Breast Cancer SPORE Grant Core Resources
The three Core Resources in the Mayo Clinic Breast Cancer SPORE are:
Core 1: Administrative Core
Director: James N. Ingle, M.D.
The Administrative Core is responsible for providing administrative and organizational support for the leadership of the Mayo Clinic Breast Cancer SPORE. It facilitates communication between Breast Cancer SPORE components, the Mayo Clinic Cancer Center, Mayo Clinic as a whole, other breast cancer SPOREs and the National Cancer Institute.
This core is crucial to the integration of all Breast Cancer SPORE activities and to effective and efficient oversight. The Administrative Core coordinates the activities of the Breast Cancer SPORE Executive Committee, the Mayo Clinic Inter-SPORE Advisory Committee, the Internal Scientific Advisory Committee and the External Advisory Committee.
This core also provides administrative support for the activities of the Breast Cancer SPORE Developmental Research and Career Development programs. The Administrative Core assists the SPORE director in coordinating and facilitating the research projects and ensuring the proper functioning of the cores in support of the translational research effort.
Core 2: Biospecimens and Pathology Core
Co-directors: Daniel W. Visscher, M.D.; and Wilma L. Lingle, Ph.D.
The Biospecimens and Pathology Core provides the biospecimens (frozen tissue, FFPE tissue, tissue microarrays and cell line microarrays, blood, serum, DNA, and RNA), pathology annotations, histological services, and pathology support necessary to support the projects of the Mayo Clinic Breast Cancer SPORE and other breast cancer translational research projects. The core also provides histology-related services, such as sectioning, immunostaining, antibody optimization and characterization, and digital imaging. Core pathologists provide immunohistochemistry interpretations. These functions are essential to most translational research, including the specific projects included in the Breast Cancer SPORE.
Core 3: Biostatistics and Patient Registry Core
Director: Vera J. Suman, Ph.D.
The Biostatistics and Patient Registry Core provides statistical collaboration and data management support for each of the Breast Cancer SPORE projects, the cores, the Developmental Research projects and the Career Development awardees.
Areas of support include:
Members of the Biostatistics and Patient Registry Core are also collaborating with other Mayo Clinic staff on an enterprisewide initiative to develop a virtual data warehouse that integrates elements of Mayo Clinic resources, including:
This collaborative effort will lead to a way to identify patient cohorts for Breast Cancer SPORE projects and to electronically populate some elements into the Breast Cancer Patient Registry.
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