Publications - Evette S . Radisky, Ph.D.

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1. Salameh MA, Robinson JL, Navaneetham D, Sinha D, Madden BJ, Walsh PN, Radisky ES. The amyloid precursor protein/protease nexin 2 Kunitz inhibitor domain is a highly specific substrate of mesotrypsin. J Biol Chem 2009 Nov 17. [Epub ahead of print]
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2. Chen CS, Nelson CM, Khauv D, Bennett S, Radisky ES, Hirai Y, Bissell MJ, Radisky DC. Homology with vesicle fusion mediator syntaxin-1a predicts determinants of epimorphin/syntaxin-2 function in mammary epithelial morphogenesis. J Biol Chem 2009 Mar 13; 284(11):6877-84. Epub 2009 Jan 07.
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3. Salameh MA, Soares AS, Hockla A, Radisky ES. Structural basis for accelerated cleavage of bovine pancreatic trypsin inhibitor (BPTI) by human mesotrypsin. J Biol Chem 2008 Feb 15; 283(7):4115-23 Epub 2007 Dec 12.
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4. Salameh MA, Soares AS, Hockla A, Radisky ES. Structural basis for accelerated cleavage of bovine pancreatic trypsin inhibitor (BPTI) by human mesotrypsin. J Biol Chem 2008 Feb 15; 283(7):4115-23. Epub 2007 Dec 12.
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5. Radisky ES, Radisky DC. Stromal induction of breast cancer: Inflammation and invasion. Rev Endocr Metab Disord 2007 Sep; 8(3):279-87.
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6. Radisky ES, Radisky DC. Stromal induction of breast cancer: Inflammation and invasion. Rev Endocr Metab Disord 2007 Apr 20; Epub ahead of print.
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7. Radisky ES, Lee JM, Lu CJ, Koshland DE Jr. Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates. Proc Natl Acad Sci U S A 2006 May 2; 103(18):6835-40. Epub 2006 Apr 24.
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8. Radisky ES, Lu CJ, Kwan G, Koshland DE Jr. Role of the intramolecular hydrogen bond network in the inhibitory power of chymotrypsin inhibitor 2. Biochemistry 2005 May 10; 44(18):6823-30.
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9. Radisky ES, Kwan G, Karen Lu CJ, Koshland DE Jr. Binding, proteolytic, and crystallographic analyses of mutations at the protease-inhibitor interface of the subtilisin BPN'/chymotrypsin inhibitor 2 complex. Biochemistry 2004 Nov 2; 43(43):13648-56.
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10. Radisky ES, King DS, Kwan G, Koshland DE Jr. The role of the protein core in the inhibitory power of the classic serine protease inhibitor, chymotrypsin inhibitor 2. Biochemistry 2003 Jun 3; 42(21):6484-92.
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11. Radisky ES, Koshland DE Jr. A clogged gutter mechanism for protease inhibitors. Proc Natl Acad Sci U S A 2002 Aug 6; 99(16):10316-21.
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12. Radisky ES, Poulter CD. Squalene synthase: steady-state, pre-steady-state, and isotope-trapping studies. Biochemistry 2000 Feb 22; 39(7):1748-60.
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13. Wu Z, Demma M, Strickland CL, Radisky ES, Poulter CD, Le HV, Windsor WT. Farnesyl protein transferase: identification of K164 alpha and Y300 beta as catalytic residues by mutagenesis and kinetic studies. Biochemistry 1999 Aug 31; 38(35):11239-49.
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14. Ajioka RS, Jorde LB, Gruen JR, Yu P, Dimitrova D, Barrow J, Radisky E, Edwards CQ, Griffen LM, Kushner JP. Haplotype analysis of hemochromatosis: evaluation of different linkage-disequilibrium approaches and evolution of disease chromosomes. Am J Hum Genet 1997 Jun; 60(6):1439-47.
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15. Radisky ES, Ajioka RS, Edwards CQ, Griffen LM, Kushner JP. Mapping recombinant events with molecular markers in hemochromatosis pedigrees. Cytogenet Cell Genet 1994; 67(2):126-8.
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16. Radisky DC, Radisky ES, Barrows LR, Copp BR, Kramer RA, Ireland CM. Novel cytotoxic topoisomerase II inhibiting pyrroloiminoquinones from Fijian sponges of the genus Zyzzya. J Am Chem Soc 1993; 115:1632-8.
17. Yu Y, Radisky E, Leibold EA. The iron-responsive element binding protein. Purification cloning, and regulation in rat liver. J Biol Chem 1992 Sep 15; 267(26):19005-10.
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18. Garey JR, Harrison LM, Franklin KF, Metcalf KM, Radisky ES, Kushner JP. Uroporphyrinogen decarboxylase: a splice site mutation causes the deletion of exon 6 in multiple families with porphyria cutanea tarda. J Clin Invest 1990 Nov; 86(5):1416-22.
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