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Publications - Rhett P . Ketterling, M.D.

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  1. Sukov WR, Cheville JC, Giannini C, Carlson AW, Shearer BM, Sinnwell JP, Ketterling RP. Isochromosome 12p and polysomy 12 in primary central nervous system germ cell tumors: frequency and association with clinicopathologic features. Hum Pathol 2009 Oct 02. [Epub ahead of print]
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  2. Steensma DP, Neiger JD, Porcher JC, Keats JJ, Bergsagel PL, Dennis TR, Knudson RA, Jenkins RB, Santana-Davila R, Kumar R, Ketterling RP. Rearrangements and amplification of IER3 (IEX-1) represent a novel and recurrent molecular abnormality in myelodysplastic syndromes. Cancer Res 2009 Oct 1; 69(19):7518-23. Epub 2009 Sep 22.
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  3. Fernandez HF, Sun ZX, Yao XP, Litzow MR, Luger SM, Paietta EM, Racevskis J, Dewald GW, Ketterling RP, Bennett JM, Rowe JM, Lazarus HM, Tallman MS. Anthracycline dose intensification in acute myeloid leukemia. N Engl J Med 2009 Sep 24; 361(13):1249-59.
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  4. Fernandez HF, Sun ZX, Yao XP, Litzow MR, Luger SM, Paietta EM, Racevskis J, Dewald GW, Ketterling RP, Bennett JM, Rowe JM, Lazarus HM, Tallman MS. Anthracycline dose intensification in acute myeloid leukemia. N Engl J Med 2009 Sep 24; 361(13):1249-59.
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  5. Shah SS, Ketterling RP, Goetz MP, Ingle JN, Reynolds CA, Perez EA, Chen B. Impact of American Society of Clinical Oncology/College of American Pathologists guideline recommendations on HER2 interpretation in breast cancer. Hum Pathol 2009 Sep 15. [Epub ahead of print]
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  6. Sukov WR, Ketterling RP, Lager DJ, Carlson AW, Sinnwell JP, Chow GK, Jenkins RB, Cheville JC. CCND1 rearrangements and cyclin D1 overexpression in renal oncocytomas: frequency, clinicopathologic features, and utility in differentiation from chromophobe renal cell carcinoma. Hum Pathol 2009 Sep; 40(9):1296-303. Epub 2009 Apr 22.
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  7. Gangat N, Tefferi A, Thanarajasingam G, Patnaik M, Schwager S, Ketterling R, Wolanskyj AP. Cytogenetic abnormalities in essential thrombocythemia: prevalence and prognostic significance. Eur J Haematol 2009 Jul; 83(1):17-21. Epub 2009 Feb 19.
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  8. Fink SR, Belongie KJ, Paternoster SF, Smoley SA, Pardanani AD, Tefferi A, Van Dyke DL, Ketterling RP. Validation of a new three-color fluorescence in situ hybridization (FISH) method to detect CHIC2 deletion, FIP1L1/PDGFRA fusion and PDGFRA translocations. Leuk Res 2009 Jun; 33(6):843-6. Epub 2008 Dec 31.
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  9. Yin CC, Lin KL, Ketterling RP, Knudson RA, Barron LL, Huh YO, Luthra R, Medeiros LJ, Keating MJ, Abruzzo LV. Chronic lymphocytic leukemia with t(2;14)(p16;q32) is associated with BCL11A/IgH rearrangement, atypical morphology, unmutated IgVH genes, and an aggressive clinical course. Amer J of Clin Path May 2009; 131(5):663-70.
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  10. Yin CC, Lin KIC, Ketterling RP, Knudson RA, Medeiros LJ, Barron LL, Huh YO, Luthra R, Keating MJ, Abtuzzo LV. Chronic lymphocytic leukemia with t(2;14)(p16;q32) involves the BCL11A and IgH genes and is associated with atypical morphologic features and unmutated IgV(H) genes. Am J Clin Pathol 2009 May; 131(5):663-70.
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  11. Hussein K, Huang J, Lasho T, Pardanani A, Mesa RA, Williamson CM, Ketterling RP, Hanson CA, Van Dyke DL, Tefferi A. Karyotype complements the International Prognostic Scoring System for primary myelofibrosis. Eur J Haematol 2009 Apr; 82(4):255-9. Epub 2008 Feb 10.
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  12. Scheithauer BW, Silva AI, Ketterling RP, Pula JH, Lininger JF, Krinock MJ. Rosette-forming glioneuronal tumor: report of a chiasmal-optic nerve example in neurofibromatosis type 1: special pathology report. Neurosurgery 2009 Apr; 64(4):E771-2; discussion E772.
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  13. Neder L, Scheithauer BW, Turel KE, Arnesen MA, Ketterling RP, Jin L, Moynihan TJ, Giannini C, Meyer FB. Desmoplastic small round cell tumor of the central nervous system: report of two cases and review of the literature. Virchows Arch 2009 Apr; 454(4):431-9. Epub 2009 Mar 05.
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  14. Bryce AH, Ketterling RP, Gertz MA, Lacy M, Knudson RA, Zeldenrust S, Kumar S, Hayman S, Buadi F, Kyle RA, Greipp PR, Lust JA, Russell S, Rajkumar SV, Fonseca R, Dispenzieri A. Translocation t(11;14) and survival of patients with light chain (AL) amyloidosis. Haematologica 2009 Mar; 94(3):380-6. Epub 2009 Feb 11.
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  15. Mesa RA, Hanson CA, Ketterling RP, Schwager S, Knudson RA, Tefferi A. Trisomy 13: Prevalence and clinicopathologic correlates of another potentially lenalidomide-sensitive cytogenetic abnormaliry. Blood 2009 Jan 29; 113(5):1200-1.
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  16. Sukov W, Ketterling RP, Carlson A, Sinnwell J, Jenkins RB, Lager D, Cheville J. CCND1 rearrangements and cyclin D1 overexporession in renal oncocytomas: frequency, clinicopathologic features and utility in differentiation from chromophobe renal cell carcinoma. Hum Pathol 2009 Epub 2009 Apr 20.
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  17. Santana-Davila R, Tefferi A, Holtan SG, Ketterling RP, Dewald GW, Knudson RA, Steensma DP, Chen D, Hoyer JD, Hanson CA. Primary myelofibrosis is the most frequent myeloproliferative neoplasm associated with del(5q): clinicopathologic comparison of del(5q)-positive and -negative cases. Leuk Res 2008 Dec; 32(12):1927-30. Epub 2008 Jun 09.
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  18. Santana-Davila R, Tefferi A, Holtan SG, Ketterling RP, Dewald GW, Knudson RA, Steensma DP, Chen D, Hoyer JD, Hanson CA. Primary myelofibrosis is the most frequent myeloproliferative neoplasm associated with del(5q): Clinicopathologic comparison of del(5q)-positive and -negative cases. Leuk Res 2008 Dec; 32(12):1927-30.
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  19. Scheithauer BW, Kovacs K, Horvath E, Kim DS, Osamura RY, Ketterling RP, Lloyd RV, Kim OL. Pituitary blastoma. Acta Neuropathol 2008 Dec; 116(6):657-66. Epub 2008 Jun 13.
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  20. Bryce AH, Ketterling RP, Gertz MA, Lacy M, Knudson RA, Kumar S, Kyle RA, Fonseca R, Greipp PR, Lust JA, Rajkumar VS, Hayman SR, Buadi F, Russell SJ, Zeldenrust SR, Dispenzieri A. A novel report of cig-FISH and cytogenetics in POEMS syndrome. Am J Hematol 2008 Nov; 83(11):840-1.
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  21. Chen D, Hoyer JD, Ketterling RP, Tefferi A, Steensma DP, Holtan SG, Santana-Davila R, Porrata LF, Dewald GW, Hanson CA. Dysgranulopoiesis is an independent adverse prognostic factor in chronic myeloid disorders with an isolated interstitial deletion of chromosome 5q. Leukemia 2008 Oct 23. [Epub ahead of print]
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  22. Hussein K, Ketterling RP, Dewald GW, Van Dyke DL, Mesa R, Hanson CA, Tefferi A. Peripheral blood cytogenetic studies in myelofibrosis: overall yield and comparison with bone marrow cytogenetic studies. Leuk Res 2008 Oct; 32(10):1597-600. Epub 2008 Feb 01.
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  23. Arendt BK, Ramirez-Alvarado M, Sikkink LA, Keats JJ, Ahmann GJ, Dispenzieri A, Fonseca R, Ketterling RP, Knudson RA, Mulvihill EM, Tschumper RC, Wu X, Zeldenrust SR, Jelinek DF. Biologic and genetic characterization of the novel amyloidogenic lambda light chain-secreting human cell lines, ALMC-1 and ALMC-2. Blood 2008 Sep 1; 112(5):1931-41. Epub 2008 Jun 20.
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  24. Holtan SG, Santana-Davila R, Dewald GW, Khetterling RP, Knudson RA, Hoyer JD, Chen D, Hanson CA, Porrata L, Tefferi A, Steensma DP. Myelodysplastic syndromes associated with interstitial deletion of chromosome 5q: clinicopathologic correlations and new insights from the pre-lenalidomide era. Am J Hematol 2008 Sep; 83(9):708-13.
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  25. Tiedemann RE, Gonzalez-Paz N, Kyle RA, Santana-Davila R, Price-Troska T, Van Wier SA, Chng WJ, Ketterling RP, Gertz MA, Henderson K, Greipp PR, Dispenzieri A, Lacy MQ, Rajkumar SV, Bergsagel PL, Stewart AK, Fonseca R. Genetic aberrations and survival in plasma cell leukemia. Leukemia 2008 May; 22(5):1044-52. Epub 2008 Jan 24.
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  26. Hussein K, Ketterling RP, Hulshizer RL, Kuffel DG, Wiktor AE, Hanson CA, Tefferi A, Van Dyke DL. Peripheral blood cytogenetic studies in hematological neoplasms: predictors of obtaining metaphases for analysis. Eur J Haematol 2008 Apr; 80(4):318-21. Epub 2007 Dec 18.
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  27. Hanson CA, Steensma DP, Hodnefield JM, Nguyen PL, Hoyer JD, Viswanatha DS, Zou Y, Knudson RA, Van Dyke DL, Ketterling RP. Isolated trisomy 15: a clonal chromosome abnormality in bone marrow with doubtful hematologic significance. Am J Clin Pathol 2008 Mar; 129(3):478-85.
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  28. Gangat N, Strand J, Lasho TL, Finke CM, Knudson RA, Pardanani A, Li CY, Ketterling RP, Tefferi A. Cytogenetic studies at diagnosis in polycythemia vera: clinical and JAK2V617F allele burden correlates. Eur J Haematol 2008 Mar; 80(3):197-200. Epub 2007 Dec 07.
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  29. Santana-Davila R, Holtan SG, Dewald GW, Ketterling RP, Knudson RA, Hanson CA, Steensma DP, Tefferi A. Chromosome 5q deletion: specific diagnoses and cytogenetic details among 358 consecutive cases from a single institution. Leuk Res 2008 Mar; 32(3):407-11. Epub 2007 Aug 20.
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  30. Hussein K, Ketterling R, Dewald G, VanDyke D, Mesa R, Hanson C, Tefferi A. Peripheral blood cytogenetic studies in myelofibrosis: Overall yield and comparison with bone marrow cytogenetic studies. Journal of Leukemia Research 2007 Dec; 10:1016.
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  31. Shearer BM, Thorland EC, Gonzales PR, Ketterling RP. Evaluation of a commercially available focused aCGH platform for the detection of constitutional chromosome anomalies. Am J Med Genet A 2007 Oct 15; 143A(20):2357-70.
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  32. Tefferi A, Strand JJ, Lasho TL, Knudson RA, Finke CM, Gangat N, Pardanani A, Hanson CA, Ketterling RP. Bone marrow JAK2V617F allele burden and clinical correlates in polycythemia vera. Leukemia 2007 Sep; 21(9):2074-5. Epub 2007-05-03.
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  33. Pardanani A, Lasho TL, Finke C, Mesa RA, Hogan WJ, Ketterling RP, Gilliland DG, Tefferi A. Extending Jak2V617F and MplW515 mutation analysis to single hematopoietic colonies and B and T lymphocytes. Stem Cells 2007 Sep; 25(9):2358-62. Epub 2007 May 31.
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  34. Thorland EC, Gonzales PR, Gliem TJ, Wiktor AE, Ketterling RP. Comprehensive validation of array comparative genomic hybridization platforms: how much is enough? Genet Med 2007 Sep; 9(9):632-41.
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  35. Kreuziger LM, Porcher JC, Ketterling RP, Steensma DP. An MLL-SEPT9 fusion and t(11;17)(q23;q25) associated with de novo myelodysplastic syndrome. Leuk Res 2007 Aug; 31(8):1145-8. Epub 2007 Jan 23.
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  36. Tefferi A, Lasho TL, Mesa RA, Pardanani A, Ketterling RP, Hanson CA. Lenalidomide therapy in del(5)(q31)-associated myelofibrosis: cytogenetic and JAK2V617F molecular remissions. Leukemia 2007 Aug; 21(8):1827-8. Epub 2007 Apr 26.
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  37. Kittur J, Knudson RA, Lasho TL, Finke CM, Gangat N, Wolanskyj AP, Li CY, Wu W, Ketterling RP, Pardanani A, Tefferi A. Clinical correlates of JAK2V617F allele burden in essential thrombocythemia. Cancer 2007 Jun 1; 109(11):2279-84.
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  38. Sukov WR, Cheville JC, Carlson AW, Shearer BM, Piatigorsky EJ, Grogg KL, Sebo TJ, Sinnwell JP, Ketterling RP. Utility of ALK-1 protein expression and ALK rearrangements in distinguishing inflammatory myofibroblastic tumor from malignant spindle cell lesions of the urinary bladder. Mod Pathol 2007 May; 20(5):592-603.
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  39. Bryce AH, Ketterling RP, Gertz MA, Kyle RA, Lust JA, Fonseca R, Lacy M, Greipp PR, Witzig TA, Rajkumar S, Dispenzieri A. POEMS syndrome, or osteosclerotic myeloma, is an uncommon plasma cell disorder associated with Peripheral neuropathy, Organomegaly, Endocrinopathy, M protein, and Skin changes, as well as bone lesions, Castlemans disease, and edema. Mod Pathol 2007 May; 20(5):592-603.
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  40. Knudson RA, Shearer BM, Ketterling RP. Automated Duet spot counting system and manual technologist scoring using dual-fusion fluorescence in situ hybridization (D-FISH) strategy: comparison and application to FISH minimal residual disease testing in patients with chronic myeloid leukemia. Cancer Genet Cytogenet 2007 May; 175(1):8-18.
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  41. Vaklavas C, Tefferi A, Butterfield J, Ketterling R, Verstovsek S, Kantarjian H, Pardanani A. 'Idiopathic' eosinophilia with an Occult T-cell clone: prevalence and clinical course. Leuk Res 2007 May; 31(5):691-4.
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  42. Stevens R, Almanaseer I, Gonzalez M, Caglar D, Knudson RA, Ketterling RP, Schrock DS, Seemayer TA, Bridge JA. Analysis of HER2 gene amplification using an automated fluorescence in situ hybridization signal enumeration system. J Mol Diagn 2007 Apr; 9(2):144-50.
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  43. Chng WJ, Ketterling RP, Fonseca R. Analysis of genetic abnormalities provides insights into genetic evolution of hyperdiploid myeloma. Genes Chromosomes Cancer 2006 Dec; 45(12):1111-20.
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  44. Fonseca R, Van Wier SA, Chng WJ, Ketterling R, Lacy MQ, Dispenzieri A, Bergsagel PL, Rajkumar SV, Greipp PR, Litzow MR, Price-Troska T, Henderson KJ, Ahmann GJ, Gertz MA. Prognostic value of chromosome 1q21 gain by fluorescent in situ hybridization and increase CKS1B expression in myeloma. Leukemia 2006 Nov; 20(11):2034-40. Epub 2006 Oct 05.
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  45. Landstrom AP, Ketterling RP, Knudson RA, Tefferi A. Utility of peripheral blood dual color, double fusion fluorescent in situ hybridization for BCR/ABL fusion to assess cytogenetic remission status in chronic myeloid leukemia. Leuk Lymphoma 2006 Oct; 47(10):2055-61.
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  46. Einerson RR, Law ME, Blair HE, Kurtin PJ, McClure RF, Ketterling RP, Flynn HC, Dogan A, Remstein ED. Novel FISH probes designed to detect IGK-MYC and IGL-MYC rearrangements in B-cell lineage malignancy identify a new breakpoint cluster region designated BVR2. Leukemia 2006 Oct; 20(10):1790-9. Epub 2006 Aug 03.
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  47. Tefferi A, Cortes J, Verstovsek S, Mesa RA, Thomas D, Lasho TL, Hogan WJ, Litzow MR, Allred JB, Jones D, Byrne C, Zeldis JB, Ketterling RP, McClure RF, Giles F, Kantarjian HM. Lenalidomide therapy in myelofibrosis with myeloid metaplasia. Blood 2006 Aug 15; 108(4):1158-64. Epub 2006 Apr 11.
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  48. Pardanani A, Ketterling RP, Li CY, Patnaik MM, Wolanskyj AP, Elliott MA, Camoriano JK, Butterfield JH, Dewald GW, Tefferi A. FIP1L1-PDGFRA in eosinophilic disorders: prevalence in routine clinical practice, long-term experience with imatinib therapy, and a critical review of the literature. Leuk Res 2006 Aug; 30(8):965-70. Epub 2006 Jan 06.
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  49. Mensink KA, Ketterling RP, Flynn HC, Knudson RA, Lindor NM, Heese BA, Spinner RJ, Babovic-Vuksanovic D. Connective tissue dysplasia in five new patients with NF1 microdeletions: further expansion of phenotype and review of the literature - art. no. e8. J Med Genet 2006 Feb; 43(2):E8.
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  50. Soma LA, Gollin SM, Remstein ED, Ketterling RP, Flynn HC, Rajasenan KK, Swerdlow SH. Splenic small B-cell lymphoma with IGH/BCL3 translocation. Hum Pathol 2006 Feb; 37(2):218-30.
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  51. Wiktor AE, Van Dyke DL, Stupca PJ, Ketterling RP, Thorland EC, Shearer BM, Fink SR, Stockero KJ, Majorowicz JR, Dewald GW. Preclinical validation of fluorescence in situ hybridization assays for clinical practice. Genet Med 2006 Jan; 8(1):16-23.
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  52. Perry CG, Young WF Jr, McWhinney SR, Bei T, Stergiopoulos S, Knudson RA, Ketterling RP, Eng C, Stratakis CA, Carney JA. Functioning paraganglioma and gastrointestinal stromal tumor of the jejunum in three women: syndrome or coincidence. Am J Surg Pathol 2006 Jan; 30(1):42-9.
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  53. Dewald GW, Therneau T, Larson D, Lee YK, Fink S, Smoley S, Paternoster S, Adeyinka A, Ketterling R, Van Dyke DL, Fonseca R, Kyle R. Relationship of patient survival and chromosome anomalies detected in metaphase and/or interphase cells at diagnosis of myeloma. Blood 2005 Nov 15; 106(10):3553-8.
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  54. Lewis JT, Ketterling RP, Halling KC, Reynolds C, Jenkins RB, Visscher DW. Analysis of intratumoral heterogeneity and amplification status in breast carcinomas with equivocal (2+) HER-2 immunostaining. Am J Clin Pathol 2005 Aug; 124(2):273-81.
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  55. Shearer BM, Flynn HC, Knudson RA, Ketterling RP. Interphase FISH to detect PBX1/E2A fusion resulting from the der(19)t(1;19)(q23;p13.3) or t(1;19)(q23;p13.3) in paediatric patients with acute lymphoblastic leukaemia. Br J Haematol 2005 Apr; 129(1):45-52.
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  56. Qian X, Jin L, Shearer BM, Ketterling RP, Jalal SM, Lloyd RV. Molecular diagnosis of Ewing's sarcoma/primitive neuroectodermal tumor in formalin-fixed paraffin-embedded tissues by RT-PCR and fluorescence in situ hybridization. Diagn Mol Pathol 2005 Mar; 14(1):23-8.
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  57. Mesa RA, Li CY, Kettering RP, Schroeder GS, Knudson RA, Tefferi A. Leukemic transformation in myelofibrosis with myeloid metaplasia: a single-institution experience with 91 cases. Blood 2005 Feb 1; 105(3):973-7.
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  58. Mesa RA, Li CY, Ketterling RP, Schroeder GS, Knudson RA, Tedderi A. Leukemic transformation in myelofibrosis with myeloid metaplasia: a single-institution experience with 91 cases. Blood 1 2005 Feb 1; 105(3):973-7.
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  59. Shearer BM, Knudson RA, Flynn HC, Ketterling RP. Development of a D-FISH method to detect DEK/CAN fusion resulting from t(6;9)(p23;q34) in patients with acute myelogenous leukemia. Leukemia 2005 Jan; 19(1):126-31.
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  60. Pardanani A, Brockman SR, Paternoster SF, Flynn HC, Ketterling RP, Lasho TL, Ho CL, Li CY, Dewald GW, Tefferi A. FIP1L1-PDGFRA fusion: prevalence and clinicopathologic correlates in 89 consecutive patients with moderate to severe eosinophilia. Blood 2004 Nov 15; 104(10):3038-45.
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  61. Adeyinka A, Stockero KJ, Flynn HC, Lorentz CP, Ketterling RP, Jalal SM. Familial 22q11.2 deletions in DiGeorge/velocardiofacial syndrome are predominantly smaller than the commonly observed 3Mb. Genet Med 2004 Nov-Dec; 6(6):517-20.
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  62. Chen YC, Chou JM, Ketterling RP, Letendre L, Li CY. Histologic and immunohistochemical study of bone marrow monocytic nodules in 21 cases with myelodysplasia. Am J Clin Pathol 2003 Dec; 120(6):874-81.
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  63. Pardanani A, Ketterling RP, Brockman SR, Flynn HC, Paternoster SF, Shearer BM, Reeder TL, Li CY, Cross NCP, Cools J, Gilliland DG, Dewald GW, Tefferi A. CHIC2 deletion, a surrogate for FIP1L1-PDGFRA fusion, occurs in systemic mastocytosis associated with eosinophilia and predicts response to imatinib mesylate therapy. Blood 2003 Nov 1; 102(9):3093-6.
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  64. Ensenauer RE, Adeyinka A, Flynn HC, Michels VV, Lindor NM, Dawson DB, Thorland EC, Lorentz CP, Goldstein JL, McDonald MT, Smith WE, Simon-Fayard E, Alexander AA, Kulharya AS, Ketterling RP, Clark RD, Jalal SM. Microduplication 22q11.2, an emerging syndrome: Clinical, cytogenetic, and molecular analysis of thirteen patients. Am J Hum Genet 2003 Nov; 73(5):1027-40.
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  65. Brockman SR, Paternoster SF, Ketterling RP, Dewald GW. New highly sensitive fluorescence in situ hybridization method to detect PML/RARA fusion in acute promyelocytic leukemia. Cancer Genetics & Cytogenetics 2003 Sep; 145(2):144-51.
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  66. Jalal SM, Harwood AR, Sekhon GS, Lorentz CP, Ketterling RP, Babovic-Vuksanovic D, Meyer RG, Ensenauer R, Anderson MH, Michels VV. Utility of subtelomeric fluorescent DNA probes for detection of chromosome anomalies in 425 patients. Genet Med 2003 Jan-Feb; 5(1):28-34.
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  67. Ketterling RP, Wyatt WA, VanWier SA, Law M, Hodnefield JM, Hanson CA, Dewald GW. Primary myelodysplastic syndrome with normal cytogenetics: utility of 'FISH panel testing' and M-FISH. Leuk Res 2002 Mar; 26(3):235-40.
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  68. Hand JL, Michels VV, Marinello MJ, Ketterling RP, Jalal SM. Inherited interstitial deletion of chromosomes 5p and 16q without apparent phenotypic effect: further confirmation. Prenat Diagn 2000 Feb; 20(2):144-8; discussion 149-51.
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  69. Ketterling RP, Vielhaber E, Li X, Drost J, Schaid DJ, Kasper CK, Phillips JA 3rd, Koerper MA, Kim H, Sexauer C, Gruppo R, Ambriz R, Paredes R, Sommer SS. Germline origins in the human F9 gene: frequent G:C-->A:T mosaicism and increased mutations with advanced maternal age. Hum Genet 1999 Dec; 105(6):629-40.
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  70. Heit JA, Ketterling RP, Zapata RE, Ordonez SM, Kasper CK, Sommer SS. Haemophilia B Brandenberg-type promoter mutation. Haemophilia 1999 Jan; 5(1):73-5.
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  71. Ketterling RP, Drost JB, Scaringe WA, Liao DZ, Liu JZ, Kasper CK, Sommer SS. Reported in vivo splice-site mutations in the factor IX gene: severity of splicing defects and a hypothesis for predicting deleterious splice donor mutations. Hum Mutat 1999; 13(3):221-31.
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  72. Ketterling RP, Tazelaar HD. Kaposi's Sarcoma of the Lung. College of American Pathology Performance Improvement Program, Cycle-D, 1998.
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  73. Heit JA, Thorland EC, Ketterling RP, Lind TJ, Daniels TM, Zapata RE, Ordonez SM, Kasper CK, Sommer SS. Germline mutations in Peruvian patients with hemophilia B: pattern of mutation in AmerIndians is similar to the putative endogenous germline pattern. Hum Mutat 1998; 11(5):372-6.
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  74. Knoll A, Ketterling RP, Sommer SS. Absence of somatic mosaicism in 17 families with hemophilia B: an analysis with a sensitivity 10- to 1000-fold greater than that of sequencing gels. Hum Genet 1996 Nov; 98(5):539-45.
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  75. Sommer SS, Ketterling RP. The factor IX gene as a model for analysis of human germline mutations: an update. Hum Mol Genet 1996; 5(Spec No):1505-14.
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  76. Thorland EC, Weinshenker BG, Liu JZ, Ketterling RP, Vielhaber EL, Kasper CK, Ambriz R, Paredes R, Sommer SS. Molecular epidemiology of factor IX germline mutations in Mexican Hispanics: pattern of mutation and potential founder effects. Thrombosis & Haemostasis 1995 Dec; 74(6):1416-22.
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  77. Sommer SS, Knoll A, Greenberg CR, Ketterling RP. Germline mosaicism in a female who seemed to be a carrier by sequence analysis. Hum Mol Genet 1995 Nov; 4(11):2181-2.
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  78. Antonarakis SE, Rossiter JP, Young M, Horst J, de Moerloose P, Sommer SS, Ketterling RP, Kazazian HH Jr, Negrier C, Vinciguerra C. Factor VIII gene inversions in severe hemophilia A: results of an international consortium study. Blood 1995 Sep 15; 86(6):2206-12.
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  79. Ketterling RP, Liu JZ, Liao D, Kasper CK, Ambriz R, Paredes R, Sommer SS. Two novel factor IX promoter mutations: incremental progress towards 'saturation in vivo mutagenesis' of a human promoter region. Hum Mol Genet 1995 Apr; 4(4):769-70.
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  80. Antonarakis SE, Rossiter JP, Young M, Horst J, de Moerloose P, Sommer SS, Ketterling RP, Kazazian HH Jr, et al. Factor VIII gene inversions in severe Hemophilia A: Results of an international consortium study. Blood 1995; 86:2206-12.
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  81. Rossiter JP, Young M, Kimberland ML, Hutter P, Ketterling RP, Gitschier J, Horst J, Morris MA, Schaid DJ, de Moerloose P. Factor VIII gene inversions causing severe hemophilia A originate almost exclusively in male germ cells. Hum Mol Genet 1994 Jul; 3(7):1035-9.
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  82. Sommer SS, Ketterling RP. How precisely can data from transgenic mouse mutation-detection systems be extrapolated to humans--lessons from the human factor IX gene. Mutat Res 1994 Jun 1; 307:517-531.
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  83. Ketterling RP, Vielhaber E, Sommer SS. The rates of C-C-(T-A and G-C-)C-G transversions at CpG dinucleotides in the human factor IX gene. Am J Hum Genet 1994 May; 54:831-835.
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  84. Sommer SS, Tillotson VL, Vielhaber EL, Ketterling RP, Dutton CM. "Cryptic" dinucleotide polymorphism in the 3' region of the factor IX gene shows substantial variation among different populations. Hum Genet 1994 Mar; 93(3):357-8.
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  85. Ketterling RP, Vielhaber EL, Lind TJ, Thorland EC, Sommer SS. The rates and patterns of deletions in the human factor IX gene. Am J Hum Genet 1994 Feb; 54(2):201-13.
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  86. Ketterling RP, Sommer SS. Microdeletions in the factor IX gene: three recurrences associated with a quasipalindromic sequence. Hum Mol Genet 1994 Jan; 3(1):191-2.
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  87. Vielhaber E, Jacobson DP, Ketterling RP, Liu JZ, Sommer SS. A mutation in the 3' untranslated region of the factor IX gene in four families with hemophilia B. Hum Mol Genet 1993 Aug; 2(8):1309-10.
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  88. Bottema CD, Ketterling RP, Vielhaber E, Yoon HS, Gostout B, Jacobson DP, Shapiro A, Sommer SS. The pattern of spontaneous germ-line mutation: relative rates of mutation at or near CpG dinucleotides in the factor IX gene. Hum Genet 1993 Jun; 91(5):496-503.
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  89. Gostout B, Vielhaber E, Ketterling RP, Yoon HS, Bottema CD, Kasper CK, Koerper MA, Sommer SS. Germline mutations in the factor IX gene: a comparison of the pattern in Caucasians and non-Caucasians. Hum Mol Genet 1993 Mar; 2(3):293-8.
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  90. Sommer SS, Ketterling RP. A postulated mechanism for deletions with inversions. Am J Hum Genet 1993; 52:1016-18.
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  91. Ketterling RP, Vielhaber E, Bottema CD, Schaid DJ, Phillips JA, Sexauer C, Kim H, Gruppo R, Sommer SS. Germline origins of mutation in families with hemophilia B: The sex ratio varies with the type of mutation Am J Hum Genet 1993; 52:152-66.
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  92. Ketterling RP, Ricke DO, Wurster MW, Sommer SS. Deletions with inversions: report of a mutation and review of the literature. Hum Mutation 1993; 2:53-7.
  93. Ricke DO, Ketterling RP, Sommer SS. PRE: a novel element with the hallmarks of a retrotransposon derived from an unknown structural RNA. Nucleic Acids Res 1992 Oct 11; 20(19):5233.
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