Publications - Nelson Leung, M.D.

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1. Gertz MA, Leung N, Lacy MQ, Dispenzieri A, Zeldenrust SR, Hayman SR, Buadi FK, Dingli D, Greipp PR, Kumar SK, Lust JA, Rajkumar SV, Russell SJ, Witzig TE. Clinical outcome of immunoglobulin light chain amyloidosis affecting the kidney. Nephrol Dial Transplant 2009 Oct; 24(10):3132-7. Epub 2009 Apr 29.
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2. Lee CU, Wood CM, Hesley GK, Leung N, Bridges MD, Lund JT, Lee PU, Pittelkow MR. Large sample of nephrogenic systemic fibrosis cases from a single institution. Arch Dermatol 2009 Oct; 145(10):1095-102.
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3. Shaikh A, Wiisanen ME, Gunderson HD, Leung N. Acquired fanconi syndrome after treatment with capecitabine, irinotecan, and bevacizumab. Ann Pharmacother 2009 Jul-Aug; 43(7-8):1370-3.
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4. Czarnecki PG, Lager DJ, Leung N, Dispenzieri A, Cosio FG, Fervenza FC. Long-term outcome of kidney transplantation in patients with fibrillary glomerulonephritis or monoclonal gammopathy with fibrillary deposits. Kidney Int 2009 Feb; 75(4):420-7. Epub 2008 Nov 26.
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5. Poshusta TL, Sikkink LA, Leung N, Clark RJ, Dispenzieri A, Ramirez-Alvarado M. Mutations in specific structural regions of immunoglobulin light chains are associated with free light chain levels in patients with AL amyloidosis. PLoS One 2009; 4(4):e5169. Epub 2009 Apr 13.
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6. Leung N, Eirin A, Irazabal MV, Maddox DE, Gunderson HD, Fervenza FC, Garovic VD. Acute kidney injury in patients with inactive cytochrome P450 polymorphisms. Ren Fail 2009; 31(8):749-52.
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7. Soares SM, Fervenza FC, Lager DJ, Gertz MA, Cosio FG, Leung N. Bleeding complications after transcutaneous kidney biopsy in patients with systemic amyloidosis: single-center experience in 101 patients. Am J Kidney Dis 2008 Dec; 52(6):1079-83. Epub 2008 Jul 23.
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8. Fervenza FC, Croatt AJ, Bittar CM, Rosenthal DW, Lager DJ, Leung N, Zeldenrust SR, Nath KA. Induction of heme oxygenase-1 and ferritin in the kidney in warm antibody hemolytic anemia. Am J Kidney Dis 2008 Nov; 52(5):972-7. Epub 2008 Sep 21.
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9. Leung N, Gloor JM, Dean PG, Lacy MQ, Porrata LF, Griffin MD. Acute cellular rejection in a renal allograft immediately following leukocyte engraftment after auto-SCT. Bone Marrow Transplant 2008 Oct 13. [Epub ahead of print]
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10. Gertz MA, Ansell SM, Dingli D, Dispenzieri A, Buadi FK, Elliott MA, Gastineau DA, Hayman SR, Hogan WJ, Inwards DJ, Johnston PB, Kumar S, Lacy MQ, Leung N, Micallef IN, Porrata LF, Schafer BA, Wolf RC, Litzow MR. Autologous stem cell transplant in 716 patients with multiple myeloma: low treatment-related mortality, feasibility of outpatient transplant, and effect of a multidisciplinary quality initiative. Mayo Clin Proc 2008 Oct; 83(10):1131-8.
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11. Pillon L, Sweeting RS, Arora A, Notkin A, Ballard HS, Wieczorek RL, Leung N. Approach to acute renal failure in biopsy proven myeloma cast nephropathy: Is there still a role for plasmapheresis? Kidney Int 2008 Oct; 74(7):956-61.
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12. Shaikh A, Habermann TM, Fidler ME, Kumar S, Leung N. Acute renal failure secondary to severe type I cryoglobulinemia following rituximab therapy for Waldenstrom's macroglobulinemia. Clin Exp Nephrol 2008 Aug; 12(4):292-5. Epub 2008 Feb 22.
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13. Lorenz EC, Gertz MA, Fervenza FC, Dispenzieri A, Lacy MQ, Hayman SR, Gastineau DA, Leung N. Long-term outcome of autologous stem cell transplantation in light chain deposition disease. Nephrol Dial Transplant 2008 Jun; 23(6):2052-7. Epub 2008 Jan 04.
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14. Leung N, Gertz MA, Zeldenrust SR, Rajkumar SV, Dispenzieri A, Fervenza FC, Kumar S, Lacy MQ, Lust JA, Greipp PR, Witzig TE, Hayman SR, Russell SJ, Kyle RA, Winters JL. Improvement of cast nephropathy with plasma exchange depends on the diagnosis and on reduction of serum free light chains. Kidney Int 2008 Jun; 73(11):1282-8. Epub 2008 Apr 02.
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15. Leung N, Gertz MA, Zeldenrust SR, Rajkumar SV, Dispenzieri A, Fervenza FC, Kumar S, Lacy MQ, Lust JA, Greipp PR, Witzig TE, Hayman SR, Russell SJ, Kyle RA, Winters JL. Improvement of cast nephropathy with plasma exchange depends on the diagnosis and on reduction of serum free light chains. Kidney Int 2008 Jun; 73(11):1282-8.
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16. Misra S, Gyamlani G, Swaminathan S, Buehrig CK, Bjarnason H, McKusick MA, Andrews JC, Johnson CM, Fervenza FC, Leung N. Safety and diagnostic yield of transjugular renal biopsy. J Vasc Interv Radiol 2008 Apr; 19(4):546-51.
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17. Kumar S, Dispenzieri A, Lacy MQ, Hayman SR, Leung N, Zeldenrust SR, Buadi FK, Kyle RA, Rajkumar SV, Gertz MA. Serum uric acid: novel prognostic factor in primary systemic amyloidosis. Mayo Clin Proc 2008 Mar; 83(3):297-303.
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18. Fervenza FC, Cosio FG, Erickson SB, Specks U, Herzenberg AM, Dillon JJ, Leung N, Cohen IM, Wochos DN, Bergstralh E, Hladunewich M, Cattran DC. Rituximab treatment of idiopathic membranous nephropathy. Kidney Int 2008 Jan; 73(1):117-25. Epub 2007 Oct 17.
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19. Gertz M, Lacy M, Dispenzieri A, Hayman S, Kumar S, Buadi F, Leung N, Litzow M. Troponin T level as an exclusion criterion for stem cell transplantation in light-chain amyloidosis. Leuk Lymphoma 2008 Jan; 49(1):36-41.
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20. Kaplan B, Ramirez-Alvarado M, Dispenzieri A, Zeldenrust SR, Leung N, Livneh A, Gallo G. Isolation and biochemical characterization of plasma monoclonal free light chains in amyloidosis and multiple myeloma: a pilot study of intact and truncated forms of light chains and their charge properties. Clin Chem Lab Med 2008; 46(3):335-41.
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21. Gertz MA, Lacy MQ, Dispenzieri A, Hayman SR, Kumar SK, Leung N, Gastineau DA. Transplantation without growth factor: engraftment kinetics after stem cell transplantation for primary systemic amyloidosis (AL). Bone Marrow Transplant 2007 Nov; 40(10):989-93. Epub 2007 Sep 10.
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22. Gertz MA, Lacy MQ, Dispenzieri A, Hayman SR, Kumar SK, Leung N, Gastineau DA. Effect of hematologic response on outcome of patients undergoing transplantation for primary amyloidosis: importance of achieving a complete response. Haematologica 2007 Oct; 92(10):1415-8.
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23. Leung N, Rajkumar SV. Renal manifestations of plasma cell disorders. Am J Kidney Dis 2007 Jul; 50(1):155-65.
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24. Shanafelt TD, Lin T, Geyer SM, Zent CS, Leung N, Kabat B, Bowen D, Grever MR, Byrd JC, Kay NE. Pentostatin, cyclophosphamide, and rituximab regimen in older patients with chronic lymphocytic leukemia. Cancer 2007 Jun 1; 109(11):2291-8.
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25. Gera M, Griffin MD, Specks U, Leung N, Stegall MD, Fervenza FC. Recurrence of ANCA-associated vasculitis following renal transplantation in the modern era of immunosupression. Kidney Int 2007 Jun; 71(12):1296-301. Epub 2007 Apr 04.
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26. Leung N, Dispenzieri A, Lacy MQ, Kumar SK, Hayman SR, Fervenza FC, Cha SS, Gertz MA. Severity of baseline proteinuria predicts renal response in immunoglobulin light chain-associated amyloidosis after autologous stem cell transplantation. Clin J Am Soc Nephrol 2007 May; 2(3):440-4. Epub 2007 Apr 04.
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27. Gertz MA, Lacy MQ, Dispenzieri A, Hayman SR, Kumar S, Leung N, Gastineau DA. Impact of age and serum creatinine value on outcome after autologous blood stem cell transplantation for patients with multiple myeloma. Bone Marrow Transplant 2007 May; 39(10):605-11.
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28. Hoyer RJ, Leung N, Witzig TE, Lacy MQ. Treatment of diuretic refractory pleural effusions with bevacizumab in four patients with primary systemic amyloidosis. Am J Hematol 2007 May; 82(5):409-13.
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29. Swaminathan S, Leung N. Nephrogenic fibrosing dermopathy: lessons from the past. Int J Dermatol 2006 Jun; 45(6):639-41.
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30. Swaminathan S, Leung N, Lager DJ, Melton LJ 3rd, Bergstralh EJ, Rohlinger A, Fervenza FC. Changing incidence of glomerular disease in Olmsted County, Minnesota: a 30-year renal biopsy study. Clin J Am Soc Nephrol 2006 May; 1(3):483-7. Epub 2006 Apr 19.
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31. Soares SM, Lager DJ, Leung N, Haugen EN, Fervenza FC. A proliferative glomerulonephritis secondary to a monoclonal IgA. Am J Kidney Dis 2006 Feb; 47(2):342-9.
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32. Leung N, Leung TR, Cha SS, Dispenzieri A, Lacy MQ, Gertz MA. Excessive fluid accumulation during stem cell mobilization: a novel prognostic factor of first-year survival after stem cell transplantation in AL amyloidosis patients. Blood 2005 Nov 15; 106(10):3353-7.
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33. Gertz MA, Leung N, Lacy MQ, Dispenzieri A. Myeloablative chemotherapy and stem cell transplantation in myeloma or primary amyloidosis with renal involvement. Kidney Int 2005 Oct; 68(4):1464-71.
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34. Leung N, Dispenzieri A, Fervenza FC, Lacy MQ, Villicana R, Cavalcante JL, Gertz MA. Renal response after high-dose melphalan and stem cell transplantation is a favorable marker in patients with primary systemic amyloidosis. Am J Kidney Dis 2005 Aug; 46(2):270-7.
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35. Leung N, Griffin MD, Dispenzieri A, Haugen EN, Gloor JM, Schwab TR, Textor SC, Lacy MQ, Litzow MR, Cosio FG, Larson TS, Gertz MA, Stegall MD. Living donor kidney and autologous stem cell transplantation for primary systemic amyloidosis (AL) with predominant renal involvement. Am J Transplant 2005 Jul; 5(7):1660-70.
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36. Borza DB, Chedid MF, Colon S, Lager DJ, Leung N, Fervenza FC. Recurrent Goodpasture's disease secondary to a monoclonal IgA1-kappa antibody autoreactive with the alpha 1/alpha 2 chains of type IV collagen. Am J Kidney Dis 2005 Feb; 45(2):397-406.
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37. Leung N, Slezak JM, Bergstralh EJ, Dispenzieri A, Lacy MQ, Wolf RC, Gertz MA. Acute renal insufficiency after high-dose melphalan in patients with primary systemic amyloidosis during stem cell transplantation. Am J Kidney Dis 2005 Jan; 45(1):102-11.
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38. de la Vega LP, Fervenza FC, Lager D, Habermann T, Leung N. Acute granulomatous interstitial nephritis secondary to bisphosphonate alendronate sodium. Ren Fail 2005; 27(4):485-9.
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39. Rosenthal D, Lien YHH, Lager D, Lai LW, Shang SH, Leung N, Fervenza FC. A novel a-galactosidase a mutant (M42L) identified in a renal variant of Fabry disease - art. no. E85. Am J Kidney Dis 2004 Nov; 44(5):E85.
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40. Leung N, Ytterberg SR, Blute ML, Lager DJ, Specks U, Fervenza FC. Wegener's granulomatosis presenting as multiple bilateral renal masses. Nephrol Dial Transplant 2004 Apr; 19(4):984-7.
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41. Leung N, Lager DJ, Gertz MA, Wilson K, Kanakiriya S, Fervenza FC. Long-term outcome of renal transplantation in light-chain deposition disease. Am J Kidney Dis 2004 Jan; 43(1):147-53.
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42. Cohen AJ, Stegall MD, Rosen CB, Wiesner RH, Leung N, Kremers WK, Zein NN. Chronic renal dysfunction late after liver transplantation. Liver Transpl 2002 Oct; 8(10):916-21.
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43. Leung N. A tale of two markers. Liver Transpl 2002 Jul; 8(7):600-2.
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44. Leung N, Croatt AJ, Haggard JJ, Grande JP, Nath KA. Acute cholestatic liver disease protects against glycerol-induced acute renal failure in the rat. Kidney Int 2001 Sep; 60(3):1047-57.
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45. Leung N, O'Brien T, McMahon M. Case report: Parenteral feeding in a patient with hypertriglyceridemia and elevated liver enzyme levels. Endocr Prac 1999; 5:194-7.
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