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Publications - Allan S . Jaffe, M.D.

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  1. Miller WL, Hartman KA, Burritt MF, Grill DE, Jaffe AS. Profiles of serial changes in cardiac troponin T concentrations and outcome in ambulatory patients with chronic heart failure. J Am Coll Cardiol 2009 Oct 27; 54(18):1715-21.
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  2. Kavsak PA, Wang XS, Ko DT, MacRae AR, Jaffe AS. Short- and long-term risk stratification using a next-generation, high-sensitivity research cardiac troponin i (hs-ctni) assay in an emergency department chest pain population. Clin Chem 2009 Oct; 55(10):1809-15.
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  3. Saenger AK, Dalenberg DA, Bryant SC, Grebe SK, Jaffe AS. Pediatric brain natriuretic peptide concentrations vary with age and sex and appear to be modulated by testosterone. Clin Chem 2009 Oct; 55(10):1869-75. Epub 2009 Aug 13.
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  4. Saenger AK, Lockwood C, Snozek CL, Milz TC, Karon BS, Scott MG, Jaffe AS. Catecholamine interference in enzymatic creatinine assays. Clin Chem 2009 Sep; 55(9):1732-6. Epub 2009 Jul 09.
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  5. Neizel M, Futterer S, Steen H, Giannitsis E, Reinhardt L, Lossnitzer D, Lehrke S, Jaffe AS, Katus HA. Predicting microvascular obstruction with cardiac troponin T after acute myocardial infarction: a correlative study with contrast-enhanced magnetic resonance imaging. Clin. res. cardiol. 2009 Sep; 98(9):555-62.
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  6. Bang HJ, Mazumdar M, Newman G, Bomback AS, Ballantyne CM, Jaffe AS, August PA, Kshirsagar AV. Screening for kidney disease in vascular patients: Screening for occult renal disease (SCORED) experience. Nephrol Dial Transplant 2009 Aug; 24(8):2452-7.
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  7. Miller WL, Burnett JC Jr, Hartman KA, Hodge DO, Giuliani I, Minard F, Larue C, Jaffe AS. Role for precursor Pro-B type natriuretic peptide in assessing response to therapy and prognosis in patients with decompensated heart failure treated with nesiritide. Clin Chim Acta 2009 Aug; 406(1-2):119-23. Epub 2009 Jun 11.
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  8. Berridge BR, Pettit S, Walker DB, Jaffe AS, Schultze AE, Herman E, Reagan WJ, Lipshultz SE, Apple FS, York MJ. A translational approach to detecting drug-induced cardiac injury with cardiac troponins: Consensus and recommendations from the Cardiac Troponins Biomarker Working Group of the Health and Environmental Sciences Institute. Am Heart J 2009 Jul; 158(1):21-9.
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  9. Kavsak PA, Wang XS, Henderson M, Ko DT, MacRae AR, Jaffe AS. PAPP-A as a marker of increased long-term risk in patients with chest pain. Clin Biochem 2009 Jul; 42(10-11):1012-8.
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  10. Landesberg G, Beattie WS, Mosseri M, Jaffe AS, Alpert JS. Perioperative myocardial infarction. Circulation 2009 Jun 9; 119(22):2936-44.
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  11. Landesberg G, Beattie WS, Mosseri M, Jaffe AS, Alpert JS. Perioperative myocardial infarction. Circulation 2009 Jun 9; 119(22):2936-44.
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  12. Landesberg G, Beattie WS, Mosseri M, Jaffe AS, Alpert JS. Perioperative Myocardial Infarction. Circulation 2009 June 9; 119(22):2936-2944.
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  13. Hickson LT, El-Zoghby ZM, Lorenz EC, Stegall MD, Jaffe AS, Cosio FG. Patient survival after kidney transplantation: relationship to pretransplant cardiac troponin T levels. Am J Transplant 2009 Jun; 9(6):1354-61. Epub 2009 May 13.
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  14. Hickson LTJ, El-Zoghby ZM, Lorenz EC, Stegall MD, Jaffe AS, Cosio FG. Patient survival after kidney transplantation: relationship to pretransplant cardiac troponin T levels. Am J Transplant 2009 Jun; 9(6):1354-61.
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  15. Feng DL, Syed IS, Martinez M, Oh JK, Jaffe AS, Grogan M, Edwards WD, Gertz MA, Klarich KW. Intracardiac thrombosis and anticoagulation therapy in cardiac amyloidosis. Circulation 2009 May 12; 119(18):2490-7.
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  16. Feng D, Syed IS, Martinez M, Oh JK, Jaffe AS, Grogan M, Edwards WD, Gertz MA, Klarich KW. Intracardiac thrombosis and anticoagulation therapy in cardiac amyloidosis. Circulation 2009 May 12; 119(18):2490-7. Epub 2009 May 04.
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  17. Carney RM, Freedland KE, Jaffe AS. Depression screening in patients with heart disease. JAMA 1 2009 Apr 1; 301(13):1337-1338.
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  18. Gerber Y, Dunlay SM, Jaffe AS, McConnell JP, Weston SA, Killian JM, Roger VL. Plasma lipoprotein-associated phospholipase A2 levels in heart failure: association with mortality in the community. Atherosclerosis 2009 Apr; 203(2):593-8. Epub 2008 Aug 07.
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  19. Vasile VC, Babuin L, Ting HH, Bell MR, Orme NM, Yuan BY, Perez JA, Alegria JR, Bellolio F, Haro LH, Jaffe AS. Aborted myocardial infarction: is it real in the troponin era? Am Heart J 2009 Apr; 157(4):636-41. Epub 2009 Jan 31.
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  20. Gerber Y, Dunlay SM, Jaffe AS, McConnell JP, Weston SA, Killian JM, Roger VL. Plasma lipoprotein-associated phospholipase A2 levels in heart failure: association with mortality in the community. Atherosclerosis 2009 Apr; 203(2):593-598.
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  21. Carney RM, Freedland KE, Steinmeyer B, Blumenthal JA, de Jonge P, Davidson KW, Czajkowski SM, Jaffe AS. History of depression and survival after acute myocardial infarction. Psychosom Med 2009 Apr; 71(3):253-9. Epub 2009 Feb 27.
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  22. Carney RM, Freedland KE, Steinmeyer B, Blumenthal JA, de Jonge P, Davidson KW, Czajkowski SM, Jaffe AS. History of depression and survival after acute myocardial infarction. Psychosom Med 2009 Apr; 71(3):253-9.
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  23. Bang H, Mazumdar M, Newman G, Bomback AS, Ballantyne CM, Jaffe AS, August PA, Kshirsagar AV. Screening for kidney disease in vascular patients: screening for occult renal disease (SCORED) experience. Nephrol Dial Transplant (In press) 2009 Mar 26; 26(epub).
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  24. Kavsak PA, Wang X, Henderson M, Ko DT, Macrae AR, Jaffe AS. PAPP-A as a marker of increased long-term risk in patients with chest pain. Clin Biochem (In press) 2009 Mar 25; epub).
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  25. Lett HS, Blumenthal JA, Babyak MA, Catellier DJ, Carney RM, Berkman LF, Burg MM, Mitchell P, Jaffe AS, Schneiderman N. Dimensions of social support and depression in patients at increased psychosocial risk recovering from myocardial infarction. Int J Behav Med ( (In press) 2009 Mar 14; epub).
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  26. Kavsak PA, MacRae AR, Yerna MJ, Jaffe AS. Analytic and clinical utility of a next-generation, highly sensitive cardiac troponin I assay for early detection of myocardial injury. Clin Chem 2009 Mar; 55(3):573-577.
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  27. BursiF, Barbieri A, Politi L, Di Girolamo A, Malagoli A, Grimaldi T, Rumolo A, Busani S, Girardis M, Jaffe AS, Modena MG. Perioperative red blood cell transfusion and outcome in stable patients after elective major vascular surgery. Eur J Vasc Endovasc Surg 2009 Mar; 37(3):311-318.
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  28. Kavsak PA, MacRae AR, Yerna MJ, Jaffe AS. Analytic and clinical utility of a next-generation, highly sensitive cardiac troponin I assay for early detection of myocardial injury. Clin Chem 2009 Mar; 55(3):573-7. Epub 2009 Jan 23.
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  29. Bursi F, Barbieri A, Politi L, Di Girolamo A, Malagoli A, Grimaldi T, Rumolo A, Busani S, Girardis M, Jaffe AS, Modena MG. Perioperative red blood cell transfusion and outcome in stable patients after elective major vascular surgery. Eur J Vasc Endovasc Surg 2009 Mar; 37(3):311-8. Epub 2008 Dec 25.
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  30. Jaffe AS, Apple FS. Refining our criteria: a critcal challenge. Am J Clin Pathol 2009 Jan; 131(1):11-13.
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  31. McConnell JP, Jaffe AS. The spin stops here: inhibition of lipoprotein-associated phospholipase A2-- a promising target but a negative initial trial? Clin Chem 2009 Jan; 55(1):21-3. Epub 2008 Dec 01.
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  32. Miller WL, Hartman KA, Grill DE, Burnett JC Jr, Jaffe AS. Only large reductions in concentrations of natriuretic peptides (BNP and NT-proBNP) are associated with improved outcome in ambulatory patients with chronic heart failure. Clin Chem 2009 Jan; 55(1):78-84. Epub 2008 Nov 21.
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  33. Eggers KM, Jaffe AS, Lind L, Venge P, Lindahl B. Value of cardiac troponin I cutoff concentrations below the 99th percentile for clinical decision-making. Clin Chem 2009 Jan; 55(1):85-92. Epub 2008 Nov 06.
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  34. Vasile VC, Babuin L, Rio Perez JA, Alegria JR, Song LM, Chai HS, Afessa B, Jaffe AS. Long-term prognostic significance of elevated cardiac troponin levels in critically ill patients with acute gastrointestinal bleeding. Crit Care Med 2009 Jan; 37(1):140-7.
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  35. Wu AHB, Agee SJ, Lu AQ, Todd J, Jaffe AS. Specificity of a high sensitivity cardiac troponin-I assay utilizing single molecule counting technology. Clin Chem 2009; 55(1):196-198.
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  36. Miller WL, Hartman KA, Grill DE, Burnett JC Jr, Jaffe AS. Only large reductions in concentrations of natriuretic peptides (BNP and NT-proBNP) are associated with improved outcome in ambulatory patients with chronic heart failure. Clin Chem 2009; 55(1):78-84.
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  37. Eggers KM, Jaffe AS, Lind L, Venge P, Lindahl B. Value of cardiac troponin I cutoff concentrations below the 99th percentile for clinical decision-maling. Clin Chem 2009; 55(1):85-92.
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  38. Berridge BR, Pettit S, Walker DB, Jaffe AS, Schultze AE, Herman E, Reagan WJ, Lipshultz SE, Apple FS. A translational approach to detecting drug-induced cardiac injury with cardiac troponins: Consensus and recommendations from the cardiac troponins biomarker working group of the Health and Environmental Sciences Institute. Am Hrt J 2009; 151(1):21-29.
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  39. Saab PG, Bang H, Williams RB, Powell LH, Schneiderman N, Thoresen C, Burg M, Keefe F, for the ENRICHD Investigators. The impact of cognitive behavioral group training on event-free survival in patients with myocardial infarction: The ENRICHD experience. J Psycho Res 2009; 67:45-56.
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  40. Peleg A, Jaffe AS, Hasin Y. Enzyme-linked immunoabsorbent assay for detection of human serine protease corin in blood. Clinica Chimica Acta 2009; 409(1-2):85-89.
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  41. Saenger AK, Jaffe AS. Requiem for a heavyweight: the demise of creatine kinase-MB. Circulation 2008 Nov 18; 118(21):2200-6.
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  42. Alpert JS, Thygesen K, White HD, Jaffe AS. Implications of the universal definition of myocardial infarction. Nature Clinical Practice Cardiovascular Medicine 2008 Nov; 5(11):678-9.
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  43. Arruda-Olson AM, Pellikka PA, Bursi F, Jaffe AS, Santrach PJ, Kors JA, Killian JM, Weston SA, Roger VL. Left ventricular function and heart failure in myocardial infarction: impact of the new definition in the community. Am Heart J 2008 Nov; 156(5):810-5. Epub 2008 Sep 09.
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  44. Hickson LJ, Cosio FG, El-Zoghby ZM, Gloor JM, Kremers WK, Stegall MD, Griffin MD, Jaffe AS. Survival of patients on the kidney transplant wait list: relationship to cardiac troponin T. Am J Transplant 2008 Nov; 8(11):2352-9. Epub 2008 Sep 10.
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  45. Alpert JS, Thygesen K, White HD, Jaffe AS. Implications of the universal definition of myocardial infarction. Nat Clin Pract Cardiovasc Med 2008 Nov; 5(11):678-9. Epub 2008 Sep 09.
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  46. Thygesen K, Alpert JS, Jaffe AS, White HD. Diagnostic application of the universal definition of myocardial infarction in the intensive care unit. Curr Opin Crit Care 2008 Oct; 14(5):543-8.
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  47. Alpert JS, Thygesen K, Jaffe A, White HD. Ischaemic heart disease - The universal definition of myocardial infarction: a consensus document. Heart 2008 Oct; 94(10):1335-41.
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  48. Trockel M, Burg M, Jaffe A, Barbour K, Taylor CB. Smoking behavior postmyocardial infarction among ENRICHD trial participants: Cognitive behavior therapy intervention for depression and low perceived social support compared with care as usual. Psychosom Med 2008 Oct; 70(8):875-82.
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  49. Carney RM, Steinmeyer B, Freedland KE, Blumenthal JA, Stein PK, Steinhoff WA, Howells WB, Berkman LF, Watkins LL, Czajkowski SM, Domitrovich PP, Burg MM, Hayano J, Jaffe AS. Nighttime heart rate and survival in depressed patients post acute myocardial infarction. Psychosom Med 2008 Sep; 70(7):757-63.
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  50. Carney RM, Steinmeyer B, Freedland KE, Blumenthal JA, Stein PK, Steinhoff WA, Howells WB, Berkman LF, Watkins LL, Czajkowski SM, Domitrovich PP, Burg MM, Hayano J, Jaffe AS. Nighttime heart rate and survival in depressed patients post acute myocardial infarction. Psychosom Med 2008 Sep; 70(7):757-63. Epub 2008 Aug 25.
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  51. Jaffe AS. Key issues in the developing synergism between cardiovascular imaging and biomarkers. Clin Chem 2008 Sep; 54(9):1432-42. Epub 2008 Aug 01.
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  52. Mockel M, Danne O, Muller R, Vollert JO, Muller C, Lueders C, Stork T, Frei U, Koenig W, Dietz R, Jaffe AS. Development of an optimized multimarker strategy for early risk assessment of patients with acute coronary syndromes. Clin Chim Acta 2008 Jul 17; 393(2):103-9. Epub 2008 Mar 27.
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  53. Hess EP, Thiruganasambandamoorthy V, Wells GA, Erwin P, Jaffe AS, Hollander JE, Montori VM, Stiell IG. Diagnostic accuracy of clinical prediction rules to exclude acute coronary syndrome in the emergency department setting: a systematic review. CJEM 2008 Jul; 10(4):373-82.
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  54. Hess EP, Thiruganasambandamoorthy V, Wells GA, Erwin P, Jaffe AS, Hollander JE, Montori VM, Stiell IG. Diagnostic accuracy of clinical prediction rules to exclude acute coronary syndrome in the emergency department setting: a systematic review. CJEM 2008 Jul; 10(4):373-82.
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  55. Hess EP, Thiruganasambandamoorthy V, Wells GA, Erwin P, Jaffe AS, Hollander JE, Montori VM, Stiell IG. Diagnostic accuracy of clinical prediction rules to exclude acute coronary syndrome in the emergency department setting: a systematic review. CJEM 2008 Jul; 10(4):373-82.
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  56. Hess EP, Thiruganasambandamoorthy V, Wells GA, Erwin P, Jaffe AS, Hollander JE, Montori VM, Stiell IG. Diagnostic accuracy of clinical prediction rules to exclude acute coronary syndrome in the emergency department setting: a systematic review. CJEM 2008 Jul; 10(4):373-82.
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  57. Hess EP, Thiruganasambandamoorthy V, Wells GA, Erwin P, Jaffe AS, Hollander JE, Montori VM, Stiell IG. Diagnostic accuracy of clinical prediction rules to exclude acute coronary syndrome in the emergency department setting: a systematic review. CJEM 2008 Jul; 10(4):373-82.
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  58. Carney RM, Freedland KE, Steinmeyer B, Blumenthal JA, Berkman LF, Watkins LL, Czajkowski SM, Burg MM, Jaffe AS. Depression and five year survival following acute myocardial infarction: a prospective study. J Affect Disord 2008 Jul; 109(1-2):133-8. Epub 2008 Jan 11.
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  59. Brune K, Katus HA, Moecks J, Spanuth E, Jaffe AS, Giannitsis E. N-terminal pro-B-type natriuretic peptide concentrations predict the risk of cardiovascular adverse events from antiinflammatory drugs: a pilot trial. Clin Chem 2008 Jul; 54(7):1149-57. Epub 2008 May 01.
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  60. Hess EP, Thiruganasambandamoorthy V, Wells GA, Erwin P, Jaffe AS, Hollander HE, Montori VM, Stiell IG. Diagnostic accuracy of clinical prediction rules to exclude acute coronary syndrome in the emergency department setting: a systematic review. CJEM 2008 Jul; 10(4):373-82.
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  61. Brune K, Katus HA, Moecks J, Spanuth E, Jaffe AS, Giannitsis E. N-terminal pro-B-type natriuretic peptide concentrations predict the risk of cardiovascular adverse events from antiinflammatory drugs: a pilot trial. Clin Chem 2008 Jul; 54(7):1149-57. Epub 2008 May 01.
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  62. Carney RM, Freedland KE, Steinmeyer B, Blumenthal JA, Berkman LF, Watkins LL, Czajkowski SM, Burg MM, Jaffe AS. Depression and five year survival following acute myocardial infarction: a prospective study. J Affect Disord 2008 Jul; 109(1-2):133-8. Epub 2008 Jan 11.
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  63. Möckel M, Danne O, Müller R, Vollert J, Müller C, Lueders C, Störk T, Frei U, Koenig W, Dietz R, Jaffe A. Development of an optimized multimarker strategy for early risk assessment of patients with acute coronary syndromes. Clin Chim Acta 2008 Jul; 393(2):103-109.
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  64. Karon BS, Wockenfus A, Scott R, Hartman SJ, McConnell JP, Santrach PJ, Jaffe AS. Aspirin responsiveness in healthy volunteers measured with multiple assay platforms. Clin Chem 2008 Jun; 54(6):1060-5. Epub 2008 Apr 17.
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  65. Miller WL, Kurien S, Warfield KT, Wood CM, Jaffe AS. Lack of association between worsening renal function and mortality in heart failure patients treated with nesiritide. Int J Cardiol 2008 May 23; 126(2):234-9 Epub 2007 May 7.
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  66. Miller WL, Kurien S, Warfield KT, Wood CM, Jaffe AS. Lack of association between worsening renal function and mortality in heart failure patients treated with nesiritide. Int J Cardiol 2008 May 23; 126(2):234-9. Epub 2007 May 07.
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  67. McConnell JP, Jaffe AS. Variability of lipoprotein-associated phospholipase A2 measurements. Clin Chem 2008 May; 54(5):932-933.
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  68. Kavsak PA, Ko DT, Newman AM, Lustig V, Palomaki GE, MacRae AR, Jaffe AS. Vascular versus myocardial dysfunction in acute coronary syndrome: are the adhesion molecules as powerful as NT-proBNP for long-term risk stratification? Clin Biochem 2008 Apr; 41(6):436-9. Epub 2007 Dec 27.
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  69. Kavsak PA, Newman AM, Ko DT, Palomaki GE, Lustig V, MacRae AR, Jaffe AS. Is a pattern of increasing biomarker concentrations important for long-term risk stratification in acute coronary syndrome patients presenting early after the onset of symptoms? Clin Chem 2008 Apr; 54(4):747-51.
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  70. Kavsak PA, Newman AM, Ko DT, Palomaki GE, Lustig V, MacRae AR, Jaffe AS. Is a pattern of increasing biomarker concentrations important for long-term risk stratification in acute coronary syndrome patients presenting early after the onset of symptoms? Clin Chem 2008 Apr; 54(4):747-51.
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  71. Kavsak PA, Ko DT, Newman AM, Lustig V, Palomaki GE, MacRae AR, Jaffe AS. Vascular versus myocardial dysfunction in acute coronary syndrome: are the adhesion molecules as powerful as NT-proBNP for long-term risk stratification? Clin Biochem 2008 Apr; 41(6):436-9. Epub 2007 Dec 27.
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  72. Perez EA, Suman VJ, Davidson NE, Sledge GW, Kaufman PA, Hudis CA, Martino S, Gralow JR, Dakhil SR, Ingle JN, Winer EP, Gelmon KA, Gersh BJ, Jaffe AS, Rodeheffer RJ. Cardiac safety analysis of doxorubicin and cyclophosphamide followed by paclitaxel with or without trastuzumab in the North Central Cancer Treatment Group N9831 adjuvant breast cancer trial. J Clin Oncol 2008 Mar 10; 26(8):1231-8. Epub 2008 Feb 04.
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  73. Perez EA, Suman VJ, Davidson NE, Sledge GW, Kaufman PA, Hudis CA, Martino S, Gralow JR, Dakhil SR, Ingle JN, Winer EP, Gelmon KA, Gersh BJ, Jaffe AS, Rodeheffer RJ. Cardiac safety analysis of doxorubicin and cyclophosphamide followed by paclitaxel with or without trastuzumab in the North Central Cancer Treatment Group N9831 adjuvant breast cancer trial. J Clin Oncol 2008 Mar 10; 26(8):1231-8 Epub 2008 Feb 4.
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  74. Lopez-Jimenez F, Wu CO, Tian X, O'Connor C, Rich MW, Burg MM, Sheps D, Raczynski J, Somers VK, Jaffe AS. Weight change after myocardial infarction--the Enhancing Recovery in Coronary Heart Disease patients (ENRICHD) experience. Am Heart J 2008 Mar; 155(3):478-84. Epub 2008 Jan 15.
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  75. Lopez-Jimenez F, Wu CO, Tian X, O'Connor C, Rich MW, Burg MM, Sheps D, Raczynski J, Somers VK, Jaffe AS. Weight change after myocardial infarction--the Enhancing Recovery in Coronary Heart Disease patients (ENRICHD) experience. Am Heart J 2008 Mar; 155(3):478-84.
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  76. Writing Group Members, Apple FS, Wu AH, Jaffe AS, Panteghini M, Christenson RH, NACB Committee Members, Christenson RH, Apple FS, Cannon CP, Frances GS, Jesse RL, Morrow DA, Newby LK, Storrow AB, Tang WH, Wu AH, IFCC Committee on Standardization of Marker National Academy of Clinical Biochemistry and IFCC Committee for Standardization of Markers of Cardiac Damage Laboratory Medicine Practice Guidelines: Analytical Issues for Biomarkers of Heart Failure. Clin Biochem 2008 Mar; 41(4-5):222-6. Epub 2007 Nov 26.
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  77. Dal-Bianco JP, Jaffe AS, Bell MR, Oh JK. Cardiac function and brain-type natriuretic peptide in first-time flash pulmonary edema. Mayo Clin Proc 2008 Mar; 83(3):289-96.
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  78. Babuin L, Vasile VC, Rio Perez JA, Alegria JR, Chai HS, Afessa B, Jaffe AS. Elevated cardiac troponin is an independent risk factor for short- and long-term mortality in medical intensive care unit patients. Crit Care Med 2008 Mar; 36(3):759-65.
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  79. Apple FS, Wu AHB, Jaffe AS, Panteghini M, Christenson RH. National Academy of Clinical Biochemistry and IFCC committee for standardization of markers of cardiac damage laboratory medicine practice guidelines: Analytical issues for biomarkers of heart failure. Clin Biochem 2008 Mar; 41(4-5):222-6.
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  80. Apple FS, Wu AH, Jaffe AS, Panteghini M, Christenson RH, NACB Committee, Ifcc C-Smcd. National Academy of Clinical Biochemistry and IFCC Committee for Standardization of Markers of Cardiac Damage Laboratory Medicine Practice Guidelines: analytical issues for biomarkers of heart failure. Clin Biochem 2008 Mar; 41(4-5):222-6. Epub 2007 Nov 26.
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  81. Moller JE, Bergeron S, Jaffe A, Pellikka PA. Influence of left ventricular filling pattern on exercise-induced changes of natriuretic peptides in patients with suspected coronary artery disease. Int J Cardiol 2008 Feb 29; 124(2):204-10. Epub 2007 Apr 18.
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  82. Moller JE, Bergeron S, Jaffe A, Pellikka PA. Influence of left ventricular filling pattern on exercise-induced changes of natriuretic peptides in patients with suspected coronary artery disease. Int J Cardiol 2008 Feb 29; 124(2):204-10 Epub 2007 Apr 18.
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  83. Wu AH, Jaffe AS. The clinical need for high-sensitivity cardiac troponin assays for acute coronary syndromes and the role for serial testing. Am Heart J 2008 Feb; 155(2):208-14. Epub 2007 Dec 19.
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  84. Wu AH, Jaffe AS. The clinical need for high-sensitivity cardiac troponin assays for acute coronary syndromes and the role for serial testing. Am Heart J /-214 2008 Feb; 155(2):208-214.
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  85. Giannitsis E, Steen H, Kurz K, Ivandic B, Simon AC, Futterer S, Schild C, Isfort P, Jaffe AS, Katus HA. Cardiac magnetic resonance imaging study for quantification of infarct size comparing directly serial versus single time-point measurements of cardiac troponin T. J Am Coll Cardiol 2008 Jan 22; 51(3):307-14.
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  86. Giannitsis E, Steen H, Kurz K, Ivandic B, Simon AC, Futterer S, Schild C, Isfort P, Jaffe AS, Katus HA. Cardiac magnetic resonance imaging study for quantification of infarct size comparing directly serial versus single time-point measurements of cardiac troponin T. J Am Coll Cardiol 2008 Jan 22; 51(3):307-14.
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  87. Kavsak PA, Ko DT, Newman AM, Palomaki GE, Lustig V, Macrae AR, Jaffe AS. "Upstream markers" provide for early identification of patients at high risk for myocardial necrosis and adverse outcomes. Clin Chim Acta 2008 Jan; 387(1-2):133-8.
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  88. Kavsak PA, Ko DT, Newman AM, Palomaki GE, Lustig V, Macrae AR, Jaffe AS. "Upstream markers" provide for early identification of patients at high risk for myocardial necrosis and adverse outcomes. Clin Chim Acta 2008 Jan; 387(1-2):133-8. Epub 2007 Oct 03.
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  89. Arruda-Olson AM, Pellikka PA, Bursi F, Jaffe AS, Santrach PJ, Kors J, Killian JM, Weston SA, Roger VL. Left ventricular function and heart failure in myocardial infarction: impact of the new definition in the community. Am Heart J 2008; 158:810-5.
    View PubMed
  90. Moller JE, Bergeron S, Jaffe AS, Pellikka PA. Influence of left ventricular filling pattern on exercise-induced changes of natriuretic peptides in patients with suspected coronary artery disease. Int J Cardiol 2008; 124(2):204-10.
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  91. Prasad A, Rihal CS, Lennon RJ, Singh M, Jaffe AS, Holmes DR Jr. Significance of periprocedural myonecrosis on outcomes after percutaneous coronary intervention: an analysis of preintervention and postintervention troponin T levels in 5487 patients. Circ Cardiovasc Intervent 2008; 1:10-19.
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  92. Kavsak PA, MacRae AR, Yerna MJ, Jaffe AS. Analytical and clinical utility of a next generation, highly sensitive cardiac troponin I assay for early detection of myocardial injury. Clin Chem 2008.
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  93. Saenger AK, Jaffe AS. Requiem for a heavyweight. Circ 2008; 118:2200-2206.
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  94. Hess EP, Wells GA, Jaffe A, Stiell IG. A study to derive a clinical decision rule for triage of emergency department patients with chest pain: design and methodology. BMC Emerg Med 2008; 8:3. Epub 2008 Feb 06.
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  95. Dal-Bianco J, Jaffe AS, Bell MR, Oh JK. Cardiac Function and BNP in First Time Flash Pulmonary Edema. Mayo Clinic Proc 2008; 83(3):289-96.
    View PubMed
  96. Jaffe AS. The clinical impact of the universal diagnosis of myocardial infarction. Clin Chem Lab Med 2008; 46(11):1485-8.
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  97. Carney RM, Freedland KE, Steinmeyer B, Blumenthal JA, de Jonge P, Davidson KW, Czajkowski SM, Jaffe AS. History of depression and survival following acute myocardial infarction. Psycho Med 2008; (in press).
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  98. Kavsak PA, Ko DT, Newman AM, Palomaki GE, Lustig V, MacRae AR, Jaffe AS. Risk stratification for heart failure and death in an acute coronary syndrome population using inflammatory cytokines and N-terminal pro-brain natriuretic peptide. Clin Chem 2007 Dec; 53(12):2112-8. Epub 2007 Oct 11.
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  99. Wu AHB, Jaffe AS, Apple FS, Jesse RL, Francis GL, Morrow DA, Newby LK, Ravkilde J, Tang WHW, Christenson RH, Cannon CP, Storrow AB. National Academy of Clinical Biochemistry Laboratory Medicine Practice Guidelines: Use of cardiac troponin and B-type natriuretic peptide or N-terminal proB-type natriuretic peptide for etiologies other than acute coronary syndromes and heart failure. Clin Chem 2007 Dec; 53(12):2086-96.
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  100. Feng D, Edwards WD, Oh JK, Chandrasekaran K, Grogan M, Martinez MW, Syed II, Hughes DA, Lust JA, Jaffe AS, Gertz MA, Klarich KW. Intracardiac thrombosis and embolism in patients with cardiac amyloidosis. Circulation 2007 Nov 20; 116(21):2420-6.
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  101. Lee-Lewandrowski E, Januzzi JL, Green SM, Tannous B, Wu AH, Smith A, Wong A, Murakami MM, Kaczmarek J, Apple FS, Miller WL, Hartman K, Jaffe AS. Multi-center validation of the Response Biomedical Corporation RAMP NT-proBNP assay with comparison to the Roche Diagnostics GmbH Elecsys proBNP assay. Clin Chim Acta 2007 Nov-Dec; 386(1-2):20-4. Epub 2007 Jul 25.
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  102. Schulz O, Paul-Walter C, Lehmann M, Abraham K, Berghoefer G, Schimke I, Jaffe AS. Usefulness of detectable levels of troponin, below the 99th percentile of the normal range, as a clue to the presence of underlying coronary artery disease. Am J Cardiol 2007 Sep 1; 100(5):766-71.
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  103. Binder J, Ommen SR, Chen HH, Ackerman MJ, Tajik AJ, Jaffe AS. Usefulness of brain natriuretic peptide levels in the clinical evaluation of patients with hypertrophic cardiomyopathy. Am J Cardiol 2007 Aug 15; 100(4):712-4. Epub 2007 Jun 19.
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  203. Alpert JS, Antman E, Apple F, Armstrong PW, Bassand JP, de Luna G, Breithardt G, Chaitman BR, Clemmensen P, Falk E, Fishbein MC, Galvani M, Garson A, Grines C, Hamm C, Jaffe AS, Katus H, Kjekshus J, Klein W, Klootwijk P, Lenfant C, Levy D, Levy RI, Luepke Myocardial infarction redefined - A consensus document of the Joint European Society of cardiology/American College of Cardiology Committee for the Redefinition of Myocardial Infarction. Journal of the American College of Cardiology 2000 Sep; 36(3):959-69.
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  207. Berkman LF, Blumenthal J, Burg M, Carney RM, Catellier D, Cowan MJ, Czajkowski SM, DeBusk R, Hosking J, Jaffe A, Kaufmann PG, Mitchell P, Norman J, Powell LH, Raczynski JM, Schneiderman N. Enhancing recovery in coronary heart disease (ENRICHD) patients study: Study design and methods. American Heart Journal 2000; 139:1-9.
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  208. Freedland KE, Rich MW, Skala JA, Carney RM, Davila-Roman VG, Jaffe AS. Prevalence of depression in hospitalized patients with congestive heart failure. Psychosom Med 2000; 66:639-47.
  209. Carney RM, Freedland KE, Veith RC, Cryer PE, Skala JA, Lynch T, Jaffe AS. Major depression, heart rate, and plasma norepinephrine in patients with coronary heart disease. Biol Psychiatry 1999 Feb 15; 45(4):458-63.
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  210. Carney RM, Freedland EK, Veith RC, Jaffe AS. Can treating depression reduce mortality after an acute myocardail infarction? Psychosomatic Medicine 1999; 61:666-75.
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  211. Ottani F, Galvani M, Ferrini D, Ladenson JH, Puggioni R, Destro A, Baccos D, Bosi S, Ronchi A, Rusticali, Jaffe AS. Direct comparison of early elevations of cardiac troponin T and I in patients with unstable angina. AHJ 1999; 137:284-91.
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  212. Jaffe AS. Pandora's box is torn asunder. American Heart Journal July 1999; 138(1Pt 1):9-12.
  213. Jaffe AS. 2001--a biomarker odyssey. Clin Chim Acta 1999 Jun 30;284(2):197-211.
  214. Jaffe AS. The use of troponin measurements in patients with unstable angina. International Journal of Cardiology 68 Suppl 1999; 1:S49-53.
  215. Carney RM, Freedland KE, Eisen SA, Rich MW, Skala JA, Jaffe AS. Adherence to a prophyllactic medication regimen in patients with symptomatic vs asymptomatic ischemic heart disease Behavioral Medicine 1998; 24:35-9.
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  216. Jaffe AS, Landau WM, Wetzel RD. Resuscitation 2000: the need for improved databases in regard to neurological outcomes. Resuscitation 1998; 37:65-6.
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  217. Landt M, Lawson GM, Helgeson JM, Davila-Roman VG, Ladenson JH, Jaffe AS, Hickner RC. Prolonged exercise decreases serum leptin concentrations. Metabolism: Clinical & Experimental 1997 Oct; 46(10):1109-12.
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  218. Selis SP, Hom M, Sequeira JM, Tritel M, Gindea A, Ladenson JH, Jaffe AS, Esposito R. Time course of lysophosphatydylcholine relase from ischemic human myocardium parallels the time course of early ischemic ventricular arrhythmia Coron Art Disease 1997; 8:19-27.
  219. Davila-Roman V, Guest TH, Tuteur PG, Rowe WJ, Ladenson JH, Jaffe AS. Transient right but not left ventricular dysfunction after strenuous exercise at high altitude JACC 1997; 30:468-73.
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  220. Smith SC, Ladenson JH, Mason JW, Jaffe AS. Elevations of cardiac troponin I associated with myocarditis: Experimental and clinical correlates Circulation 1997; 95:163-8.
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  221. Hirsch R, Landt Y, Porter S, Canter CE, Jaffe AS, Ladenson JH, Grant JW, Landt M. Cardiac troponin I in Pediatrics: Normal values and potential use in the assessment of cardiac injury J Peds 1997; 130:827-72.
  222. Galvani M, Ottani F, Ferrini D, Ladenson JH, Destro A, Baccos D, Rusticali F, Jaffe AS. Prognostic influence of elevated values of cardiac troponin I in patients with unstable angina. Circulation 1997; 95:2053-9.
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  223. Allan JJ, Feld RD, Russell AA, Ladenson JH, Rogers MAM, Kerber RI, Jaffe AS. Cardiac troponin I levels are normal or minimally elevated after transthoracic cardioversion JACC 1997; 30:1052-6.
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  224. Jaffe AS. More rapid diagnosis of myocardial infarction: Is it worthwhile? American Family Physician 1997; 55:2591-2594.
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  225. Jaffe AS, Landt Y, Parvin CA, Abendschein DR, Geltman EM, Ladenson JH. Comparative sensitivity of cardiac troponin I and lactate dehydrogenase isoenzymes for the diagnosing acute myocardial infarction Clin Chem 1996; 42:1770-6.
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  226. Adams JE, Davila-Roman VG, Bessey PQ, Blake DP, Ladenson JH, Jaffe AS. Improved detection of cardiac contusion with cardiac troponin I Am Heart J 1996; 131:308-12.
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  227. Jaffe AS. Rationale for the use of conjunctive anticoagulation during thrombolysis. In Review in Depth Sobel BE Coron Art Dis 1996; 7:491-6.
  228. Fiedotin NA, Freedland KE, Carney RM, Skala JA, Rich MW, Jaffe AS. Depression, medical utilization in patients in chronic heart failure. Annuals of Behavioral Medicine 1996:S134.
  229. Carney RM, Freedland KE, Rich MW, Jaffe AS. Depression as a risk factor for cardiac events in established coronary heart disease: A review of possible mechanisms. Ann Behav Med 1995 Spring; 17(2):142-9.
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  230. Chaitman BR, Jaffe AS. What is the true periprocedure myocardial infarction rate? Does anyone know for sure? The need for clarification. Circulation 1995; 91:1609-10.
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  231. Carney RM, Freedland KE, Eisen SA, Rich MW, Jaffe AS. Major depression and medication adherence in elderly patients with coronary artery disease Health Psychology 1995; 14:88-90.
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  232. Carney RM, Saunders RD, Freedland KE, Stein P, Rich MW, Jaffe AS. Association of depression with reduced heart rate variability in coronary artery disease AJC 1995; 76:562-4.
  233. Grant JW, Canter CE, Spray TL, Landt Y, Saffitz JE, Ladenson JH, Jaffe AS. Elevated donor cardiac troponin I: A marker of acute graft failure in infant heart recipients Circulation 1994; 90:2618-21.
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  234. Lenke LG, Bridwel KH, Jaffe AS. Increase inc reatine kinase MB isoenzyme levels and spinal surgery J Spinal Disorders 1994; 7:70-6.
  235. Adams JE III, Schechtman K, Landt V, Landenson JH, Jaffe AS. Comparable detection of acute myocardial infarction by creatine kinase MB isoenzyme and cardiac troponin I Clin Chem 7 1994; 40:1291-5.
  236. Jaffe AS, Eisenberg PR, Abendschein DR. Conjoint use of MM and MB creatine kinase isoforms for detection of coronary recanalization Am Heart J 1994; 127:1461-6.
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  237. Adams JE, Sicard G, Allan BT, Bridwell KH, Lenke LG, Davila-Roman VG, Bodor GS, Ladenson JH, Jaffe AS. Diagnosis of perioperative myocardial infarction with masurement of cardiac troponin I N Engl J Med 1994; 330:670-4.
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  238. Adams JE III, Bodor GS, Davila-Roman VG, Delmez JA, Apple FS, Ladenson JH, Jaffe AS. Cardiac troponin I: A marker with high specificty for cardiac injury Circulation 1993; 88:101-6.
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  239. Goldstein JA, Tweddell JS, Barzilai B, Yagi Y, Jaffe AS, Cox JL. Hemodynamic effects of atrial ineraction Cor ARt Dis 1993; 4:545-53.
  240. Carney RM, Freedland KE, Rich MW, Smith LJ, Jaffe AS. Ventricular tachycardia and psychiatric depression in patients with coronary artery disease Am J Med 1993; 95:23-8.
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  241. Eisenberg MS, Aghababian RV, Bossaert L, Jaffe AS, Ornato JP, Weaver WD. Thrombolytic therapy. Ann Emerg Med 1993; 22:417-27.
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  242. Jaffe AS. More rapid biochemical diagnosis of myocardial infarction: Necessary? prudent? Clin Chem 1993; 39:1567-9.
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  243. Adams JE, Abendschein DR, Jaffe AS. Biochemical markers of myocardial injury: Is MB creatine kinase the choice for the 1990's? Circulation 1993; 88:750-63.
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  244. Jaffe AS, Landau WM. Clinical neuromythology XI death after death: The presumption of informed consent for CPR, ethical paradox, clinical conundrum. Neurology 1993; 43:2173-8.
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  245. Jaffe AS. The use of antiarrhythmias in advanced cardiac life support. Ann Emerg Med 1993; 22:307-16.
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  246. Jaffe AS, Deedwania PC, Higginson LA, Boden WE, Mehta JL, Ferlinz J, Walsh RA, Sullivan JM, Vokonas PS, Cabin H, et al. Diagnostic and therapeutic implications: exploration through case discussions. Am J Cardiol 1992 Nov 16; 70(16):45F-48F.
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  247. Jaffe AS. Effects of diabetes on the heart. (Overview) Cor Artery Dis 1992; 3:1-3.
  248. Jaffe AS. The use of intravenous diltiazem in patients with acute coronary artery disease. Am J Cardiol 1992; 69:25B-9B.
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  249. Jaffe AS, Deedwania PC, Higginson LAJ, Boden WE, Mehta JL, Ferlinz J, Walsh RA, Sullivan JM, Vokonas PS, Cabin H, Shapiro W, Parmley W. Diagnostic and therapeutic implicatins: Exploration through case discussion. Am J Cardiol 1992; 70:45F-48F.
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  250. Carney RM, Freedland KE, Smith LJ, Rich MW, Jaffe AS. Relation of depression and mortality after myocardial infarction in women. Circulation 1992; 84:1876-77.
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  251. Jaffe AS, Emergency Cardiac Care Committee. Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiac Care JAMA 1992; 268:2171-81.
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  252. Eisenberg PR, Sobel BE, Jaffe AS. Activation of prothrombin accompanying thrombolysis with rt-PA JACC 1992; 19:1065-9.
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  253. Goldstein JA, Tweddell JS, Barzilai B, Yagi Y, Jaffe AS, Cox JL. Importance of LV function and systolic ventricular interaction to right ventricular performance during acute right heart ischemia JACC 1992; 19:704-11.
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  254. Freedland KE, CArney RM, Lustman PJ, Rich MW, Jaffe AS. Major depression in coronary artery disease, patients with versus without a prior history of depression Psychosomatic Med 1992; 54:416-21.
  255. Carney RM, Freedland KE, Clark KA, Skala JA, Smith L, Delamater A, Jaffe AS. Psychosocial adjustment of patients arriving early at the emergency department after acute myocardial infarction Am J Cardiol 1992; 69:160-2.
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  256. Prager NA, Suzuki T, Jaffe AS, Sobel BE, Abendschein DR. The nature and time course of generation of isoforms of MB creatine kinase in vivo JACC 1992; 20:414-9.
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  257. Adams JE, Siegel BA, Goldstein JA, Jaffe AS. Elevations of CK-MB following pulmonary embolism: A manifestation of occult right ventricular infarction Chest 1992; 101:1203-6.
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  258. Goldstein JA, Kenzora JL, Jaffe AS. Coronary angiography with a novel mobile x-ray image intensifier Coronary ARtery Dis 1992; 3:1065-71.
  259. Abendschein DA, Ellis AK, Eisenberg PR, Klocke FJ, Sobel BE, Jaffe AS. Prompt detection of coronary recanalization by analysis of rates of change of concentrations of macromolecular markers in plasma Cor ARt Dis 1991; 2:201-12.
  260. Scharp DW, Lacy PE, Santiago JV, McCullough CS, Weide LG, Boyle PJ, Falqui L, Marchetti P, Ricordi C, Gingerich RL, Jaffe AS, Cryer PE, Hanto DW, Anderson CB, Flye MW. Results of our first nine intraportal islet allografts in type I insulin dependent diabetic patients Transplantation 1991; 51:76-85.
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  261. Goldstein JA, Tweddell JS, Barzilai B, Yagi Y, Jaffe AS, Cox JL. Right atrial ischemia exacerbates hemodynamic compromise associated with experimental right ventricular dysfunction JACC 1991; 18:564-72.
  262. Eisenberg PR, Kenzora J, Sobel BE, Ludbrook PA, Jaffe AS. Relation between ST segment shifts during ischemia and thrombin activity in patients with unstable angina JACC 1991; 18:893-903.
  263. Atkins JM, Mentzer RM, Field JM, Ornato JP, Francis CK, Passamani ER, Gibson RS, Prediman KS, Goldberg SJ, Smith HC, et al. Recommended guidelines for in-hospital cardiac monitoring of adults for detection of arrhythmia. Am Coll Cardiol 1991; 18(6):1431-3.
  264. Adams JE, Jaffe AS. Ischemic heart disease in patients with diabetes mellitus. Cont Intern Med 15-32 1991.
  265. Cummins RO, Ornato JP, Thies WH, Pepe PE, Billi JE, Seidel J, Jaffe AS, Flint LS, Goldstein S, Abramson NS, Brown C, Chandra NC, Gonzalez ER, Newell L, Stults KR, Membrino GE. Improving survival from sudden cardiac arrest: The "Chain of Survival" Concept. Circulation 1991; 83:1832-47.
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  267. Hartwell TD, Parker CB, Poole WK, Davis VG, Muller JE, Braunwald E, Robertson T, Rutherford J, Sobel BE, Strauss W, Thomas L, Roberts R, Jaffe AS, Willerson JT. Reproducibility of centralized laboratory interpretations of measures of myocardial infarct size, ventricular function, and ventricular electrical instability scintigraphy Coronary ARtery Disease 1991; 2:997-84.
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  268. Scharp DW, Lacy PE, Santiago JV, McCullough CS, Weide LG, Falqui L, Marchetti P, Gingerish RL, Jaffe AS, Cryer PE, Anderson CB, Flye MW. Insulin independence after Islet transplantation into Type I diabetic patient Diabetes 1990; 39:515-18.
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  269. Eisenberg PR, Lucore C, Kaufman L, Sobel BE, Jaffe AS, Rich S. Elevations of levels of fibrinopeptid A indicative of pulmonary vascular thrombosis in patient with primary pulmonary hypertension Circulation 1990; 82:841-7.
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  270. Carney RM, Freedland KE, Jaffe AS. Insomnia and Depression Prior to Myocardial Infarction Psychosomatic Medicine 1990; 52:603-9.
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  271. Winters KJ, Eisenberg PR, JAffe AS, Santoro SA. Dependence of plasmin-mediated degradation of platelet adhesive receptors on temperature and CA++ concentration Blood 1990; 76:1546-57.
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  272. Vered I, Vered Z, Perez JE, Jaffe AS, Whyte MP. Normal left ventricular function in children with x-linked hypophosphatemic rickets. A Doppler echocardiography study J Bone Min Res 1990; 5:469-74.
  273. Carney RM, Freeland KE, Ludbrook PA, Saunders RD, Jaffe AS. Major depression, panic disorder, and mitral valve prolapse in patients who complainof chest pain Am J Med 1990; 89:757-60.
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  274. Goldstein JA, Barzilai B, Rosamond TL, Eisenberg PR, Jaffe AS. Determinants of hemodynamic compromise with severe right ventricular infarction Circulation 1990; 82:469-368.
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  276. Barzilai B, Davis VG, Stone PH, Jaffe AS, MILIS study group. Prognostic significance fo mitral regurgitation in acute myocardial infarction AM J Cardiol 1990; 65:1169-75.
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  277. Cummins RO, Thies W, Paraskos J, Kerber RE, Billi JE, Seidel J, Jaffe AS, Flint L, Ornato JP, Abramson NS, Brown C, Chandra NC, Gonzales ER, Newell L, Stults KR, Membrino GE, Pepe PE. Encouraging early defibrillation: The American Heart Association and automated external defibrillation. Ann Emerg Med 1990; 19:1245-8.
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  279. Jaffe AS. Automated defibrillation: A problem, a challenge and an opportunity - The role of Internists and cardiologists in the prehospital care of their patients Cont Intern Med 8-1 1990.
  280. Anderson M, Atkins J, Austin D, Bili JE, Cummins RO, Eitel D, Graves J, Hambly C, Hudson C, Hudson J, Jaffe AS, Newman MM, Ornato JP, Stults KR, Thies WH, White RD. Instructors Manual for Advanced Cardiac Life Support chapter 6 and Supplement (Early Defibrillation) American Heart Association 1990.
  281. Cohen ML, Barzilai B, Gutierrez F, Jaffe AS, Eisenberg P. Treatment of prosthetic tricuspid valve thrombosis with low-dose tissue plasminogen activator. Am Heart J 1990; 120:978-9.
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  282. Devries S, Jaffe AS, Geltman EM, Sobel BE, Abendschein D. Enzymatic estimation of the extent of irreversible myocardial injury early after reperfusion. Am Heart J 1989; 117:31-6.
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  283. Jaffe AS, TIMI study group. Comparison of invaasive and conservative strategies after treatment with intravenous tissue plasminogen activator in acute myocardial infarction - Results of the thrombolysis in myocardial infarction (TIMI) phase II trial N Engl J Med 1989; 320:618-27.
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  284. Jaffe AS. New and old paradoxes: Acidosis and cardiopulmonary resuscitation. Circulation 1989; 80:1079-83.
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  285. Jaffe AS. Cardiovascular effects of diabetes. Curr Opin in Cardiol 1989; 4:711-20.
  286. Vered I, Vered Z, Perez JE, Jaffe AS, Whyte MP. Normal left ventricular performance documented by Doppler echocardiography in patients with longstanding hypocalcemia AM J Med 1989; 86:413-6.
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  287. Eisenberg PR, Shaw D, Schaab C, Jaffe AS. Concordance of creatine kinase-MB activity and mass Clin Chem 1989; 35:440-3.
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  288. Scharp D, Lacy P, Ricordi C, Boyle P, Santiago J, Cryer P, Gingerick R, Jaffe AS, Anderson C, Flye W. Human islet transplantation in patient with type-1 diabetes Transplant Proc 1989; 21:2744-5.
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  289. Carney RM, Freedland K, Rich MW, Jaffe AS. Stimulus induced analgesia and silent myocardial ischemia. J Appl Cardiol 1989; 4:271-4.
  290. Stone PH, Muller JE, Hartwell T, York BJ, Rutherford JD, Parker CB, Turi ZG, Strauss WH, Willerson JT, Sobel BE, Robertson T, Passamani E, Braunwald E, Jaffe AS, MILIS Study Group. The effect of diabetes mellitus on prognosis and serial left ventricular function after acute myocardial infarction: Contribution of both coronary disease and diastolic left ventricular dysfunction to the adverse prognosis J Am Coll Cardiol 1989; 14:49-57.
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  291. Lee RT, Lee TH, Poole WK, Gustafson N, Stone PH, Jaffe AS, Muller JE, Sobel BE, Braunwald E, MILIS study group. Rate of disappearance of creatine kinase and creatine kinase-MB after acute myocardial infarction. Clinical determinants of variability Am Heart J 1988; 116:661-4.
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  293. Stone PH, Raabe DS, Jaffe AS, Gustafson N, Muller JE, Turi ZG, Rutherford JD, Passamani E, Willerson JT, Sobel BE, Robertson T, Braunwald E, for the MILIS group. Prognostic significance of location and type of myocardial infarction. J Am Coll Cardiol 1988; 11:453-63.
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  294. Eisenberg PR, Miletich JP, Sobel BE, Jaffe AS. Differential effects of activation of prothrombin by streptokinase compared with urokinase and tissue-type plasminogen activator (t-PA). Thrombosis Res 1988; 50:707-17.
  295. Rao AK, Pratt C, Berke A, Jaffe AS, Ockene I, Schreiber TL, Bell Knatterud G, Robertson TL, Terrin ML, for the TIMI Investigators. The thrombolysis in myocardial infarction trial - Phase I. Hemorrhagic manifestations and changes in plasma fibrinogen and the fibrinolytic system in patients treated with recombinant tissue plasminogen activator and streptokinase J Am Col Cardiol 1988; 11:1-11.
  296. Kennedy JW, Atkins JM, Goldstein S, Jaffe AS, McIntyre KM, Mueller HS, Paraskos JA, Weaver WD. Recent changes in management of acute myocardial infarction: Implications for Emergency Care Physicians. J Am Coll Cardiol 1988; 11:446-9.
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  297. Eisenberg PR, Sobel BE, Jaffe AS. Characterization In Vivo of the fibrin specificity of activators of the fibrinolytic system. Circulation 1988; 78:592-7.
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  298. Jaffe AS, TIMI research group. Immediate versus delayed catheterization and angioplasty following thrombolytic therapy for acute myocardial infarction - TIMI IIA results. J Am Med Assoc 1988; 260:2849-58.
  299. Jaffe AS, Safdar S, Barzilai B, Semenkovich J, Saffitz J. Clinical Pathologic Conference: Carcinoma of the cervix with metastasis to the heart. Am J Med 1988; 84:463-74.
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  300. Jaffe AS, Montgomery WH, Donegan J, McIntyre KM et al. Instructors Manual for Advanced Cardiac Life Support, second edition. American Heart Association 1988.
  301. Eisen HJ, Barzilai B, Jaffe AS, Geltman EM. Relationship of QRS scoring system to enzymatic and pathologic infarct size: The role of infarct location. Am Heart J 1988; 115:993-1001.
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  302. Muller JE, Rude RE, Baunwald E, Hartwell TD, Roberts R, Sobel BE, Ritter C, Parker CB, Jaffe AS, Stone PH, Raabe DS, Willerson JT, Robertson T, MILIS study group. Myocardial infarct extension: Incidence, outcome, and risk factors in the MILIS study. Ann Intern Med 1988; 108:1-6.
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  303. Roberts R, Braunwald E, Muller JE, Croft C, Gold HK, Hartwell TD, Jaffe AS, Mullin SM, Parker C, Passamani ER, Poole K, Robertson T, Raabe DS, Rude RE, Stone PH, Turi ZG, Sobel BE, Willerson JT, MILIS study group. The effect of hyaluronidase on mortality and morbidity in patients with early peaking of plasma MB CK and nontransmural ischemia: Retrospective analysis of MILIS data. Br Heart J 1988; 60:290-8.
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  306. Eisenberg PR, Sherman LA, Perez J, Jaffe AS. Relationship between elevated plasma levels of crosslinked fibrin degradation products (XL-FDP) and the clinical presentation of patients with myocardial infarction. Thromb Res 1987; 46:109-20.
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  307. Gessler CJ, Jaffe AS. Hemodynamic monitoring and pacing with one catheter: A pilot study. Cath and Cardiovasc Diag 1987; 13:141-4.
  308. Eisenberg PR, Sherman LA, Tiefenbrunn AJ, Ludbrook PA, Sobel BS, Jaffe As. Sustained fibrinolysis after administration of t-PA despite ist short half life in the circulation. Thromb and Hemostasis 1987; 57:35-40.
  309. Tofler GH, Stone PH, Muller JE, Willich SN, Davis VKL, Poole WK, Strauss W, Willerson JT, Sobel BE, Jaffe AS, Robertson T, Passamani E, Braunwald E, MILIS study group. Effects of gender and race on prognosis after myocardial infarction: Adverse prognosis for women particularly black women. J Am Coll Cardiol 1987; 9:473-82.
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  310. Cox DA, Stone PH, Muller JE, Parker C, Hartwell TD, Rutherford JD, Roberts R, Jaffe AS, Hackel DB, Passamani E, Robertson T, Sobel BE, Willerson JT, Braunwald E, MILIS study group. Prognostic implications of an early peak in plasma MB creatine kinase patients with acute myocardial infarction. J Am Coll Cardiol 1987; 10:979-90.
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  311. Eisenberg PR, Sherman LA, Jaffe AS. Paradoxical elevation of fibrinopeptide A after streptokinase: Evidence for continued thrombosis despite intense fibrinolysis. JACC 1987; 10:527-9.
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  312. Jaffe AS, Biello DR, Sobel BE, Geltman EM. Enhancement of metabolism of jeopardized myocardium by nifedipine. Intern J Cardiol 1987; 15:77-89.
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  314. Carney RM, Rich M, teVelde A, Saini J, Clark K, Jaffe AS. Major depression disorder: A common psychiatric disorder in patients with coronary artery disease. Am J Cardiol 1987; 60:1273-5.
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  315. Barzilai B, Gessler C, Perez JE, Schaab C, Jaffe AS. Significance of Doppler detected mitral regurgitation acute myocardial infarction. Am J Cardiol 1987; 61:220-3.
  316. Jaffe AS, Albarran-Sotelo R, Atkins JM, Bloom RS et al. Textbook of advanced cardiac life support American Heart Association Textbook 1987.
  317. Jaffe AS, Sobel BE. Thrombolysis with tissue-type plasminogen activator in acute myocardial infarction. Potentials and pitfalls. JAMA 1986 Jan 10; 255(2):237-9.
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  322. Jaffe AS, Montgomery WH, Donegan J, McIntyre KM, et al. 1985 National Conference on Standards and Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiac Care. JAMA 1986; 255:2843-989.
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  324. Jaffe AS, MILIS study group. Hyaluronidase therapy for acute myocardial infarction: Results of a randomized, blinded, multicenter trial. Am J Cardiol 1986; 57:1236-43.
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  328. Stone PH, Turi ZG, Muller JE, Parker C, Hartwell T, Rutherford JD, Jaffe AS, Raabe DS, Passamani ER, Willerson JT, Sobel BE, Robertson TL, Braunwald E, MILIS study group. Prognostic significance of the exercise treadmill test performance six months after myocardial infarction. J Am Coll Cardiol 1986; 8:1007-17.
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  329. Jaffe AS, Serota H, Grace A, Sobel BE. Diagnostic changes in plasma creatine kinase isoforms early after the onset of acute myocardial infarction. Circulation 1986; 74:105-9.
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  330. Spadaro JJ, Ludbrook PA, Tiefenbrunn AJ, Kurnik PB, Jaffe AS. Paucity of subtle myocardial injury after angioplasty delineated with MB CK. Cath and Cardiovasc Dis 1986; 12:230-4.
  331. Muller JE, Turi ZG, Stone PH, Rude RE, Raabe DS, Jaffe AS, Gold HK, Gustafson N, Poole WK, Passamani E, Smith TW, Braunwald E, MILIS Study Group. Digoxin therapy and mortality following myocardial infarction: Experience in the MILIS study. N Eng J Med 1986; 314:265-71.
  332. Eisenberg PE, Sherman LA, Schechtman K, Sobel BE, Jaffe AS. Fibrinopeptide A: A marker of acute coronary thrombosis Circulation 1985; 71:912-8.
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  333. Turi ZG, Rutherford JD, Roberts R, Muller JE, Jaffe AS, Rude RE, Parker C, Raabe DS, Stone PH, Hartwell TD, Lewis SE, Parker RW, Gold HK, Robertson TL, Sobel BE, Willerson JT, Braunwald E, the Multicenter Investigation for the limitationof Infarct Size Electrocardiographic, enzymatic and scintigraphic criteria of acute myocardial infarction as determined from study of 726 patients Am J Cardiol 1985; 55:1463-8.
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  334. Lamas GA, Muller JE, Turi ZG, Stone PH, Rutherford JD, Jaffe AS, Raabe DS, Rude RE, Mark DB, Califf RM, Gold HK, Robertson T, Passamani ER, Braunwald E, MILIS study group. A simplified method to predict the occurence of complete heart block during acute myocardial infarction Am J Cardiol 1985; 57:1213-9.
  335. Eisenberg PR, Lee RG, Biello DR, Geltman EM, Jaffe AS. Chest pain after nontransmural infarction: The absence of remediable coronary vasospasm. Am Heart J 1985; 11:515-31.
  336. Semenkovich CF, Jaffe AS. Adverse effects due to morphine sulfate: A challenge to previous clinical doctrine Am J Med 1985; 79:325-30.
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  337. Jansen DE, Corbett JR, Lewis SE, Wolfe CL, Gabliani G, Filipchuk N, Redish G, Parkey RW, Buja M, Jaffe AS, Sobel BS, Willerson JT. Measurement of myocardial infarct size: A comparison of single photon emission computed tomography with pyrophosphate and serial CK-MB measurements Circulation 1985; 72:237-333.
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  338. Jaffe AS, TIMI Study Group. The thrombolysis in myocardial infarction (TIMI) trial - Phase I findings N Engl J Med 1985; 312:932-6.
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  339. Sedlis S, Saffitz J, Schwob V, Jaffe AS. Cardiac amyloidosis simulating hypertrophic myopathy. Am J Cardiol 1984; 53:969-70.
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  340. Hackel DB, Reimer KA, Ideker RE, Mikat EM, Hartwell TD, Parker CB, Braunwald EB, Gold HK, Jaffe AS, Raabe DS, Rude RE, Sobel BE, Stone PH, Buja M, Muller JE, Roberts R, MILIS Study Group. Comparison of enzymatic, anatomic estimates of myocardial infarct in man. Circulation 1984; 70:824-35.
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  341. Shafer KE, Santoro SA, Sobel BE, Jaffe AS. Monitoring activity of fibrinolytic therapy: A therapeutic challenge. Am J Med 1984; 75:879-86.
  342. Jaffe AS, Spadaro JJ, Schechtman K, Robert R, Geltman EM, Sobel BE. Increased congestive heart failure after infarction of modest extent in patients with diabetes mellitus. Am Heart J 1984; 108:31-7.
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  343. Jaffe AS, Garfinkel BT, Ritter CS, Sobel BE. Plasma, MB creatine kinase after vigorous exercise in professional athletes Am J Cardiol 1984; 53:856-8.
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  344. Mukharji J, Rude RE, Poole KW, Thomas LJ, Strauss HW, Jaffe AS, Muller JE, Roberts R, Raabe DS, Croft CH, Passamani E, Braunwald E, Willerson JT the MILIS Study Group. Late sudden death following acute myocardial infarction: Multivariate analysis of risk factors Am J Cardiol 1984; 54:31-6.
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  345. Jaffe AS, Ritter C, Meltzer V, Harter H, Roberts R. Unmasking artifactural increases in creatine kinase isoenzymes in patients with renal failure J Lab Clin Med 1984; 104:193-202.
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  346. Eisenberg PR, Jaffe AS, Schuster DP. Clinical evaluation compared to pulmonary artery catheterization in the hemodynamic assessment of critically-ill patients Crit Care Med 1984; 12:549-52.
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  347. Roberts R, Croft C, Gold HK, Tyler DH, Jaffe AS, Muller JE, Mullin SM, Parker C, Passamani ER, Poole WK, Raabe DS, Rude RE, Stone PH, Turi G, Sobel BE, Willerson JT, Braunwald E, MILIS Study Group. Effect of propranolol on myocardial infarct size in a randomized, blinded, multicenter trial N Engl J Med 1984; 311:218-25.
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  348. Sobel BE, Geltman EM, Tiefenbrunn AJ, Jaffe AS, Spadaro JJ, Ter-Pogossian MM, Collen D, Ludbrook PA. Improved regional myocardial metabolism after coronary thrombolysis iwth tissue-type plasminogen activator (t-PA) or streptokinase Circulation 1984; 69:983-9.
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  349. Jaffe AS, Lee R, Perez J, Geltman EM, Wilner G, Sobel BE. Lack of elevation of platelet factor IV in plasma from patient with myocardial infarction J Am Coll Cardiol 1984; 4:653-9.
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  350. Rosenblum AM, Ludbrook PA, Jaffe AS. Significance of elevated MB creatine kinase in patients after cardiac catheterization. Cardiac Catheter Diagn 1984; 10:547-52.
  351. Stone PH, Muller JE, Turi ZG, Geltman E, Jaffe AS, Braunwald E. Efficacy of nifedipine therapy in patients with refractory angina pectoris: Significance of the presence of coronary vasospasm Am Heart J 1983; 106:644-52.
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  352. Jaffe AS, Geltman EM, Tiefenbrunn AJ, Ambos HD, Strauss H, Sobel BE, Roberts R. Reduction in infarct size in patient with inferior infarction with intravenous nitroglycerin. A randomized prospective study. Br Heart J 1983; 49:452-69.
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  353. Billadello JJ, Smith JL, Ludbrook PA, Tiefenbrunn AJ, Jaffe AS, Sobel BE, Geltman EM. The implications of "Reciprocal" ST segment depression associated with acute myocardial infarction identified by positron tomography J Am Coll Cardiol 1983; 2:616-24.
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  354. Stone PH, Muller JE, Turi ZG, Geltman E, Jaffe AS, Braunwald E. Efficacy of nifedipine therapy in patients with refractory angina pectroris: Significance of the presence of coronary vasospasm. Arq Bras Cardiol 1983; 41:469-76.
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  355. Klahr S, Jaffe AS, McKeel T. Cyanotic Feet and Renal Failure in a 67-year-old man Am J Med 1983; 75:509-17.
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  356. Gutierrez FR, McKnight RC, Jaffe AS, Ludbrook PA, Biello D, Weldon CS. Double porcine valve replacement in carcinoid heart disease: A case report. Chest 1982; 181:101.
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  357. Jaffe AS, Robert R. Use of intravenous nitroglycerin in cardiovascular disease. Pharmacotherapy 1982; 2(5):273-8.
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  358. Clark KW, Geltman EM, Miller JP, Moore P, Madden KA, Thomas JJ, Hartwell TD, Jaffe AS, Rabbe DS, Stone PH, Gold HK, Rude RE, the MILIS Study Group. Reproducibility of dysrhythmia findings by a centralized laboratory within a major multicenter trial. 1982 Proceeding of Computers in Cardiology, Seattle, Washington. 1982.
  359. Jaffe AS, Geltman EM, Rodey GE, Uitto J. Mitral valve prolapse:A consistent manifestation of type IV Ehlers-Danlos Syndrome (the pathogenic role of abnormal type III collagen synthesis). Circulation 1981; 64:121.
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  360. Kornfeld S, Hruska K, Berger N, Jaffe AS, Shields H, DeSchriver K. Gastric outlet obstruction in patients with multiple myeloma. Am J Med 1980; 68:141-48.
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  361. Ahumada GG, Karlsberg RP, Jaffe AS, Ambos HD, Sobel BE, Roberts R. Reduction of early ventricular arrhythmias by acebutolol in patients with acute myocardial infarction Br Heart J 1979; 41:654.
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  362. Jaffe AS, Klein MS, Patel BR, Siegel BA, Roberts R. Abnormal technetium-99m pyrophosphate images in unstable angina: Ischemia versus infarction? Am J Cardiol 1979; 44:1035.
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  363. Srebro R, Jaffe AS. The origin of dark noise in foveal vision. J Optical Soc Am 1968; 58:1313.
  364. Guest TM, Ramanathan AV, Schechtman KB, Ladenson JH, Jaffe AS. Myocardial injury in critically ill medical patients: A surprisingly frequent complication JAMA 49 1995 1945-19; 273:1945-9.
  365. Miller WL, Hartman KA, Burritt MJ, Burnett JC, Jaffe AS. Troponin, B-Type Natriuretic Peptide Levels and Outcomes in Patients with Severe Heart Failure: Differences Between Ischemic and Idiopathic Dilated Cardiomyopathies. Clinical Cardiology 2007 May; 30(5):245-50.
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