Publications - Andrew McKeon, M.B., B.Ch., M.D.

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  1. Pittock SJ, Lennon VA, McKeon A, Mandrekar J, Weinshenker BG, Lucchinetti CF, O'Toole O, Wingerchuk DM. Eculizumab in AQP4-IgG-positive relapsing neuromyelitis optica spectrum disorders: an open-label pilot study. Lancet Neurol. 2013 Jun; 12(6):554-62. Epub 2013 Apr 26.
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  2. McKeon A, Lennon VA, LaChance DH, Klein CJ, Pittock SJ. Striational antibodies in a paraneoplastic context. Muscle Nerve. 2013 Apr; 47(4):585-7. Epub 2013 Mar 05.
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  3. O'Toole O, Lennon VA, Ahlskog JE, Matsumoto JY, Pittock SJ, Bower J, Fealey R, Lachance DH, McKeon A. Autoimmune chorea in adults. Neurology. 2013 Mar 19; 80(12):1133-44. Epub 2013 Feb 20.
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  4. O'Toole O, Murphy R, Tracy JA, McKeon A. Teaching NeuroImages: PET-CT hypermetabolism paralleling muscle hyperactivity in stiff-person syndrome. Neurology. 2013 Mar 5; 80(10):e109.
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  5. McKeon A. The importance of early and sustained treatment of a common autoimmune encephalitis. Lancet Neurol. 2013 Feb; 12(2):123-5. Epub 2013 Jan 03.
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  6. Klein CJ, Lennon VA, Aston PA, McKeon A, O'Toole O, Quek A, Pittock SJ. Insights from LGI1 and CASPR2 potassium channel complex autoantibody subtyping. JAMA Neurol. 2013 Feb; 70(2):229-34.
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  7. McKeon A, Martinez-Hernandez E, Lancaster E, Matsumoto JY, Harvey RJ, McEvoy KM, Pittock SJ, Lennon VA, Dalmau J. Glycine receptor autoimmune spectrum with stiff-man syndrome phenotype. JAMA Neurol. 2013 Jan; 70(1):44-50.
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  8. McKeon A, Lennon VA. Paediatric autoimmune encephalopathies: a lot done, more to do. J Neurol Neurosurg Psychiatry. 2012 Dec 18. [Epub ahead of print]
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  9. Klein CJ, Lennon VA, Aston PA, McKeon A, O'Toole O, Quek A, Pittock, SJ. Insights From LGI1 and CASPR2 Potassium Channel Complex Autoantibody Subtyping. Arch Neurol. 2012 Nov 26. [Epub ahead of print]
  10. Tillema JM, McKeon A. The spectrum of neuromyelitis optica (NMO) in childhood. J Child Neurol. 2012 Nov; 27(11):1437-47. Epub 2012 Aug 01.
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  11. Klaas JP, Ahlskog JE, Pittock SJ, Matsumoto JY, Aksamit AJ, Bartleson JD, Kumar R, McEvoy KF, McKeon A. Adult-Onset Opsoclonus-Myoclonus Syndrome. Arch Neurol. 2012 Sep 17; 69(12):1598-607. [Epub ahead of print]
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  12. Klein CJ, Lennon VA, Aston PA, McKeon A, Pittock SJ. Chronic pain as a manifestation of potassium channel-complex autoimmunity. Neurology. 2012 Sep 11; 79(11):1136-44. Epub 2012 Aug 15.
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  13. Quek AM, McKeon A, Lennon VA, Mandrekar JN, Iorio R, Jiao Y, Costanzi C, Weinshenker BG, Wingerchuk DM, Lucchinetti CF, Shuster EA, Pittock SJ. Effects of age and sex on aquaporin-4 autoimmunity. Arch Neurol. 2012 Aug; 69(8):1039-43.
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  14. Horta E, McKeon A, Lennon VA, Benarroch EE. Reversible paraneoplastic tonic pupil with PCA-Tr IgG and Hodgkin lymphoma. Neurology. 2012 May 15; 78(20):1620-2. Epub 2012 May 2.
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  15. Allen NM, McKeon A, O'Rourke DJ, O'Meara A, King MD. Excessive blinking and ataxia in a child with occult neuroblastoma and voltage-gated potassium channel antibodies. Pediatrics. 2012 May; 129(5):e1348-52. Epub 2012 Apr 23.
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  16. Quek AM, Britton JW, McKeon A, So E, Lennon VA, Shin C, Klein C, Watson RE Jr, Kotsenas AL, Lagerlund TD, Cascino GD, Worrell GA, Wirrell EC, Nickels KC, Aksamit AJ, Noe KH, Pittock SJ. Autoimmune epilepsy: clinical characteristics and response to immunotherapy. Arch Neurol. 2012 May; 69(5):582-93.
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  17. Wong-Kisiel LC, McKeon A, Wirrell EC. Autoimmune encephalopathies and epilepsies in children and teenagers. Can J Neurol Sci. 2012 Mar; 39(2):134-44.
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  18. Waters PJ, McKeon A, Leite MI, Rajasekharan S, Lennon VA, Villalobos A, Palace J, Mandrekar JN, Vincent A, Bar-Or A, Pittock SJ. Serologic diagnosis of NMO: a multicenter comparison of aquaporin-4-IgG assays. Neurology. 2012 Feb 28; 78(9):665-71; discussion 669. Epub 2012 Feb 01.
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  19. McKeon A, Robinson MT, McEvoy KM, Matsumoto JY, Lennon VA, Ahlskog JE, Pittock SJ. Stiff-man syndrome and variants: clinical course, treatments, and outcomes. Arch Neurol. 2012 Feb; 69(2):230-8.
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  20. Savica R, Kumar N, Ahlskog JE, Josephs KA, Matsumoto JY, McKeon A. Parkinsonism and dropped head: dystonia, myopathy or both? Parkinsonism Relat Disord. 2012 Jan; 18(1):30-4. Epub 2011 Aug 27.
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  21. McKeon A, Pittock SJ. Paraneoplastic encephalomyelopathies: pathology and mechanisms. Acta Neuropathol. 2011 Oct; 122(4):381-400. Epub 2011 Sep 22.
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  22. McKeon A, Tracy JA, Pittock SJ, Parisi JE, Klein CJ, Lennon VA. Purkinje cell cytoplasmic autoantibody type 1 accompaniments: the cerebellum and beyond. Arch Neurol. 2011 Oct; 68(10):1282-9. Epub 2011 Jun 13.
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  23. Somers KJ, Lennon VA, Rundell JR, Pittock SJ, Drubach DA, Trenerry MR, Lachance DH, Klein CJ, Aston PA, McKeon A. Psychiatric manifestations of voltage-gated potassium-channel complex autoimmunity. J Neuropsychiatry Clin Neurosci. 2011 Fall; 23(4):425-33.
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  24. Costanzi C, Matiello M, Lucchinetti CF, Weinshenker BG, Pittock SJ, Mandrekar J, Thapa P, McKeon A. Azathioprine: tolerability, efficacy, and predictors of benefit in neuromyelitis optica. Neurology. 2011 Aug 16; 77(7):659-66. Epub 2011 Aug 3.
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  25. Rudzinski LA, Pittock SJ, McKeon A, Lennon VA, Britton JW. Extratemporal EEG and MRI findings in ANNA-1 (anti-Hu) encephalitis. Epilepsy Res. 2011 Aug; 95(3):255-62. Epub 2011 May 12.
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  26. Flanagan EP, McKeon A, Lennon VA, Kearns J, Weinshenker BG, Krecke KN, Matiello M, Keegan BM, Mokri B, Aksamit AJ, Pittock SJ. Paraneoplastic isolated myelopathy: clinical course and neuroimaging clues. Neurology. 2011 Jun 14; 76(24):2089-95.
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  27. Cornelius JR, Pittock SJ, McKeon A, Lennon VA, Aston PA, Josephs KA, Tippmann-Peikert M, Silber MH. Sleep manifestations of voltage-gated potassium channel complex autoimmunity. Arch Neurol. 2011 Jun; 68(6):733-8.
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  28. Adams C, McKeon A, Silber MH, Kumar R. Narcolepsy, REM sleep behavior disorder, and supranuclear gaze palsy associated with Ma1 and Ma2 antibodies and tonsillar carcinoma. Arch Neurol. 2011 Apr; 68(4):521-4.
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  29. Dhamija R, Renaud DL, Pittock SJ, McKeon A, Lachance DH, Nickels KC, Wirrell EC, Kuntz NL, King MD, Lennon VA. Neuronal voltage-gated potassium channel complex autoimmunity in children. Pediatr Neurol. 2011 Apr; 44(4):275-81.
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  30. McKeon A, Pittock SJ, Lennon VA. CSF complements serum for evaluating paraneoplastic antibodies and NMO-IgG. Neurology. 2011 Mar 22; 76(12):1108-10.
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  31. Benarroch EE, McKeon A. Recurrent syncope as a manifestation of a dopamine-secreting glomus vagale tumor. Neurology. 2011 Mar 15; 76(11):1021-2.
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  32. McKeon A, Ahlskog JE, Britton JW, Lennon VA, Pittock SJ. "Reversible extralimbic paraneoplastic encephalopathies with large abnormalities on magnetic resonance images": Correction. Arch Neurol. 2011 Mar; 68(3):371.
  33. McKeon A, Lindell EP, Atkinson JL, Weinshenker BG, Piepgras DG, Pittock SJ. Pearls & oy-sters: clues for spinal dural arteriovenous fistulae. Neurology. 2011 Jan 18; 76(3):e10-2.
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  34. Apiwattanakul M, Popescu BF, Matiello M, Weinshenker BG, Lucchinetti CF, Lennon VA, McKeon A, Carpenter AF, Miller GM, Pittock SJ. Intractable vomiting as the initial presentation of neuromyelitis optica. Ann Neurol. 2010 Nov; 68(5):757-61.
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  35. Flanagan EP, McKeon A, Lennon VA, Boeve BF, Trenerry MR, Tan KM, Drubach DA, Josephs KA, Britton JW, Mandrekar JN, Lowe V, Parisi JE, Pittock SJ. Autoimmune dementia: clinical course and predictors of immunotherapy response. Mayo Clin Proc. 2010 Oct; 85(10):881-97.
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  36. Pittock SJ, Parisi JE, McKeon A, Roemer SF, Lucchinetti CF, Tan KM, Keegan BM, Hunter SF, Duncan PR, Baehring JM, Matsumoto JY, Lennon VA. Paraneoplastic jaw dystonia and laryngospasm with antineuronal nuclear autoantibody type 2 (anti-Ri). Arch Neurol. 2010 Sep; 67(9):1109-15.
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  37. Pittock SJ, Debruyne J, Krecke KN, Giannini C, van den Ameele J, De Herdt V, McKeon A, Fealey RD, Weinshenker BG, Aksamit AJ, Krueger BR, Shuster EA, Keegan BM. Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS). Brain. 2010 Sep; 133(9):2626-34. Epub 2010 Jul 17.
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  38. Hinson SR, McKeon A, Lennon VA. Neurological autoimmunity targeting aquaporin-4. Neuroscience. 2010 Jul 28; 168(4):1009-18. Epub 2009 Aug 20
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  39. Apiwattanakul M, McKeon A, Pittock SJ, Kryzer TJ, Lennon VA. Eliminating false-positive results in serum tests for neuromuscular autoimmunity. Muscle Nerve. 2010 May; 41(5):702-4.
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  40. McKeon A, Apiwattanakul M, Lachance DH, Lennon VA, Mandrekar JN, Boeve BF, Mullan B, Mokri B, Britton JW, Drubach DA, Pittock SJ. Positron emission tomography-computed tomography in paraneoplastic neurologic disorders: systematic analysis and review. Arch Neurol. 2010 Mar; 67(3):322-9. Epub 2010 Jan 11.
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  41. Lim SY, Mason WP, Young NP, Chen R, Bower JH, McKeon A, Pittock SJ, Lang AE. Polymyoclonus, laryngospasm, and cerebellar ataxia associated with adenocarcinoma and multiple neural cation channel autoantibodies. Arch Neurol. 2009 Oct; 66(10):1285-7.
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  42. Kale N, Pittock SJ, Lennon VA, Thomsen K, Roemer SF, McKeon A, Lucchinetti CF. Humoral MS Pathology (Pattern II) is not Associated with NMO-IgG Arch Neurol. 2009 Oct; 66(10):1298-9.
  43. Hinson SR, McKeon A, Fryer JP, Apiwattanakul M, Lennon VA, Pittock SJ. Prediction of neuromyelitis optica attack severity by quantitation of complement-mediated injury to aquaporin-4-expressing cells. Arch Neurol. 2009 Sep; 66(9):1164-7.
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  44. McKeon A, Fryer JP, Apiwattanakul M, Lennon VA, Hinson SR, Kryzer TJ, Lucchinetti CF, Weinshenker BG, Wingerchuk DM, Shuster EA, Pittock SJ. Diagnosis of neuromyelitis spectrum disorders: comparative sensitivities and specificities of immunohistochemical and immunoprecipitation assays. Arch Neurol. 2009 Sep; 66(9):1134-8.
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  45. McKeon A, Lennon VA, Lachance DH, Fealey RD, Pittock SJ. Ganglionic acetylcholine receptor autoantibody: oncological, neurological, and serological accompaniments. Arch Neurol. 2009 Jun; 66(6):735-41.
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  46. Magana SM, Matiello M, Pittock SJ, McKeon A, Lennon VA, Rabinstein AA, Shuster E, Kantarci OH, Lucchinetti CF, Weinshenker BG. Posterior reversible encephalopathy syndrome in neuromyelitis optica spectrum disorders. Neurology. 2009 Feb 24; 72(8):712-7.
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  47. McKeon A, Ahlskog JE, Britton JW, Lennon VA, Pittock SJ. Reversible extralimbic paraneoplastic encephalopathies with large abnormalities on magnetic resonance images. Arch Neurol. 2009 Feb; 66(2):268-71.
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  48. McKeon A, Ahlskog JE, Bower JH, Josephs KA, Matsumoto JY. Psychogenic tremor: long-term prognosis in patients with electrophysiologically confirmed disease. Mov Disord. 2009 Jan 15; 24(1):72-6.
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  49. McKeon A, Lennon VA, Jacob A, Matiello M, Lucchinetti CF, Kale N, Chan KH, Weinshenker BG, Apiwattinakul M, Wingerchuk DM, Pittock SJ. Coexistence of myasthenia gravis and serological markers of neurological autoimmunity in neuromyelitis optica. Muscle Nerve. 2009 Jan; 39(1):87-90.
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  50. McKeon A, Ahlskog JE, Bower JH, Josephs KA, Matsumoto JY. The outcomes of psychogenic tremor. Movement Disorders. 2009; 24:72-6.
  51. McKeon A, Ahlskog JE, Britton JA, Lennon VA, Pittock SJ. Paraneoplastic encephalopathies with large, reversible, lobar MRI abnormalities. Arch Neurol. 2009; 66:268-71.
  52. McKeon A, Matsumoto JY, Bower JH, Ahlskog JE. The spectrum of disorders presenting as adult-onset focal lower extremity dystonia. Parkinsonism Relat Disord. 2008 Dec; 14(8):613-9. Epub 2008 Mar 07.
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  53. McKeon A, Frye MA, Delanty N. The alcohol withdrawal syndrome. J Neurol Neurosurg Psychiatry. 2008 Aug; 79(8):854-62. Epub 2007 Nov 6
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  54. McKeon A, Lennon VA, Lotze T, Tenenbaum S, Ness JM, Rensel M, Kuntz NL, Fryer JP, Homburger H, Hunter J, Weinshenker BG, Krecke K, Lucchinetti CF, Pittock SJ. CNS aquaporin-4 autoimmunity in children. Neurology. 2008 Jul 8; 71(2):93-100. Epub 2008 May 28.
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  55. McKeon A, Ahlskog JE, Matsumoto JY. Psychogenic tremor occurring after deep brain stimulation surgery for essential tremor. Neurology. 2008 Apr 15; 70(16 Pt 2):1498-9.
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  56. McKeon A, Josephs KA, Klos KJ, Hecksel K, Bower JH, Michael Bostwick J, Eric Ahlskog J. Unusual compulsive behaviors primarily related to dopamine agonist therapy in Parkinson's disease and multiple system atrophy. Parkinsonism Relat Disord. 2007 Dec; 13(8):516-9. Epub 2007 Jun 04.
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  57. McKeon A, Marnane M, O'connell M, Stack JP, Kelly PJ, Lynch T. Potassium channel antibody associated encephalopathy presenting with a frontotemporal dementia like syndrome. Arch Neurol. 2007 Oct; 64(10):1528-30.
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  58. McKeon A, Pittock SJ, Glass GA, Josephs KA, Bower JH, Lennon VA, Ahlskog JE. Whole-body tremulousness: isolated generalized polymyoclonus. Arch Neurol. 2007 Sep; 64(9):1318-22.
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  59. Kumar N, McKeon A, Rabinstein AA, Kalina P, Ahlskog JE, Mokri B. Superficial siderosis and csf hypovolemia: the defect (dural) in the link. Neurology. 2007 Aug 28; 69(9):925-6.
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  60. McKeon A, Ozelius LJ, Hardiman O, Greenway MJ, Pittock SJ. Heterogeneity of presentation and outcome in the Irish rapid-onset dystonia-parkinsonism kindred. Mov Disord. 2007 Jul 15; 22(9):1325-7.
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  61. McKeon A, Vaughan C, Delanty N. Seizure versus syncope. Lancet Neurol. 2006 Feb; 5(2):171-80.
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  62. McKeon A, Murphy S, McNamara B, Ryder DQ, Galvin RJ. Isolated hypoglossal nerve palsy due to compression by a dissecting vertebral artery. Eur Neurol. 2005; 53(3):162-4. Epub 2004 May 28.
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  63. McKeon A, McNamara B, Sweeney B. Hashimoto’s encephalopathy presenting with psychosis and generalized absence status. J Neurol. 2004; 251:1025-7.


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