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Publications - Doo-Sup Choi, Ph.D.

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  1. Endres CJ, Moss AM, Govindarajan R, Choi DS, Unadkat JD. The role of nucleoside transporters in the erythrocyte disposition and oral absorption of ribavirin in the wild-type and equilibrative nucleoside transporter 1(-/-) mice. J Pharmacol Exp Ther 2009 Oct; 331(1):287-96.
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  2. Karpyak VM, Kim JH, Biernacka JM, Wieben ED, Mrazek DA, Black JL, Choi DS. Sequence variations of the human MPDZ gene and association with alcoholism in subjects with European ancestry. Alcohol Clin Exp Res 2009 Apr; 33(4):712-21. Epub 2009 Jan 21.
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  3. Chen J, Rinaldo L, Lim SJ, Young H, Messing RO, Choi DS. The type 1 equilibrative nucleoside transporter regulates anxiety-like behavior in mice. Genes Brain Behav 2007 Nov; 6(8):776-83. Epub 2007 Mar 21.
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  4. Choi DS, Wang D, Yu GQ, Zhu G, Kharazia VN, Paredes JP, Chang WS, Deitchman JK, Mucke L, Messing RO. PKCepsilon increases endothelin converting enzyme activity and reduces amyloid plaque pathology in transgenic mice. Proc Natl Acad Sci U S A 2006; 103(21):8215-20.
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  5. Chou WH, Choi DS, Zhang H, Mu D, McMahon T, Kharazia VN, Lowell CA, Ferriero DM, Messing RO. Neutrophil protein kinase C delta as a mediator of stroke-reperfusion injury. J Clin Invest 2004; 114:49-56.
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  6. Choi DS, Cascini MG, Mailliard W, Young H, Paredes P, McMahon T, Diamond I, Bonci A, Messing RO. The equilibrative nucleoside transporter type 1 modulates ethanol intoxication and preference in mice. Nat Neurosci 2004; 7:855-61.
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  7. Choi DS, Young H, McMahon T, Wang D, Messing RO. The mouse RACK1 gene is regulated by NF-kappa B and contributes to cell survival. Mol Pharmacol 2003; 64:1541-8.
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  8. Choi DS, Messing RO. Animal models in the study of protein kinase C isozymes. Methods Mol Biol 2003; 233:455-73.
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  9. Choi DS, Messing RO. Animal models to study the function of PKC isozymes. Methods Mol Biol 2003; 233:455-73.
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  10. Manivet P, Schneider B, Smith JC, Choi DS, Maroteaux L, Kellermann O, Launay JM. The serotonin binding site of human and murine 5-HT2B receptors: molecular modeling and site-directed mutagenesis. J Biol Chem 2002; 277:17170-8.
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  11. Choi DS, Wang D, Dadgar J, Chang WS, Messing RO. Conditional rescue of protein kinase C epsilon regulates ethanol preference and hypnotic sensitivity in adult mice. J Neurosci 2002; 22:9905-11.
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  12. Handa M, Choi DS, Caldeiro RM, Messing RO, Diamond I, Gordon AS. Cloning of a novel isoform of the NBMPR-sensitive equilibrative nucleoside transporter (ENT1) lacking a putative phosphorylation site. Gene 2001; 262:301-7.
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  13. Nebigil CG, Choi DS, Dierich A, Hickel P, Le Meur M, Messaddeq N, Launay JM, Maroteaux L. Serotonin 2B receptor is required for heart development. Proc Natl Acad Sci U S A 2000; 97:9508-13.
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  14. Choi DS, Handa M, Young H, Diamond I, Gordon AS, Messing RO. Genomic organization and expression of the mouse equilbrative, nitrobenzylthioinonosine sensitive nucleoside transporter 1 (ENT1) gene. Biochem Biophys Res Commun 2000; 277:200-8.
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  15. Choi DS, Wang D, Tolbert L, Sadée W. Basal signaling activity of dopamine D2L receptors demonstrated with an inducible mammalian expression system. J Neuroscience Meth 2000; 94:217-25.
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  16. Bolaños-Jiménez F, Choi DS, Maroteaux L. Preferential expression of 5-HT1D over 5-HT1B receptors during early embryogenesis. Neuroreport 1997; 8:3655-60.
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  17. Choi DS, Ward JS, Messaddeq N, Launay JM, Maroteaux L. 5-HT2B receptor-mediated serotonin morphogenetic functions in mouse cranial neural crest and myocardiac cells. Development 1997; 124:1745-55.
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  18. Choi DS, Loric S, Colas JF, Callebert J, Rosay P, Kellermann O, Maroteaux L. The mouse 5-HT2B receptor: homologous subtype or species variant? Behav Brain Res 1996; 73:253-7.
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  19. Choi DS, Maroteaux, L. Immunohistochemical localization of serotonin 5-HT2B receptor in mouse gut, cardiovascular system and brain. FEBS Lett 1996; 391:45-51.
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  20. Launay JM, Birraux G, Bondoux D, Callebert J, Choi DS, Loric S, Maroteaux L. Ras involvement signal transduction by the serotonin 5-HT2B receptor. J Biol Chem 1996; 271:3141-7.
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  21. Le Coniat M, Choi DS, Maroteaux L, Launay JM, Berger L. The 5-HT2B receptor gene maps to 2q36.3-2q37.1. Genomics 1996; 32:172-3.
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  22. Choi DS, Colas JF, Kellermann O, Loric S, Launay JM, Rosay P, Maroteaux L. The mouse 5-HT2B receptor: possible involvement in trophic functions of serotonin. Cell Mol Biol 1994; 40:403-11.
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  23. Choi DS, Birraux G, Launay JM, Maroteaux L. The human serotonin 5-HT2B receptor: pharmacological link between 5-HT2 and 5-HT1D receptors. FEBS Lett 1994; 352:393-9.
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