Gene Analysis for the Understanding of Barrett's Esophagus and Esophagus Cancer
IRB Number : 495-01
Trial Status: Open for Enrollment
Why is this study being done?
This study is being done to advance the understanding of how esophagus cancer and Barrett's Esophagus develop as well as ways to treat these conditions. This will be done by analyzing blood and tissue to identify genes that may be involved in the development of esophagus cancer and Barrett's Esophagus.
Who is Eligible to Participate in the Study?
Men or women over the age of 18 who have esophagus cancer or Barrett's Esophagus.
Esophagus Cancer - there are two major types of esophagus cancer: Squamous cell cancer usually arises in the upper part of the esophagus. This type of cancer is most common in older men who use tobacco and alcohol. Adenocarcinoma commonly arises from Barrett's esophagus in the lower part of the esophagus. Although older men who smoke are at the greatest risk, Gastro Esophageal Reflux Disease (GERD) is an additional risk factor for this type of cancer. Barrett's Esophagus Barrett's esophagus is a complication of GERD. In Barrett's esophagus, reflux of gastric contents damage the normal lining of the lower esophagus, which is then replaced by a different type of lining. Patients with Barrett's esophagus have a much greater risk of developing esophagus cancer compared to the general population. Adenocarcinoma of the esophagus, which usually arises in a Barrett's esophagus, has been increasing in incidence in the United States by four to ten percent per year in recent decades. The cause of the increase is unknown. Similarly, the role of genetic factors in Barrett's esophagus is not known.
Additional Requirements / Information
What is involved in this research study? As a study participant you will be asked to:
Who can I Contact for Additional Information on this Trial?
If you wish to participate in our research study please contact Mary B. Fredericksen at 507-538-1887 or Debra Geno at 507-538-0367 or by Email.
What is/are the Locations of this Clinical Trial?
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