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Ann M. Reed, M.D.

Photo of Ann Reed M., M.D.
Ann M. Reed, M.D.
Location: Minnesota
  • Joint Appointment
  • Rheumatology
  • Pediatric and Adolescent Medicine
  • Academic Rank
  • Professor of Medicine
  • Professor of Pediatrics
Clinical Profile

Summary

Molecular Genetics and Genomics of juvenile dermatomyositis and other Pediatric Autoimmune disorders

In our Moleuclar Genetics Laboratory, we have identified genes that predispose children to Juvenile Dermatomyositis (JDM). We have identified not only the association with these genes, but the functional differences which exist in these genes that predispose to the disease. Our present focus includes the identification of the protective HLA genes in JDM, giving us a comprehensive understanding of the genetics of the disease. We are investigating the genetics of the T cell receptors and how the expression of these genes changes over the course of the illness and with treatment. Our group is also involved in international multicenter trials to establish outcome measures for disease activity and chronicity and looking for new agents to treat this disease both in adults and children.

Current studies include:

  • JDM studies of genes which influence age of onset, disease severity and presence of maternal cell chimerism
  • JDM studies of race specific disease genes
  • Studies of T cell receptor changes with disease and treatment
  • Gene expression arrays of the muscle tissue in JDM
  • Establishing outcome measures in Idiopathic Inflammatory Myositis
  • Theraputic trials with novel agents in JDM

Recent publications

See my publications

Education

Fellowship – Clinical Immunology/Rheumatology
Children's Memorial Hospital (Chicago)

Fellowship – Research training in a molecular genetics laboratory
University of Chicago

Fellowship – Department of Pediatrics, Division of Immunology/Rheumatology
Northwestern University Medical School

Residency – Pediatrics
Children's Hospital Medical Center of Akron

Internship – Pediatrics
Children's Hospital Medical Center of Akron

M.S.
Medical College of Ohio

B.A. – Biology/Zoology
University of Kentucky


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