Publications - Thomas G. Brott, M.D.

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  1. Barrett KM, Ossi RG, Brott TG, Meschia JF. Clinical, anatomic, and procedural durability of carotid revascularization. J Stroke Cerebrovasc Dis. 2013 Apr; 22(3):218-26. Epub 2011 Sep 13.
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  2. Blackshear JL, Brott TG. Ascertainment of any and all neurologic and myocardial damage in carotid revascularization: the key to optimization? Expert Rev Cardiovasc Ther. 2013 Apr; 11(4):469-84.
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  3. Anderson CD, Biffi A, Nalls MA, Devan WJ, Schwab K, Ayres AM, Valant V, Ross OA, Rost NS, Saxena R, Viswanathan A, Worrall BB, Brott TG, Goldstein JN, Brown D, Broderick JP, Norrving B, Greenberg SM, Silliman SL, Hansen BM, Tirschwell DL, Lindgren A, Common variants within oxidative phosphorylation genes influence risk of ischemic stroke and intracerebral hemorrhage. Stroke. 2013 Mar; 44(3):612-9.
  4. Timaran CH, Mantese VA, Malas M, Brown OW, Lal BK, Moore WS, Voeks JH, Brott TG, CREST Investigators. Differential outcomes of carotid stenting and endarterectomy performed exclusively by vascular surgeons in the Carotid Revascularization Endarterectomy versus Stenting Trial (CREST). J Vasc Surg. 2013 Feb; 57(2):303-8. Epub 2012 Dec 20.
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  5. Heckman MG, Soto-Ortolaza AI, Diehl NN, Rayaprolu S, Brott TG, Wszolek ZK, Meschia JF, Ross OA. Genetic variants associated with myocardial infarction in the PSMA6 gene and Chr9p21 are also associated with ischaemic stroke. Eur J Neurol. 2013 Feb; 20(2):300-8. Epub 2012 Aug 06.
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  6. Hill MD, Brooks W, Mackey A, Clark WM, Meschia JF, Morrish WF, Mohr JP, Rhodes JD, Popma JJ, Lal BK, Longbottom ME, Voeks JH, Howard G, Brott TG, for the CREST Investigators. Stroke After Carotid Stenting and Endarterectomy in the Carotid Revascularization Endarterectomy Versus Stenting Trial (CREST). Circulation. 2012 Dec 18; 126(25):3054-61. Epub 2012 Nov 16.
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  7. Habersberger J, Brott TG, Roubin GS. Carotid artery stenting: a clinical update. Curr Opin Cardiol. 2012 Nov; 27(6):565-71.
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  8. Holliday EG, Maguire JM, Evans TJ, Koblar SA, Jannes J, Sturm JW, Hankey GJ, Baker R, Golledge J, Parsons MW, Malik R, McEvoy M, Biros E, Lewis MD, Lincz LF, Peel R, Oldmeadow C, Smith W, Moscato P, Barlera S, Bevan S, Bis JC, Boerwinkle E, Boncoraglio Common variants at 6p21.1 are associated with large artery atherosclerotic stroke. Nat Genet. 2012 Oct; 44(10):1147-51. Epub 2012 Sep 02.
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  9. Lal BK, Beach KW, Roubin GS, Lutsep HL, Moore WS, Malas MB, Chiu D, Gonzales NR, Burke JL, Rinaldi M, Elmore JR, Weaver FA, Narins CR, Foster M, Hodgson KJ, Shepard AD, Meschia JF, Bergelin RO, Voeks JH, Howard G, Brott TG, for the CREST Investigators. Restenosis after carotid artery stenting and endarterectomy: a secondary analysis of CREST, a randomised controlled trial. Lancet Neurol. 2012 Sep; 11(9):755-63. Epub 2012 Aug 2.
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  10. Vilain KR, Magnuson EA, Li H, Clark WM, Begg RJ, Sam AD 2nd, Sternbergh WC 3rd, Weaver FA, Gray WA, Voeks JH, Brott TG, Cohen DJ, CREST Investigators. Costs and cost-effectiveness of carotid stenting versus endarterectomy for patients at standard surgical risk: results from the Carotid Revascularization Endarterectomy Versus Stenting Trial (CREST). Stroke. 2012 Sep; 43(9):2408-16. Epub 2012 Jul 19.
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  11. Longbottom ME, Roberts JN, Tom M, Hughes SE, Howard VJ, Sheffet AJ, Meschia JF, Brott TG, CREST Investigators. Interventions to increase enrollment in a large multicenter phase 3 trial of carotid stenting vs. endarterectomy. Int J Stroke. 2012 Aug; 7(6):447-53. Epub 2012 May 28.
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  12. Cheng YC, Anderson CD, Bione S, Keene K, Maguire JM, Nalls M, Rasheed A, Zeginigg M, Attia J, Baker R, Barlera S, Biffi A, Bookman E, Brott TG, Brown RD Jr, Chen F, Chen WM, Ciusani E, Cole JW, Cortellini L, Danesh J, Doheny K, Ferrucci L, Grazia Franzosi Are myocardial infarction--associated single-nucleotide polymorphisms associated with ischemic stroke? Stroke. 2012 Apr; 43(4):980-6. Epub 2012 Feb 23.
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  13. Voeks JH, Howard G, Roubin GS, Malas MB, Cohen DJ, Sternbergh WC 3rd, Aronow HD, Eskandari MK, Sheffet AJ, Lal BK, Meschia JF, Brott TG, CREST Investigators. Age and outcomes after carotid stenting and endarterectomy: the carotid revascularization endarterectomy versus stenting trial. Stroke. 2011 Dec; 42(12):3484-90. Epub 2011 Oct 06.
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  14. Cohen DJ, Stolker JM, Wang K, Magnuson EA, Clark WM, Demaerschalk BM, Sam AD Jr, Elmore JR, Weaver FA, Aronow HD, Goldstein LB, Roubin GS, Howard G, Brott TG, CREST Investigators. Health-related quality of life after carotid stenting versus carotid endarterectomy: results from CREST (Carotid Revascularization Endarterectomy Versus Stenting Trial). J Am Coll Cardiol. 2011 Oct 4; 58(15):1557-65.
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  15. Meschia JF, Nalls M, Matarin M, Brott TG, Brown RD Jr, Hardy J, Kissela B, Rich SS, Singleton A, Hernandez D, Ferrucci L, Pearce K, Keller M, Worrall BB, Siblings With Ischemic Stroke Study Investigators. Siblings with ischemic stroke study: results of a genome-wide scan for stroke loci. Stroke. 2011 Oct; 42(10):2726-32. Epub 2011 Sep 22.
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  16. Blackshear JL, Cutlip DE, Roubin GS, Hill MD, Leimgruber PP, Begg RJ, Cohen DJ, Eidt JF, Narins CR, Prineas RJ, Glasser SP, Voeks JH, Brott TG, CREST Investigators. Myocardial infarction after carotid stenting and endarterectomy: results from the carotid revascularization endarterectomy versus stenting trial. Circulation. 2011 Jun 7; 123(22):2571-8. Epub 2011 May 23.
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  17. Howard VJ, Lutsep HL, Mackey A, Demaerschalk BM, Sam AD 2nd, Gonzales NR, Sheffet AJ, Voeks JH, Meschia JF, Brott TG, CREST investigators. Influence of sex on outcomes of stenting versus endarterectomy: a subgroup analysis of the Carotid Revascularization Endarterectomy versus Stenting Trial (CREST). Lancet Neurol. 2011 Jun; 10(6):530-7. Epub 2011 May 5.
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  18. Barrett KM, Brott TG, Brown RD Jr, Carter RE, Geske JR, Graff-Radford NR, McNeil RB, Meschia JF, Mayo Acute Stroke Trial for Enhancing Recovery (MASTER) Study Group. Enhancing recovery after acute ischemic stroke with donepezil as an adjuvant therapy to standard medical care: results of a phase IIA clinical trial. J Stroke Cerebrovasc Dis. 2011 May-Jun; 20(3):177-82. Epub 2011 Feb 03.
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  19. Silver FL, Mackey A, Clark WM, Brooks W, Timaran CH, Chiu D, Goldstein LB, Meschia JF, Ferguson RD, Moore WS, Howard G, Brott TG, CREST Investigators. Safety of stenting and endarterectomy by symptomatic status in the Carotid Revascularization Endarterectomy Versus Stenting Trial (CREST). Stroke. 2011 Mar; 42(3):675-80. Epub 2011 Feb 09.
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  20. Anderson CD, Biffi A, Rahman R, Ross OA, Jagiella JM, Kissela B, Cole JW, Cortellini L, Rost NS, Cheng YC, Greenberg SM, de Bakker PI, Brown RD Jr, Brott TG, Mitchell BD, Broderick JP, Worrall BB, Furie KL, Kittner SJ, Woo D, Slowik A, Meschia JF, Saxena Common mitochondrial sequence variants in ischemic stroke. Ann Neurol. 2011 Mar; 69(3):471-80. Epub 2010 Sep 13.
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  21. Brott T, Halperin J, Abbara S, Bacharach JM, Barr J, Bush R, Cates C, Creager M, Fowler S, Friday G, Hertzberg V, McIff B, Moore W, Panago P, Riles T, Rosenwasser R, Taylor A. ASA/ACCF/AHA/AANN/AANS/ACR/ASNR/CNS/SAIP/SCAI/SIR/SNIS/SVM/SVS Guideline on the Management of Patients With Extracranial Carotid and Vertebral Artery Disease Stroke. 2011 Jan 31. [Epub ahead of print]
  22. Brott T, Halperin J, Abbara S, Bacharach JM, Barr J, Bush R, Cates C, Creager M, Fowler S, Friday G, Hertzberg V, McIff B, Moore W, Panago P, Riles T, Rosenwasser R, Taylor A. ASA/ACCF/AHA/AANN/AANS/ACR/ASNR/CNS/SAIP/SCAI/SIR/SNIS/SVM/SVS Guideline on the Management of Patients With Extracranial Carotid and Vertebral Artery Disease. Circulation. 2011 Jan 31. [Epub ahead of print]
  23. Meschia JF, Nalls M, Matarin M, Brott TG, Brown RD, Hardy J, Kissela B, Rich S, Singleton A, Hernandez D, Ferrucci L, Pearce K, Keller M, Worrall B, . Revised: Siblings with Ischemic Stroke Study (SWISS): Results of a Genome-wide Scan for Stroke Loci Stroke. 2011.
  24. Meschia JF, Singleton A, Nalls MA, Rich SS, Sharma P, Ferrucci L, Matarin M, Hernandez DG, Pearce K, Brott TG, Brown RD Jr, Hardy J, Worrall BB. Genomic risk profiling of ischemic stroke: results of an international genome-wide association meta-analysis. PLoS One. 2011; 6(9):e23161. Epub 2011 Sep 21.
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  25. Perkins WJ, Lanzino G, Brott TG. Carotid stenting vs endarterectomy: new results in perspective. Mayo Clin Proc. 2010 Dec; 85(12):1101-8.
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  26. Rost NS, Rahman RM, Biffi A, Smith EE, Kanakis A, Fitzpatrick K, Lima F, Worrall BB, Meschia JF, Brown RD Jr, Brott TG, Sorensen AG, Greenberg SM, Furie KL, Rosand J. White matter hyperintensity volume is increased in small vessel stroke subtypes. Neurology. 2010 Nov 9; 75(19):1670-7.
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  27. Barrett KM, Brott TG. Management of stenosis of the extracranial internal carotid artery: endarterectomy versus angioplasty and stenting. Curr Treat Options Neurol. 2010 Nov; 12(6):475-82.
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  28. Mantese VA, Timaran CH, Chiu D, Begg RJ, Brott TG, CREST Investigators. The Carotid Revascularization Endarterectomy versus Stenting Trial (CREST): stenting versus carotid endarterectomy for carotid disease. Stroke. 2010 Oct; 41(10 Suppl):S31-4.
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  29. Brott TG, Hobson RW 2nd, Howard G, Roubin GS, Clark WM, Brooks W, Mackey A, Hill MD, Leimgruber PP, Sheffet AJ, Howard VJ, Moore WS, Voeks JH, Hopkins LN, Cutlip DE, Cohen DJ, Popma JJ, Ferguson RD, Cohen SN, Blackshear JL, Silver FL, Mohr JP, Lal BK, Stenting versus endarterectomy for treatment of carotid-artery stenosis. N Engl J Med. 2010 Jul 1; 363(1):11-23. Epub 2010 May 26.
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  30. Rush BK, McNeil RB, Gamble DM, Luke SH, Richie AN, Albers CS, Brown RD, Brott TG, Meschia JF. Behavioral symptoms in long-term survivors of ischemic stroke. J Stroke Cerebrovasc Dis. 2010 Jul-Aug; 19(4):326-32.
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  31. Meschia JF, McNeil RB, Barrett KM, Brott TG, Graff-Radford NR, Brown RD Jr. Mayo Acute Stroke Trial for Enhancing Recovery (MASTER) protocol. J Stroke Cerebrovasc Dis. 2010 Jul-Aug; 19(4):299-310.
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  32. Lees KR, Bluhmki E, von Kummer R, Brott TG, Toni D, Grotta JC, Albers GW, Kaste M, Marler JR, Hamilton SA, Tilley BC, Davis SM, Donnan GA, Hacke W, ECASS, ATLANTIS, NINDS and EPITHET rt-PA Study Group, Allen K, Mau J, Meier D, del Zoppo G, De Silva DA, Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials. Lancet. 2010 May 15; 375(9727):1695-703.
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  33. Hopkins LN, Roubin GS, Chakhtoura EY, Gray WA, Ferguson RD, Katzen BT, Rosenfield K, Goldstein J, Cutlip DE, Morrish W, Lal BK, Sheffet AJ, Tom M, Hughes S, Voeks J, Kathir K, Meschia JF, Hobson RW 2nd, Brott TG. The Carotid Revascularization Endarterectomy versus Stenting Trial: credentialing of interventionalists and final results of lead-in phase. J Stroke Cerebrovasc Dis. 2010 Mar; 19(2):153-62.
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  34. Sheffet AJ, Roubin G, Howard G, Howard V, Moore W, Meschia JF, Hobson RW 2nd, Brott TG. Design of the Carotid Revascularization Endarterectomy vs. Stenting Trial (CREST). Int J Stroke. 2010 Feb; 5(1):40-6.
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  35. Lal BK, Brott TG. The Carotid Revascularization Endarterectomy vs. Stenting Trial completes randomization: lessons learned and anticipated results. J Vasc Surg. 2009 Nov; 50(5):1224-31.
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  36. Matarin M, Brown WM, Dena H, Britton A, De Vrieze FW, Brott TG, Brown RD Jr, Worrall BB, Case LD, Chanock SJ, Metter EJ, Ferruci L, Gamble D, Hardy JA, Rich SS, Singleton A, Meschia JF. Candidate gene polymorphisms for ischemic stroke. Stroke. 2009 Nov; 40(11):3436-42. Epub 2009 Sep 03.
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  37. Richie AN, Trejo J, Bowers CG, McNeil RB, Gamble DM, Luke SH, Brown RD Jr, Brott TG, Kissela BM, Worrall BB, Meschia JF, SWISS Group. Joint Commission primary stroke center certification does not affect proband enrollment: the siblings with ischemic stroke study. J Stroke Cerebrovasc Dis. 2009 Sep-Oct; 18(5):363-6.
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  38. Stroud N, Mazwi TM, Case LD, Brown RD Jr, Brott TG, Worrall BB, Meschia JF, Ischemic Stroke Genetics Study Investigators. Prestroke physical activity and early functional status after stroke. J Neurol Neurosurg Psychiatry. 2009 Sep; 80(9):1019-22. Epub 2009 Jul 14.
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  39. Howard VJ, Voeks JH, Lutsep HL, Mackey A, Milot G, Sam AD 2nd, Tom M, Hughes SE, Sheffet AJ, Longbottom M, Avery JB, Hobson RW 2nd, Brott TG. Does sex matter? Thirty-day stroke and death rates after carotid artery stenting in women versus men: results from the Carotid Revascularization Endarterectomy versus Stenting Trial (CREST) lead-in phase. Stroke. 2009 Apr; 40(4):1140-7. Epub 2009 Feb 10.
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  40. Pancioli AM, Broderick J, Brott T, Tomsick T, Khoury J, Bean J, del Zoppo G, Kleindorfer D, Woo D, Khatri P, Castaldo J, Frey J, Gebel J Jr, Kasner S, Kidwell C, Kwiatkowski T, Libman R, Mackenzie R, Scott P, Starkman S, Thurman RJ, CLEAR Trial The combined approach to lysis utilizing eptifibatide and rt-PA in acute ischemic stroke: the CLEAR stroke trial. Stroke. 2008 Dec; 39(12):3268-76. Epub 2008 Sep 04.
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  41. Chen DT, Meschia JF, Brott TG, Brown RD, Worrall BB, Siblings with Ischemic Stroke Study Investigators. Stroke genetic research and adults with impaired decision-making capacity: a survey of IRB and investigator practices. Stroke. 2008 Oct; 39(10):2732-5. Epub 2008 Jul 24.
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  42. Kissela BM, Brott TG, Brown RD Jr, Silliman SL, Brown WM, Rich SS, Meschia JF. Proband race/ethnicity affects pedigree completion rate in a genetic study of ischemic stroke. J Stroke Cerebrovasc Dis. 2008 Sep; 17(5):299-302.
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  43. Barrett KM, Brott TG. Carotid artery stenting versus carotid endarterectomy: current status. Neurosurg Clin N Am. 2008 Jul; 19(3):447-58, vi.
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  44. Falkensammer J, Oldenburg WA, Hendrzak AJ, Neuhauser B, Pedraza O, Ferman T, Klocker J, Biebl M, Hugl B, Meschia JF, Hakaim AG, Brott TG. Evaluation of subclinical cerebral injury and neuropsychologic function in patients undergoing carotid endarterectomy. Ann Vasc Surg. 2008 Jul-Aug; 22(4):497-504. Epub 2008 May 27.
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  45. Matarin M, Simon-Sanchez J, Fung HC, Scholz S, Gibbs JR, Hernandez DG, Crews C, Britton A, De Vrieze FW, Brott TG, Brown RD Jr, Worrall BB, Silliman S, Case LD, Hardy JA, Rich SS, Meschia JF, Singleton AB. Structural genomic variation in ischemic stroke. Neurogenetics. 2008 May; 9(2):101-8. Epub 2008 Feb 21.
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  46. Nichols C, Khoury J, Brott T, Broderick J. Intravenous recombinant tissue plasminogen activator improves arterial recanalization rates and reduces infarct volumes in patients with hyperdense artery sign on baseline computed tomography. J Stroke Cerebrovasc Dis. 2008 Mar-Apr; 17(2):64-8.
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  47. Chen DT, Case LD, Brott TG, Brown RD Jr, Silliman SL, Meschia JF, Worrall BB, ISGS Investigators. Impact of restricting enrollment in stroke genetics research to adults able to provide informed consent. Stroke. 2008 Mar; 39(3):831-7. Epub 2008 Feb 07.
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  48. Matarin M, Brown WM, Hardy JA, Rich SS, Singleton AB, Brown RD Jr, Brott TG, Worrall BB, Meschia JF, SWISS Study Group, ISGS Study Group, MSGD Study Group. Association of integrin alpha2 gene variants with ischemic stroke. J Cereb Blood Flow Metab. 2008 Jan; 28(1):81-9. Epub 2007 May 30.
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  49. Freeman WD, Barrett KM, Bestic JM, Meschia JF, Broderick DF, Brott TG. Computer-assisted volumetric analysis compared with ABC/2 method for assessing warfarin-related intracranial hemorrhage volumes. Neurocrit Care. 2008; 9(3):307-12.
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  50. Barrett KM, Brott TG. Carotid endarterectomy versus angioplasty/stenting for carotid stenosis. Curr Atheroscler Rep. 2007 Oct; 9(4):333-40.
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  51. Leslie-Mazwi TM, Brott TG, Brown RD Jr, Worrall BB, Silliman SL, Case LD, Frankel MR, Rich SS, Meschia JF. Sex differences in stroke evaluations in the Ischemic Stroke Genetics Study. J Stroke Cerebrovasc Dis. 2007 Sep-Oct; 16(5):187-93.
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  52. Thompson KM, Gerlach SY, Jorn HK, Larson JM, Brott TG, Files JA. Advances in the care of patients with intracerebral hemorrhage. Mayo Clin Proc. 2007 Aug; 82(8):987-90.
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  53. Meschia JF, Brott TG, Hobson RW 2nd. Diagnosis and invasive management of carotid atherosclerotic stenosis. Mayo Clin Proc. 2007 Jul; 82(7):851-8.
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  54. Barrett KM, Freeman WD, Weindling SM, Brott TG, Broderick DF, Heckman MG, Crook JE, Divertie GD, Meschia JF. Brain injury after cardiopulmonary arrest and its assessment with diffusion-weighted magnetic resonance imaging. Mayo Clin Proc. 2007 Jul; 82(7):828-35.
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  55. Matarin M, Brown WM, Scholz S, Simon-Sanchez J, Fung HC, Hernandez D, Gibbs JR, De Vrieze FW, Crews C, Britton A, Langefeld CD, Brott TG, Brown RD Jr, Worrall BB, Frankel M, Silliman S, Case LD, Singleton A, Hardy JA, Rich SS, Meschia JF. A genome-wide genotyping study in patients with ischaemic stroke: initial analysis and data release. Lancet Neurol. 2007 May; 6(5):414-20.
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  56. Worrall BB, Brott TG, Brown RD Jr, Brown WM, Rich SS, Arepalli S, Wavrant-De Vrieze F, Duckworth J, Singleton AB, Hardy J, Meschia JF, SWISS, ISGS and MSGD I. IL1RN VNTR polymorphism in ischemic stroke: analysis in 3 populations. Stroke. 2007 Apr; 38(4):1189-96.
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  57. Wiklund PG, Brown WM, Brott TG, Stegmayr B, Brown RD Jr, Nilsson-Ardnor S, Hardy JA, Kissela BM, Singleton A, Holmberg D, Rich SS, Meschia JF. Lack of aggregation of ischemic stroke subtypes within affected sibling pairs. Neurology. 2007 Feb 6; 68(6):427-31.
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  58. Brott TG. Novel approaches to stroke prevention in atrial fibrillation: introduction. Stroke. 2007 Feb; 38(2 Suppl):614.
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  59. Barrett KM, Brott TG, Brown RD Jr, Frankel MR, Worrall BB, Silliman SL, Case LD, Rich SS, Meschia JF, Ischemic Stroke Genetics Study Group. Sex differences in stroke severity, symptoms, and deficits after first-ever ischemic stroke. J Stroke Cerebrovasc Dis. 2007 Jan-Feb; 16(1):34-9.
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  60. Meschia JF, Barrett KM, Chukwudelunzu F, Brown WM, Case LD, Kissela BM, Brown RD Jr, Brott TG, Olson TS, Rich SS, Silliman S, Worrall BB, Siblings with Ischemic Stroke Study (SWISS) Investigators. Interobserver agreement in the trial of org 10172 in acute stroke treatment classification of stroke based on retrospective medical record review. J Stroke Cerebrovasc Dis. 2006 Nov-Dec; 15(6):266-72.
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  61. Barrett KM, Brott TG. Carotid artery stenting versus carotid endarterectomy: current status. Neurol Clin. 2006 Nov; 24(4):681-95.
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  62. Meschia JF, Case LD, Worrall BB, Brown RD Jr, Brott TG, Frankel M, Silliman S, Rich SS, Ischemic Stroke Genetics Study Group. Family history of stroke and severity of neurologic deficit after stroke. Neurology. 2006 Oct 24; 67(8):1396-402.
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  63. Jauch EC, Lindsell CJ, Adeoye O, Khoury J, Barsan W, Broderick J, Pancioli A, Brott T. Lack of evidence for an association between hemodynamic variables and hematoma growth in spontaneous intracerebral hemorrhage. Stroke. 2006 Aug; 37(8):2061-5. Epub 2006 Jun 22.
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  64. He Z, Meschia JF, Brott TG, Dickson DW, McKinney M. Aging is neuroprotective during global ischemia but leads to increased caspase-3 and apoptotic activity in hippocampal neurons. Curr Neurovasc Res. 2006 Aug; 3(3):181-6.
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  65. Levy JH, Fingerhut A, Brott T, Langbakke IH, Erhardtsen E, Porte RJ. Recombinant factor VIIa in patients with coagulopathy secondary to anticoagulant therapy, cirrhosis, or severe traumatic injury: review of safety profile. Transfusion. 2006 Jun; 46(6):919-33.
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  66. Dominguez R, Vila JF, Augustovski F, Irazola V, Castillo PR, Rotta Escalante R, Brott TG, Meschia JF. Spanish cross-cultural adaptation and validation of the National Institutes of Health Stroke Scale. Mayo Clin Proc. 2006 Apr; 81(4):476-80.
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  67. Freeman WD, Brott TG. Modern treatment options for intracerebral hemorrhage. Curr Treat Options Neurol. 2006 Mar; 8(2):145-57.
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  68. Meschia JF, Kissela BM, Brott TG, Brown RD Jr, Worrall BB, Beck J, Skarp AN. The Siblings With Ischemic Stroke Study (SWISS): a progress report. Clin Med Res. 2006 Mar; 4(1):12-21.
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  69. He Z, Crook JE, Meschia JF, Brott TG, Dickson DW, McKinney M. Aging blunts ischemic-preconditioning-induced neuroprotection following transient global ischemia in rats. Curr Neurovasc Res. 2005 Dec; 2(5):365-74.
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  70. He Z, Cui L, Meschia JF, Dickson DW, Brott TG, Simpkins JW, Day AL, McKinney M. Hippocampal progenitor cells express nestin following cerebral ischemia in rats. Neuroreport. 2005 Sep 28; 16(14):1541-4.
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  71. Feldmann E, Broderick JP, Kernan WN, Viscoli CM, Brass LM, Brott T, Morgenstern LB, Wilterdink JL, Horwitz RI. Major risk factors for intracerebral hemorrhage in the young are modifiable. Stroke. 2005 Sep; 36(9):1881-5.
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  72. Broderick JP, Brott T, DeGraba T, Fagan SC, Frankel MR, Grotta JC, Haley EC, Hamilton S, Kwiatkowski T, Levine SR, Lewandowski CA, Lin Y, Libman R, Lu M, Lyden P, Marler JR, Morgenstern L, Patel S, Sanders C, Tilley BC. Recombinant tissue plasminogen activator for minor strokes: The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Experience. Ann Emerg Med. 2005 Sep; 46(3):243-52.
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  73. Meschia JF, Brott TG, Brown RD Jr, Crook R, Worrall BB, Kissela B, Brown WM, Rich SS, Case LD, Evans EW, Hague S, Singleton A, Hardy J, SWISS Study Group, ISGS Study Group, MSGD Study Group. Phosphodiesterase 4D and 5-lipoxygenase activating protein in ischemic stroke. Ann Neurol. 2005 Sep; 58(3):351-61.
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  74. Hobson RW, Brott TG, Roubin GS, Silver FL, Barnett HJM. Carotid artery stenting - Meeting the recruitment challenge of a clinical trial. Stroke. 2005 Jun; 36(6):1314-5.
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  75. Lu M, Lyden PD, Brott TG, Hamilton S, Broderick JP, Grotta JC. Beyond subgroup analysis: improving the clinical interpretation of treatment effects in stroke research. J Neurosci Methods. 2005 Apr 30; 143(2):209-16.
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  76. Kwiatkowski T, Libman R, Tilley BC, Lewandowski C, Grotta JC, Lyden P, Levine SR, Brott T. The impact of imbalances in baseline stroke severity on outcome in the National Institute of Neurological Disorders and Stroke recombinant tissue plasminogen activator stroke study. Ann Emerg Med. 2005 Apr; 45(4):377-84.
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  77. Meschia JF, Brott TG, Brown RD Jr, Kissela BM, Hardy JA, Brown WM, Rich SS, Siblings With Ischemic Stroke Study Investigators. Correlation of proband and sibling stroke latency: the SWISS Study. Neurology. 2005 Mar 22; 64(6):1061-3.
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  78. Chen DT, Worrall BB, Brown RD, Brott TG, Kissela BM, Olson TS, Rich SS, Meschia JF. The impact of privacy protections on recruitment in a multicenter stroke genetics study. Neurology. 2005 Feb 22; 64(4):721-4.
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  79. Meschia JF, Brott TG, Brown RD Jr. Genetics of cerebrovascular disorders. Mayo Clin Proc. 2005 Jan; 80(1):122-32.
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  80. Worrall BB, Chen DT, Brown RD, Brott TG, Meschia JF. A survey of the SWISS researchers on the impact of sibling privacy protections on pedigree recruitment. Neuroepidemiology. 2005; 25(1):32-41.
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  81. Hobson RW, Howard VJ, Roubin GS, Brott TG, Ferguson RD, Popma JJ, Graham DL, Howard G. Carotid artery stenting is associated with increased complications in octogenarians: 30-day stroke and death rates in the CREST lead-in phase. J Vasc Surg. 2004 Dec; 40(6):1106-10.
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  82. Freeman WD, Brott TG, Barrett KM, Castillo PR, Deen HG Jr, Czervionke LF, Meschia JF. Recombinant factor VIIa for rapid reversal of warfarin anticoagulation in acute intracranial hemorrhage. Mayo Clin Proc. 2004 Dec; 79(12):1495-500.
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  83. Castillo PR, Brott TG, Alvarez S, Meschia JF. Creation of a bilingual Spanish-English version of the Questionnaire for Verifying Stroke-free Status. Neuroepidemiology. 2004 Sep-Oct; 23(5):236-9.
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  84. Brott TG, Brown RD Jr, Meyer FB, Miller DA, Cloft HJ, Sullivan TM. Carotid revascularization for prevention of stroke: carotid endarterectomy and carotid artery stenting. Mayo Clin Proc. 2004 Sep; 79(9):1197-208.
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  85. Hacke W, Donnan G, Fieschi C, Kaste M, von Kummer R, Broderick JP, Brott T, Frankel M, Grotta JC, Haley EC, Kwiatkowski T, Levine SR, Lewandowski C, Lu M, Lyden P, Marler JR, Patel S, Tilley BC, Albers G, Grotta J, Bluhmki PE, Wilhelm M, Hamilton S. Association of outcome with early stroke treatment: pooled analysis of ATLANTIS, ECASS, and NINDS rt-PA stroke trials. Lancet. 2004 Mar 6; 363(9411):768-74.
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  188. Brott T, Broderick JP. Intracerebral hemorrhage. Heart Disease & Stroke. 1993 Jan-Feb; 2(1):59-63.
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  189. McDowell FH, Brott T, Goldstein M, Grotta J, Heros R, Latchaw R, Robertson J, Sherman D, Starkman S, Toole J. The emergency treatment of stroke: the first six hours. Journal of Stroke and Cerebrovascular Diseases. 1993; 3:133-144.
  190. Broderick J, Brott T, Tomsick T, Leach A. Lobar hemorrhage in the elderly. The undiminishing importance of hypertension. Stroke. 1993; 24(1):49-51.
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  191. Adams HP, Brott T, Crowell R. Adult basic life support - Stroke. Health Care Provider's Manual for Basic Life Support and Textbook of Advanced Life Support Stroke. 1993.
  192. Brott T. Utility of the National Institutes of Health stroke scale. Cerebrovasc Dis. 1992 Jul-Aug; 2(4):241-2.
  193. Haley EC Jr, Levy DE, Brott TG, Sheppard GL, Wong MC, Kongable GL, Torner JC, Marler JR. Urgent therapy for stroke. Part II. Pilot study of tissue plasminogen activator administered 91-180 minutes from onset. Stroke. 1992 May; 23(5):641-5.
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  194. Brott TG, Haley EC Jr, Levy DE, Barsan W, Broderick J, Sheppard GL, Spilker J, Kongable GL, Massey S, Reed R. Urgent therapy for stroke. Part I. Pilot study of tissue plasminogen activator administered within 90 minutes. Stroke. 1992 May; 23(5):632-40.
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  195. Broderick JP, Brott T, Tomsick T, Huster G, Miller R. The risk of subarachnoid and intracerebral hemorrhages in blacks as compared with whites. N Engl J Med. 1992 Mar 12; 326(11):733-6.
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  196. Brott T. Thrombolytic therapy. Neurol Clin. 1992 Feb; 10(1):219-32.
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  197. Levine SR, Brott TG. Thrombolytic therapy in cerebrovascular disorders. Prog Cardiovasc Dis. 1992 Jan-Feb; 34(4):235-62.
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  198. Tomsick T, Brott T, Barsan W, Broderick J, Haley EC, Spilker J. Thrombus localization with emergency cerebral CT. AJNR Am J Neuroradiol. 1992 Jan-Feb; 13(1):257-63.
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  199. Adams HP, Brott T, Crowell R. Emergency cardiac care committee and subcommittees, American Heart Association. JAMA. 1992; 268:2242-2244.
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  200. Brott T, Stump D. Overview of hemostasis and thrombosis. Semin Neurol. 1991 Dec; 11(4):305-13.
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  201. , North American Symptomatic Carotid Endarterectomy Trial Collaborators. Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis. N Engl J Med. 1991 Aug 15; 325(7):445-53.
  202. Brott T. Prevention and management of medical complications of the hospitalized elderly stroke patient. Clin Geriatr Med. 1991 Aug; 7(3):475-82.
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  203. Brott T. Thrombolytic therapy for stroke. Cerebrovascular & Brain Metabolism Reviews. 1991 Summer; 3(2):91-113.
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  204. Brott T. Neurological complications of clotting disorders. Seminars in Neurology 11 1991.
  205. Tomsick TA, Brott TG, Chambers AA, Fox AJ, Gaskill MF, Lukin RR, Pleatman CW, Wiot JG, Bourekas E. Hyperdense middle cerebral artery sign on CT: efficacy in detecting middle cerebral artery thrombosis. AJNR Am J Neuroradiol. 1990 May; 11(3):473-7.
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  206. Olinger CP, Adams HP Jr, Brott TG, Biller J, Barsan WG, Toffol GJ, Eberle RW, Marler JR. High-dose intravenous naloxone for the treatment of acute ischemic stroke. Stroke. 1990 May; 21(5):721-5.
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  207. Broderick JP, Brott TG, Tomsick T, Barsan W, Spilker J. Ultra-early evaluation of intracerebral hemorrhage. J Neurosurg. 1990 Feb; 72(2):195-9.
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  208. Barsan W, Brott T. Treatment of acute ischemic stroke. Stroke, Clinical Updates. 1990; 1:1-4.
  209. Barsan WG, Brott TG, Olinger CP, Marler JR. Early treatment for acute ischemic stroke. Ann Intern Med. 1989 Sep 15; 111(6):449-51.
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  210. Barsan WG, Olinger CP, Adams HP Jr, Brott TG, Eberle R, Biller J, Biros M, Marler J. Use of high dose naloxone in acute stroke: possible side-effects. Crit Care Med. 1989 Aug; 17(8):762-7.
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  211. Brott T, Marler JR, Olinger CP, Adams HP Jr, Tomsick T, Barsan WG, Biller J, Eberle R, Hertzberg V, Walker M. Measurements of acute cerebral infarction: lesion size by computed tomography. Stroke. 1989 Jul; 20(7):871-5.
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  212. Brott T, Adams HP Jr, Olinger CP, Marler JR, Barsan WG, Biller J, Spilker J, Holleran R, Eberle R, Hertzberg V. Measurements of acute cerebral infarction: a clinical examination scale. Stroke. 1989 Jul; 20(7):864-70.
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  213. Brott T, Reed RL. Intensive care for acute stroke in the community hospital setting. The first 24 hours. Stroke. 1989 May; 20(5):694-7.
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  214. Bienenfeld D, Brott T. Capgras' syndrome following minor head trauma. J Clin Psychiatry. 1989 Feb; 50(2):68-9.
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  215. Timerding BL, Barsan WG, Hedges JR, Brott TG, VanLigten PF, Spilker JA, Olinger CP. Stroke patient evaluation in the emergency department before pharmacologic therapy. Am J Emerg Med. 1989 Jan; 7(1):11-5.
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  216. Tomsick TA, Brott TG, Olinger CP, Barsan W, Spilker J, Eberle R, Adams H. Hyperdense middle cerebral artery: incidence and quantitative significance. Neuroradiology. 1989; 31(4):312-5.
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