Publications - Christopher P. Appleton, M.D.

Back to research profile

  1. Kansal MM, Lester SJ, Surapaneni P, Sengupta PP, Appleton CP, Ommen SR, Ressler SW, Hurst RT. Usefulness of two-dimensional and speckle tracking echocardiography in "Gray Zone" left ventricular hypertrophy to differentiate professional football player's heart from hypertrophic cardiomyopathy. Am J Cardiol. 2011 Nov 1; 108(9):1322-6. Epub 2011 Aug 18.
    View PubMed
  2. Eleid MF, Appleton CP, Lopez AG, Cha S, Hurst RT. Coronary artery plaque burden does not affect left ventricular diastolic function in asymptomatic adults with normal ejection fraction. J Am Soc Echocardiogr. 2011 Aug; 24(8):909-14. Epub 2011 May 06.
    View PubMed
  3. Mookadam F, Warsame TA, Yang HS, Emani UR, Appleton CP, Raslan SF. Effect of positional changes on inferior vena cava size. Eur J Echocardiogr. 2011 Apr; 12(4):322-5. Epub 2011 Mar 16.
    View PubMed
  4. Alharthi MS, Calleja A, Panse P, Appleton C, Jaroszewski DE, Tazelaar HD, Mookadam F. Multimodality imaging showing complete cardiovascular involvement by Erdheim-Chester disease. Eur J Echocardiogr. 2010 Aug; 11(7):E25. Epub 2010 Apr 20.
    View PubMed
  5. Eleid MF, Lester SJ, Wiedenbeck TL, Patel SD, Appleton CP, Nelson MR, Humphries J, Hurst RT. Carotid ultrasound identifies high risk subclinical atherosclerosis in adults with low framingham risk scores. J Am Soc Echocardiogr. 2010 Aug; 23(8):802-8. Epub 2010 Jun 29.
    View PubMed
  6. Eleid MF, Hurst RT, Vargas HE, Rakela J, Mulligan DC, Appleton CP. Short-term cardiac and noncardiac mortality following liver transplantation. J Transplant. 2010; 2010. Epub 2010 Aug 12.
    View PubMed
  7. Vianna-Pinton R, Moreno CA, Baxter CM, Lee KS, Tsang TS, Appleton CP. Two-dimensional speckle-tracking echocardiography of the left atrium: feasibility and regional contraction and relaxation differences in normal subjects. J Am Soc Echocardiogr. 2009 Mar; 22(3):299-305.
    View PubMed
  8. Nagueh SF, Appleton CP, Gillebert TC, Marino PN, Oh JK, Smiseth OA, Waggoner AD, Flachskampf FA, Pellikka PA, Evangelisa A. Recommendations for the evaluation of left ventricular diastolic function by echocardiography. Eur J Echocardiogr. 2009 Mar; 10(2):165-93.
    View PubMed
  9. Nagueh SF, Appleton CP, Gillebert TC, Marino PN, Oh JK, Smiseth OA, Waggoner AD, Flachskampf FA, Pellikka PA, Evangelista A. Recommendations for the evaluation of left ventricular diastolic function by echocardiography. J Am Soc Echocardiogr. 2009 Feb; 22(2):107-33.
    View PubMed
  10. Al-Omari MA, Finstuen J, Appleton CP, Barnes ME, Tsang TS. Echocardiographic assessment of left ventricular diastolic function and filling pressure in atrial fibrillation. Am J Cardiol. 2008 Jun 15; 101(12):1759-65.
    View PubMed
  11. Umphrey LG, Hurst RT, Eleid MF, Lee KS, Reuss CS, Hentz JG, Vargas HE, Appleton CP. Preoperative dobutamine stress echocardiographic findings and subsequent short-term adverse cardiac events after orthotopic liver transplantation. Liver Transpl. 2008 Jun; 14(6):886-92.
    View PubMed
  12. Lee KS, Appleton CP, Lester SJ, Adam TJ, Hurst RT, Moreno CA, Altemose GT. Relation of electrocardiographic criteria for left atrial enlargement to two-dimensional echocardiographic left atrial volume measurements. Am J Cardiol. 2007 Jan 1; 99(1):113-8.
    View PubMed
  13. Eleid MF, Hsu PY, Appleton CP, Collins JM. Peripheral bronchial carcinoid tumor presenting as a right cardiophrenic angle mass. Radiology Case Reports (on-line) 2007; 2(3).
  14. Little WC, Zile MR, Klein A, Appleton CP, Kitzman DW, Wesley-Farrington DJ. Effect of losartan and hydrochlorothiazide on exercise tolerance in exertional hypertension and left ventricular diastolic dysfunction. Am J Cardiol. 2006 Aug 1; 98(3):383-5. Epub 2006 Jun 12.
    View PubMed
  15. Hurst T, Olson TH, Olson LE, Appleton CP. Cardiac syndrome X and endothelial dysfunction: new concepts in prognosis and treatment. Am J Med. 2006 Jul; 119(7):560-6.
    View PubMed
  16. Abhayaratna WP, Seward JB, Appleton CP, Douglas PS, Oh JK, Tajik AJ, Tsang TS. Left atrial size: physiologic determinants and clinical applications. J Am Coll Cardiol. 2006 Jun 20; 47(12):2357-63.
    View PubMed
  17. Reuss CS, Moreno CA, Appleton CP, Lester SJ. Doppler tissue imaging during supine and upright exercise in healthy adults. J Am Soc Echocardiogr. 2005 Dec; 18(12):1343-8.
    View PubMed
  18. Takemoto Y, Barnes ME, Seward JB, Lester SJ, Appleton CA, Gersh BJ, Bailey KR, Tsang TSM. Usefulness of left atrial volume in predicting first congestive heart failure in patients >= 65 years of age with well-preserved left ventricular systolic function. American Journal of Cardiology. 2005 Sep 15; 96(6):832-6.
    View PubMed
  19. Norager B, Husic M, Moller JE, Pellikka PA, Appleton CP, Egstrup K. The Doppler myocardial performance index during low-dose dobutamine echocardiography predicts mortality-and left ventricular dilation after a first acute myocardial infarction. Am Heart J. 2005 Sep; 150(3):522-9.
    View PubMed
  20. Grayburn PA, Appleton CP, DeMaria AN, Greenberg B, Lowes B, Oh J, Plehn JF, Rahko P, Sutton MS, Eichhorn EJ. Echocardiographic predictors of morbidity and mortality in patients with advanced heart failure - The beta-blocker evaluation of survival trial (BEST). J Am Coll Cardiol. 2005 Apr 5; 45(7):1064-71.
    View PubMed
  21. Abbas AE, Appleton CP, Liu PT, Sweeney JP. Congenital absence of the pericardium: case presentation and review of literature. Int J Cardiol. 2005 Jan; 98(1):21-5.
    View PubMed
  22. Srivathsan K, Lester SJ, Appleton CP, Scott LR, Munger TM. Ventricular tachycardia in the absence of structural heart disease. Indian Pacing Electrophysiol J. 2005; 5(2):106-21. Epub 2005 Apr 01.
    View PubMed
  23. Abbas A, Lester S, Moreno FC, Srivathsan K, Fortuin D, Appleton C. Noninvasive assessment of right atrial pressure using Doppler tissue imaging. J Am Soc Echocardiogr. 2004 Nov; 17(11):1155-60.
    View PubMed
  24. Abbas AE, Fortuin FD, Schiller NB, Appleton CP, Moreno CA, Lester SJ. Echocardiographic determination of mean pulmonary artery pressure. Am J Cardiol. 2003 Dec 1; 92(11):1373-6.
    View PubMed
  25. Srivathsan K, Byrne RA, Appleton CP, Scott LRP. Pneumopericardium and pneumothorax contralateral to venous access site after permanent pacemaker implantation. Europace. 2003 Oct; 5(4):361-3.
    View PubMed
  26. Moller JE, Poulsen SH, Sondergaard E, Seward JB, Appleton CP, Egstrup K. Impact of early changes in left ventricular filling pattern on long-term outcome after acute myocardial infarction. Int J Cardiol. 2003 Jun; 89(2-3):207-15.
    View PubMed
  27. Abbas AE, Fortuin FD, Schiller NB, Appleton CP, Moreno CA, Lester SJ. A simple method for noninvasive estimation of pulmonary vascular resistance. J Am Coll Cardiol. 2003 Mar 19; 41(6):1021-7.
    View PubMed
  28. Lindenfeld J, Ghali JK, Krause-Steinrauf HJ, Khan S, Adams K, Goldman S, Peberedy MA, Yancy C, Thaneemit-Chen S, Larsen RL, Young J, Lowes B, Rosenberg YD, BEST Investigators. Hormone replacement therapy is associated with improved survival in women with advanced heart failure. J Am Coll Cardiol. 2003; 423(7):1238-45.
  29. Tsang TSM, Gersh BJ, Appleton CP, Tajik AJ, Barnes ME, Bailey KR, Oh JK, Leibson C, Montgomery SC, Seward JB. Left ventricular diastolic dysfunction as a predictor of the first diagnosed nonvalvular atrial fibrillation in 840 elderly men and women. J Am Coll Cardiol. 2002 Nov 6; 40(9):1636-44.
    View PubMed
  30. Abbas AE, Loftis R, Lester SJ, Crawford MB, Appleton CP. Generalized tetany: An unusual complication during dobutamine stress echocardiography. J Am Soc Echocardiogr. 2002 Nov; 15(11):1414-6.
    View PubMed
  31. Chaliki HP, Hurrell DG, Nishimura RA, Reinke RA, Appleton CP. Pulmonary venous pressure: Relationship to pulmonary artery, pulmonary wedge, and left atrial pressure in normal, lightly sedated dogs. Catheter Cardiovasc Interv. 2002 Jul; 56(3):432-8.
    View PubMed
  32. Moller JE, Sondergaard E, Poulsen SH, Seward JB, Appleton CP, Egstrup K. Color M-mode and pulsed wave tissue Doppler echocardiography: powerful predictors of cardiac events after first myocardial infarction. J Am Soc Echocardiogr. 2001 Aug; 14(8):757-63.
    View PubMed
  33. Moller JE, Sondergaard E, Poulsen SH, Appleton CP, Egstrup K. Serial Doppler echocardiographic assessment of left and right ventricular performance after a first myocardial infarction. J Am Soc Echocardiogr. 2001 Apr; 14(4):249-55.
    View PubMed
  34. Weyman AE, Butler A, Subhiyah R, Appleton C, Geiser E, Goldstein SA, King ME, Kaul S, Labovitz A, Picard M, Ryan T, Shanewise J. Concept, development, administration, and analysis of a certifying examination in echocardiography for physicians. J Am Soc Echocardiogr. 2001 Feb; 14(2):158-68.
    View PubMed
  35. Ommen SR, Nishimura RA, Appleton CP, Miller FA, Oh JK, Redfield MM, Tajik AJ. Clinical utility of Doppler echocardiography and tissue Doppler imaging in the estimation of left ventricular filling pressures: A comparative simultaneous Doppler-catheterization study. Circulation. 2000 Oct 10; 102(15):1788-94.
    View PubMed
  36. Appleton CP, Firstenberg MS, Garcia MJ, Thomas JD. The echo-Doppler evaluation of left ventricular diastolic function. A current perspective. Cardiol Clin. 2000 Aug; 18(3):513-46, ix.
    View PubMed
  37. Moller JE, Sondergaard E, Seward JB, Appleton CP, Egstrup K. Ratio of left ventricular peak E-wave velocity to flow propagation velocity assessed by color M-mode Doppler echocardiography in first myocardial infarction: prognostic and clinical implications. J Am Coll Cardiol. 2000 Feb; 35(2):363-70.
    View PubMed
  38. Boonyaratavej S, Oh JK, Tajik AJ, Appleton CP, Seward JB. Comparison of mitral inflow and superior vena cava Doppler velocities in chronic obstructive pulmonary disease and constrictive pericarditis. J Am Coll Cardiol. 1998 Dec; 32(7):2043-8.
    View PubMed
  39. Klein AL, Abdalla I, Murray RD, Lee JC, Vandervoort P, Thomas JD, Appleton CP, Tajik AJ. Age independence of the difference in duration of pulmonary venous atrial reversal flow and transmitral A-wave flow in normal subjects. J Am Soc Echocardiogr. 1998 May; 11(5):458-65.
    View PubMed
  40. Yamamoto K, Nishimura RA, Chaliki HP, Appleton CP, Holmes DR Jr, Redfield MM. Determination of left ventricular filling pressure by Doppler echocardiography in patients with coronary artery disease: critical role of left ventricular systolic function. J Am Coll Cardiol. 1997 Dec; 30(7):1819-26.
    View PubMed
  41. Appleton CP. Hemodynamic determinants of Doppler pulmonary venous flow velocity components: new insights from studies in lightly sedated normal dogs. J Am Coll Cardiol. 1997 Nov 15; 30(6):1562-74.
    View PubMed
  42. Hurrell DG, Nishimura RA, Ilstrup DM, Appleton CP. Utility of preload alteration in assessment of left ventricular filling pressure by Doppler echocardiography: a simultaneous catheterization and Doppler echocardiographic study. J Am Coll Cardiol. 1997 Aug; 30(2):459-67.
    View PubMed
  43. Oh JK, Appleton CP, Hatle LK, Nishimura RA, Seward JB, Tajik AJ. The noninvasive assessment of left ventricular diastolic function with two-dimensional and Doppler echocardiography. J Am Soc Echocardiogr. 1997 Apr; 10(3):246-70.
    View PubMed
  44. Appleton CP, Jensen JL, Hatle LK, Oh JK. Doppler evaluation of left and right ventricular diastolic function: a technical guide for obtaining optimal flow velocity recordings. J Am Soc Echocardiogr. 1997 Apr; 10(3):271-92.
    View PubMed
  45. Oh JK, Tajik AJ, Appleton CP, Hatle LK, Nishimura RA, Seward JB. Preload reduction to unmask the characteristic Doppler features of constrictive pericarditis. A new observation. Circulation. 1997 Feb 18; 95(4):796-9.
    View PubMed
  46. Jensen JL, Williams FE, Beilby BJ, Johnson BL, Miller LK, Ginter TL, Tomaselli-Martin G, Appleton CP. Feasibility of obtaining pulmonary venous flow velocity in cardiac patients using transthoracic pulsed wave Doppler technique. J Am Soc Echocardiogr. 1997 Jan-Feb; 10(1):60-6.
    View PubMed
  47. Nishimura RA, Appleton CP, Redfield MM, Ilstrup DM, Holmes DR Jr, Tajik AJ. Noninvasive doppler echocardiographic evaluation of left ventricular filling pressures in patients with cardiomyopathies: a simultaneous Doppler echocardiographic and cardiac catheterization study. J Am Coll Cardiol. 1996 Nov 1; 28(5):1226-33.
    View PubMed
  48. The Stroke Prevention in Atrial Fibrillation Investigators. Adjusted-dose warfarin versus low-intensity, fixed-dose warfarin plus aspirin for high-risk patients with atrial fibrillation: Stroke Prevention in Atrial Fibrillation III randomised clinical trial. Lancet. 1996 Sep 7; 348(9028):633-8.
    View PubMed
  49. Klodas E, Nishimura RA, Appleton CP, Redfield MM, Oh JK. Doppler evaluation of patients with constrictive pericarditis: use of tricuspid regurgitation velocity curves to determine enhanced ventricular interaction. J Am Coll Cardiol. 1996 Sep; 28(3):652-7.
    View PubMed
  50. Hurrell DG, Nishimura RA, Higano ST, Appleton CP, Danielson GK, Holmes DR Jr, Tajik AJ. Value of dynamic respiratory changes in left and right ventricular pressures for the diagnosis of constrictive pericarditis. Circulation. 1996 Jun 1; 93(11):2007-13.
    View PubMed
  51. Rakowski H, Appleton CP, Chan K-L, Dumesnil JG, Honos G, Jue J, Koilpillai C, Lepage S, Martin RP, Mercier L-M, O'Kelley B, Prieur T, Sanfillipo A, Sasson Z, Alvarez N, Pruitt R, Thompson C, Tomlinson C. Recommendations for the measurement and reporting of diastolic function by echocardiography. J Am Soc Echocardiogr. 1996; 9:736-60.
    View PubMed
  52. deFilippi CR, Willett DL, Brickner ME, Appleton CP, Yancy CW, Eichhorn EJ, Grayburn PA. Usefulness of dobutamine echocardiography in distinguishing severe from nonsevere valvular aortic stenosis in patients with depressed left ventricular function and low transvalvular gradients. Am J Cardiol. 1995 Jan 15; 75(2):191-4.
    View PubMed
  53. McBride R, Chesebro JH, Wiebers DO, Holland AE, Linker S, Bardsley WT, Kopecky SL, Litin SC, Meissner I, Zerbe DM, Flaker GC, Webel R, Nolte B, Stevenson P, Byer J, Jenkins JS, Wright W, Anderson DC, Asinger RW, et al. Warfarin versus aspirin for prevention of thromboembolism in atrial fibrillation--stroke prevention in atrial fibrillation II study. Lancet. 1994 Mar 19; 343:687-691.
    View PubMed
  54. Appleton CP, Gonzalez MS, Basnight MA. Relation of left atrial pressure and pulmonary venous flow velocities: importance of baseline mitral and pulmonary venous flow patterns studied in lightly sedated dogs. J Am Soc Echocardiography. 1994; 7:264-75.
  55. Toporoff B, Rosado LJ, Appleton CP, Sethi GK, Copeland JG. Successful treatment of early infective endocarditis and mediastinitus in a heart transplant recipient. J Heart Lung Transplant. 1994; 13:546-8.
    View PubMed
  56. Appleton CP, Galloway JM, Gonzalez MS, Gaballa, M, Basnight MA. Estimation of left ventricular filling pressures using two-dimensional and Doppler echocardiography in adult cardiac patients: additional value of analyzing left atrial size, left atrial ejection fraction and the difference in the duration of pulmonary ve nous and mitral flow velocities at atrial contraction. J Am Coll Cardiol. 1993; 22:1972-82.
    View PubMed
  57. The Stroke Prevention in Atrial Fibrillation Investigators. Predictors of thromboembolism in atrial fibrillation: II. Echocardiographic features of patients at risk. Ann Intern Med. 1992 Jan 1; 116(1):6-12.
    View PubMed
  58. Appleton CP, Hatle LK. The natural history of left ventricular filling abnormalities: assessment by two-dimensional and Doppler echocardiography. Echocardiography. 1992; 9:1-21.
    View PubMed
  59. SPAF Investigators. Clinical predictors of thromboembolism in atrial fibrillation: I. Clinical features of patients at risk The stroke prevention in atrial fibrillation study (SPAF) Ann Internal Med. 1992; 116:1-5.
  60. The Stroke Prevention in Atrial Fibrillation Investigators. Stroke Prevention in Atrial Fibrillation Study. Final results. Circulation. 1991 Aug; 84(2):527-39.
    View PubMed
  61. Appleton CP. Influence of incremental changes in heart rate on mitral flow velocity: assessment in lightly sedated dogs. J Am Coll Cardiol (with accompanying editorial) 1991; 17:227-36.
  62. Gonzalez MS, Basnight MA, Appleton CP. Experimental pericardial effusion: relation of abnormal respiratory variation in mitral flow velocity to hemodynamics and right heart collapse. J Am Coll Cardiol (with accompanying editorial) 1991; 17:239-48.
  63. Gonzalez MS, Basnight MA, Appleton CP. Experimental cardiac tamponade: A hemodynamic and Doppler echocardiographic reexamination of the relation of right and left heart ejection dynamics to the phase of respiration. J Am Coll Cardiol. 1991; 18:243-52.
    View PubMed
  64. Pennock GD, Dalton WS, Roeske WR, Appleton CP, Ryschon KL, Plezia P, Miller TP, Salmon SE. Systemic toxicities associated with high dose verapamil infusion and chemotherapy administration. J National Cancer Inst. 1991; 83:105-10.
  65. Reynolds T, Szymanski K, Langenfeld K, Appleton CP. Visualization of the hepatic veins: new approaches for the echocardiographer. J Am Soc Echocardiography. 1991; 4:93-6.
  66. Appleton CP, Basnight MA, Gonzalez MS. Diastolic mitral regurgitation with atrioventricular conduction abnormalities: relation of mitral flow velocity to transmitral pressure gradients in conscious dogs. J Am Coll Cardiol. 1991; 18:843-9.
    View PubMed
  67. Reynolds T, Appleton CP. Doppler flow velocity patterns of the superior vena cava, hepatic vein, coronary sinus and atrial septal defect: a guide for the echocardiographer. J Am Soc Echocardiography. 1991; 4:503-12.
  68. Basnight MA, Gonzalez MS, Appleton CP. Pulmonary venous flow velocity: relation to hemodynamics, mitral flow velocity and left atrial volume in man. J Am Soc Echocardiography. 1991; 4:547-58.
  69. Ewy GA, Demaria AN, Rogers EW Jr, Skorton DJ, Williams RG, Appleton CP, Feigenbaum H, Tonan JA Jr, Tajik AJ. ACC/AHA guidelines for the clinical application of echocardiography. A report of the American College of Cardiology/American Heart Association Task Force on Assessment of Diagnostic and Therapeutic Cardiovascular Procedures (Subcommittee to Develop Guidel ines for the Clinical Application of Echocardiography). Circulation. 1990 Dec 6; 82:2323-45.
    View PubMed
  70. Chesebro JH, Wiebers DO, Holland AE, Miller DM, Bardsley WT, Litin SC, Zerbe DM, et al. Preliminary report of the stroke prevention in atrial fibrillation study. N Engl J Med. 1990 Mar 22; 322:863-868.
    View PubMed
  71. Appleton CP, Hatle LK, Popp RL. Flow velocity acceleration in the left ventricle: a useful Doppler echocardiographic sign of hemodynamically significant mitral regurgitation. J Am Soc of Echocardiography. 1990; 3:35-45.
  72. Reed KL, Appleton CP, Anderson CF, Shenker L, Sahn DJ. Doppler studies of vena cava flows in human fetuses: insights into normal and abnormal cardiac physiology. Circulation. 1990; 81:498-505.
    View PubMed
  73. Ewy GA, Appleton CP, De Maria AN, Feigenbaum H, Rogers EW, Ronan JA, Skorton DJ, Tajik AJ, Williams RG. Guidelines for the clinical application of echocardiography. J Am Coll Cardiol. 1990; 16:1505-28.
    View PubMed
  74. Reynolds T, Warner MG, Appleton CP. The evaluation of mitral regurgitation: a balanced approach for the cardiac sonographer. J Diagnostic Medical Sonography. 1990; 5:279-85.
  75. Valantine HA, Hatle LK, Appleton CP, Gibbons R, Popp RL. Variability of Doppler echocardiographic indexes of left ventricular filling in transplant recipients and in normal subjects. J Am Soc Echocardiography. 1990; 3:276-84.
  76. The Stroke Prevention in Atrial Fibrillation Investigators. Progress report of the Stroke Prevention in Atrial Fibrillation Study. Stroke. 1990; 21(Suppl III):III-12 -III-17.
  77. The Stroke Prevention in Atrial Fibrillation Investigators. Design of a multicenter randomized trial for the Stroke Prevention in Atrial Fibrillation Study. Stroke. 1990 Apr; 21(4):538-45.
    View PubMed
  78. Valantine HA, Appleton CP, Hatle LK, Hunt SA, Billingham ME, Shumway NE, Stinson EB, Popp RL. A hemodynamic and Doppler echocardiographic study of ventricular function in long term cardiac allograft recipients: etiology and prognosis of restrictive/constrictive physiology. Circulation. 1989; 79:66-75.
    View PubMed
  79. Nellessen U, Masuyama T, Appleton CP, Tye T, Popp RL. Mitral prosthesis malfunction: serial Doppler echocardiographic studies of mitral prostheses before and after replacement. Circulation. 1989; 79:330-6.
    View PubMed
  80. Hatle LK, Appleton CP, Popp RL. Differentiation of constrictive pericarditis and restrictive cardiomyopathy by Doppler echocardiography. Circulation. 1989; 79:357-70.
    View PubMed
  81. Reed KL, Appleton CP, Sahn DJ, Anderson CF. Human fetal tricuspid and mitral deceleration time: changes with normal pregnancy and intrauterine growth retardation. Am J Obstetrics and Gynecology. 1989; 161:1532-5.


Appointments | Contact Us | Give to Mayo Clinic | Search

LEGAL RESTRICTIONS AND TERMS OF USE APPLICABLE TO THIS SITE

Use of this site signifies your agreement to the terms of use.
© 2013 Mayo Foundation for Medical Education and Research. All rights reserved.