Multidimensional Heart Imaging With Ultrasound
Noninvasive methods for measuring myocardial viscoelasticity are needed to assist with evaluation of heart function. The long-term goal of this program is to noninvasively measure and image heart wall mechanical properties with high accuracy and precision. For this purpose, researchers have developed shear wave dispersion ultrasound vibrometry (SDUV) techniques. The availability of noninvasive quantitative heart wall viscoelasticity measurements will support clinical evaluation and population studies.
Toward this objective, the following has been developed:
The outstanding record of achievements leads to the following specific goals for the next funding cycle of this program of research:
Successful completion of this program will result in a scientific and technological advancement in the field of ultrasonic imaging, providing the cardiologist with a direct quantitative measurement of the regional viscous and elastic compliance of the heart wall. Measurements will be fast enough to incorporate them in the typical cardiac ultrasound examination and allow evaluations at rest and during physiologic or pharmacologic interventions.
In this cardiology evaluation of SDUV, researcher will focus attention on hypertensive patients with diastolic heart failure — one of the largest populations that may benefit from direct measurements of myocardial viscoelastic properties. The lab anticipates the technology will provide quantitative measurements of myocardial properties with a wide variety of applications, such as ischemic heart disease, cardiomyopathies and heart transplant.
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