jacob A, Matiello M, Lucchinetti CF, Kale N, Chan KH, Weinshenker BG, Apiwattinakul M, Wingerchuk DM, Pittock SJ. Coexistence of myasthenia gravis and serological markers of neurological autoimmunity in neuromyelitis optica. Muscle Nerve 2009 Jan; 39(1):87-90.
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  17. Daniels TB, Pollock BE, Miller RC, Lucchinetti CF, Leavitt JA, Brown PD. Radiation-induced optic neuritis after pituitary adenoma radiosurgery in a patient with multiple sclerosis: Case report. J Neurooncol 2009; 93(2):263-7 Epub 2008 Dec.
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  18. Frischer JM, Bramow S, Dal-Bianco A, Lucchinetti CF, Rauschka H, Schmidbauer M, Laursen H, Sorensen PS, Lassmann H. The relation between inflammation and neurodegeneration in multiple sclerosis brains. Brain 2009; 132:1175-89 Epub 2009 Mar 31.
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  19. Quintana FJ, Farez MF, Viglietta V, Iglesias AH, Merbl Y, Izquierdo G, Lucas M, Basso AS, Khoury SJ, Lucchinetti CF, Cohen IR, Weiner HL. Antigen microarrays identify unique serum autoantibody signatures in clinical and pathologic subtypes of multiple sclerosis. Proc Natl Acad Sci U S A 2008 Dec 2; 105(48):18889-94. Epub 2008 Nov 21.
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  20. Hinson SR, Roemer SF, Lucchinetti CF, Fryer JP, Kryzer TJ, Chamberlain JL, Howe CL, Pittock SJ, Lennon VA. Aquaporin-4-binding autoantibodies in patients with neuromyelitis optica impair glutamate transport by down-regulating EAAT2. J Exp Med 2008 Oct 27; 205(11):2473-81. Epub 2008 Oct 06.
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  21. Rodriguez FJ, Gamez JD, Vrana JA, Theis JD, Giannini C, Scheithauer BW, Parisi JE, Lucchinetti CF, Pendlebury WW, Bergen HR 3rd, Dogan A. Immunoglobulin derived depositions in the nervous system: novel mass spectrometry application for protein characterization in formalin-fixed tissues. Lab Invest 2008 Oct; 88(10):1024-37. Epub 2008 Aug 18.
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  22. McKeon A, Lennon VA, Lotze T, Tenenbaum S, Ness JM, Rensel M, Kuntz NL, Fryer JP, Homburger H, Hunter J, Weinshenker BG, Krecke K, Lucchinetti CF, Pittock SJ. CNS aquaporin-4 autoimmunity in children. Neurology 2008 Jul 8; 71(2):93-100. Epub 2008 May 28.
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  23. Lucchinetti CF, Gavrilova RH, Metz I, Parisi JE, Scheithauer BW, Weigand S, Thomsen K, Mandrekar J, Altintas A, Erickson BJ, Konig F, Giannini C, Lassmann H, Linbo L, Pittock SJ, Bruck W. Clinical and radiographic spectrum of pathologically confirmed tumefactive multiple sclerosis. Brain 2008 Jul; 131(Pt 7):1759-75. Epub 2008 Jun 05.
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  24. Matiello M, Lennon VA, Jacob A, Pittock SJ, Lucchinetti CF, Wingerchuk DM, Weinshenker BG. NMO-IgG predicts the outcome of recurrent optic neuritis. Neurology 2008 Jun 3; 70(23):2197-200. Epub 2008 Apr 23.
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  25. Scarisbrick IA, Linbo R, Vandell AG, Keegan M, Blaber SI, Blaber M, Sneve D, Lucchinetti CF, Rodriguez M, Diamandis EP. Kallikreins are associated with secondary progressive multiple sclerosis and promote neurodegeneration. Biol Chem 2008 Jun; 389(6):739-45.
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  26. Porter AB, Giannini C, Kaufmann T, Lucchinetti CF, Wu W, Decker PA, Atkinson JL, O'Neill BP. Primary central nervous system lymphoma can be histologically diagnosed after previous corticosteroid use: a pilot study to determine whether corticosteroids prevent the diagnosis of primary central nervous system lymphoma. Ann Neurol 2008 May; 63(5):662-7.
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  27. Keegan BM, Giannini C, Parisi JE, Lucchinetti CF, Boeve BF, Josephs KA. Sporadic adult-onset leukoencephalopathy with neuroaxonal spheroids mimicking cerebral MS. Neurology 2008 Mar 25; 70(13 Pt 2):1128-33. Epub 2008 Feb 20.
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  28. Young NP, Weinshenker BG, Lucchinetti CF. Acute disseminated encephalomyelitis: current understanding and controversies. Semin Neurol 2008 Feb; 28(1):84-94.
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  29. Lucchinetti CF. Multiple sclerosis and the spectrum of CNS inflammatory demyelinating diseases. Semin Neurol 2008 Feb; 28(1):3-6.
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  30. Banwell B, Tenembaum S, Lennon VA, Ursell E, Kennedy J, Bar-Or A, Weinshenker BG, Lucchinetti CF, Pittock SJ. Neuromyelitis optica-IgG in childhood inflammatory demyelinating CNS disorders. Neurology 2008 Jan 29; 70(5):344-52. Epub 2007 Dec 19.
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  31. Pittock SJ, Lennon VA, de Seze J, Vermersch P, Homburger HA, Wingerchuk DM, Lucchinetti CF, Zephir H, Moder K, Weinshenker BG. Neuromyelitis optica and non organ-specific autoimmunity. Arch Neurol 2008 Jan; 65(1):78-83.
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  32. Quintana F, Mauricio F, Iglesias A, Merbl Y, Lucas M, Basso A, Khoury S, Lucchinetti CF, Weiner H. Antigen microarrays identify serum autoantibody signatures associated with different clinical forms and pathologic subtypes of multiple sclerosis. Proc Natl Acad Sci U S A. 2008; 105:18889-94 Epub 2008 Nov 21.
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  33. Lucchinetti C. Pathological heterogeneity of idiopathic central nervous system inflammatory demyelinating disorders. Curr Top Microbiol Immunol 2008; 318:19-43.
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  34. Hinson SR, Pittock SJ, Lucchinetti CF, Roemer SF, Fryer JP, Kryzer TJ, Lennon VA. Pathogenic potential of IgG binding to water channel extracellular domain in neuromyelitis optica. Neurology 2007 Dec 11; 69(24):2221-31. Epub 2007 Oct 10.
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  35. Wingerchuk DM, Lennon VA, Lucchinetti CF, Pittock S, Weinshenker BG. The spectrum of neuromyelitis optica. Lancet Neurology 2007 Sep; 6(9):805-15.
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  36. Jacob A, Matiello M, Wingerchuk DM, Lucchinetti CF, Pittock SJ, Weinshenker BG. Neuromyelitis optica: changing concepts. J Neuroimmunol 2007 Jul; 187(1-2):126-38. Epub 2007 May 21.
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  37. Wingerchuk DM, Lucchinetti CF. Comparative immunopathogenesis of acute disseminated encephalomyelitis, neuromyelitis optica, and multiple sclerosis. Curr Opin Neurol 2007 Jun; 20(3):343-50.
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  38. Vana AC, Lucchinetti CF, Le TQ, Armstrong RC. Myelin transcription factor 1 (Myt1) expression in demyelinated lesions of rodent and human CNS. Glia 2007 May; 55(7):687-97.
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  39. Roemer SF, Parisi JE, Lennon VA, Benarroch EE, Lassmann H, Bruck W, Mandler RN, Weinshenker BG, Pittock SJ, Wingerchuk DM, Lucchinetti CF. Pattern-specific loss of aquaporin-4 immunoreactivity distinguishes neuromyelitis optica from multiple sclerosis. Brain 2007 May; 130(Pt 5):1194-205.
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  40. Metz I, Lucchinetti CF, Openshaw H, Garcia-Merino A, Lassmann H, Freedman MS, Atkins HL, Azzarelli B, Kolar OJ, Bruck W. Autologous haematopoietic stem cell transplantation fails to stop demyelination and neurodegeneration in multiple sclerosis. Brain 2007 May; 130(Pt 5):1254-62.
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  41. Lassmann H, Bruck W, Lucchinetti CF. The immunopathology of multiple sclerosis: an overview. Brain Pathol 2007 Apr; 17(2):210-8.
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  42. Pittock SJ, Lucchinetti CF. The pathology of MS: new insights and potential clinical applications. Neurologist 2007 Mar; 13(2):45-56.
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  43. Pirko I, Lucchinetti CF, Sriram S, Bakshi R. Gray matter involvement in multiple sclerosis. Neurology 2007 Feb 27; 68(9):634-42.
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  44. Wingerchuk DM, Pittock SJ, Lucchinetti CF, Lennon VA, Weinshenker BG. A secondary progressive clinical course is uncommon in neuromyelitis optica. Neurology 2007 Feb 20; 68(8):603-5.
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  45. Kutzelnigg A, Faber-Rod JC, Bauer J, Lucchinetti CF, Sorensen PS, Laursen H, Stadelmann C, Bruck W, Rauschka H, Schmidbauer M, Lassmann H. Widespread demyelination in the cerebellar cortex in multiple sclerosis. Brain Pathol 2007 Jan; 17(1):38-44.
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  46. Pittock SJ, Reindl M, Achenbach S, Berger T, Bruck W, Konig F, Morales Y, Lassmann H, Bryant S, Moore SB, Keegan BM, Lucchinetti CF. Myelin oligodendrocyte glycoprotein antibodies in pathologically proven multiple sclerosis: frequency, stability and clinicopathologic correlations. Mult Scler 2007 Jan; 13(1):7-16.
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  47. Hu WT, Kantarci OH, Merritt JL, McGrann P, Dyck PJB, Lucchinetti CF, Tippmann-Peikert M. Ornithine transcarbamylase deficiency presenting as encephalopathy during adulthood following bariatric surgery. Arch Neurol 2007 Jan; 64(1):126-8.
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  48. Pittock SJ, Reindl M, Achenboch S, Berger T, Bruck W, Konig F, Morales Y, Lassmann H, Bryants S, Moore SB, Keegan BM, Lucchinetti CF. Myelin oligodendrocyte glycoprotein antibodies in pathologically proven multiple sclerosis: frequency, stability and clinicopathologic correlations. Mult Scler 2007 Jan; 13(1):7-16.
  49. Lucchinetti C. Advances in Neuropathology of MS.Pathogenic and Therapeutic Implications. Continuum 2007; 13(5):86-116.
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  50. Patrikios P, Stadelmann C, Kutzelnigg A, Rauschka H, Schmidbauer M, Laursen H, Sorensen PS, Bruck W, Lucchinetti C, Lassmann H. Remyelination is extensive in a subset of multiple sclerosis patients. Brain 2006 Dec; 129(Pt 12):3165-72. Epub 2006 Aug 18.
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  51. Miller RC, Lachance DH, Lucchinetti CF, Keegan BM, Gavrilova RH, Brown PD, Weinshenker BG, Rodriguez M. Multiple sclerosis, brain radiotherapy, and risk of neurotoxicity: the Mayo Clinic experience. Int J Radiat Oncol Biol Phys 2006 Nov 15; 66(4):1178-86. Epub 2006 Sep 11.
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  52. Pittock SJ, Lucchinetti CF. Inflammatory transverse myelitis: evolving concepts. Curr Opin Neurol 2006 Aug; 19(4):362-8.
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  53. Pittock SJ, Weinshenker BG, Lucchinetti CF, Wingerchuk DM, Corboy JR, Lennon VA. Neuromyelitis optica brain lesions localized at sites of high aquaporin 4 expression. Arch Neurol 2006 Jul; 63(7):964-8.
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  54. Wingerchuk DM, Lennon VA, Pittock SJ, Lucchinetti CF, Weinshenker BG. Revised diagnostic criteria for neuromyelitis optica. Neurology 2006 May 23; 66(10):1485-9.
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  55. Pittock SJ, Weinshenker BG, Noseworthy JH, Lucchinetti CF, Keegan M, Wingerchuk DM, Carter J, Shuster E, Rodriguez M. Not every patient with multiple sclerosis should be treated at time of diagnosis. Arch Neurol 2006 Apr; 63(4):611-4.
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  56. Weinshenker BG, Wingerchuk DM, Vukusic S, Linbo L, Pittock SJ, Lucchinetti CF, Lennon VA. Neuromyelitis optica IgG predicts relapse after longitudinally extensive transverse myelitis. Ann Neurol 2006 Mar; 59(3):566-9.
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  57. Schwartz KM, Erickson BJ, Lucchinetti C. Pattern of T2 hypointensity associated with ring-enhancing brain lesions can help to differentiate pathology. Neuroradiology 2006 Mar; 48(3):143-9. Epub 2006 Jan 31.
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  58. Pittock SJ, Lennon VA, Krecke K, Wingerchuk DM, Lucchinetti CF, Weinshenker BG. Brain abnormalities in neuromyelitis optica. Arch Neurol 2006 Mar; 63(3):390-6.
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  59. Castillo P, Woodruff B, Caselli R, Vernino S, Lucchinetti C, Swanson J, Noseworthy J, Aksamit A, Carter J, Sirven J, Hunder G, Fatourechi V, Mokri B, Drubach D, Pittock S, Lennon V, Boeve B. Steroid-responsive encephalopathy associated with autoimmune thyroiditis. Arch Neurol 2006 Feb; 63(2):197-202.
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  60. Morales Y, Parisi JE, Lucchinetti CF. The pathology of multiple sclerosis: evidence for heterogeneity. Adv Neurol 2006; 98:27-45.
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  61. Weinshenker BG, Wingerchuk DM, Pittock SJ, Lucchinetti CF, Lennon VA. NMO-IgG: a specific biomarker for neuromyelitis optica. Dis Markers 2006; 22(4):197-206.
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  62. Fox RJ, Kivisakk P, Lee JC, Tucky B, Lucchinetti C, Rudick RA, Ransohoff RM. Chemokine receptors as biomarkers in multiple sclerosis. Dis Markers 2006; 22(4):227-33.
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  63. Morales Y, Parisi JE, Lucchinetti CF. The pathology of multiple sclerosis: evidence for heterogeneity Advances in Neurology 2006; 98:27-45.
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  64. Fox RJ, Pia K, Jar-Chi L, Tucky B, Lucchinetti CF, Fisher E, Rudick R, Ransohoff R. Chemokine receptors as biomarkers in multiple sclerosis. Disease Markers 2006; 22(4):227-33.
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  65. Kantarci OH, Morales Y, Ziemer PA, Hebrink DD, Mahad DJ, Atkinson EJ, Achenbach SJ, De Andrade M, Mack M, Ransohoff RM, Lassmann H, Bruck W, Weinshenker BG, Lucchinetti CF. CCR5 Delta 32 polymorphism effects on CCR5 expression, patterns of immunopathology and disease course in multiple sclerosis. J Neuroimmunol 2005 Dec; 169(1-2):137-43 Epub 2005 Sep 22.
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  66. Pittock SJ, McClelland RL, Achenbach SJ, Konig F, Bitsch A, Bruck W, Lassmann H, Parisi JE, Scheithauer BW, Rodriguez M, Weinshenker BG, Lucchinetti CF. Clinical course, pathological correlations, and outcome of biopsy proved inflammatory demyelinating disease. J Neurol Neurosurg Psychiatry 2005 Dec; 76(12):1693-7.
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  67. Kutzelnigg A, Lucchinetti CF, Stadelmann C, Bruck W, Rauschka H, Bergmann M, Schmidbauer M, Parisi JE, Lassmann H. Cortical demyelination and diffuse white matter injury in multiple sclerosis. Brain 2005 Nov; 128(Part 11):2705-12.
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  68. Frohman EM, Filippi M, Stuve O, Waxman SG, Corboy J, Phillips JT, Lucchinetti C, Wilken J, Karandikar N, Hemmer B, Monson N, De Keyser J, Hartung H, Steinman L, Oksenberg JR, Cree BAC, Hauser S, Racke MK. Characterizing the mechanisms of progression in multiple sclerosis - Evidence and new hypotheses for future directions. Arch Neurol 2005 Sep; 62(9):1345-56.
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  69. Keegan M, Konig F, McClelland R, Bruck W, Morales Y, Bitsch A, Panitch H, Lassmann H, Weinshenker B, Rodriguez M, Parisi J, Lucchinetti CF. Relation between humoral pathological changes in multiple sclerosis and response to therapeutic plasma exchange. Lancet 2005 Aug 13-19; 366(9485):579-82.
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  70. Cox A, Coles A, Antoun N, Malik O, Lucchinetti C, Compston A. Recurrent myelitis and optic neuritis in a 29-year-old woman. Lancet Neurol 2005 Aug; 4(8):510-6.
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  71. Pittock SJ, Lucchinetti CF, Parisi JE, Benarroch EE, Mokri B, Stephan CL, Kim KK, Killmann MW, Lennon VA. Amphiphysin autoimmunity: paraneoplastic accompaniments. Ann Neurol 2005 Jul; 58(1):96-107.
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  72. Stadelmann C, Ludwin S, Tabira T, Guseo A, Lucchinetti CF, Leel-Ossy L, Ordinario AT, Bruck W, Lassmann H. Tissue preconditioning may explain concentric lesions in Balo's type of multiple sclerosis. Brain 2005 May; 128(Part 5):979-87.
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  73. Wingerchuk DM, Benarroch EE, O'Brien PC, Keegan BM, Lucchinetti CF, Noseworthy JH, Weinshenker BG, Rodriguez M. A randomized controlled crossover trial of aspirin for fatigue in multiple sclerosis. Neurology 2005 Apr 12; 64(7):1267-9.
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  74. Lucchinetti CF, Parisi J, Bruck W. The pathology of multiple sclerosis. Neurol Clin 2005 Feb; 23(1):77-105.
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  75. Lucchinetti CF. Update on the international project on pathologic correlates in MS. Mult Scler 2005 Feb; 11(1):99-100.
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  76. Lennon VA, Wingerchuk DM, Kryzer TJ, Pittock SJ, Lucchinetti CF, Fujihara K, Nakashima I, Weinshenker BG. A serum autoantibody marker of neuromyelitis optica: distinction from multiple sclerosis. Lancet 2004 Dec 11-17; 364(9451):2106-12.
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  77. Lucchinetti C, Bruck W. The pathology of primary progressive multiple sclerosis. Mult Scler 2004 Jun; 10(Suppl 1):S23-S30.
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  78. Mahad DJ, Trebst C, Kivisakk P, Staugaitis SM, Tucky B, Wei T, Lucchinetti CF, Lassmann H, Ransohoff RM. Expression of chemokine receptors CCR1 and CCR5 reflects differential activation of mononuclear phagocytes in pattern II and pattern III multiple sclerosis lesions. J Neuropathol Exp Neurol 2004 Mar; 63(3):262-73.
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  79. Hoftberger R, Aboul-Enein F, Brueck W, Lucchinetti C, Rodriguez M, Schmidbauer M, Jellinger K, Lassmann H. Expression of major histocompatibility complex Class I molecules on the different cell types in multiple sclerosis lesions. Brain Pathol 2004 Jan; 14(1):43-50.
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  80. Mahad DJ, Trebst C, Kivisaak P, Staugaitis SM, Wei TW, Tuckey B, Lucchinetti CF, Lassmann H, Ransohoff R. Distinct patterns of chemokine receptor expression on phagocytic macrophages in pattern II and pattern III MS lesions. J Neuropath Exp Neurol 2004; 63(3):262-73.
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  81. Pittock SJ, Lucchinetti CF, Lennon VA. Anti-neuronal nuclear autoantibody type 2: Paraneoplastic accompaniments. Ann Neurol 2003 May; 53(5):580-7.
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  82. Trebst C, Staugaitis SM, Kivisakk P, Mahad D, Cathcart MK, Tucky B, Wei T, Rani MRS, Horuk R, Aldape KD, Pardo CA, Lucchinetti CF, Lassmann H, Ransohoff RM. CC chemokine receptor 8 in the central nervous system is associated with phagocytic macrophages. Am J Pathol 2003 Feb; 162(2):427-38.
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  83. Aboul-Enein F, Rauschka H, Kornek B, Stadelmann C, Stefferl A, Bruck W, Lucchinetti C, Schmidbauer M, Jellinger K, Lassmann H. Preferential loss of myelin-associated glycoprotein reflects hypoxia-like white matter damage in stroke and inflammatory brain diseases. Journal of Neuropathology & Experimental Neurology 2003 Jan; 62(1):25-33.
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  84. Trebst C, Staugaitis SM, Kivisakk P, Mahad D, Cathcart MK, Tucky B, Wei T, Rani SMR, Horuk R, Aldape KD, Pardo CA, Lucchinetti CF, Lassmann H, Ransohoff RM. CC Chemokine Receptor 8 (CCR8) in the Central Nervous Syste, is Associated with Phagocytic Macrophages. Am J Path 2003; 162(2):427-38.
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  85. O'Connor P, Fleming P, Gray T, Jacobs L, Miller C, Munschauer F, Kinkel RP, Bolibrush D, Cohen J, Freedman M, Webb U, Rabinowicz H, Metz LM, Patry D, Yeung M, Peters S, Hashimoto S, Morrison W, Oger J, Panitch H, Costello K, Bever C, Stuart W, Court D, St MRI predictors of early conversion to clinically definite MS in the CHAMPS Placebo Group. Neurology 2002 Oct 8;59(7):998-1005.
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  86. O'Connor P, Fleming P, Gray T, Jacobs L, Miller C, Munschaner F, Kinkel RP, Bolibrush D, Cohen J, Freedman M, Webb U, Rabinowicz H, Metz LM, Patry D, Yeung M, Peters S, Hashimoto S, Morrison W, Oger J, Panitch H, Costello K, Bever C, Stuart W, Court D, St Predictors of short-term disease activity following a first clinical demyelinating event: Analysis of the CHAMPS Placebo Group. Mult Scler 2002 Oct;8(5):405-9.
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  87. O'Connor P, Fleming P, Gray T, Jacobs L, Miller C, Munschauer F, Kinkel RR, Bolibrush D, Cohen J, Freedman M, Webb U, Rabinowicz H, Metz L, Davis A, Patry D, Hashimoto S, Morrison W, Oger J, Panitch H, Costello K, Bever C, Stuart W, Court D, Stuart D, Tor Baseline MRI characteristics of patients at high risk for multiple sclerosis: Results from the CHAMPS Trial. Mult Scler 2002 Aug; 8(4):330-8.
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  88. Lucchinetti CF, Mandler RN, McGavern D, Bruck W, Gleich G, Ransohoff RM, Trebst C, Weinshenker B, Wingerchuk D, Parisi JE, Lassmann H. A role for humoral mechanisms in the pathogenesis of Devic's neuromyelitis optica. Brain 2002 Jul; 125(7):1450-61.
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  89. Bruck W, Lucchinetti C, Lassmann H. The pathology of primary progressive multiple sclerosis. Mult Scler 2002 Apr; 8(2):93-7.
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  90. Martinez-Arizala A, Barnes G, Benjamin S, Bowen J, Cutter N, Dietrich D, Dowling M, Griffin J, Irani D, Jorens P, Kaplin A, Katz J, Kerr D, Levy C, Lucchinetti CF, Lynn J, Mandler R, McDonald J, Morrison L, Pardo C, Pidcock F, Ransohoff R, Trovato M, Wege Proposed diagnostic criteria and nosology of acute transverse myelitis. Neurology 2002:499-505.
  91. Scarisbrick IA, Blaber SI, Lucchinetti CF, Genain CP, Blaber M, Rodriguez M. Activity of a newly identified serine protease in immune-mediated demyelination. Brain 2002; 125:1-14.
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  92. Targonski PV, Schiebel NE, Lucchinetti CN. Minocyoline-associated idiopathic intracranial hypertension in a patient presenting to the emergency department. Internet Journal of Emergency & Intensive Care Medicine 2002; 6(1):8p.
  93. Bruck W, Lucchinetti CF, Lassmann H. Review: The pathology of primary progressive multiple sclerosis. Multiple Sclerosis 2002; 8:93-7.
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  94. O'Connor P, Fleming P, Gray T, Jacobs L, Miller C, Munschauer F, Kinkel RP, Bolibrush D, Cohen J, Freedman M, Webb U, Rabinowicz H, Metz LM, Patry D, Yeung M, Peters S, Hashimoto S, Morrison W, Oger J, Panitch H, Costello K, Bever C, Stuart W, Court D, St Interferon beta-1 a for optic neuritis patients at high risk for multiple sclerosis. Am J Ophthalmol 2001 Oct; 132(4):463-71.
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  95. Bitsch A, Kuhlmann T, Stadelmann C, Lassmann H, Lucchinetti C, Bruck W. A longitudinal MRI study of histopathologically defined hypointense multiple sclerosis lesions. Ann Neurol 2001 Jun; 49(6):793-6.
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  96. Lucchinetti C, Bruck W, Noseworthy J. Multiple sclerosis: recent developments in neuropathology, pathogenesis, magnetic resonance imaging studies and treatment. Curr Opin Neurol 2001 Jun; 14(3):259-69.
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  97. Wingerchuk DM, Lucchinetti CF, Noseworthy JH. Multiple sclerosis: current pathophysiological concepts. Lab Invest 2001 Mar; 81(3):263-81.
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  98. Lassmann H, Bruck W, Lucchinetti C. Heterogeneity of multiple sclerosis pathogenesis: implications for diagnosis and therapy. Trends Mol Med 2001 Mar; 7(3):115-21.
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  99. Jacobs LD, Beck RW, Simon JH, Kinkel RP, Brownscheidle CM, Murray TJ, Simonian NA, Slasor PJ, Sandrock AW, the CHAMPS Study Group. Intramuscular interferon beta-1a therapy initiated during a first demyelinating event in multiple sclerosis. N Engl J Med 2000 Sep 28; 343(13):898-904.
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  100. Noseworthy JH, Lucchinetti C, Rodriguez M, Weinshenker BG. Multiple sclerosis. N Engl J Med 2000 Sep 28; 343(13):938-52. Review
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  101. Lucchinetti C, Bruck W, Parisi J, Scheithauer B, Rodriguez M, Lassmann H. Heterogeneity of multiple sclerosis lesions: implications for the pathogenesis of demyelination. Ann Neurol 2000 Jun; 47(6):707-17.
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  102. Lucchinetti C, Bruck W, Parisi J, Scheithauer B, Rodriguez M, Lassmann H. A quantitative analysis of oligodendrocytes in multiple sclerosis lesions. A study of 113 cases. Brain 1999 Dec; 122(Pt 12):2279-95.
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  103. Weinshenker BG, O'Brien PC, Petterson TM, Noseworthy JH, Lucchinetti CF, Dodick DW, Pineda AA, Stevens LN, Rodriguez M. A randomized trial of plasma exchange in acute central nervous system inflammatory demyelinating disease. Ann Neurol 1999 Dec; 46(6):878-86.
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  104. Rodriguez M, Lucchinetti CF. Is apoptotic death of the oligodendrocyte a critical event in the pathogenesis of multiple sclerosis? Neurology 1999 Nov 10; 53(8):1615-6.
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  105. Kuhlmann T, Lucchinetti C, Zettl UK, Bitsch A, Lassmann H, Bruck W. Bcl-2-expressing oligodendrocytes in multiple sclerosis lesions. Glia 1999 Oct; 28(1):34-9.
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  106. Auger RG, Windebank AJ, Lucchinetti CF, Chalk CH. Role of the blink reflex in the evaluation of sensory neuronopathy. Neurology 1999 Jul 22; 53(2):407-8.
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  107. Sorensen TL, Tani M, Jensen J, Pierce V, Lucchinetti C, Folcik VA, Qin S, Rottman J, Sellebjerg F, Strieter RM, Frederiksen JL, Ransohoff RM. Expression of specific chemokines and chemokine receptors in the central nervous system of multiple sclerosis patients. J Clin Invest 1999 Mar; 103(6):807-15.
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  108. Drescher KM, Rivera-Quinones C, Lucchinetti CF, Rodriguez M. Failure of treatment with Linomide or oral myelin tolerization to ameliorate demyelination in a viral model of multiple sclerosis. J Neuroimmunol 1998 Aug 1; 88(1-2):111-9.
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  109. Lucchinetti CF, Kimmel DW, Lennon VA. Paraneoplastic and oncologic profiles of patients seropositive for type 1 antineuronal nuclear autoantibodies. Neurology 1998 Mar; 50(3):652-7.
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  110. Petty GW, Engel AG, Younge BR, Duffy J, Yanagihara T, Lucchinetti CF, Bartleson JD, Parisi JE, Kasperbauer JL, Rodriguez M. Retinocochleocerebral vasculopathy. Medicine (Baltimore) 1998 Jan; 77(1):12-40.
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  111. Weinshenker BG, Lucchinetti CF. Acute leukoencephalopathies: differential diagnosis and investigation. Neurologist 1998; 4(3):148-66.
  112. Lucchinetti CF, Brueck W, Rodriguez M, Lassmann H. Multiple sclerosis: lessons from neuropathology. Semin Neurol 1998; 18(3):337-49.
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  113. Lucchinetti CF, Kiers L, O'Duffy A, Gomez MR, Cross S, Leavitt JA, O'Brien P, Rodriguez M. Risk factors for developing multiple sclerosis after childhood optic neuritis. Neurology 1997 Nov; 49(5):1413-8.
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  114. Lucchinetti CF, Kimmel DW, Pavelko K, Rodriguez M. 5-Fluorouracil and levamisole exacerbate demyelination in susceptible mice infected with Theiler's virus. Exp Neurol 1997 Sep; 147(1):123-9.
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  115. Lucchinetti CF, Rodriguez M. The controversy surrounding the pathogenesis of the multiple sclerosis lesion. Mayo Clin Proc 1997 Jul; 72(7):665-78.
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  116. Lassmann H, Bruck W, Lucchinetti C, Rodriguez M. Remyelination in multiple sclerosis. Mult Scler 1997 Apr; 3(2):133-6.
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  117. Lucchinetti CF, Noseworthy JH, Rodriguez M. Promotion of endogenous remyelination in multiple sclerosis. Mult Scler 1997 Apr; 3(2):71-75.
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  118. Lucchinetti CF, Bruck W, Rodriguez M, Lassmann H. Distinct patterns of multiple sclerosis pathology indicates heterogeneity in pathogenesis. Brain Pathol 1996 Jul; 6(3):259-274.
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  119. Kerns JM, Lucchinetti C. Electrical field effects on crushed nerve regeneration. Exp Neurol 1992 Jul; 117(1):71-80.
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  120. Kerns JM, Braverman B, Mathew A, Lucchinetti C, Ivankovich AD. A comparison of cryoprobe and crush lesions in the rat sciatic nerve. Pain 1991 Oct; 47(1):31-9.
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  121. Rodriguez M, Lucchinetti CF, Clark RJ, Yakash TL, Markowitz H, Lennon VA. Immunoglobulins and complement in demyelination induced in mice by Theiler's virus. J Immunol 1988 Feb 1; 140(3):800-6.
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