Publications

• Realini, C., Jensen, C., Zhang, Z.G., Johnston, S., Knowlton, J.R., Hill, C.P., & Rechsteiner, M. Characterization of Recombinant REGα, REGβ, and REGγ. Proteasome Activators. J. Biol. Chem. 1997; 272: 25483-25492.
• Knowlton, R., Johnston, R., Whitby, F., Realini, C., Zhang, Z.G., Rechsteiner, M., & Hill, C.P. Structure of the Proteasome Activator REGα. Nature 1997; 390: 639-643.
• Zhang, Z.G., Clawson, A., Realini, C., Jensen, C., Knowlton, J.R., Hill, C.P., & Rechsteiner, M. Identification of an Activation Region in the Proteasome Activator REGα.Proc. Natl. Acad. Sci. USA. 1998; 95: 2807-2811.
• Zhang, Z.G., Realini, C., Clawson, A., Endicott, S., & Rechsteiner, M. Proteasome Activation by REG Molecules Lacking Homolog-Specific Inserts. J. Biol. Chem. 1998; 273: 9501-9509.
• Zhang, Z.G., Clawson, A., & Rechsteiner, M. The Proteasome Activator 11S REG or PA28: Contribution by Both a and b Subunits to Proteasome Activation. J. Biol. Chem.1998; 273: 30660-30668.
• Zhang, Z.G., Krutchinsky, A., Endicott, S., Realini, C. Standing KG & Rechsteiner M. The Proteasome Activator 11S REG or PA28: Recombinant REGα/REGΒ Hetero-oligomers are Heptamers. Biochemistry 1999; 38: 5651-5658.
• Zhang, Z.G., Shibahara, K. & Stillman, B. PCNA connects DNA replication to epigenetic inheritance in yeast. Nature 2000; 408, 221-225.
• *Zhang, Z.G., *Hayashi, M.K., *Merkel, O., Stillman, B., and Xu, R.M. Structure and Function of the N-terminal BAH Domain of ORC1 in Transcriptional Silencing. EMBO J. 2002; 21: 4600-4611 (*equal contribution)
• Huang, S.B., Zhou, H., Katzmann, D., Hochstrasser, D., Atanasova, E.,& Zhang, Z.G. Rtt106p is a histone chaperone involved in heterochromatin mediated silencing. PNAS 2005, 102: 13410-5.
• Zhou, H., Madden, B., Muddiman, D., and Zhang Z.G. Chromatin assembly factor 1 interacts with histone H3 methylated at lysine 79 in the processes of epigenetic silencing and DNA repair. Biochemistry 2006 45: 2852-61.
• Han, J., Zhou, H., Horazdovsky, B., Zhang, K. and Xu, R. M. and Zhang, Z.G. Rtt109 acetylates histone H3  lysine 56 and functions in DNA replication. Science 2007, 315: 653-655.
• Huang, S., Zhou, H., Tarara, J., and Zhang, Z.G. A novel role of histone chaperones CAF-1 and Rtt106 in heterochromatin silencing. EMBO J. 2007; 26: 2274-2283.
• Collins, S.R., Miller, K.M., Maas, N.L., Roguev, A., Chu, C.S., Schuldiner, M., Gebbia, M., Cheng, B., Han, J., Recht, J., Fillingham, J., Ingvarsdottir, K., Shales, M., Erkmann, J.A., Ding, H., Xu, H., Andrews, B., Ingles, C., Boone, C., Emili, A., Kaufman, P.D., Allis, C.D., Berger, S.L., Brown, G.W., Hieter, P., Zhang, Z.G., Toczyski, D. P., Weissman, J.S., Greenblatt J. F. & Krogan N.F., Genetic interactions reveal the functional relationships within and between protein complexes involved in chromsome biology. Nature 2007; 446: 806-810.
• Han, J., Zhou, H., Li, Z., Xu, R. M. and Zhang, Z.G. The Rtt109-Vps75 histone acetyltransferase complex acetylates non-nucleosomal histone H3 J. Biol. Chem. 2007; 282: 14158-14164.
• Han, J., Zhou, H., Li, Z., Xu, R. M. and Zhang, Z.G. Acetylation of H3 lysine 56 catalyzed by Rtt109 and regulated by Asf1 is required for replisome integrity J. Biol. Chem (2007), In press.