Publications

• Zhenyue Chen, Wei Huang, Tillman Dahme, Wolfgang Rottbauer, Michael J. Ackerman, Xiaolei Xu. Depletion of zebrafish essential and regulatory Myosin Light Chains reduces cardiac function through distinct mechanisms. Cardiovascular Research (in press), 2008.
• Xiaojing Sun, Ruilin Zhang, Xueying Lin, Xiaolei Xu. Wnt3a regulates the development of cardiac neural crest cells by modulating expression of crip2 in rhombomere 6. Circulation Research 102(7):831-39, 2008.
• Wang L, Dutta SK, Kojima T, Xiaolei Xu, Khosravi-Far R, Ekker SC, Mukhopadhyay D. Neuropilin-1 Modulates p53/Caspases Axis to Promote Endothelial Cell Survival. PLoS ONE. 2(11):e1161, 2007.
• Adam Rich, Scott Leddon, Simon J. Gibbons, Steven M. Miller, Xiaolei Xu and Gianrico Farrugia. Kit-like immunoreactivity in the zebrafish gastrointestinal tract reveals putative ICC. Developmental Dynamics 236(3):903-11, 2007.
• Xueying Lin, Lorenzo Rinaldo, Ahmed F. Fazly, Xiaolei Xu. Depletion of Med10 Enhances Wnt and Suppresses Nodal Signaling during Zebrafish Embryogenesis. Developmental Biology 303: 536-48, 2007.
• Michael Seeley, Wei Huang, Zhenyue Chen, William Oscar Wolff, Xueying Lin, Xiaolei Xu. Depletion of Zebrafish Titin Reduces Cardiac Contractility by Disrupting the Assembly of Z-discs and A-bands. Circulation Research 100(2):238-45, 2007 (cover page).
• Bos JM, Poley RN, Ny M, Tester DJ, Xiaolei Xu, Vatta M, Towbin JA, Gersh BJ, Ommen SR, Ackerman MJ. Genotype-phenotype relationships involving hypertrophic cardiomyopathy-associated mutations in titin, muscle LIM protein, and telethonin. Molecular Genetics and Metabolism 88(1):78-85, 2006.
• Ling Wang, Debabrata Mukhopadhyay, Xiaolei Xu. C terminus of RGS-GAIP-interacting protein conveys Neuropilin-1-mediated signaling during angiogenesis. FASEB Journal 2006 20(9): 1513-5
• Xiaolei Xu, Steffen E. Meiler, Tao P. Zhong, Manzoor Mohideen, Dane A. Crossley, Warren W. Burggren, Mark C. Fishman. Cardiomyopathy in zebrafish due to mutation in an alternatively spliced exon of titin. Nature Genetics 30(2): 205-9, 2002
• Stephane Zaffran, Xiaolei Xu, Patrick Lo, Hsiu-Hsiang Lee, Manfred Frasch. Cardiogenesis in the Drosophila model: control mechanisms during early induction and diversification of cardiac progenitors. Cold Spring Harbor Symposia on Quantitative Biology 67:1-12, 2002
• Xiaolei Xu, Zhizhang Yin, John B. Hudson, Edwin L. Ferguson, Manfred Frasch. Smad proteins act in combination with synergistic and antagonistic regulators to target Dpp responses to the Drosophila mesoderm. Genes & Development 12(15): 2354-70,1998
• Hanh T. Nguyen and Xiaolei Xu. Drosophila mef2 expression during mesoderm development is controlled by a complex array of cis-acting regulatory modules. Developmental Biology 204(2): 550-66, 1998
• Zhizhang Yin, Xiaolei Xu, Manfred Frasch. Regulation of the Twist target gene tinman by modular cis-regulatory elements during early mesoderm development. Development 124: 4971-82, 1997
• Yuhong Zhou, Xiaolei Xu, Zheng Liu, Shouyuan Zhao. Analysis of the transcriptional regulation by the 5'-upstream sequences of Tumor Necrosis Factor. Chinese Science Bulletin 37/1: 74-7, 1992