Grants
Active
- RO1 AR48147-05
Westendorf (PI)
08/01/02-07/31/11
NIH/NIAMS
Regulation of Runx2 Transcriptional Activity
The goals of this project are to define the role of HDAC3 during osteoblast development in vivo, and to determine how HDAC3-HDAC7-Runx2 complexes regulate osteoblast maturation in vitro.
Role: PI
- RO1 AR050074-03
Westendorf (PI)
05/15/04-03/31/08 (no cost extension)
NIH/NIAMS
Runx2 Transcriptional Control by Cell Signaling
The goal of this project is to define the mechanisms by which Lef1, a Wnt effecter, represses Runx2 activity and contributes to osteoblast maturation.
Role: PI
- RO1 AR050074-05S1
Westendorf (PI)
04/01/07-03/31/08
NIH/NIAMS
Runx2 Transcriptional Control by Cell Signaling
This is a supplement to an RO1 application of the same name. The goal is to generate a Lef1 knockout mouse through the NIH Knockout Mouse Project (KOMP).
Role: PI
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