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Publications - Paul D . Brown, M.D.

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  1. Macdonald OK, Kruse JJ, Miller JM, Garces YI, Brown PD, Miller RC, Foote RL. Proton beam radiotherapy versus three-dimensional conformal stereotactic body radiotherapy in primary peripheral, early-stage non-small-cell lung carcinoma: a comparative dosimetric analysis. Int J Radiat Oncol Biol Phys 2009 Nov 1; 75(3):950-8.
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  2. Schomas DA, Laack NN, Brown PD. Low-grade gliomas in older patients: long-term follow-up from Mayo Clinic. Cancer 2009 Sep 1; 115(17):3969-78.
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  3. Pollock BE, Jacob JT, Brown PD, Nippoldt TB. Radiosurgery of growth hormone-producing pituitary adenomas: factors associated with biochemical remission. J Neurosurg 2009 Sep; 111(Suppl S):170-5.
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  4. Schomas DA, Laack NN, Rao RD, Meyer FB, Shaw EG, O'Neill BP, Giannini C, Brown PD. Intracranial low-grade gliomas in adults: 30-year experience with long-term follow-up at Mayo Clinic. Neuro Oncol 2009 Aug; 11(4):437-45. Epub 2008 Nov 18.
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  5. Daniels TB, Pollock BE, Miller RC, Lucchinetti CF, Leavitt JA, Brown PD. Radiation-induced optic neuritis after pituitary adenoma radiosurgery in a patient with multiple sclerosis: case report. J Neurooncol 2009 Jun; 93(2):263-7.
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  6. Daniels TB, Pollock BE, Miller RC, Lucchinetti CF, Leavitt JA, Brown PD. Radiation-induced optic neuritis after pituitary adenoma radiosurgery in a patient with multiple sclerosis: case report. J Neurooncol 2009 Jun; 93(2):263-7. Epub 2008 Dec 20.
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  7. Vogelbaum MA, Berkey B, Peereboom D, Macdonald D, Giannini C, Suh JH, Jenkins R, Herman J, Brown P, Blumenthal DT, Biggs C, Schultz C, Mehta M. Phase II trial of preirradiation and concurrent temozolomide in patients with newly diagnosed anaplastic oligodendrogliomas and mixed anaplastic oligoastrocytomas: RTOG BR0131. Neuro Oncol 2009 Apr; 11(2):167-75. Epub 2008 Sep 08.
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  8. Minehan KJ, Brown PD, Scheithauer BW, Krauss WE, Wright MP. Prognosis and treatment of spinal cord astrocytoma. Int J Radiat Oncol Biol Phys 2009 Mar 1; 73(3):727-33. Epub 2008 Aug 05.
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  9. Brown PD, Krishnan S, Sarkaria JN, Wu W, Jaeckle KA, Uhm JH, Geoffroy FJ, Arusell R, Kitange G, Jenkins RB, Kugler JW, Morton RF, Rowland KM Jr, Mischel P, Yong WH, Scheithauer BW, Schiff D, Giannini C, Buckner JC, North Central Cancer Treatment Group Phase I/II trial of erlotinib and temozolomide with radiation therapy in the treatment of newly diagnosed glioblastoma multiforme: North Central Cancer Treatment Group Study N0177. J Clin Oncol 2008 Dec 1; 26(34):5603-9. Epub 2008 Oct 27.
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  10. Shaw EG, Berkey B, Coons SW, Bullard D, Brachman D, Buckner JC, Stelzer KJ, Barger GR, Brown PD, Gilbert MR, Mehta M. Recurrence following neurosurgeon-determined gross-total resection of adult supratentorial low-grade glioma: results of a prospective clinical trial. J Neurosurg 2008 Nov; 109(5):835-41.
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  11. Locke DE, Cerhan JH, Wu W, Malec JF, Clark MM, Rummans TA, Brown PD. Cognitive rehabilitation and problem-solving to improve quality of life of patients with primary brain tumors: a pilot study. J Support Oncol 2008 Nov-Dec; 6(8):383-91.
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  12. Vogelbaum MA, Berkey B, Peereboom D, Macdonald D, Giannini C, Suh JH, Jenkins R, Herman J, Brown P, Blumenthal DT, Biggs C, Schultz C, Metha M. Phase II trial of pre-irradiation and concurrent temozolomide in patients with newly diagnosed anaplastic oligodendrogliomas and mixed anaplastic oligoastrocytomas: RTOG BR0131. Neuro Oncol 2008 Sep 8. [Epub ahead of print]
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  13. Pinn ME, Gold DG, Petersen IA, Osborn TG, Brown PD, Miller RC. Systemic lupus erythematosus, radiotherapy, and the risk of acute and chronic toxicity: the Mayo Clinic Experience. Int J Radiat Oncol Biol Phys 2008 Jun 1; 71(2):498-506. Epub 2007 Dec 31.
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  14. Pollock BE, Brown PD, Nippoldt TB, Young WF Jr. Pituitary tumor type affects the chance of biochemical remission after radiosurgery of hormone-secreting pituitary adenomas. Neurosurgery 2008 Jun; 62(6):1271-6; discussion 1276-8.
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  15. McWilliams RR, Rao RD, Buckner JC, Link MJ, Markovic S, Brown PD. Melanoma-induced brain metastases. Expert Rev Anticancer Ther 2008 May; 8(5):743-55.
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  16. Brown PD, Asher AL, Farace E. Adjuvant whole brain radiotherapy: strong emotions decide but rational studies are needed. Int J Radiat Oncol Biol Phys 2008 Apr 1; 70(5):1305-9. Epub 2008 Jan 30.
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  17. Pollock BE, Cochran J, Natt N, Brown PD, Erickson D, Link MJ, Garces YI, Foote RL, Stafford SL, Schomberg PJ. Gamma knife radiosurgery for patients with nonfunctioning pituitary adenomas: results from a 15-year experience. Int J Radiat Oncol Biol Phys 2008 Apr 1; 70(5):1325-9. Epub 2007 Oct 29.
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  18. Brown PD, Decker PA, Rummans TA, Clark MM, Frost MH, Ballman KV, Arusell RM, Buckner JC. A prospective study of quality of life in adults with newly diagnosed high-grade gliomas: comparison of patient and caregiver ratings of quality of life. Am J Clin Oncol 2008 Apr; 31(2):163-8.
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  19. Gold DG, Miller RC, Pinn ME, Osborn TG, Petersen IA, Brown PD. Chronic toxicity risk after radiotherapy for patients with systemic sclerosis (systemic scleroderma) or systemic lupus erythematosus: association with connective tissue disorder severity. Radiother Oncol 2008 Apr; 87(1):127-31. Epub 2007 Dec 26.
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  20. Shintani SA, Foote RL, Lowe VJ, Brown PD, Garces YI, Kasperbauer JL. Utility of PET/CT imaging performed early after surgical resection in the adjuvant treatment planning for head and neck cancer. Int J Radiat Oncol Biol Phys 2008 Feb 1; 70(2):322-9. Epub 2007 Sep 24.
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  21. Brown PD, Brown CA, Pollock BE, Gorman DA, Foote RL. Stereotactic radiosurgery for patients with "radioresistant" brain metastases. Neurosurgery 2008 Feb; 62 Suppl 2:790-801.
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  22. Locke DE, Decker PA, Sloan JA, Brown PD, Malec JF, Clark MM, Rummans TA, Ballman KV, Schaefer PL, Buckner JC. Validation of single-item linear analog scale assessment of quality of life in neuro-oncology patients. J Pain Symptom Manage 2007 Dec; 34(6):628-38. Epub 2007 Aug 20.
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  23. Olivier KR, Schild SE, Morris CG, Brown PD, Markovic SN. A higher radiotherapy dose is associated with more durable palliation and longer survival in patients with metastatic melanoma. Cancer 2007 Oct 15; 110(8):1791-5.
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  24. Buckner JC, Brown PD, O'Neill BP, Meyer FB, Wetmore CJ, Uhm JH. Central nervous system tumors. Mayo Clin Proc 2007 Oct; 82(10):1271-86.
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  25. Johnson ME, Piderman KM, Sloan JA, Huschka M, Atherton PJ, Hanson JM, Brown PD, Rummans TA, Clark MM, Frost MH. Measuring spiritual quality of life in patients with cancer. J Support Oncol 2007 Oct; 5(9):437-42.
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  26. Schiff D, Brown PD, Giannini C. Outcome in adult low-grade glioma: the impact of prognostic factors and treatment. Neurology 2007 Sep 25; 69(13):1366-73.
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  27. Lapid MI, Rummans TA, Brown PD, Frost MH, Johnson ME, Huschka MM, Sloan JA, Richardson JW, Hanson JM, Clark MM. Improving the quality of life of geriatric cancer patients with a structured multidisciplinary intervention: a randomized controlled trial. Palliat Support Care 2007 Jun; 5(2):107-14.
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  28. Pollock BE, Jacob JT, Brown PD, Nippoldt TB. Radiosurgery of growth hormone-producing pituitary adenomas: factors associated with biochemical remission. J Neurosurg 2007 May; 106(5):833-8.
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  29. Rao RD, Brown PD, Buckner JC. Innovation in the management of brain metastases. Oncology (Williston Park) 2007 Apr; 21(4):473-81; discussion 482, 484, 489.
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  30. Rao RD, Brown PD, Buckner JC. Innovation in the management of brain metastases. Oncology (Williston Park) 2007 Apr; 21(4):473-81; discussion 482, 484, 489.
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  31. Leenstra JL, Rodriguez FJ, Frechette CM, Giannini C, Stafford SL, Pollock BE, Schild SE, Scheithauer BW, Jenkins RB, Buckner JC, Brown PD. Central neurocytoma: management recommendations based on a 35-year experience. Int J Radiat Oncol Biol Phys 2007 Mar 15; 67(4):1145-54 Epub 2007 Jun 30.
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  32. Foote RL, Brown PD, Garces YI, Okuno SH, Miller RC, Strome SE. Informed consent in advanced laryngeal cancer. Head Neck 2007 Mar; 29(3):230-5.
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  33. Hussain A, Brown PD, Stafford SL, Pollock BE. Stereotactic radiosurgery for brainstem metastases: Survival, tumor control, and patient outcomes. Int J Radiat Oncol Biol Phys 2007 Feb 1; 67(2):521-4 Epub 2006-11-09.
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  34. Ballman KV, Buckner JC, Brown PD, Giannini C, Flynn PJ, LaPlant BR, Jaeckle KA. The relationship between six-month progression-free survival and 12-month overall survival end points for phase II trials in patients with glioblastoma multiforme. Neuro-oncol 2007 Jan; 9(1):29-38.
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  35. Miller JJ, Frost MH, Rummans TA, Huschka M, Atherton P, Brown P, Gamble G, Richardson J, Hanson J, Sloan JA, Clark MM. Role of a medical social worker in improving quality of life for patients with advanced cancer with a structured multidisciplinary intervention. J Psychosoc Oncol 2007; 25(4):105-19.
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  36. Brown PD, Jensen AW, Felten SJ, Ballman KV, Schaefer PL, Jaeckle KA, Cerhan JH, Buckner JC. Detrimental effects of tumor progression on cognitive function of patients with high-grade glioma. J Clin Oncol 2006 Dec 1; 24(34):5427-33.
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  37. Miller RC, Lachance DH, Lucchinetti CF, Keegan BM, Gavrilova RH, Brown PD, Weinshenker BG, Rodriguez M. Multiple sclerosis, brain radiotherapy, and risk of neurotoxicity: the Mayo Clinic experience. Int J Radiat Oncol Biol Phys 2006 Nov 15; 66(4):1178-86. Epub 2006 Sep 11.
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  38. Jenkins RB, Blair H, Ballman KV, Giannini C, Arusell RM, Law M, Flynn H, Passe S, Felten S, Brown PD, Shaw EG, Buckner JC. A t(1;19)(q10;p10) mediates the combined deletions of 1p and 19q and predicts a better prognosis of patients with oligodendroglioma. Cancer Res 2006 Oct 15; 66(20):9852-61.
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  39. Laack NN, Ballman KV, Brown PB, O'Neill BP, North Central Cancer Treatment Group. Whole-brain radiotherapy and high-dose methylprednisolone for elderly patients with primary central nervous system lymphoma: Results of North Central Cancer Treatment Group (NCCTG) 96-73-51. Int J Radiat Oncol Biol Phys 2006 Aug 1; 65(5):1429-39.
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  40. Foote RL, Foote RT, Brown PD, Garces YI, Okuno SH, Strome SE. Organ preservation for advanced laryngeal carcinoma. Head Neck 2006 Aug; 28(8):689-96.
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  41. Krych AJ, Foote RL, Brown PD, Garces YI, Link MJ. Long-term results of irradiation for paraganglioma. Int J Radiat Oncol Biol Phys 2006 Jul 15; 65(4):1063-6. Epub 2006 May 06.
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  42. Krishnan S, Brown PD, Ballman KV, Fiveash JB, Uhm JH, Giannini C, Jaeckle KA, Geoffroy FJ, Nabors LB, Buckner JC, North Central Cancer Treatment Group. Phase I trial of erlotinib with radiation therapy in patients with glioblastoma multiforme: results of North Central Cancer Treatment Group protocol N0177. Int J Radiat Oncol Biol Phys 2006 Jul 15; 65(4):1192-9. Epub 2006 Apr 19.
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  43. Krishnan S, Brown PD, Ballman KV, Fiveash J, Uhm JH, Giannini C, Jaeckle KA, Geoffroy FJ, Nabors LB, Buckner JC. Phase I trial of erlotinib with radiation therapy in patients with glioblastoma multiforme: Results of north central cancer treatment group protocol N0177. Int J Radiat Oncol Biol Phys 2006 Jul 15; 65(4):1192-9.
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  44. Clark MM, Rummans TA, Sloan JA, Jensen A, Atherton PJ, Frost MH, Richardson JW, Bostwick JM, Johnson ME, Hanson JM, Brown PD. Quality of life of caregivers of patients with advanced-stage cancer. Am J Hosp Palliat Care 2006 Jun-Jul; 23(3):185-91.
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  45. Sarkaria JN, Carlson BL, Schroeder MA, Grogan P, Brown PD, Giannini C, Ballman KV, Kitange GJ, Guha A, Pandita A, James CD. Use of an orthotopic xenograft model for assessing the effect of epidermal growth factor receptor amplification on glioblastoma radiation response. Clin Cancer Res 2006 Apr 1; 12(7 Part 1):2264-71.
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  46. Meyers CA, Brown PD. Role and relevance of neurocognitive assessment in clinical trials of patients with CNS tumors. J Clin Oncol 2006 Mar 10; 24(8):1305-9.
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  47. Khuntia D, Brown P, Li J, Mehta MP. Whole-brain radiotherapy in the management of brain metastasis. J Clin Oncol 2006 Mar 10; 24(8):1295-304.
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  48. Brown PD, Ballman KV, Rummans TA, Maurer MJ, Sloan JA, Boeve BF, Gupta L, Tang-Wai DF, Arusell RM, Clark MM, Buckner JC. Prospective study of quality of life in adults with newly diagnosed high-grade gliomas. J Neurooncol 2006 Feb; 76(3):283-91.
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  49. Brown P, Clark MM, Atherton P, Huschka M, Sloan JA, Gamble G, Girardi J, Frost MH, Piderman K, Rummans TA. Will improvement in quality of life (QOL) impact fatigue in patients receiving radiation therapy for advanced cancer? Am J Clin Oncol 2006 Feb; 29(1):52-8.
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  50. Brown PD. Low-grade gliomas: the debate continues. Curr Oncol Rep 2006 Jan; 8(1):71-7.
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  51. Brown PD, Foote RL, McLaughlin MP, Halyard MY, Ballman KV, Collie AC, Miller RC, Flemming KD, Hallett JW. A historical prospective cohort study of carotid artery stenosis after radiotherapy for head and neck malignancies. Int J Radiat Oncol Biol Phys 2005 Dec 1; 63(5):1361-7.
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  52. Laack NN, Brown PD, Ivnik RJ, Furth AF, Ballman KV, Hammack JE, Arusell RM, Shaw EG, Buckner JC. Cognitive function after radiotherapy for supratentorial low-grade glioma: A North Central Cancer Treatment Group prospective study. International Journal of Radiation Oncology, Biology, Physics 2005 Nov 15; 63(4):1175-83.
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  53. McWilliams RR, Rao RD, Brown PD, Link MJ, Buckner JC. Treatment options for brain metastases from melanoma. Expert Review of Anticancer Therapy 2005 Oct; 5(5):809-20.
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  54. Brown PD, Maurer MJ, Rummans TA, Pollock BE, Ballman KV, Sloan JA, Boeve BF, Arusell RM, Clark MM, Buckner JC. A prospective study of quality of life in adults with newly diagnosed high-grade gliomas: The impact of the extent of resection on quality of life and survival. Neurosurgery 2005 Sep; 57(3):495-503.
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  55. Jensen AW, Brown PD, Pollock BE, Stafford SL, Link MJ, Garces YI, Foote RL, Gorman DA, Schomberg PJ. Gamma knife radiosurgery of radiation-induced intracranial tumors: Local control, outcomes, and complications. Int J Radiat Oncol Biol Phys 2005 May 1; 62(1):32-7.
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  56. Krishnan S, Foote RL, Brown PD, Pollock BE, Link MJ, Garces YI. Radiosurgery for cranial base chordomas and chondrosarcomas. Neurosurgery 2005 Apr; 56(4):777-83.
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  57. Foote RL, Kasperbauer JL, Okuno SH, Nichols DA, Olsen KD, Brown PD, Garces YI, Sargent DJ, Strome SE. A pilot study of high-dose intraarterial cisplatin chemotherapy with concomitant accelerated radiotherapy for patients with previously untreated T4 and selected patients with T3N0-N3M0 squamous cell carcinoma of the upper aerodigestive tract. Cancer 2005 Feb 1; 103(3):559-68.
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  58. Pollock BE, Foote RL, Link MJ, Stafford SL, Brown PD, Schomberg PJ. Repeat radiosurgery for idiopathic trigeminal neuralgia. Int J Radiat Oncol Biol Phys 2005 Jan 1; 61(1):192-5.
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  59. Olivier KR, Brown PD, Stafford SL, Ansell SM, Martenson JA Jr. Efficacy and treatment-related toxicity of radiotherapy for early-stage primary non-Hodgkin lymphoma of the parotid gland. Int J Radiat Oncol Biol Phys 2004 Dec 1; 60(5):1510-4.
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  60. Prisciandaro JI, Frechette CM, Herman MG, Brown PD, Garces YI, Foote RL. A methodology to determine margins by EPID measurements of patient setup variation and motion as applied to immobilization devices. Med Phys 2004 Nov; 31(11):2978-88.
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  61. Laack NN, Brown PD. Cognitive sequelae of brain radiation on adults. Semin Oncol 2004 Oct; 31(5):702-13.
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  62. Brown PD, Buckner JC, O'Fallon JR, Iturria NL, O'Neill BP, Brown CA, Scheithauer BW, Dinapoli RP, Arusell RM, Curran WJ, Abrams R, Shaw EG. Importance of baseline mini-mental state examination as a prognostic factor for patients with low-grade glioma. Int J Radiat Oncol Biol Phys 2004 May 1; 59(1):117-25.
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  63. Krishnan S, Brown PD, Scheithauer BW, Ebersold MJ, Hammack JE, Buckner JC. Choroid plexus papillomas: a single institutional experience. J Neurooncol 2004 May; 68(1):49-55.
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  64. Brown PD, Buckner JC, O'Fallon JR, Iturria NL, Brown CA, O'Neill BP, Scheithauer BW, Dinapoli RP, Arusell RM, Abrams RA, Curran WJ, Shaw EG. Adult patients with supratentorial pilocytic astrocytomas: A prospective multicenter clinical trial. Int J Radiat Oncol Biol Phys 2004 Mar 15; 58(4):1153-60.
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  65. Pollock BE, Gorman DA, Brown PD. Radiosurgery for arteriovenous malformations of the basal ganglia, thalamus, and brainstem. J Neurosurg 2004 Feb; 100(2):210-4.
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  66. Pollock BE, Link MJ, Foote RL, Stafford SL, Brown PD, Schomberg PJ. Radiosurgery as primary management for meningiomas extending into the internal auditory canal. Stereotactic & Functional Neurosurgery 2004; 82(2-3):98-103.
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  67. Brown PD, Kline RW, Petersen IA, Haddock MG. Irradiation of the inguinal lymph nodes in patients of differing body habitus: A comparison of techniques and resulting normal tissue complication probabilities. Med Dosim 2004; 29(3):217-22.
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  68. McWilliams RR, Brown PD, Buckner JC, Link MJ, Markovic SN. Treatment of brain metastases from melanoma. Mayo Clin Proc 2003 Dec; 78(12):1529-36.
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  69. Foote RL, Brown PD, Garces YI, McIver B, Kasperbauer JL. Is there a role for radiation therapy in the management of Hurthle cell carcinoma? Int J Radiat Oncol Biol Phys 2003 Jul 15; 56(4):1067-72.
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  70. Brown PD, Buckner JC, O'Fallon JR, Iturria NL, Brown CA, O'Neill BP, Scheithauer BW, Dinapoli RP, Arusell RM, Curran WJ, Abrams R, Shaw EG. Effects of radiotherapy on cognitive function in patients with low-grade glioma measured by the Folstein Mini-Mental State Examination. J Clin Oncol 2003 Jul 1; 21(13):2519-24.
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  71. Brown PD, Buckner JC, Uhm JH, Shaw EG. The neurocognitive effects of radiation in adult low-grade glioma patients. Neuro-oncol 2003 Jul; 5(3):161-7.
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  72. Stafford SL, Pollock BE, Leavitt JA, Foote RL, Brown PD, Link MJ, Gorman DA, Schomberg PJ. A study on the radiation tolerance of the optic nerves and chiasm after stereotactic radiosurgery. Int J Radiat Oncol Biol Phys 2003 Apr 1; 55(5):1177-81.
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  73. Bartleson JD, Krecke KN, O'Neill BP, Brown PD. Reversible, strokelike migraine attacks in patients with previous radiation therapy. Neuro-oncol 2003 Apr; 5(2):121-7.
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  74. Buckner JC, Gesme D, O'Fallon JR, Hammack JE, Stafford S, Brown PD, Hawkins R, Scheithauer BW, Erickson BJ, Levitt R, Shaw EG, Jenkins R. Phase II trial of procarbazine, lomustine, and vincristine as initial therapy for patients with low-grade oligodendroglioma or oligoastrocytoma: Efficacy and associations with chromosomal abnormalities. J Clin Oncol 2003 Jan 15; 21(2):251-5.
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  75. Pollock BE, Brown PD, Foote RL, Stafford SL, Schomberg PJ. Properly selected patients with multiple brain metastases may benefit from aggressive treatment of their intracranial disease. J Neurooncol 2003 Jan; 61(1):73-80.
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  76. Sarkar A, Pollock BE, Brown PD, Gorman DA. Evaluation of gamma knife radiosurgery in the treatment of oligodendrogliomas and mixed oligodendroastrocytomas. J Neurosurg 2002 Dec; 97(Suppl 5):653-6.
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  77. Brown PD, Brown CA, Pollock BE, Gorman DA, Foote RL. Stereotactic radiosurgery for patients with "radioresistant" brain metastases. Neurosurgery 2002 Sep; 51(3):656-65.
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  78. Brown PD, Bonner JA, Foote RL, Frytak S, Marks RS, Richardson RL, Creagan ET. Long-term results of a phase I/II study of high-dose thoracic radiotherapy with concomitant cisplatin and etoposide in limited stage small-cell lung cancer. Am J Clin Oncol 2001 Dec; 24(6):556-61.
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  79. Brown PD, Eshleman JS, Foote RL, Strome SE. An analysis of facial nerve function in irradiated and unirradiated facial nerve grafts. Int J Radiat Oncol Biol Phys 2000 Oct 1; 48(3):737-43.
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  80. Brown PD, Stafford SL, Schild SE, Martenson JA, Schiff D. Metastatic spinal cord compression in patients with colorectal cancer. J Neurooncol 1999 Sep; 44(2):175-80.
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  81. Schild SE, Stafford SL, Brown PD, Wood CP, Scheithauer BW, Schomberg PJ, Wong WW, Lyons MK, Shaw EG. The results of radiotherapy for brainstem tumors. J Neurooncol 1998 Nov; 40(2):171-7.
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